Click here to switch to the map view.

The map label for this gene is accD

Identifier: 49187490

GI number: 49187490

Start: 4410739

End: 4411608

Strand: Reverse

Name: accD

Synonym: BAS4495

Alternate gene names: 49187490

Gene position: 4411608-4410739 (Counterclockwise)

Preceding gene: 49187491

Following gene: 49187489

Centisome position: 84.37

GC content: 40.34

Gene sequence:

>870_bases
GTGCTAAGAGATTTATTCGTGAAAAAGAAAAAGTACGCTGCAATACCTTCAGAACAAGTACGAAAAGATGTACCAGATGG
CGTTATGACAAAATGTCCGAAATGTAAAAAAATCATGTATACGAAAGAAGTTCTAAAAAATTTAAAAGTATGTGTGAATT
GTGGTTATCATCATCCTATGAATGCGTGGGAACGTCTTGATAGTATATTGGACGAAGGGTCATTCCGTGAGTATGACAAA
GAAATGGTTTCATTAAATCCACTCGAGTTTCCAAATTATGAAGAGAAACTAGAGAGCGATCGTAAGAAGACTGAATTGAA
CGAAGCGGTTGTAACTGGTGAAGGAACAATTGATGACATGCTTGTTGTTGTTGCAGTAATGGATTCTCGTTTTCGAATGG
GGAGCATGGGCTCTGTTGTAGGAGAAAAAATTGCCCGTGCGGTTGAAAAGGCATACGACTTACAAGTTCCATTTATTATC
TTTACTGCTTCGGGTGGTGCCCGTATGCAAGAAGGGATATTAAGTTTAATGCAAATGGCAAAAACAAGCGTAGCTTTGAA
AAAGCATAGTAATGCAGGAGGATTATTTATTTCTGTTATGACTCACCCAACGACGGGCGGGGTTTCAGCAAGTTTCGCTT
CACTTGGTGATTATAATCTTGCAGAACCGGGGGCACTGATCGGATTTGCTGGTAGACGTGTAATTGAACAAACCGTGCGT
GAGAAACTACCGGAAGATTTCCAAACGGCAGAATTCTTACTAGAACATGGTCAATTAGATGCGGTAGTACATCGTGATGA
TATGAGAGAATCGCTTCGCAAGATTTTAGAAGTTCATCAAGGAGGGGAAATGGCTGTATGGCAGAGCTAG

Upstream 100 bases:

>100_bases
TTATTAGACAGATTGAGAAGATAAGGCTAACATCAAACTTTGGTGTTAGCCCAATTTTCTTCTTACGCTAACCTTAGCTC
TCAACGAAGGGGGTCAAATT

Downstream 100 bases:

>100_bases
AATTTGAGAAACCAGTTGTTGAGCTAAGAAATAAGATTCGTGAACTGAAAGACTATACGAAAAACAGCCAGATGGACTTC
AGTGAGGAGATTCGTATTTT

Product: acetyl-CoA carboxylase subunit beta

Products: NA

Alternate protein names: ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDK
EMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFII
FTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVR
EKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS

Sequences:

>Translated_289_residues
MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDK
EMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFII
FTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVR
EKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
>Mature_289_residues
MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPMNAWERLDSILDEGSFREYDK
EMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDMLVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFII
FTASGGARMQEGILSLMQMAKTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVR
EKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccD/PCCB family

Homologues:

Organism=Escherichia coli, GI1788655, Length=259, Percent_Identity=52.5096525096525, Blast_Score=258, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI25147362, Length=227, Percent_Identity=28.6343612334802, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCD_BACAA (C3PAJ0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868880.1
- ProteinModelPortal:   C3PAJ0
- SMR:   C3PAJ0
- EnsemblBacteria:   EBBACT00000130163
- GeneID:   7848835
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4857
- GeneTree:   EBGT00050000000002
- ProtClustDB:   PRK05654
- HAMAP:   MF_01395
- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011762
- PRINTS:   PR01070
- TIGRFAMs:   TIGR00515

Pfam domain/function: PF01039 Carboxyl_trans

EC number: =6.4.1.2

Molecular weight: Translated: 32282; Mature: 32282

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50980 COA_CT_NTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPM
CCHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAWERLDSILDEGSFREYDKEMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHH
LVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
>Mature Secondary Structure
MLRDLFVKKKKYAAIPSEQVRKDVPDGVMTKCPKCKKIMYTKEVLKNLKVCVNCGYHHPM
CCHHHHHHHHHHHCCCHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAWERLDSILDEGSFREYDKEMVSLNPLEFPNYEEKLESDRKKTELNEAVVTGEGTIDDM
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHEEECCCCHHHH
LVVVAVMDSRFRMGSMGSVVGEKIARAVEKAYDLQVPFIIFTASGGARMQEGILSLMQMA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHH
KTSVALKKHSNAGGLFISVMTHPTTGGVSASFASLGDYNLAEPGALIGFAGRRVIEQTVR
HHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EKLPEDFQTAEFLLEHGQLDAVVHRDDMRESLRKILEVHQGGEMAVWQS
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA