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The map label for this gene is buk

Identifier: 49187067

GI number: 49187067

Start: 4000621

End: 4001724

Strand: Reverse

Name: buk

Synonym: BAS4069

Alternate gene names: 49187067

Gene position: 4001724-4000621 (Counterclockwise)

Preceding gene: 49187068

Following gene: 49187066

Centisome position: 76.53

GC content: 37.95

Gene sequence:

>1104_bases
GTGTCTGTAAATCGAATTCTTGTTATTAATCCGGGTAGTACATCCACAAAAATTGGTGTTTTTGATAATGAAAGACCCGT
TTTAGAAGAAACTATTCGTCATGATGAAGAACAGATTGGAAAATATAAGCGAATTATCGACCAATATGAGTTTCGTAAAG
AAACGATCTTAGAAGTTCTACATTCTCACGGTATTAACATTTCAAAATTAAACGCAGTTTGTGGACGCGGGGGATTACTT
CGTCCAATCGAAGGCGGAACATACACAGTAAACGATGCGATGTTAGAAGATTTAAAAAATGGTTTTAGTGGTCATCACGC
TTCAAACCTTGGGGGCATTTTAGCATATGAAATAGCTTCTGGATTAAATATTCCGGCATTCATTGTAGATCCTGTCGTTG
TAGATGAAATGGAGCCGATTGCTCGTATAAGTGGTATTGCTGGTATGGAACGTAAAAGTATTTTCCATGCATTAAATCAA
AAAGCAGTTGCTCGTAAAGTAGCTGAAGAATTAAACCACAAATATGAGGATTTAAATTTATTAGTTACACATATGGGCGG
CGGTATTACAGTTGGTGCTCATAAAAAAGGAAAAGTTATCGATGTGAATAATGGCTTAAACGGAGAAGGACCATTTAGCC
CAGAGCGTGCTGGTACAGTACCAGTAGGACAACTAGTTGAAATGTGTTTCTCTGGTGAGTATTACCGAGATGAAATGGTT
AAAAAACTTGTCGGACAAGGTGGACTTGTAAGTCTTATCGGTACAAATGATGCGATTAAAGTAGAACAAATGGTTGAAAA
AGGTGATCCTGAAGCAACTCTTATTTATAAGGCAATGGCATATCAAGTTGCAAAAGAGATTGGCGGAGCTAGCGCTGTAC
TTCACGGGAAAATCGATGCAATCGTATTAACTGGTGGACTTGCTTATAGTAAAATTCTTGTTGATGAAATAAAAGAACGA
GTAGACTGGATTGCAGATGTTATCGTACATCCAGGAGAAGATGAATTACAAGCATTAGCAGAAGGGGCACTTCGTGTACT
ACGTGAAGAAGAAGCTCCAAAAGAATATATTGTACGTGAAAAAGAAACGGTAGCTAGGGGTTGA

Upstream 100 bases:

>100_bases
TAGCCGTCGCTAATCATTCATATATTACTTTTACAAAAGGTGTGGTTACCTCTTATGAGGTTTCCACCTCCTTTTGAATT
TATTAGTGGAGGTAGCAACA

Downstream 100 bases:

>100_bases
GATAATGGCAAAAGAATATGATTTAGTCATCGTTGGCGGCGGTACTGGCGGATATGTTGCTGCAATTCGTGCATCACAAC
TAGGTTTAAAAACTGCACTT

Product: butyrate kinase

Products: NA

Alternate protein names: BK; Branched-chain carboxylic acid kinase

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLL
RPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQ
KAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMV
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKER
VDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Sequences:

>Translated_367_residues
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLL
RPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQ
KAVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMV
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKER
VDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG
>Mature_366_residues
SVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVLHSHGINISKLNAVCGRGGLLR
PIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIASGLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQK
AVARKVAEELNHKYEDLNLLVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMVK
KLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDAIVLTGGLAYSKILVDEIKERV
DWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVREKETVARG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG3426

COG function: function code C; Butyrate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=222, Percent_Identity=24.7747747747748, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788633, Length=170, Percent_Identity=28.2352941176471, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BUK_BACAA (C3P7U3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868458.1
- ProteinModelPortal:   C3P7U3
- SMR:   C3P7U3
- EnsemblBacteria:   EBBACT00000128315
- GeneID:   7852869
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4405
- GeneTree:   EBGT00050000000769
- ProtClustDB:   PRK03011
- GO:   GO:0005737
- HAMAP:   MF_00542
- InterPro:   IPR000890
- InterPro:   IPR011245
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF3
- PIRSF:   PIRSF036458
- PRINTS:   PR00471
- TIGRFAMs:   TIGR02707

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.7

Molecular weight: Translated: 39969; Mature: 39838

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVL
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIAS
HHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNL
CCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
LVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMV
EEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDA
HHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVRE
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
KETVARG
HHHHCCC
>Mature Secondary Structure 
SVNRILVINPGSTSTKIGVFDNERPVLEETIRHDEEQIGKYKRIIDQYEFRKETILEVL
CCCEEEEECCCCCCCEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
HSHGINISKLNAVCGRGGLLRPIEGGTYTVNDAMLEDLKNGFSGHHASNLGGILAYEIAS
HHCCCCHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCHHHHHHHC
GLNIPAFIVDPVVVDEMEPIARISGIAGMERKSIFHALNQKAVARKVAEELNHKYEDLNL
CCCCCHHEECCHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHE
LVTHMGGGITVGAHKKGKVIDVNNGLNGEGPFSPERAGTVPVGQLVEMCFSGEYYRDEMV
EEEECCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
KKLVGQGGLVSLIGTNDAIKVEQMVEKGDPEATLIYKAMAYQVAKEIGGASAVLHGKIDA
HHHHCCCCEEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEE
IVLTGGLAYSKILVDEIKERVDWIADVIVHPGEDELQALAEGALRVLREEEAPKEYIVRE
EEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHCC
KETVARG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA