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The map label for this gene is resE [H]

Identifier: 49183579

GI number: 49183579

Start: 593802

End: 595265

Strand: Reverse

Name: resE [H]

Synonym: BAS0553

Alternate gene names: 49183579

Gene position: 595265-593802 (Counterclockwise)

Preceding gene: 49183580

Following gene: 49183578

Centisome position: 11.38

GC content: 33.2

Gene sequence:

>1464_bases
ATGAGTAAACTTTCACTTAAAATCGGGACATACTTTTTAATATTAGCTTTATGCATTGAAACAATTGCTTTCGTATCTTT
TTACAAAAGTATTTCCAAAATGCGCATTGAAGAGGAAACACTCGCTCTTTTAGAAAAAGGTAATCGCTATAGTAACAAAA
TTACAAGACGTGCTAAGTGGAGTGCACATGCTCAAGAAAAGAAAAACATCGAACGCACTGAATACAATAAAAATCCTAAT
CGTCCTATATACCCAGATTTCGATATCGCGGATGAGGCTGAACACTTAGTTGAATCAGAATCAATTTCTAACTCTGACAT
AGCAATCATTATAACGGACAATAATGGAAAAATCATTTCCACTTCAGAACCCGTAACAAAGGCGATGCAAAAGCAACTTA
CTTGTAAAACAGAACCTATCCCCAAAGACGGATTAATTGTCGAAAAGAACTGGAAAAAATCAAAATTCATTACAACGGTA
AGCCCAATTCACACAACAGAGTTTCAAGGAAAGTTATATATGTTATTAAAAACATCTTTCTTAGAAAACATGTTACTTAA
ACTCATGAAGCAATTTCTTATTATTAGTGTTTTGACGATTATTTTAACGACTATTTCTGTCTTTATTTTTTCTCGTGTCA
TTACAGAACCACTTATCAAAATGAAGAGGGCAACAGAAAAAATGTCAAAATTAAATAAGCCAATTCAATTGGGTATTAAA
CGGAATGATGAACTTGGAAGCTTAGCAAAAACGATTGAGGATTTATCCAGTGAACTGACTTATATGAAAAAAGAAAGAGG
TGAGTTTCTCGCTAGTGTTGCTCATGAATTATTAACTCCATTAACCTATATGAAAGGTTATGCGAAAGTGGCAAAGAGAG
ACTCTTTAACGAAAGAAGAGCGTGAAGAATACTTGCAAATCATCGAGGATGAAACAGATAGTGTAACCGATCTCGTCCAA
GATTTATTTATGCTGGTGCAATTAGAACAACACCAGTTTGTTATAAAAAAACAAAAAGTACTTCTTAGACCATTTTTAGA
ACGAATGGTTGAAAAAACAAAAACAACATTAACAAATAAACAAATGCAACTTCATGTATATTGCAAAGATGATTTAGAAG
TTTGCATAGACGAAAGACGTATGGAACAAGTTATGTTAAATTTATTACACAATGCTTATCAACACTCACTAGAAAACACT
ACTATTACGATACGCGTACTCGCAGAAACAAATTCTTTTACAATAAGTGTACAAGATGAAGGAGAAGGTATTCCTGAAGG
AGATATTCCGCATATTTTTGATCGTTTTTATCGTGTTGATAAATCCAGAACAAGAGCTACTGGAGGAAAAGGTATCGGGC
TAGCTGTTGCTAAAGAAATTGTAGAATTGCATAACGGTTCCATTCTAGTAACAAGCAAATTAGACGTAGGAACAAACTTT
ATAATCGAGCTACCTTTTGAATAA

Upstream 100 bases:

>100_bases
TTTATAAGGTCGGATATAAATGGAAAAGTGAATAATCACTTCGGTCAGTGGAAACTAGTATACCACTGACCCTTTATTAT
GAATAAGGTATGGTGAGAAA

Downstream 100 bases:

>100_bases
TATGTGTGTGAAAACACCAGTAGTAGTAAAAACTACTGGTGTTATTTTGTTCATAAAATTAGCTTATATAAGCTAAGCTT
TTGAAATTATTCTTATTTCA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 487; Mature: 486

Protein sequence:

>487_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSISKMRIEEETLALLEKGNRYSNKITRRAKWSAHAQEKKNIERTEYNKNPN
RPIYPDFDIADEAEHLVESESISNSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTEPIPKDGLIVEKNWKKSKFITTV
SPIHTTEFQGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
RNDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQ
DLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSLENT
TITIRVLAETNSFTISVQDEGEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNF
IIELPFE

Sequences:

>Translated_487_residues
MSKLSLKIGTYFLILALCIETIAFVSFYKSISKMRIEEETLALLEKGNRYSNKITRRAKWSAHAQEKKNIERTEYNKNPN
RPIYPDFDIADEAEHLVESESISNSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTEPIPKDGLIVEKNWKKSKFITTV
SPIHTTEFQGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
RNDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQ
DLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSLENT
TITIRVLAETNSFTISVQDEGEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNF
IIELPFE
>Mature_486_residues
SKLSLKIGTYFLILALCIETIAFVSFYKSISKMRIEEETLALLEKGNRYSNKITRRAKWSAHAQEKKNIERTEYNKNPNR
PIYPDFDIADEAEHLVESESISNSDIAIIITDNNGKIISTSEPVTKAMQKQLTCKTEPIPKDGLIVEKNWKKSKFITTVS
PIHTTEFQGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIKR
NDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEEREEYLQIIEDETDSVTDLVQD
LFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSLENTT
ITIRVLAETNSFTISVQDEGEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNFI
IELPFE

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=33.6244541484716, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=28.9855072463768, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786783, Length=343, Percent_Identity=25.6559766763848, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=24.4813278008299, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=29.7071129707113, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30.4545454545455, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787894, Length=334, Percent_Identity=22.7544910179641, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081816, Length=250, Percent_Identity=25.6, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786912, Length=237, Percent_Identity=28.6919831223629, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788549, Length=222, Percent_Identity=29.2792792792793, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790861, Length=278, Percent_Identity=28.0575539568345, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87082128, Length=302, Percent_Identity=25.8278145695364, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1790346, Length=301, Percent_Identity=23.5880398671096, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=27.5555555555556, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788279, Length=294, Percent_Identity=24.1496598639456, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=23.0434782608696, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=25.4295532646048, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790300, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787374, Length=315, Percent_Identity=21.9047619047619, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55898; Mature: 55767

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKLSLKIGTYFLILALCIETIAFVSFYKSISKMRIEEETLALLEKGNRYSNKITRRAKW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAHAQEKKNIERTEYNKNPNRPIYPDFDIADEAEHLVESESISNSDIAIIITDNNGKIIS
HHHHHHHHCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEE
TSEPVTKAMQKQLTCKTEPIPKDGLIVEKNWKKSKFITTVSPIHTTEFQGKLYMLLKTSF
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCEECCCCCCEEHHHHHHH
LENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
RNDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSLENTTITIRVLAETNSFTISVQDE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEECC
GEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNF
CCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCE
IIELPFE
EEECCCC
>Mature Secondary Structure 
SKLSLKIGTYFLILALCIETIAFVSFYKSISKMRIEEETLALLEKGNRYSNKITRRAKW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SAHAQEKKNIERTEYNKNPNRPIYPDFDIADEAEHLVESESISNSDIAIIITDNNGKIIS
HHHHHHHHCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEE
TSEPVTKAMQKQLTCKTEPIPKDGLIVEKNWKKSKFITTVSPIHTTEFQGKLYMLLKTSF
CCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCEEEEECCCEECCCCCCEEHHHHHHH
LENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCC
RNDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKRDSLTKEE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
REEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QMQLHVYCKDDLEVCIDERRMEQVMLNLLHNAYQHSLENTTITIRVLAETNSFTISVQDE
EEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCEEEEEEECC
GEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNF
CCCCCCCCCCHHHHHHHHHCCHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCE
IIELPFE
EEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]