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The map label for this gene is rrf

Identifier: 46447510

GI number: 46447510

Start: 2236436

End: 2236987

Strand: Reverse

Name: rrf

Synonym: pc1876

Alternate gene names: 46447510

Gene position: 2236987-2236436 (Counterclockwise)

Preceding gene: 46447511

Following gene: 46447509

Centisome position: 92.65

GC content: 34.6

Gene sequence:

>552_bases
ATGAGCATAGTTGATCAAACTAAAACCAAAATGATAACGGCAATTGAACATTTAAAGAATGATTTGAAAAATATTCGTAC
GGGTCGTGCCAATCCGGGAATGGTTGAGCATGTGATGATAGAAGTCTATGGAAGCCCTATGCGTCTAAAAGATGTTGCTT
CGATTTCTGCTCCCGAGGCGCGTCAACTATTAATTACTCCCTTTGATCCTCAAAATGCGGGATCGATTGGCAAAGGTATT
GAAAAAGCAAATTTAGGTTTAATGCCTATTGTTGATGCGCATTCTGTTCGTATAAAAATTCCTCCTATGACAGAAGAAAT
TCGAAAAAAAATGGCAAAAATTTGCCATGAAGAAAAAGAAAAGACAAAAGTTAGTATTCGAAATATCAGACGCGATGCCA
ATGAATTAGCAAGAAAACAAAAATCGGAAGGAATCATTGCAGAAGATGTTTTAAAAAAACTCGAAAAAAATATTCAAGAG
TTAACGGATAAGTTTTGTAAAGAAGCTGATGAAATCGCGGAAAAAAAAGAAAAAGAAATTTCCACAATTTAA

Upstream 100 bases:

>100_bases
GATTAGACCATGTCTTAACAGATTATAGTCATGGAACTTTAGTTGATGATGGAGAAATTGGTCATGAAGCTAACAAGCTA
GATAGATAATAGGAGTTAAT

Downstream 100 bases:

>100_bases
TGCTTGTAAAAAAATGAGGCTTTATTTTAGGATAAAGCCTCTTCAATCAAAAATTGAAGAATAGTTTGGATCCTATTTAT
TCTAAATACGATTTAAGTTT

Product: putative ribosome recycling factor (ribosome releasing factor)

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEARQLLITPFDPQNAGSIGKGI
EKANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKEKTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQE
LTDKFCKEADEIAEKKEKEISTI

Sequences:

>Translated_183_residues
MSIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEARQLLITPFDPQNAGSIGKGI
EKANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKEKTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQE
LTDKFCKEADEIAEKKEKEISTI
>Mature_182_residues
SIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEARQLLITPFDPQNAGSIGKGIE
KANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKEKTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQEL
TDKFCKEADEIAEKKEKEISTI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=179, Percent_Identity=25.6983240223464, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1786368, Length=171, Percent_Identity=34.5029239766082, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_PARUW (Q6M9Z9)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008875.1
- ProteinModelPortal:   Q6M9Z9
- SMR:   Q6M9Z9
- STRING:   Q6M9Z9
- GeneID:   2781135
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1876
- NMPDR:   fig|264201.1.peg.1876
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q6M9Z9
- ProtClustDB:   CLSK2762520
- BioCyc:   CPRO264201:PC1876-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20638; Mature: 20507

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEA
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
RQLLITPFDPQNAGSIGKGIEKANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKE
CEEEECCCCCCCCCCHHCCHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHH
KTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQELTDKFCKEADEIAEKKEKEI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STI
CCC
>Mature Secondary Structure 
SIVDQTKTKMITAIEHLKNDLKNIRTGRANPGMVEHVMIEVYGSPMRLKDVASISAPEA
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCC
RQLLITPFDPQNAGSIGKGIEKANLGLMPIVDAHSVRIKIPPMTEEIRKKMAKICHEEKE
CEEEECCCCCCCCCCHHCCHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHH
KTKVSIRNIRRDANELARKQKSEGIIAEDVLKKLEKNIQELTDKFCKEADEIAEKKEKEI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA