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The map label for this gene is purL

Identifier: 49183309

GI number: 49183309

Start: 300211

End: 302430

Strand: Direct

Name: purL

Synonym: BAS0281

Alternate gene names: 49183309

Gene position: 300211-302430 (Clockwise)

Preceding gene: 49183308

Following gene: 49183310

Centisome position: 5.74

GC content: 40.77

Gene sequence:

>2220_bases
ATGTCGTTAATGCTTGAACCAAATCCAACACAAATTAAAGAAGAGCGCATATATGCGGAAATGGGGCTAACAGACGAAGA
GTTTGCCATGGTTGAAAAGATTTTAGGCCGTCTGCCAAATTATACAGAAACAGGTTTATTCTCTGTAATGTGGTCAGAAC
ATTGTAGTTATAAAAATTCAAAACCAGTGCTTCGAAAATTCCCAACAACAGGTGAGCGCGTTCTGCAAGGACCTGGGGAA
GGTGCTGGAATTGTAGATATCGGTGATAATCAAGCGGTTGTATTTAAAATGGAAAGTCATAACCATCCTTCTGCTATTGA
ACCATATCAAGGAGCAGCAACAGGCGTTGGTGGTATTATTCGTGACGTATTCTCTATGGGGGCACGTCCAGTAGCTCTAT
TAAACTCACTTCGCTTTGGGGAATTACAATCACCACGTGTGAAATACTTATTCGAAGAAGTAGTAGCAGGAATTGCGGGA
TACGGTAACTGTATCGGTATTCCGACTGTTGGCGGCGAAGTACAGTTTGATCCATGTTATGAAGGAAACCCACTTGTAAA
TGCAATGTGCGTAGGCTTAATTAACCACGAAGACATTAAAAAAGGGCAAGCGCACGGTGCTGGAAATACAGTAATGTACG
TAGGCGCATCAACTGGTCGTGATGGTATCCACGGTGCAACATTCGCATCTGAAGAGTTATCTGAAAGCTCAGAAGCGAAG
CGTCCAGCAGTTCAAGTAGGAGATCCATTTATGGAGAAACTTCTTATTGAAGCTTGCTTAGAACTTATTCAATCGGATGC
ACTTGTTGGAATTCAAGATATGGGTGCAGCTGGTTTAACATCATCTTCTGCAGAAATGGCAAGTAAAGCAGGAATGGGTA
TTGAAATGTACTTAGATGATGTACCGCAGCGAGAAACAGGAATGACACCATATGAAATGATGTTATCTGAATCACAAGAG
CGTATGTTAATTGTTGTGAAAAAAGGTAGAGAGCAAGAAATAGTAGATTTATTTGAGAAGTATGGTCTTGCAGCCGTTAC
GATGGGGAAAGTAACGGAAGACAAAATGCTTCGTTTATTCCATAAAGGTGAAATGGTAGCTGAAGTGCCAGCAGATGCTC
TTGCAGAAGAAGCACCAATTTATCATAAACCATCAAAAGAAGCAGCATATTTTGCTGAATTCCAGCAGATGAAAATGGAA
ACACCAAAAGTAGAAAATTATAAAGAAACGTTATTCGCTCTATTACAACAACCGACGATTGCAAGTAAAGAGTGGGTTTA
TGATCAATATGATTATCAAGTTCGCACAAGCACAGTTGTTACACCAGGTTCAGATGCAGCAGTTGTACGTGTACGCGGTA
CAGAAAAAGGATTAGCAATGACGACAGATTGTAACTCTCGCTACATTTATTTAGATCCAGAAGTGGGCGGTAAAATTGCA
GTAGCAGAGGCAGCACGTAATATCGTATGTTCTGGGGGAGAGCCTCTTGCAATTACAGATTGCTTAAACTTCGGTAATCC
AGAAAAACCAGAAATCTTCTGGCAAATTGAGAAATCAGTAGATGGTATGAGTGAAGCTTGTCGTACGTTACAAACACCAG
TTATCGGCGGAAACGTATCAATGTATAACGAGCGTAGTGGTGAAGCGGTATACCCAACACCGACAGTTGGGATGGTTGGA
CTTGTACATGATTTAAAACATGTAACAACACAAGAGTTTAAGCAAGCCGGCGATTTAGTTTATGTCATTGGAGAGACGAA
AGCTGAGTTTGGTGGAAGTGAATTACAGAAAATGCTTCACGGAAAAATTTTCGGCCAATCACCAAGTATCGATTTAGACG
TAGAATTAAAACGTCAAAAACAAGTATTAGCAGCCATTCAAGCTGGCCTTGTTCAATCTGCACATGACGTTGCTGAAGGT
GGTTTAGCGGTTGCGATTTCAGAAAGTGCAATTGGTGCTAACGGCTTAGGTGCTACTGTGAAATTAGACGGGGAAGCAAC
AGCTGCATTATTTGCGGAATCACAATCTCGCTTCGTAATAACGGTAAAACGTGAAAATAAAGAAGCGTTCGAGAAAGCGG
TAGAAGCCATTCAAGTTGGTGAAGTAACAAATACAAATGAAGTAACAATTCATAATGAAGAAAATGAAGTATTACTTACA
GCAAATGTAGATGAAATGAGAAAGGCTTGGAAAGGGGCAATCCCATGCTTGCTGAAATAA

