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The map label for this gene is tlpC [H]

Identifier: 49183383

GI number: 49183383

Start: 380608

End: 382332

Strand: Reverse

Name: tlpC [H]

Synonym: BAS0355

Alternate gene names: 49183383

Gene position: 382332-380608 (Counterclockwise)

Preceding gene: 49183389

Following gene: 49183382

Centisome position: 7.31

GC content: 31.07

Gene sequence:

>1725_bases
ATGTTAAAAATTCTATATCTGTTAAACGTTATAAACAGATTAATATTATTGATAGCAGTCCCCATTATTTCCATATTAAT
TATTAGCGTTGTAAATTATATGAATTTACAACAAATGCACAAACAACTTCAAACAGTATATGTCGATCGGCTACAACCTA
TTAAATGGCTTGGATCTATTGAGAGCAGCCTGTACCAAGAATTTAGTTATGTAAAGGAACTCATTATCACTGAAGATGAG
AATCGACGTACTACAATTTTAAATAAATTAAATGATACAAATAAAGAAACCGAAAAATTACAGGCTCAATACGAAAATAC
ATATATAACAGGCGAAGAAAAAAAACTCCTTAGCCAATATAAAGAAAAACTAGAAAACTATAAAAAACATCGTGCTCAAA
TGCTAGATTTCATTAAAGAGAATAAACTGAATCAAGCATATTCATTCTACCTAACTACAGTTGAACATAATTTATCAGCT
ACAGTAGGCGCTTTAAAAAATCTTAGTGATTATAACGAAAAGTTAGCTGAAGGTCTGTATAACGACAGCGAACACTCTTA
TAAACAAGTGATAAGCATAACCATTATTTTATTCATTACATGTTTAGTTCTTTGCATTCTTATCTCCTTATTTACTGCTA
AATCAATTATCAATCCAATCAATTCATTACGGAGCATAATGAATACAGCTGGAAAAGGGGATTTAACCATTGCCGTACCA
AAACAATACCATCATGAATTTGGTCATATGTTTAATAGTTTTGATCAAATGATATCAAACTTACAACAAATTATTAAAAA
TGTGATTCAAACAAGTGTACAAGTGAAAAGCTCTACAAATCATATTGTTGAAACAGCAACCGTTTCCTCTTCCACTATGG
ATAACATCGCAAATACAATGAAACAGTTGTCTCACCATATTAATGATCAGTCTGCAAATATTAAAGATAGTTCTACAGCA
ATGGATGAAATAGCAAATGGCGTACAAAGCATAGCCGAATCTTCTACAACGATTTCAAACTTAGCTATTTCTACTTCTGA
TAAGGCGAATGTAGGAACAGAAATCATTGAAAATTCCATTTCTCAAATGACAACTATTCATACTGTCATGGATGAAATAT
ATAAAGTTGTAGATCAATTAGTTATTCGTACGCAAGATATCGATAAAGCATTACAAACTATTACTTACATTTCTGAACAA
ACAAATCTATTATCTTTAAACGCTGCAATTGAATCTGCTCGCGCCGGTGAACATGGAAAGGGATTTGCTGTTGTATCTGA
AGAGGTGCGTAAACTTGCTGAACAATCAAAACAAGCAGCTACAGATATTACAAAACTTAATTTACTTGTACAAAATGATA
CAAAAGATGTAGTCAACGTTATGGGGAAAGGACAACAAGAAATTCAAGAAGGCATTCATGCTGTTCAAAATGCAAAATTA
GCATTCCATAATATTGTAAATCATATTAATGAAGTTACAGATCAAATACAAGATATAACAGCAAGTGCAGAAGAAATGTC
AGCAAGCTCAGAAGAAATAAATAGTGCACTTATTAATATCTCTTCAATTTCACAAAATATAGTTTCGGAGACTAATCATA
CATCCCAATCTTCACAAGCTCAGTCAGTATCAATACAGGACATTACAAATATGTCTCTTCAAATGCAAAAACTTGTTGAC
GAATTAGAAAAGTCCGCAACTCAATTTAAAATTAAAAACTTGTAA

