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The map label for this gene is purQ

Identifier: 49183308

GI number: 49183308

Start: 299544

End: 300227

Strand: Direct

Name: purQ

Synonym: BAS0280

Alternate gene names: 49183308

Gene position: 299544-300227 (Clockwise)

Preceding gene: 49183307

Following gene: 49183309

Centisome position: 5.73

GC content: 37.87

Gene sequence:

>684_bases
GTGAAATTTGCCGTAATAGTATTTCCAGGTTCGAACTGTGATGTTGATATGTTCCATGCAATTAAAGATGAGCTTGGCGA
AGAAGTAGATTACGTTTGGCACGATACAGAGAATTTAGATGAATATGATGCAATTCTACTACCAGGTGGTTTCTCTTACG
GTGACTACTTACGCTGCGGTGCTATTTCTCGCTTTGCGAATGCAATGAAAGCAGTACAGAAAGCTGCTGAGCAAGGAAAG
CCAATTTTAGGTGTATGTAATGGATTCCAGATTCTTGTTGAATCAGGATTACTACCAGGGGCATTAATGAGAAACGAAAA
CTTAAAATTTATGTGTCGAACGGTTCAGTTACGTGTTGAAAATAATGAAACAATGTTTACATCACAATATGAAAAAGATG
AAGTAATCAATATTCCAATTGCACATGGTGAGGGGAATTACTATTGTGATGAAGAGACTCTTAAACAATTAGAAGAGAAT
AATCAAATCGCATTTCGTTACGTAGAAAACCCGAACGGAAGCGTTTCAGATATTGCTGGTATTGTAAACGAAAAAGGAAA
TGTACTTGGTATGATGCCACACCCAGAGCGTGCTGTAGATGAATTACTTGGCGGTGCTGAAGGGTTAAAAGTCTTTCAAT
CTATCTTAAAACAGTGGAGGGAAACATATGTCGTTAATGCTTGA

Upstream 100 bases:

>100_bases
TATCTGACCTTGACGCAAAGGTAAAGGAAATGTGTGAAAAACTATTAGCGAACGTTGTAATGGAAGACTTCCGTTATGAA
GTTGAGGAGGTTGTCGCACA

Downstream 100 bases:

>100_bases
ACCAAATCCAACACAAATTAAAGAAGAGCGCATATATGCGGAAATGGGGCTAACAGACGAAGAGTTTGCCATGGTTGAAA
AGATTTTAGGCCGTCTGCCA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Sequences:

>Translated_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
>Mature_227_residues
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCGAISRFANAMKAVQKAAEQGK
PILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVENNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEEN
NQIAFRYVENPNGSVSDIAGIVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17553022, Length=235, Percent_Identity=26.8085106382979, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=243, Percent_Identity=29.6296296296296, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24582111, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24582109, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI17137292, Length=230, Percent_Identity=28.695652173913, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_BACAA (C3PBM9)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002864911.1
- ProteinModelPortal:   C3PBM9
- SMR:   C3PBM9
- EnsemblBacteria:   EBBACT00000128698
- GeneID:   7853246
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_0348
- GeneTree:   EBGT00050000001675
- ProtClustDB:   PRK03619
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF00117 GATase

EC number: =6.3.5.3

Molecular weight: Translated: 25411; Mature: 25411

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS51273 GATASE_TYPE_1; PS00442 GATASE_TYPE_I

Important sites: ACT_SITE 86-86 ACT_SITE 194-194 ACT_SITE 196-196

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCHHHCCCCCEEEEEEEEEEEC
NNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MKFAVIVFPGSNCDVDMFHAIKDELGEEVDYVWHDTENLDEYDAILLPGGFSYGDYLRCG
CEEEEEEECCCCCCHHHHHHHHHHHCCHHCEEECCCCCCCCCCEEEECCCCCCCCHHHHH
AISRFANAMKAVQKAAEQGKPILGVCNGFQILVESGLLPGALMRNENLKFMCRTVQLRVE
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHCCCCCCHHHCCCCCEEEEEEEEEEEC
NNETMFTSQYEKDEVINIPIAHGEGNYYCDEETLKQLEENNQIAFRYVENPNGSVSDIAG
CCCEEEECCCCCCCEEEEEEEECCCCEEECHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
IVNEKGNVLGMMPHPERAVDELLGGAEGLKVFQSILKQWRETYVVNA
HHCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA