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The map label for this gene is catE [H]

Identifier: 49187252

GI number: 49187252

Start: 4169759

End: 4170199

Strand: Reverse

Name: catE [H]

Synonym: BAS4256

Alternate gene names: 49187252

Gene position: 4170199-4169759 (Counterclockwise)

Preceding gene: 49187253

Following gene: 49187251

Centisome position: 79.76

GC content: 36.51

Gene sequence:

>441_bases
ATGAGTTTTCAACTTCATCCCGATACAACACTTGATGTTGTTCATTTATATGTATCAAATATAAAGAAATCACTAGAGTT
TTATACAGAAGTACTACGTATGAAAGTGCTAAAAGAAGATGAAATGGTCGTTACATTTGGGAATGAAGATAACGAACCAC
TCCTTATCATTGAAGAAAAGAAAGAAGCTTTACCAAAGCAAAGAGGGAGAACAGGTTTATATCATTACGCAATTTTATTA
CCGAGCAGACAGGATTTAGCGAATATCCTTCGTCATTTTGTAGAAATGGTATATCCACTGCACGGCGGAGCTGACCATTA
CTTTAGTGAGGCTCTTTATTTAGCTGATCCAGATGGAAACGGGATTGAAATTTATCATGATCGCCAAAAAAAGTTTGGCG
TGATGAGAATGGAGAGCTACCATTTGTTAGTAACCCGTTAG

Upstream 100 bases:

>100_bases
GGGGGCGTACTTATTTGTTGCGAAAGCGGATGGTTTTGTAGATAATTTCTTAAAAGAGAAAATGTCAAAGAAGAACTAAT
TTAAATGGGAGGCTAACAAG

Downstream 100 bases:

>100_bases
CTGGGGAAGAATTATTGCAGCAAGGAAGTACATGGAATGGTTTTCCATCTGGTACTGTGATGGGACATATTCATTTCCAT
GTAGCTGATTTGGAAGAAGC

Product: glyoxase; glyoxalase/bleomycin resistance protein

Products: NA

Alternate protein names: Catechol-induced ring cleavage extradiol dioxygenase [H]

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSFQLHPDTTLDVVHLYVSNIKKSLEFYTEVLRMKVLKEDEMVVTFGNEDNEPLLIIEEKKEALPKQRGRTGLYHYAILL
PSRQDLANILRHFVEMVYPLHGGADHYFSEALYLADPDGNGIEIYHDRQKKFGVMRMESYHLLVTR

Sequences:

>Translated_146_residues
MSFQLHPDTTLDVVHLYVSNIKKSLEFYTEVLRMKVLKEDEMVVTFGNEDNEPLLIIEEKKEALPKQRGRTGLYHYAILL
PSRQDLANILRHFVEMVYPLHGGADHYFSEALYLADPDGNGIEIYHDRQKKFGVMRMESYHLLVTR
>Mature_145_residues
SFQLHPDTTLDVVHLYVSNIKKSLEFYTEVLRMKVLKEDEMVVTFGNEDNEPLLIIEEKKEALPKQRGRTGLYHYAILLP
SRQDLANILRHFVEMVYPLHGGADHYFSEALYLADPDGNGIEIYHDRQKKFGVMRMESYHLLVTR

Specific function: Involved in the meta cleavage of catechol to 2- hydroxymuconic semialdehyde. Essential for growth and viability in the presence of catechol and probably involved in the detoxification of catechol [H]

COG id: COG2514

COG function: function code R; Predicted ring-cleavage extradiol dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the extradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360
- InterPro:   IPR000486 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: =1.13.11.2 [H]

Molecular weight: Translated: 17082; Mature: 16951

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFQLHPDTTLDVVHLYVSNIKKSLEFYTEVLRMKVLKEDEMVVTFGNEDNEPLLIIEEK
CCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECC
KEALPKQRGRTGLYHYAILLPSRQDLANILRHFVEMVYPLHGGADHYFSEALYLADPDGN
HHCCHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEECCCCC
GIEIYHDRQKKFGVMRMESYHLLVTR
CEEEEECCCHHCCEEEECCEEEEEEC
>Mature Secondary Structure 
SFQLHPDTTLDVVHLYVSNIKKSLEFYTEVLRMKVLKEDEMVVTFGNEDNEPLLIIEEK
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECC
KEALPKQRGRTGLYHYAILLPSRQDLANILRHFVEMVYPLHGGADHYFSEALYLADPDGN
HHCCHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEECCCCC
GIEIYHDRQKKFGVMRMESYHLLVTR
CEEEEECCCHHCCEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8704981; 9384377 [H]