Upstream 100 bases:

>100_bases
GGTATGATGCCACACCCAGAGCGTGCTGTAGATGAATTACTTGGCGGTGCTGAAGGGTTAAAAGTCTTTCAATCTATCTT
AAAACAGTGGAGGGAAACAT

Downstream 100 bases:

>100_bases
AGGGGTTAAACGAAGAATGTGGCGTATTCGGAATTTGGGGGCATGAAAATGCGGCACAAGTTTCATACTACGGATTGCAC
AGTTTACAGCACCGTGGGCA

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II

Number of amino acids: Translated: 739; Mature: 738

Protein sequence:

>739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKME
TPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEG
GLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK

Sequences:

>Translated_739_residues
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGE
GAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAG
YGNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQE
RMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKME
TPKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVG
LVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEG
GLAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
ANVDEMRKAWKGAIPCLLK
>Mature_738_residues
SLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNSKPVLRKFPTTGERVLQGPGEG
AGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGIIRDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGY
GNCIGIPTVGGEVQFDPCYEGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAKR
PAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDDVPQRETGMTPYEMMLSESQER
MLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLFHKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMET
PKVENYKETLFALLQQPTIASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIAV
AEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVSMYNERSGEAVYPTPTVGMVGL
VHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLHGKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGG
LAVAISESAIGANGLGATVKLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLTA
NVDEMRKAWKGAIPCLLK

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family

Homologues:

Organism=Homo sapiens, GI31657129, Length=722, Percent_Identity=24.2382271468144, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI48994899, Length=767, Percent_Identity=25.2933507170795, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17553022, Length=683, Percent_Identity=21.9619326500732, Blast_Score=104, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321498, Length=722, Percent_Identity=22.5761772853186, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24582111, Length=637, Percent_Identity=24.1758241758242, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24582109, Length=637, Percent_Identity=24.1758241758242, Blast_Score=104, Evalue=3e-22,
Organism=Drosophila melanogaster, GI17137292, Length=637, Percent_Identity=24.1758241758242, Blast_Score=104, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURL_BACAA (C3PBN0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002864912.1
- ProteinModelPortal:   C3PBN0
- SMR:   C3PBN0
- EnsemblBacteria:   EBBACT00000130097
- GeneID:   7851020
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_0349
- GeneTree:   EBGT00050000002932
- ProtClustDB:   PRK01213
- GO:   GO:0005737
- HAMAP:   MF_00420
- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188
- TIGRFAMs:   TIGR01736

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C; SSF56042 AIR_synth_C; SSF55326 PurM_N-like

EC number: =6.3.5.3

Molecular weight: Translated: 80176; Mature: 80045

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNS
CCEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLH
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATV
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEE
KLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SLMLEPNPTQIKEERIYAEMGLTDEEFAMVEKILGRLPNYTETGLFSVMWSEHCSYKNS
CEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCC
KPVLRKFPTTGERVLQGPGEGAGIVDIGDNQAVVFKMESHNHPSAIEPYQGAATGVGGII
CCHHHHCCCCCHHHHCCCCCCCCEEEECCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHH
RDVFSMGARPVALLNSLRFGELQSPRVKYLFEEVVAGIAGYGNCIGIPTVGGEVQFDPCY
HHHHHCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCEEEECCCC
EGNPLVNAMCVGLINHEDIKKGQAHGAGNTVMYVGASTGRDGIHGATFASEELSESSEAK
CCCCHHHHHHHHHCCHHHHHCCCCCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHC
RPAVQVGDPFMEKLLIEACLELIQSDALVGIQDMGAAGLTSSSAEMASKAGMGIEMYLDD
CCCEECCCHHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCCCHHHHHHHCCCCEEEEECC
VPQRETGMTPYEMMLSESQERMLIVVKKGREQEIVDLFEKYGLAAVTMGKVTEDKMLRLF
CCCCCCCCCHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCHHHHHHHH
HKGEMVAEVPADALAEEAPIYHKPSKEAAYFAEFQQMKMETPKVENYKETLFALLQQPTI
HCCCEEECCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCC
ASKEWVYDQYDYQVRTSTVVTPGSDAAVVRVRGTEKGLAMTTDCNSRYIYLDPEVGGKIA
CCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCCEEEEECCCCEEEEECCCCCCEEE
VAEAARNIVCSGGEPLAITDCLNFGNPEKPEIFWQIEKSVDGMSEACRTLQTPVIGGNVS
EEHHHCCEEECCCCCEEEEEHHCCCCCCCCEEEEEEHHHHCHHHHHHHHHCCCEECCCEE
MYNERSGEAVYPTPTVGMVGLVHDLKHVTTQEFKQAGDLVYVIGETKAEFGGSELQKMLH
EECCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHCCHHHHHHHHH
GKIFGQSPSIDLDVELKRQKQVLAAIQAGLVQSAHDVAEGGLAVAISESAIGANGLGATV
HHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEE
KLDGEATAALFAESQSRFVITVKRENKEAFEKAVEAIQVGEVTNTNEVTIHNEENEVLLT
EECCCCEEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEE
ANVDEMRKAWKGAIPCLLK
ECHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA