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The map label for this gene is cdd [H]

Identifier: 49187196

GI number: 49187196

Start: 4116130

End: 4116528

Strand: Reverse

Name: cdd [H]

Synonym: BAS4200

Alternate gene names: 49187196

Gene position: 4116528-4116130 (Counterclockwise)

Preceding gene: 49187197

Following gene: 49187195

Centisome position: 78.73

GC content: 37.84

Gene sequence:

>399_bases
ATGAATAGTAAACAATTAATTCAAGAAGCAATCGAAGCGCGTAAACAAGCGTACGTACCATATTCTAAATTTCAAGTAGG
TGCAGCATTATTAACACAGGATGGAAAAGTATATCGTGGATGTAATGTTGAGAATGCATCATATGGTTTATGTAACTGTG
CAGAAAGAACAGCTTTATTTAAGGCGGTTTCTGAAGGAGATAAAGAGTTTGTAGCTATCGCGATTGTAGCGGATACAAAG
CGTCCAGTACCTCCTTGTGGAGCATGTCGACAAGTTATGGTAGAATTATGTAAACAGGATACGAAAGTATACCTATCAAA
TTTACATGGTGACGTTCAAGAGACAACAGTCGGAGAATTGTTACCAGGAGCATTTTTAGCGGAGGATTTACATGAATAG

Upstream 100 bases:

>100_bases
GTTGCATTCCAAAGCTTTTATTAAGCTTTGAAGGTGCTGTAAAGGCCTTTAATAAGAGAGTGTATCTATTCACAGCTGTG
AACAGGAAGGATGCGGGAAT

Downstream 100 bases:

>100_bases
AAAAGGTTATAAATCAGGTTTTGTCTCTATTATTGGCAGACCGAATGTTGGGAAATCTACATTTTTAAATCGTATTATTG
GTCAAAAAATTGCTATTATG

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 132; Mature: 132

Protein sequence:

>132_residues
MNSKQLIQEAIEARKQAYVPYSKFQVGAALLTQDGKVYRGCNVENASYGLCNCAERTALFKAVSEGDKEFVAIAIVADTK
RPVPPCGACRQVMVELCKQDTKVYLSNLHGDVQETTVGELLPGAFLAEDLHE

Sequences:

>Translated_132_residues
MNSKQLIQEAIEARKQAYVPYSKFQVGAALLTQDGKVYRGCNVENASYGLCNCAERTALFKAVSEGDKEFVAIAIVADTK
RPVPPCGACRQVMVELCKQDTKVYLSNLHGDVQETTVGELLPGAFLAEDLHE
>Mature_132_residues
MNSKQLIQEAIEARKQAYVPYSKFQVGAALLTQDGKVYRGCNVENASYGLCNCAERTALFKAVSEGDKEFVAIAIVADTK
RPVPPCGACRQVMVELCKQDTKVYLSNLHGDVQETTVGELLPGAFLAEDLHE

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=130, Percent_Identity=53.8461538461538, Blast_Score=130, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17540514, Length=127, Percent_Identity=48.8188976377953, Blast_Score=114, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=45.3125, Blast_Score=108, Evalue=9e-25,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=37.984496124031, Blast_Score=89, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582741, Length=127, Percent_Identity=50.3937007874016, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24582744, Length=117, Percent_Identity=41.8803418803419, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI19920920, Length=138, Percent_Identity=42.0289855072464, Blast_Score=102, Evalue=6e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14426; Mature: 14426

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKQLIQEAIEARKQAYVPYSKFQVGAALLTQDGKVYRGCNVENASYGLCNCAERTALF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHH
KAVSEGDKEFVAIAIVADTKRPVPPCGACRQVMVELCKQDTKVYLSNLHGDVQETTVGEL
HHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LPGAFLAEDLHE
CCHHHHHHHHCC
>Mature Secondary Structure
MNSKQLIQEAIEARKQAYVPYSKFQVGAALLTQDGKVYRGCNVENASYGLCNCAERTALF
CCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHH
KAVSEGDKEFVAIAIVADTKRPVPPCGACRQVMVELCKQDTKVYLSNLHGDVQETTVGEL
HHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
LPGAFLAEDLHE
CCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]