Upstream 100 bases:

>100_bases
AATTACATTACTTTTTCTGTATATAATATGTAAATAATGTATAATTTTATTTGGATGCCCATTATATATTCAACTAAATA
ATTTAAGGTTAGGTGATTCT

Downstream 100 bases:

>100_bases
GTATATGAAAGACCAGCTAATTTAGTTGGTCTTTCTATTTTAATTACACATTCAGATTTACTTATATAATAACTGTCCTC
CAAAAAAATAAAGGATTCTG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 574

Protein sequence:

>574_residues
MLKILYLLNVINRLILLIAVPIISILIISVVNYMNLQQMHKQLQTVYVDRLQPIKWLGSIESSLYQEFSYVKELIITEDE
NRRTTILNKLNDTNKETEKLQAQYENTYITGEEKKLLSQYKEKLENYKKHRAQMLDFIKENKLNQAYSFYLTTVEHNLSA
TVGALKNLSDYNEKLAEGLYNDSEHSYKQVISITIILFITCLVLCILISLFTAKSIINPINSLRSIMNTAGKGDLTIAVP
KQYHHEFGHMFNSFDQMISNLQQIIKNVIQTSVQVKSSTNHIVETATVSSSTMDNIANTMKQLSHHINDQSANIKDSSTA
MDEIANGVQSIAESSTTISNLAISTSDKANVGTEIIENSISQMTTIHTVMDEIYKVVDQLVIRTQDIDKALQTITYISEQ
TNLLSLNAAIESARAGEHGKGFAVVSEEVRKLAEQSKQAATDITKLNLLVQNDTKDVVNVMGKGQQEIQEGIHAVQNAKL
AFHNIVNHINEVTDQIQDITASAEEMSASSEEINSALINISSISQNIVSETNHTSQSSQAQSVSIQDITNMSLQMQKLVD
ELEKSATQFKIKNL

Sequences:

>Translated_574_residues
MLKILYLLNVINRLILLIAVPIISILIISVVNYMNLQQMHKQLQTVYVDRLQPIKWLGSIESSLYQEFSYVKELIITEDE
NRRTTILNKLNDTNKETEKLQAQYENTYITGEEKKLLSQYKEKLENYKKHRAQMLDFIKENKLNQAYSFYLTTVEHNLSA
TVGALKNLSDYNEKLAEGLYNDSEHSYKQVISITIILFITCLVLCILISLFTAKSIINPINSLRSIMNTAGKGDLTIAVP
KQYHHEFGHMFNSFDQMISNLQQIIKNVIQTSVQVKSSTNHIVETATVSSSTMDNIANTMKQLSHHINDQSANIKDSSTA
MDEIANGVQSIAESSTTISNLAISTSDKANVGTEIIENSISQMTTIHTVMDEIYKVVDQLVIRTQDIDKALQTITYISEQ
TNLLSLNAAIESARAGEHGKGFAVVSEEVRKLAEQSKQAATDITKLNLLVQNDTKDVVNVMGKGQQEIQEGIHAVQNAKL
AFHNIVNHINEVTDQIQDITASAEEMSASSEEINSALINISSISQNIVSETNHTSQSSQAQSVSIQDITNMSLQMQKLVD
ELEKSATQFKIKNL
>Mature_574_residues
MLKILYLLNVINRLILLIAVPIISILIISVVNYMNLQQMHKQLQTVYVDRLQPIKWLGSIESSLYQEFSYVKELIITEDE
NRRTTILNKLNDTNKETEKLQAQYENTYITGEEKKLLSQYKEKLENYKKHRAQMLDFIKENKLNQAYSFYLTTVEHNLSA
TVGALKNLSDYNEKLAEGLYNDSEHSYKQVISITIILFITCLVLCILISLFTAKSIINPINSLRSIMNTAGKGDLTIAVP
KQYHHEFGHMFNSFDQMISNLQQIIKNVIQTSVQVKSSTNHIVETATVSSSTMDNIANTMKQLSHHINDQSANIKDSSTA
MDEIANGVQSIAESSTTISNLAISTSDKANVGTEIIENSISQMTTIHTVMDEIYKVVDQLVIRTQDIDKALQTITYISEQ
TNLLSLNAAIESARAGEHGKGFAVVSEEVRKLAEQSKQAATDITKLNLLVQNDTKDVVNVMGKGQQEIQEGIHAVQNAKL
AFHNIVNHINEVTDQIQDITASAEEMSASSEEINSALINISSISQNIVSETNHTSQSSQAQSVSIQDITNMSLQMQKLVD
ELEKSATQFKIKNL

