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The map label for this gene is yqkF [H]

Identifier: 49187003

GI number: 49187003

Start: 3943400

End: 3944314

Strand: Direct

Name: yqkF [H]

Synonym: BAS4005

Alternate gene names: 49187003

Gene position: 3943400-3944314 (Clockwise)

Preceding gene: 49187001

Following gene: 49187007

Centisome position: 75.42

GC content: 35.96

Gene sequence:

>915_bases
ATGAAAAAACGTCAATTAGGAAACTCAGATTTATTTGTGACAGAAATGGGACTTGGCTGTATGTCTCTCGGTACATCTGA
AGCAGAAGCTATGCGTATTATCGACGAAGCAATCGATTTAGGAATCAATTTTTTTGATACAGCAGATTTATATGATTATG
GATTAAACGAAGAATTTGTTGGAAAAGCATTAAAAGGGAAACGAGATCAAATTGTTCTTACAACGAAGGTTGGAAATCGA
TGGACAGAAGAAAAAAACGGCTGGTCTTGGGATCCTTCTAAAAATTACATAAAAGCTGAAGTGAAAGAAAGTTTACGTAG
ACTTCAAACCGATTATATTGATTTATATCAACTTCATGGCGGGACGATTGAAGATCCTATAGATGAAACAATTGAAGCCT
TTGAAGAATTAAAAAAAGAAGGTATCATTCGCCATTACGGTATTTCTTCTATACGTCCAAATGTCATCCGTGAGTATGCA
AAACGTTCAAATATCGTCAGTGTACTAATGGAATATAGCCTTTTAAATCGTCGCCCTGAAGAATGGTTCCCGCTTCTTAA
TGAACATCAAATTAGCGTCATTGCCCGCGGACCGCTTGCAAAAGGAATTCTAACTGACAACAATGCAAGAAAGATAGAAA
GAGTAAAAGAAAAGGATTACCTTTCTTATTCTTACGATGAATTATATGGGACACTCGCGAATGTAAAAGAATTAATCGTG
GAAAGTTCTTTAACAGGAACAGCTATTCAATATTGCTTACATAACGACACTGTAGCAGCTGTAATACCTGGTGCAAGCTC
TATTCAACAATTACGAGAAAATGTACAAGCCTGTAAGCAAACACAGTTAACAACAGAAGAATATATACAGCTTCAGCAAA
TCGCTAAATGTGATACGTACGCTTTACATCGTTAA

Upstream 100 bases:

>100_bases
AAGAGTATACAACTGTACAAGAGTGGATTACAGCTAGTAAAAAGTAAAAGTTTGTCAACCTCTTTTCCCTTTCGTACAAT
AAGAGTAAGGAGGTTGACTT

Downstream 100 bases:

>100_bases
AAAGACGCTACCATACTGGTAGCGTCTTTTTATAACGTATCATATTTATCAGGATTCGTTCCTACATGTAAATTACGATT
TAACGTATTAATTTCAGTCA

Product: lolS protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSEAEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIVLTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYGTLANVKELIV
ESSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQACKQTQLTTEEYIQLQQIAKCDTYALHR

Sequences:

>Translated_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSEAEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIVLTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYGTLANVKELIV
ESSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQACKQTQLTTEEYIQLQQIAKCDTYALHR
>Mature_304_residues
MKKRQLGNSDLFVTEMGLGCMSLGTSEAEAMRIIDEAIDLGINFFDTADLYDYGLNEEFVGKALKGKRDQIVLTTKVGNR
WTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHGGTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYA
KRSNIVSVLMEYSLLNRRPEEWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYGTLANVKELIV
ESSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQACKQTQLTTEEYIQLQQIAKCDTYALHR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=308, Percent_Identity=30.1948051948052, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI4504825, Length=305, Percent_Identity=30.1639344262295, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436964, Length=306, Percent_Identity=29.7385620915033, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI27436966, Length=306, Percent_Identity=29.4117647058824, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI27436962, Length=306, Percent_Identity=29.4117647058824, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI27436971, Length=321, Percent_Identity=27.7258566978193, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI223718702, Length=300, Percent_Identity=26.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=32.5227963525836, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788070, Length=306, Percent_Identity=31.6993464052288, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1789375, Length=324, Percent_Identity=28.3950617283951, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=25.8720930232558, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787674, Length=300, Percent_Identity=25.3333333333333, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788081, Length=295, Percent_Identity=27.1186440677966, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87082198, Length=215, Percent_Identity=28.8372093023256, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=296, Percent_Identity=22.972972972973, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786400, Length=200, Percent_Identity=31, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI212645785, Length=302, Percent_Identity=25.4966887417219, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=27.299703264095, Blast_Score=89, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.3378378378378, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24646155, Length=219, Percent_Identity=30.5936073059361, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=28.9592760180996, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=25.4437869822485, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45549126, Length=338, Percent_Identity=25.4437869822485, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34712; Mature: 34712

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSEAEAMRIIDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKALKGKRDQIVLTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYGTLANVKELIV
HHHCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQACKQTQLTTEEYIQLQQIAKCDTY
HCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALHR
HCCC
>Mature Secondary Structure
MKKRQLGNSDLFVTEMGLGCMSLGTSEAEAMRIIDEAIDLGINFFDTADLYDYGLNEEFV
CCCCCCCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHH
GKALKGKRDQIVLTTKVGNRWTEEKNGWSWDPSKNYIKAEVKESLRRLQTDYIDLYQLHG
HHHHCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
GTIEDPIDETIEAFEELKKEGIIRHYGISSIRPNVIREYAKRSNIVSVLMEYSLLNRRPE
CCCCCHHHHHHHHHHHHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EWFPLLNEHQISVIARGPLAKGILTDNNARKIERVKEKDYLSYSYDELYGTLANVKELIV
HHHCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ESSLTGTAIQYCLHNDTVAAVIPGASSIQQLRENVQACKQTQLTTEEYIQLQQIAKCDTY
HCCCCHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
ALHR
HCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]