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The map label for this gene is yugH [H]

Identifier: 49187761

GI number: 49187761

Start: 4663221

End: 4664411

Strand: Reverse

Name: yugH [H]

Synonym: BAS4771

Alternate gene names: 49187761

Gene position: 4664411-4663221 (Counterclockwise)

Preceding gene: 49187762

Following gene: 49187760

Centisome position: 89.21

GC content: 38.71

Gene sequence:

>1191_bases
ATGAAGCAATTTGAACTATCTAGAGCAGCAGAATCTCTACAACCATCTGGTATTCGAAAGTTTTTCGATTTAGCAGCAAA
TATGAAAGGTGTTATTTCTCTTGGGGTAGGAGAGCCTGATTTTGTTACACCTTGGAATGTGAGGCAAGCATGTATTCGTT
CTATAGAACAAGGATATACGTCATATACAGCAAATGCAGGATTATTGGAGCTCCGTCAAGAAATAGCAAAGTATCTAAAA
AAACAATTTGCAGTATCTTATGATCCAAACGATGAAATCATTGTTACAGTTGGAGCGAGTCAGGCGTTAGATGTAGCGAT
GCGCGCCATTATAAATCCTGATGATGAAGTACTTATTATTGAACCAAGCTTTGTTTCTTATGCACCGCTCGTAACTTTAG
CTGGAGGGGTTCCAGTTCCTGTGGCGACTACTTTAGAAAATGAGTTTAAAGTACAACCAGAACAAATTGAAGCAGCTATT
ACAGCGAAAACGAAGGCAATTTTACTTTGTTCACCAAATAACCCAACAGGTGCAATGTTGAATAAGTCCGAGCTTGAAGA
AATAGCAGTGATTGTTGAGAAGTACAATTTAATCGTATTATCTGATGAAATTTACGCAGAGCTTGTATACGACGAAGCAT
ATACAAGTTTCGCGAGTATTAAAAATATGCGTGAGCATACGATTTTAATTTCAGGATTTTCAAAAGGATTTGCGATGACA
GGGTGGCGCCTTGGTATGATTGCAGCTCCCGTTTATTTTTCGGAATTAATGCTCAAAATTCACCAATATTCCATGATGTG
TGCACCGACGATGTCTCAGTTTGCAGCACTTGAAGCGTTACGCGCGGGGAATGATGAAGTAATTCGGATGAGAGATAGTT
ATAAGAAACGCCGTAATTTTATGACGACATCTTTCAATGAAATGGGATTAACATGTCATGTGCCGGGCGGAGCATTTTAT
GTCTTTCCTTCTATTTCTTCAACTGGACTATCTTCGGCGGAATTTGCAGAACAGTTATTATTAGAAGAAAAAGTGGCTGT
TGTACCTGGAAGTGTATTTGGCGAAAGTGGTGAAGGATTTATTCGTTGTTCGTATGCAACATCGCTTGAACAACTTATGG
AAGCAATGAAGAGAATGGAACGGTTCGTAGAGAATAAAAAAAGGACAAAACACAATACGTTTTGTCCATAA

Upstream 100 bases:

>100_bases
CTGTCGTTTCTACGACAACGCATTTCATTTTGAAGAAGTATAAACATGAGGGAATTATTTATGAAAAAAACGATGATGAT
AAGCGAATTGTGGTGACACC

Downstream 100 bases:

>100_bases
AAGGGGGGGAATACTAGAAAGCCATGTGTTAGTATTCTACCCTAATATTGGAGAATTATACTTACTTAAGGAAATTTTTT
CATGAATTTTGAATGCGTCC

Product: hypothetical protein

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 396

Protein sequence:

>396_residues
MKQFELSRAAESLQPSGIRKFFDLAANMKGVISLGVGEPDFVTPWNVRQACIRSIEQGYTSYTANAGLLELRQEIAKYLK
KQFAVSYDPNDEIIVTVGASQALDVAMRAIINPDDEVLIIEPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPEQIEAAI
TAKTKAILLCSPNNPTGAMLNKSELEEIAVIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMREHTILISGFSKGFAMT
GWRLGMIAAPVYFSELMLKIHQYSMMCAPTMSQFAALEALRAGNDEVIRMRDSYKKRRNFMTTSFNEMGLTCHVPGGAFY
VFPSISSTGLSSAEFAEQLLLEEKVAVVPGSVFGESGEGFIRCSYATSLEQLMEAMKRMERFVENKKRTKHNTFCP

Sequences:

>Translated_396_residues
MKQFELSRAAESLQPSGIRKFFDLAANMKGVISLGVGEPDFVTPWNVRQACIRSIEQGYTSYTANAGLLELRQEIAKYLK
KQFAVSYDPNDEIIVTVGASQALDVAMRAIINPDDEVLIIEPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPEQIEAAI
TAKTKAILLCSPNNPTGAMLNKSELEEIAVIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMREHTILISGFSKGFAMT
GWRLGMIAAPVYFSELMLKIHQYSMMCAPTMSQFAALEALRAGNDEVIRMRDSYKKRRNFMTTSFNEMGLTCHVPGGAFY
VFPSISSTGLSSAEFAEQLLLEEKVAVVPGSVFGESGEGFIRCSYATSLEQLMEAMKRMERFVENKKRTKHNTFCP
>Mature_396_residues
MKQFELSRAAESLQPSGIRKFFDLAANMKGVISLGVGEPDFVTPWNVRQACIRSIEQGYTSYTANAGLLELRQEIAKYLK
KQFAVSYDPNDEIIVTVGASQALDVAMRAIINPDDEVLIIEPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPEQIEAAI
TAKTKAILLCSPNNPTGAMLNKSELEEIAVIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMREHTILISGFSKGFAMT
GWRLGMIAAPVYFSELMLKIHQYSMMCAPTMSQFAALEALRAGNDEVIRMRDSYKKRRNFMTTSFNEMGLTCHVPGGAFY
VFPSISSTGLSSAEFAEQLLLEEKVAVVPGSVFGESGEGFIRCSYATSLEQLMEAMKRMERFVENKKRTKHNTFCP