Specific function: Receptor For The Attractant L-Serine And Related Amino Acids. Is Also Responsible For Chemotaxis Away From A Wide Range Of Repellents, Including Leucine, Indole, And Weak Acids. Chemotactic-Signal Transducers Respond To Changes In The Concentration Of At

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=439, Percent_Identity=26.1958997722096, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI1787690, Length=331, Percent_Identity=26.8882175226586, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788195, Length=280, Percent_Identity=28.2142857142857, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788194, Length=353, Percent_Identity=27.1954674220963, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789453, Length=335, Percent_Identity=26.865671641791, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 64310; Mature: 64310

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKILYLLNVINRLILLIAVPIISILIISVVNYMNLQQMHKQLQTVYVDRLQPIKWLGSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLYQEFSYVKELIITEDENRRTTILNKLNDTNKETEKLQAQYENTYITGEEKKLLSQY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEECCHHHHHHHHH
KEKLENYKKHRAQMLDFIKENKLNQAYSFYLTTVEHNLSATVGALKNLSDYNEKLAEGLY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDSEHSYKQVISITIILFITCLVLCILISLFTAKSIINPINSLRSIMNTAGKGDLTIAVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
KQYHHEFGHMFNSFDQMISNLQQIIKNVIQTSVQVKSSTNHIVETATVSSSTMDNIANTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHCCHHHHHHHHHHH
KQLSHHINDQSANIKDSSTAMDEIANGVQSIAESSTTISNLAISTSDKANVGTEIIENSI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHH
SQMTTIHTVMDEIYKVVDQLVIRTQDIDKALQTITYISEQTNLLSLNAAIESARAGEHGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCC
GFAVVSEEVRKLAEQSKQAATDITKLNLLVQNDTKDVVNVMGKGQQEIQEGIHAVQNAKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFHNIVNHINEVTDQIQDITASAEEMSASSEEINSALINISSISQNIVSETNHTSQSSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QSVSIQDITNMSLQMQKLVDELEKSATQFKIKNL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKILYLLNVINRLILLIAVPIISILIISVVNYMNLQQMHKQLQTVYVDRLQPIKWLGSI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLYQEFSYVKELIITEDENRRTTILNKLNDTNKETEKLQAQYENTYITGEEKKLLSQY
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEECCHHHHHHHHH
KEKLENYKKHRAQMLDFIKENKLNQAYSFYLTTVEHNLSATVGALKNLSDYNEKLAEGLY
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NDSEHSYKQVISITIILFITCLVLCILISLFTAKSIINPINSLRSIMNTAGKGDLTIAVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
KQYHHEFGHMFNSFDQMISNLQQIIKNVIQTSVQVKSSTNHIVETATVSSSTMDNIANTM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEHHCCHHHHHHHHHHH
KQLSHHINDQSANIKDSSTAMDEIANGVQSIAESSTTISNLAISTSDKANVGTEIIENSI
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHEECCCCCCHHHHHHHHHHH
SQMTTIHTVMDEIYKVVDQLVIRTQDIDKALQTITYISEQTNLLSLNAAIESARAGEHGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCC
GFAVVSEEVRKLAEQSKQAATDITKLNLLVQNDTKDVVNVMGKGQQEIQEGIHAVQNAKL
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHH
AFHNIVNHINEVTDQIQDITASAEEMSASSEEINSALINISSISQNIVSETNHTSQSSQA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
QSVSIQDITNMSLQMQKLVDELEKSATQFKIKNL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7921238; 7704255; 8969502; 9384377 [H]