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The map label for this gene is dppE [H]

Identifier: 49184745

GI number: 49184745

Start: 1751851

End: 1753410

Strand: Direct

Name: dppE [H]

Synonym: BAS1732

Alternate gene names: 49184745

Gene position: 1751851-1753410 (Clockwise)

Preceding gene: 49184742

Following gene: 49184746

Centisome position: 33.5

GC content: 33.65

Gene sequence:

>1560_bases
ATGAAGCGGAAAAAGAGCCATTTAATGGTAATGGCACTTGTTATATCTTTATTGTTAACAGCTTGTAATAATAAGGAAAA
TAAAAGTGATGCAAAGTCAAAAAAACAAGTATTAAATGTAACAGTATCAGAAGAGATTCCTTCTCTTGATACCGCGAAAA
CGATGGATGGTACGTCAGCGCACGTTATGCAAAACATATTTGAAGGGTTGTATGTATTAGATGATCAAGATCAGCCGATT
CCAGCGGTAGCAAAATCGTTTAAAAGAAGTGAAGATGGTAAAAAATATACATTTGATTTGCGTAAATACGCAAAATGGTC
AAATGGTGACAAGGTGACAGCTCATGATTTTATGTTTGCGTGGAAACGTGCAATTGCTCCTGAAACAGCGTCTCAATATG
CGTCCATGCTCTTTTATGTGAAAAATGCGAAAGAGATTAATAAGGGGACGATGCCTCTTGATGAACTTGGGGTTACGGTT
ATAAATGATTATAAGTTAGAGGTGGAACTAGAACAGCCAATTCCTTATTTTTTACAGTTGTTAGCACTACCTATATACCT
ACCACAGCATGAATCATTTTTGAAAGAACAAGGAAAGAACTATGCATTGGAACCTAGTAATCTCCTATATAACGGTCCAT
TTATATTAGAGAAATGGAAGCATGAACAAGAGTTTCAATTAAAGAAGAATGCTACCTATTGGGATCAAAAGAAAGTGAAA
TTAGATGAAATAAACTTTCAAATTGTAAAGGATACAATGACGGCTGTTAATTTATACGAAGCTGGTAATTTGGATAGGGT
ACCTATTAATTCTCAATTTGTAGACAAGTATAAAGGGAATAAGGAATTACATATGTCGAGTGATTCTGGAATTGCTATGC
TACGTTTTAATGAAAAAAATAATGCATTAGCAAATAAAAAGGTACGTCAATCTATTTCTTTAGCGTTAAATAAAGAGGAC
TTCGTTACTCACTTTATTAATAACGGAGCAAAACCTGCCAGTGGATTAGTACCAGCTGGTCATATAAATGAAGAGACTGG
TAAAGATTTTAGAAAAGAAAACGGAAATCTTTCTTCATATGATTTGCAAAATGCGAAAAAGATTTGGAAAGAAGCGAAAA
AAGAGCTTGGGGTAGAACAAGTAAACCTCGAGTTATTAACGTTTGAACAAGATAATGCAAAACGTATGGCAGAATATATA
AAAGGTGATTTAGAAAAGAATTTACAAGGACTAACGATACAAATTAAACAACAGCCATTTAAGCAAAAATTACAGTTAGA
ACAAACAGGTAATTACGATATAACTATGGCAAATTGGGGACCTGACTATAAAGACCCAATTAGTTATTTAGAATTATTTA
CGACAGGTAATCCGAATAATAAAATGAATTACTCTAATTCTCGTTATGATGAATTAATAAAGAAAGCGAAAACTGATTTT
GTACTAGAACCAGAGAAACGATGGGAAGCATTGCTAGAAGCTGAGCAGGTATTATTAGAAGATGCCGCTGTATCATATTG
GTTCAGCATATGTACAAAAGGATTACGTAAAGGGAATTGA

Upstream 100 bases:

>100_bases
TGAACGAATAAATATTCAAAAGAATGTCGCATCTTTCTGGTAGTATTTCTGCTATAATATATAACGTTTTATAATATTAT
ATTTTTAAGGAGAACAACTT

Downstream 100 bases:

>100_bases
AAAGCATCAATTTGGTGGTGTTTATACTTATAAAAATGCTTATATCGCTAATAAATAAATATAAAAAACCTTACTTATTA
AAAGTAAGGTTTTTTTACAG

Product: oligopeptide ABC transporter solute binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MKRKKSHLMVMALVISLLLTACNNKENKSDAKSKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKYAKWSNGDKVTAHDFMFAWKRAIAPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVTHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGNYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVSYWFSICTKGLRKGN

Sequences:

>Translated_519_residues
MKRKKSHLMVMALVISLLLTACNNKENKSDAKSKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKYAKWSNGDKVTAHDFMFAWKRAIAPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVTHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGNYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVSYWFSICTKGLRKGN
>Mature_519_residues
MKRKKSHLMVMALVISLLLTACNNKENKSDAKSKKQVLNVTVSEEIPSLDTAKTMDGTSAHVMQNIFEGLYVLDDQDQPI
PAVAKSFKRSEDGKKYTFDLRKYAKWSNGDKVTAHDFMFAWKRAIAPETASQYASMLFYVKNAKEINKGTMPLDELGVTV
INDYKLEVELEQPIPYFLQLLALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKNNALANKKVRQSISLALNKED
FVTHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSYDLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYI
KGDLEKNLQGLTIQIKQQPFKQKLQLEQTGNYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
VLEPEKRWEALLEAEQVLLEDAAVSYWFSICTKGLRKGN

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=483, Percent_Identity=29.1925465838509, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87081878, Length=515, Percent_Identity=27.1844660194175, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1789397, Length=500, Percent_Identity=26.2, Blast_Score=185, Evalue=6e-48,
Organism=Escherichia coli, GI1789966, Length=448, Percent_Identity=26.5625, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1787052, Length=420, Percent_Identity=25.2380952380952, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1787762, Length=528, Percent_Identity=22.9166666666667, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787551, Length=536, Percent_Identity=19.9626865671642, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789887, Length=409, Percent_Identity=23.4718826405868, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59496; Mature: 59496

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKKSHLMVMALVISLLLTACNNKENKSDAKSKKQVLNVTVSEEIPSLDTAKTMDGTSA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEEHHCCCCCCCCCCCCCCHH
HVMQNIFEGLYVLDDQDQPIPAVAKSFKRSEDGKKYTFDLRKYAKWSNGDKVTAHDFMFA
HHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCEEEHHHHHHH
WKRAIAPETASQYASMLFYVKNAKEINKGTMPLDELGVTVINDYKLEVELEQPIPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCCEEEECEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
HHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHCCCCCCCCCCCE
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKN
EECCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKEDFVTHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSY
CCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHH
DLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYIKGDLEKNLQGLTIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
KQKLQLEQTGNYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCC
VLEPEKRWEALLEAEQVLLEDAAVSYWFSICTKGLRKGN
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKRKKSHLMVMALVISLLLTACNNKENKSDAKSKKQVLNVTVSEEIPSLDTAKTMDGTSA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHEEEEEHHCCCCCCCCCCCCCCHH
HVMQNIFEGLYVLDDQDQPIPAVAKSFKRSEDGKKYTFDLRKYAKWSNGDKVTAHDFMFA
HHHHHHHCCEEEECCCCCCHHHHHHHHHCCCCCCEEEEHHHHHHCCCCCCEEEHHHHHHH
WKRAIAPETASQYASMLFYVKNAKEINKGTMPLDELGVTVINDYKLEVELEQPIPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHCCCEEEECEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGKNYALEPSNLLYNGPFILEKWKHEQEFQLKKNATYWDQKKVK
HHHHHCCCCHHHHHHHCCCCCCCCCCCEEECCCCHHHHHCCCHHHHHHCCCCCCCCCCCE
LDEINFQIVKDTMTAVNLYEAGNLDRVPINSQFVDKYKGNKELHMSSDSGIAMLRFNEKN
EECCCEEEEEHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKEDFVTHFINNGAKPASGLVPAGHINEETGKDFRKENGNLSSY
CCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHH
DLQNAKKIWKEAKKELGVEQVNLELLTFEQDNAKRMAEYIKGDLEKNLQGLTIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCH
KQKLQLEQTGNYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNSRYDELIKKAKTDF
HHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCCC
VLEPEKRWEALLEAEQVLLEDAAVSYWFSICTKGLRKGN
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]