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=322, Percent_Identity=29.8136645962733, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI169881279, Length=322, Percent_Identity=29.8136645962733, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI56713256, Length=400, Percent_Identity=29.25, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI56713254, Length=400, Percent_Identity=29.25, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI169881281, Length=229, Percent_Identity=30.1310043668122, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI4507369, Length=412, Percent_Identity=26.9417475728155, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI187936925, Length=402, Percent_Identity=22.8855721393035, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI14211921, Length=402, Percent_Identity=22.8855721393035, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI149944424, Length=395, Percent_Identity=23.7974683544304, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI215599424, Length=367, Percent_Identity=22.3433242506812, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI7705897, Length=427, Percent_Identity=24.5901639344262, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI33469970, Length=427, Percent_Identity=24.5901639344262, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI19263340, Length=367, Percent_Identity=22.3433242506812, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=27.9778393351801, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI1788722, Length=367, Percent_Identity=27.7929155313352, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1788627, Length=370, Percent_Identity=27.5675675675676, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1790797, Length=377, Percent_Identity=24.6684350132626, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787909, Length=221, Percent_Identity=29.4117647058824, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787710, Length=328, Percent_Identity=21.6463414634146, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=378, Percent_Identity=32.2751322751323, Blast_Score=165, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=31.9261213720317, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17567369, Length=414, Percent_Identity=28.9855072463768, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17567663, Length=386, Percent_Identity=26.6839378238342, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71981209, Length=370, Percent_Identity=22.972972972973, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=333, Percent_Identity=27.6276276276276, Blast_Score=128, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320317, Length=376, Percent_Identity=22.8723404255319, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323118, Length=368, Percent_Identity=25, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322075, Length=245, Percent_Identity=24.8979591836735, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28573069, Length=417, Percent_Identity=27.8177458033573, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI24646114, Length=417, Percent_Identity=27.8177458033573, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28573067, Length=417, Percent_Identity=27.8177458033573, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI28573065, Length=417, Percent_Identity=27.8177458033573, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI18859735, Length=389, Percent_Identity=25.1928020565553, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24641770, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641760, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641768, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641766, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641764, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45551451, Length=393, Percent_Identity=24.6819338422392, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 43894; Mature: 43894

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFELSRAAESLQPSGIRKFFDLAANMKGVISLGVGEPDFVTPWNVRQACIRSIEQGYT
CCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCH
SYTANAGLLELRQEIAKYLKKQFAVSYDPNDEIIVTVGASQALDVAMRAIINPDDEVLII
HHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEE
EPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPEQIEAAITAKTKAILLCSPNNPTGAML
CCCHHHHCCHHHCCCCCCCCEEEECCCCCCCCHHHHHHHEEECEEEEEEECCCCCCCCCC
NKSELEEIAVIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMREHTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEC
GWRLGMIAAPVYFSELMLKIHQYSMMCAPTMSQFAALEALRAGNDEVIRMRDSYKKRRNF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCC
MTTSFNEMGLTCHVPGGAFYVFPSISSTGLSSAEFAEQLLLEEKVAVVPGSVFGESGEGF
CCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCE
IRCSYATSLEQLMEAMKRMERFVENKKRTKHNTFCP
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKQFELSRAAESLQPSGIRKFFDLAANMKGVISLGVGEPDFVTPWNVRQACIRSIEQGYT
CCCCCHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCH
SYTANAGLLELRQEIAKYLKKQFAVSYDPNDEIIVTVGASQALDVAMRAIINPDDEVLII
HHCCCCCHHHHHHHHHHHHHHHHEEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCEEEE
EPSFVSYAPLVTLAGGVPVPVATTLENEFKVQPEQIEAAITAKTKAILLCSPNNPTGAML
CCCHHHHCCHHHCCCCCCCCEEEECCCCCCCCHHHHHHHEEECEEEEEEECCCCCCCCCC
NKSELEEIAVIVEKYNLIVLSDEIYAELVYDEAYTSFASIKNMREHTILISGFSKGFAMT
CHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCEEC
GWRLGMIAAPVYFSELMLKIHQYSMMCAPTMSQFAALEALRAGNDEVIRMRDSYKKRRNF
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCC
MTTSFNEMGLTCHVPGGAFYVFPSISSTGLSSAEFAEQLLLEEKVAVVPGSVFGESGEGF
CCCCCCCCCCEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHCCCCCCCE
IRCSYATSLEQLMEAMKRMERFVENKKRTKHNTFCP
EEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377 [H]