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The map label for this gene is kinC [H]

Identifier: 49187659

GI number: 49187659

Start: 4561298

End: 4562518

Strand: Reverse

Name: kinC [H]

Synonym: BAS4668

Alternate gene names: 49187659

Gene position: 4562518-4561298 (Counterclockwise)

Preceding gene: 49187660

Following gene: 49187656

Centisome position: 87.26

GC content: 31.53

Gene sequence:

>1221_bases
ATGAATAAAGACGGTATATTTAAAAATGAAGAAATGAAGGCGCTAAAAATATTTTTAAGTTTATTTTTCATTATATTTTT
TGTATACGATCTTGCCTACGAATTTATTGTACCTTTAATAGGAGGAGAGCAAGAAGGAGTAGGACAATTTGAAGATGGTT
TAGGTTTATGGCTTTATTTTCTGATGGTGGTCCTATTTTGCACTGGAATATACTTTATGAAATGGAAGAATCCATTTGCA
GTGAAATATATTATACTAATTGGATATAATCTATTAGATTTTATCCATAATTTTATGATTTACTATGGTAGTGATGCTGA
GTTTGATGGTGGGAATATAGTAGAAGGATTTTTTATTTTATTTGCCCCACTCTTTGTGAATAAAAGATATTTTTGGTTAG
TTCCGAGCATACTTATTGGAAAATACGCTCTTACTGGAATCATCATTCACTCGTCACTCGTTTTAATCCCGATGGCATTA
TATGGCGTATTTACTATCATATGTTGGATTATGTTTTTAAGATTTCACTCTTACGTTCGCACGCTTGAGATGATGGATAA
AGAAATACAACAAACAGAAAAGCTAGCAACTGTTGGGAAAATGGCTACAGTTATTGGTTACAAAATTAAAAGACCTTTAG
CTAATTTAGATAAATTTGTTAATAAGCAAGCGATTAAATATCCAGAGGACAAAATATATAGTGATATTATGAAACAAGAA
GTAGAACGAATTCATATAATAGCTACAGAACTTAGTGGATTTGAGAAATCTAAATCAATAGAATCAGAAGTTCATAATAT
AGAAGAAATTATCGCTTATGTTATTCGAGTTATGGGGAAGCCTGCATTAAATCAAGGCGTGCACATACAAGGTATTTATA
GTAAAGACATACCATCGATTACATGCGATGAAAAACGATTAAAACAAGTATTTTTTAATTTAATTAAAAATGCGATTGAA
GCAATGTCAGTTGGCGGAACGATTACAATTAAAGTGACTGTAGAAGATGCAATCATTATTCAAGTGAAGGATGAGGGTTG
CGGCATTCCAAAAGAAAAAATTCCTAAGTTAAACGAAGCCTTTTACACAACGAAAGAAACGGGAACAGGTTTAGGTTTAG
TAGTTACAGAAAAAATTATTAAAGATCACAATGGTAAAATGAGTTTTGAAAGTGAAGTTGGGGTTGGAACGACGGTGAAG
GTTATGTTGCCGATACAATAA

Upstream 100 bases:

>100_bases
TTTCAAGTGAAAGAGATATTGGAACTAGAATAGATATCATTCTCCCGAAACAACGTGGAAATAGTGAAATCCAAGTGGGA
GAAAAGCTAGGAGTTACCAT

Downstream 100 bases:

>100_bases
AAAATATATTTTAAAAAGGGAAATCACTTACTTGAGAGTGATTTCCCTTTTTTGTGAATAAAAATCCGGAAGTGTTTACA
CTATTGGTGCATTATATATA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNKDGIFKNEEMKALKIFLSLFFIIFFVYDLAYEFIVPLIGGEQEGVGQFEDGLGLWLYFLMVVLFCTGIYFMKWKNPFA
VKYIILIGYNLLDFIHNFMIYYGSDAEFDGGNIVEGFFILFAPLFVNKRYFWLVPSILIGKYALTGIIIHSSLVLIPMAL
YGVFTIICWIMFLRFHSYVRTLEMMDKEIQQTEKLATVGKMATVIGYKIKRPLANLDKFVNKQAIKYPEDKIYSDIMKQE
VERIHIIATELSGFEKSKSIESEVHNIEEIIAYVIRVMGKPALNQGVHIQGIYSKDIPSITCDEKRLKQVFFNLIKNAIE
AMSVGGTITIKVTVEDAIIIQVKDEGCGIPKEKIPKLNEAFYTTKETGTGLGLVVTEKIIKDHNGKMSFESEVGVGTTVK
VMLPIQ

Sequences:

>Translated_406_residues
MNKDGIFKNEEMKALKIFLSLFFIIFFVYDLAYEFIVPLIGGEQEGVGQFEDGLGLWLYFLMVVLFCTGIYFMKWKNPFA
VKYIILIGYNLLDFIHNFMIYYGSDAEFDGGNIVEGFFILFAPLFVNKRYFWLVPSILIGKYALTGIIIHSSLVLIPMAL
YGVFTIICWIMFLRFHSYVRTLEMMDKEIQQTEKLATVGKMATVIGYKIKRPLANLDKFVNKQAIKYPEDKIYSDIMKQE
VERIHIIATELSGFEKSKSIESEVHNIEEIIAYVIRVMGKPALNQGVHIQGIYSKDIPSITCDEKRLKQVFFNLIKNAIE
AMSVGGTITIKVTVEDAIIIQVKDEGCGIPKEKIPKLNEAFYTTKETGTGLGLVVTEKIIKDHNGKMSFESEVGVGTTVK
VMLPIQ
>Mature_406_residues
MNKDGIFKNEEMKALKIFLSLFFIIFFVYDLAYEFIVPLIGGEQEGVGQFEDGLGLWLYFLMVVLFCTGIYFMKWKNPFA
VKYIILIGYNLLDFIHNFMIYYGSDAEFDGGNIVEGFFILFAPLFVNKRYFWLVPSILIGKYALTGIIIHSSLVLIPMAL
YGVFTIICWIMFLRFHSYVRTLEMMDKEIQQTEKLATVGKMATVIGYKIKRPLANLDKFVNKQAIKYPEDKIYSDIMKQE
VERIHIIATELSGFEKSKSIESEVHNIEEIIAYVIRVMGKPALNQGVHIQGIYSKDIPSITCDEKRLKQVFFNLIKNAIE
AMSVGGTITIKVTVEDAIIIQVKDEGCGIPKEKIPKLNEAFYTTKETGTGLGLVVTEKIIKDHNGKMSFESEVGVGTTVK
VMLPIQ

Specific function: Phosphorylates the sporulation-regulatory protein spo0A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=252, Percent_Identity=26.5873015873016, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=26.457399103139, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1790300, Length=243, Percent_Identity=23.8683127572016, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=23.109243697479, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=26.2548262548263, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994928, Length=109, Percent_Identity=33.0275229357798, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=138, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87081816, Length=134, Percent_Identity=29.1044776119403, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=116, Percent_Identity=31.0344827586207, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46240; Mature: 46240

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure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HEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8002615; 8002614; 8969500; 9384377 [H]