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The map label for this gene is arlR [H]

Identifier: 49183580

GI number: 49183580

Start: 595331

End: 596002

Strand: Reverse

Name: arlR [H]

Synonym: BAS0554

Alternate gene names: 49183580

Gene position: 596002-595331 (Counterclockwise)

Preceding gene: 49183581

Following gene: 49183579

Centisome position: 11.4

GC content: 33.78

Gene sequence:

>672_bases
ATGGTAAAAATTTTATTAGTAGACGATGAAGAACGTATGTTACGATTATTAGATCTGTTCTTAAGCCCTCGCGGCTATTT
TTGTATGAAAGCTACCTCTGGCCTTGAAGCACTAAAATTAATAGAACAAAAAGACTTCGATATTATTTTGTTAGATGTTA
TGATGCCGAATATGGATGGATGGGATACTTGCTATCAAATTCGGCAAATCTCCAACGTTCCAATTATAATGCTAACAGCT
CGTAATCAAAATTACGATATGGTGAAAGGTCTTACTATGGGCGCAGATGACTATATTACAAAACCATTTGATGAACATGT
ATTAGTCGCAAGAATCGAGGCTATATTACGTCGTACAAAGAAAGATGGATTTGTCAGCTTCAATGGTATTGAGTGGGATA
AAACGAAACATACTGTCACAGTTTATGATGAGAAAATCTCACTAACACCTATCGAGTTTTCGTTACTTAGACTATTTTTA
CAAAATACAAACCGTGCTTATAGCCGAGATGATTTAATCGAGAAAATTTGGGGCTATGAAACAGATATTGAATATAGAAC
AATCGATTCACATATTCGTAATATCCGCGATAAATTACGGAAAAAAGGATTTCCAGTTGAAAATTACTTAGAAACTGTTT
ATAAGGTCGGATATAAATGGAAAAGTGAATAA

Upstream 100 bases:

>100_bases
AGCGAAAAATAACTCCTCCACTCAATCACATAAAAAGAGTTTTTTATTATTTTCATGTAAACTATACAAGTAGAATGAAC
AGTTTGGGGTGCACAAGATT

Downstream 100 bases:

>100_bases
TCACTTCGGTCAGTGGAAACTAGTATACCACTGACCCTTTATTATGAATAAGGTATGGTGAGAAAATGAGTAAACTTTCA
CTTAAAATCGGGACATACTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLRLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPVENYLETVYKVGYKWKSE

Sequences:

>Translated_223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLRLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPVENYLETVYKVGYKWKSE
>Mature_223_residues
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDGWDTCYQIRQISNVPIIMLTA
RNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTKKDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLRLFL
QNTNRAYSRDDLIEKIWGYETDIEYRTIDSHIRNIRDKLRKKGFPVENYLETVYKVGYKWKSE

Specific function: Member of the two-component regulatory system ArlS/ArlR involved in the regulation of adhesion, autolysis, multidrug resistance and virulence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=34.9557522123894, Blast_Score=146, Evalue=8e-37,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=34.6666666666667, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=34.5454545454545, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=32.3008849557522, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790860, Length=202, Percent_Identity=32.1782178217822, Blast_Score=121, Evalue=3e-29,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=36.5217391304348, Blast_Score=120, Evalue=5e-29,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=32.1266968325792, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=30, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=30.3571428571429, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=31.5789473684211, Blast_Score=110, Evalue=5e-26,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=31.8181818181818, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787229, Length=206, Percent_Identity=31.0679611650485, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=28.1818181818182, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI145693140, Length=233, Percent_Identity=27.0386266094421, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1790437, Length=119, Percent_Identity=35.2941176470588, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=35.9223300970874, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693157, Length=120, Percent_Identity=35, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790299, Length=111, Percent_Identity=34.2342342342342, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1789149, Length=128, Percent_Identity=31.25, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1788905, Length=119, Percent_Identity=32.7731092436975, Blast_Score=61, Evalue=5e-11,
Organism=Escherichia coli, GI1788713, Length=108, Percent_Identity=37.037037037037, Blast_Score=61, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=112, Percent_Identity=33.0357142857143, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26355; Mature: 26355

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDG
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
WDTCYQIRQISNVPIIMLTARNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTK
HHHHHHHHHHCCCCEEEEEECCCCCHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLRLFLQNTNRAYSRDDLIEKIWGYE
CCCCEEECCCEECCCCCEEEEEECEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
TDIEYRTIDSHIRNIRDKLRKKGFPVENYLETVYKVGYKWKSE
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCC
>Mature Secondary Structure
MVKILLVDDEERMLRLLDLFLSPRGYFCMKATSGLEALKLIEQKDFDIILLDVMMPNMDG
CEEEEEECCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCCC
WDTCYQIRQISNVPIIMLTARNQNYDMVKGLTMGADDYITKPFDEHVLVARIEAILRRTK
HHHHHHHHHHCCCCEEEEEECCCCCHHHHCEECCCCCCCCCCCCHHHHHHHHHHHHHHHC
KDGFVSFNGIEWDKTKHTVTVYDEKISLTPIEFSLLRLFLQNTNRAYSRDDLIEKIWGYE
CCCCEEECCCEECCCCCEEEEEECEEEECHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCC
TDIEYRTIDSHIRNIRDKLRKKGFPVENYLETVYKVGYKWKSE
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA