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The map label for this gene is accA

Identifier: 49187489

GI number: 49187489

Start: 4409777

End: 4410751

Strand: Reverse

Name: accA

Synonym: BAS4494

Alternate gene names: 49187489

Gene position: 4410751-4409777 (Counterclockwise)

Preceding gene: 49187490

Following gene: 49187488

Centisome position: 84.36

GC content: 39.28

Gene sequence:

>975_bases
ATGGCAGAGCTAGAATTTGAGAAACCAGTTGTTGAGCTAAGAAATAAGATTCGTGAACTGAAAGACTATACGAAAAACAG
CCAGATGGACTTCAGTGAGGAGATTCGTATTTTGGAAGACAAGCTAGAAAATTTAGAGGAAGATATATACGGCAATATGA
AAGTATGGGACCGTGTTCAAATTGCTCGTCATGCAGAACGACCGACAACGCTCGATTATATTGAGCACTTATTTACTGAT
TTTTTTGAATGTCATGGAGATCGTCTATTTGGCGATGATGCAGCGATTGTCGGCGGCATTGCGAAATATAAAGGGATGCC
TGTAACTGTAATTGGGCACCAACGCGGAAAAGATACGAAAGAAAATATTCGCCGTAATTTTGGGATGCCTCATCCAGAAG
GATATCGAAAAGCATTGCGTTTAATGAAGCAGGCGGAAAAGTTCAATCGTCCAATTATTTGTTTTATTGATACGAAAGGA
GCTTATCCTGGTAAAGCTGCTGAAGAACGTGGTCAAAGTGAAGCGATCGCCCGCAATTTATTTGAAATGGCAGGCTTAAC
GGTACCTGTTATTTGTATCGTTATCGGCGAAGGTGGTAGCGGTGGTGCGCTAGGTCTTGGAGTAGGAGATTACATTCATA
TGCTAGAAAATTCCACTTATTCTGTTATTACACCAGAGGGTGCAGCGGCAATTCTTTGGAAAGATGCAGGAAAAGCAAAG
GAAGCTGCAGAGGCGATGAGAATTACAGCGGCAGATTTGAAAGAATTAGGTGTAATTGACGAAATTATTCCAGAGGCAAA
AGGTGGAGCACACCGTAATGTTTTGAAACAGTCAGAAAATATAGATTTAATGCTTAGAAAAACTTTTGAACAATTAAACG
GAATTTCGAAAGATGAATTAATCGAAAAACGTTATGAAAAATATATGAAAATTGGGCAAGTTTCGTTTTCAAACGCTTCC
ATTTGGATAAAATAA

Upstream 100 bases:

>100_bases
TACTAGAACATGGTCAATTAGATGCGGTAGTACATCGTGATGATATGAGAGAATCGCTTCGCAAGATTTTAGAAGTTCAT
CAAGGAGGGGAAATGGCTGT

Downstream 100 bases:

>100_bases
GAAAAGCGTGCGTTCCACTTCGCGAATGCACGTTTTTATTATGAAAAGACACATCTTCTCCATTGTATTTTTATATTTTT
TCGTGTTATTTTATTATAAG

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTD
FFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKG
AYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAK
EAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNAS
IWIK

Sequences:

>Translated_324_residues
MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTD
FFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKG
AYPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAK
EAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNAS
IWIK
>Mature_323_residues
AELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQIARHAERPTTLDYIEHLFTDF
FECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTKENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGA
YPGKAAEERGQSEAIARNLFEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAKE
AAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDELIEKRYEKYMKIGQVSFSNASI
WIK

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family

Homologues:

Organism=Escherichia coli, GI1786382, Length=312, Percent_Identity=55.1282051282051, Blast_Score=345, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACCA_BACAA (C3PAI9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868879.1
- ProteinModelPortal:   C3PAI9
- SMR:   C3PAI9
- EnsemblBacteria:   EBBACT00000130477
- GeneID:   7853042
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4856
- GeneTree:   EBGT00050000002181
- ProtClustDB:   PRK05724
- HAMAP:   MF_00823
- InterPro:   IPR001095
- InterPro:   IPR011763
- PANTHER:   PTHR22855:SF3
- PRINTS:   PR01069
- TIGRFAMs:   TIGR00513

Pfam domain/function: PF03255 ACCA

EC number: =6.4.1.2

Molecular weight: Translated: 36470; Mature: 36339

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQ
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTK
HHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCEEEEECCCCCCHH
ENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHHH
FEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAK
HHHHCCCEEEEEEEEECCCCCCEEECCHHHHHHHHCCCCEEEECCCCCEEEEECCCCCHH
EAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHH
IEKRYEKYMKIGQVSFSNASIWIK
HHHHHHHHHHHCCEEECCCEEEEC
>Mature Secondary Structure 
AELEFEKPVVELRNKIRELKDYTKNSQMDFSEEIRILEDKLENLEEDIYGNMKVWDRVQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
IARHAERPTTLDYIEHLFTDFFECHGDRLFGDDAAIVGGIAKYKGMPVTVIGHQRGKDTK
HHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCEEEEECCCCCCHH
ENIRRNFGMPHPEGYRKALRLMKQAEKFNRPIICFIDTKGAYPGKAAEERGQSEAIARNL
HHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHCCHHHHHHHHH
FEMAGLTVPVICIVIGEGGSGGALGLGVGDYIHMLENSTYSVITPEGAAAILWKDAGKAK
HHHHCCCEEEEEEEEECCCCCCEEECCHHHHHHHHCCCCEEEECCCCCEEEEECCCCCHH
EAAEAMRITAADLKELGVIDEIIPEAKGGAHRNVLKQSENIDLMLRKTFEQLNGISKDEL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHH
IEKRYEKYMKIGQVSFSNASIWIK
HHHHHHHHHHHCCEEECCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA