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The map label for this gene is obgE [H]

Identifier: 49187333

GI number: 49187333

Start: 4249597

End: 4250883

Strand: Reverse

Name: obgE [H]

Synonym: BAS4338

Alternate gene names: 49187333

Gene position: 4250883-4249597 (Counterclockwise)

Preceding gene: 49187334

Following gene: 49187332

Centisome position: 81.3

GC content: 42.35

Gene sequence:

>1287_bases
ATGTTTATAGATCAGGTCAAGATATATGTAAAAGGCGGCGACGGTGGTAACGGAATGGTTGCGTATCGTCGTGAGAAGTA
TGTACCAAAAGGTGGCCCAGCAGGTGGCGACGGTGGTAAAGGTGCAGATGTTGTTTTTATTGTTGAGGAAGGCTTACGTA
CATTAATGGACTTCCGCTACCAACGTCATTTCAAAGCTGATCGCGGTCAGCACGGAATGAGTAAAGGTCAGCACGGACGT
AAATCTGAAGATTTACTTGTAAAGGTTCCGCCAGGAACAGTAGTAAAAGATGAAAAAACTGGTCAAATTCTTGCGGATTT
AGTAACGCATGGACAAACGGCTGTAATTGCAAAAGGTGGCCGCGGTGGTCGTGGTAACTCACGTTTCGCAACAGCTACGA
ACCCAGCGCCAGAAATCGCTGAAAACGGGGAACCAGGTCAAGAGCGTGATGTCATTCTAGAACTGAAAGTACTGGCAGAC
GTTGGACTTGTTGGATTCCCAAGTGTAGGTAAATCTACATTATTATCTGTCGTATCATCAGCACGTCCGAAAATTGCAGA
GTATCACTTCACAACAATCGTTCCAAACCTTGGTGTTGTTGAAACTGGTGATAACCGCAGCTTCGTTATGGCTGACCTTC
CTGGACTAATTGAAGGCGCACATGCTGGCGTCGGACTTGGACACCAATTCTTACGTCATATTGAGCGTACACGTGTAATC
GTGCATGTTATTGATATGTCTGGTTTAGAAGGCCGTGATCCATATGAAGATTACGTAACAATTAATAATGAATTAAAAGA
ATACAATCTTCGCTTAACGGAGCGTCCACAAGTTGTTGTTGCAAACAAAATGGATATGCCAGATGCAGAAGAAAACTTAC
AAGCATTTAAAGAGAAAGTGGGAGACGAAGTAAAAATCTTCCCAATCTCAGCTGTAACGAAACAAGGTGTTCGTGACTTA
CTGTTTGAAGTAGCGAACTTAATAGAAACAACACCTGAATTCCCAATACATGAAGTTGTGGATGAGTCTGACACAAGTGT
AATGTACAAATTTGAGACTGAAGGTGTTAAATTTGATATTACACGTGAAAGTGATGGTACGTTTGTTATCTCTGGTTACG
ATATCGAGAAAACATTCAAGATGACAGACTTCTCACGTGATGAATCTGTACGTCGTTTCGCTCGCCAAATGCGCGGAATG
GGTATTGATGAAGCGCTTCGTGCACGTGGTGCAAAAGACGGAGATATTGTAAAAATTCTTGAATATGAATTTGAATTTAT
CGACTAA

Upstream 100 bases:

>100_bases
TTGCGAACCAAAACAATAAATGGTATTCCATTTCTTATACAGTACGAGACGAGGAAGTCTCAGTTATATTACAACCAATT
GAAAAAAGTGTGGTGAAATA

Downstream 100 bases:

>100_bases
GACTGCCGAAATACGGCAGTCTTTTTTTATATCGTAAAAGTCTGATTTATACAGGAAAAAATCCCCACTAATTAAATTTT
CAATTTATAATAGAAAAAGA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFIDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Sequences:

>Translated_428_residues
MFIDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID
>Mature_428_residues
MFIDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRYQRHFKADRGQHGMSKGQHGR
KSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGGRGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=334, Percent_Identity=40.1197604790419, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI111955139, Length=347, Percent_Identity=36.3112391930836, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI111955063, Length=236, Percent_Identity=36.864406779661, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.1085271317829, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4557537, Length=90, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=351, Percent_Identity=46.7236467236467, Blast_Score=301, Evalue=6e-83,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=35.5072463768116, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=38.006230529595, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=31.4102564102564, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=35.5932203389831, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=37.1134020618557, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.8888888888889, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=32.5396825396825, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=40.1294498381877, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI20129375, Length=304, Percent_Identity=40.1315789473684, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21356473, Length=163, Percent_Identity=34.3558282208589, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=34.6456692913386, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47225; Mature: 47225

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC
>Mature Secondary Structure
MFIDQVKIYVKGGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFIVEEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHH
QRHFKADRGQHGMSKGQHGRKSEDLLVKVPPGTVVKDEKTGQILADLVTHGQTAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCEECCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATATNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCEEEECCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLIETTPEFPIHEVVDESDTSVMYKFETEGVKFDI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA