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The map label for this gene is gidA

Identifier: 46447473

GI number: 46447473

Start: 2196161

End: 2198038

Strand: Reverse

Name: gidA

Synonym: pc1839

Alternate gene names: 46447473

Gene position: 2198038-2196161 (Counterclockwise)

Preceding gene: 46447474

Following gene: 46447472

Centisome position: 91.04

GC content: 39.72

Gene sequence:

>1878_bases
ATGATGCTTTGGAAATTTCCTGTTCGTTATGATGTAATTGTTATTGGTGGAGGGCATGCAGGCTGCGAAGCAGCATTGGC
ATCTGCACGAATGGGGTTGAGAACTTTATTACTCACAATGAATTTGGATACAATAGCCAAAATGAGTTGTAATCCTGCTG
TAGGAGGAATCGCTAAAGGACATATCGTTAGAGAAATCGATGCATTGGGTGGGGAAATGGGTAAAGTGATTGATGTCACT
GGGATCCAATATCGCATGTTAAATGCGACTAAAGGCCCTGCCGTTTGGGCACCTCGCGCGCAAGCCGACAAACTTGCTTA
TCAAAGTGAGATGAAACACCGTATGGAGCGAGTCTCTAACTTGGATATCAAGCAAGGCACAATTGAAGATTTGTTAATTG
AAAACGATCATATTTGTGGCGTGATTACGAAAGAAGGAATTAGTTATGATTGCCAAGCGATTGTTCTTTCTTCTGGGACA
TTTTTAAGAGGCCTTTTACATATTGGTGAAACAAATTATTCGGGGGGTAGAGCTGGAGACCAGCCTTCAGTAGGTATGTC
AGCTAGCTTAGAAAAATATGGTTTGAAATTAGGTCGATTAAAGACGGGAACTCCTCCTAGAATCAATAAACGATCCATTG
ACTTTAGTTGCACAGAAGAACAGCCGGGTGATCCGGGAGTCAAATTTTCTTACGATAATGAGGGAATTCCTCGTTTGCCG
CAAGTGTCTTGCTACATTACTTATACGACAGAAGAAACAAAACAAATTATTTTATCCAACATTCATCGCTCTCCTATGTA
TTCAGGCAAAATCAAAGGAGTGGGACCTCGTTATTGCCCTTCCATTGAAGATAAGGTTGTTCGTTTTTCGGATAAAGAAC
GCCATCAAATTTTTTTGGAGCCTGAAGGACTCCAAACCCAAGAAGTTTACGTCAATGGAGTCTCTTCTTCATTACCCTTT
GATGTACAATTGGCATTTATCAAAAGTATCCCTGCACTTCGTCATGCTGAAATCATGAGACCTGCTTACGCAATTGAATA
TGATTATGTTATAAGTGGTCAAATTGATTTTTCTCTCGAATGTAAAAAAATTGGAGGCCTTTTCTTAGCTGGCCAAATTA
ATGGAACGTCTGGTTATGAAGAAGCTGCCGGCCAGGGATTAATGGCAGGAATTAACGCTGCGAATAAAGTGATGGGTAAA
GCCCCCCTAATTTTAAAACGTTCGGAAGCATATATAGGAGTGATGATCGATGATCTAGTCACAAAAGGTTTAGATGAACC
TTACCGAATGTTTACAAGTCGTGCAGAGCATCGTTTATTACTTCGGCAAGACAATGCCGATCTTCGTTTAAGACGCTATG
GCTATGAAGTGGGATTAGTCGATCAAACGCGTTATGATCGGGTAAAAGAAAAGCAAAGAATCATGGAGGAAGAAAGCGAA
CGTTTAGCAAAAACATTTAAGCAAGTATCTAATAAGGGATATACATTAACTCAATTATTATGCCGACCCGAAAATACATA
TGCTTCCTTGCTAAAAGAATATCCAGATGTGATGCAAAATTTTGGAGAAGAAATTAATTTTCAAATTGAATTAAATTTAA
AATATGCGGGTTATATCGATCGCCAAACAAGTGAAGTGGCAAAATTGGCGCATGTGGAGAAAATTCAAATTCCGATAGGG
TTTGATTTTTCAACTGTAAACGGTTTGCGTAACGAAGCAAAGCAAAAATTGAACCAGATCGCTCCACGCCATTTAGGCCA
AGCTTTACGCATTTCAGGAGTTTCTCCTGCAGATATTTCGATTTTAATGATTGCTCTTACGCGGTATCAAGAGCCAATAG
AAAAAGAACGGCTAACATCTGATTGTTCCGAGGCATAA

Upstream 100 bases:

>100_bases
CAACTAATACAAATTTATTAAATTGATTAATTTATTTTGTAAAACTTGAGTTTTTATTTTAAAATTTTGGATTTAAATAT
TAATTAAATGAGTGTTTTGA

Downstream 100 bases:

>100_bases
GAGGTCATGCTTGAATGTAATGTTGTGCAGTTAAAAAACGTTCCTATTTTAACTCAGTTAAAATGGGAAGAAGCTTTACT
ACGTACAAAACACGACAACT

Product: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA

Products: NA

Alternate protein names: Glucose-inhibited division protein A

Number of amino acids: Translated: 625; Mature: 625

Protein sequence:

>625_residues
MMLWKFPVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKGHIVREIDALGGEMGKVIDVT
GIQYRMLNATKGPAVWAPRAQADKLAYQSEMKHRMERVSNLDIKQGTIEDLLIENDHICGVITKEGISYDCQAIVLSSGT
FLRGLLHIGETNYSGGRAGDQPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGDPGVKFSYDNEGIPRLP
QVSCYITYTTEETKQIILSNIHRSPMYSGKIKGVGPRYCPSIEDKVVRFSDKERHQIFLEPEGLQTQEVYVNGVSSSLPF
DVQLAFIKSIPALRHAEIMRPAYAIEYDYVISGQIDFSLECKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVMGK
APLILKRSEAYIGVMIDDLVTKGLDEPYRMFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESE
RLAKTFKQVSNKGYTLTQLLCRPENTYASLLKEYPDVMQNFGEEINFQIELNLKYAGYIDRQTSEVAKLAHVEKIQIPIG
FDFSTVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADISILMIALTRYQEPIEKERLTSDCSEA

Sequences:

>Translated_625_residues
MMLWKFPVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKGHIVREIDALGGEMGKVIDVT
GIQYRMLNATKGPAVWAPRAQADKLAYQSEMKHRMERVSNLDIKQGTIEDLLIENDHICGVITKEGISYDCQAIVLSSGT
FLRGLLHIGETNYSGGRAGDQPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGDPGVKFSYDNEGIPRLP
QVSCYITYTTEETKQIILSNIHRSPMYSGKIKGVGPRYCPSIEDKVVRFSDKERHQIFLEPEGLQTQEVYVNGVSSSLPF
DVQLAFIKSIPALRHAEIMRPAYAIEYDYVISGQIDFSLECKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVMGK
APLILKRSEAYIGVMIDDLVTKGLDEPYRMFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESE
RLAKTFKQVSNKGYTLTQLLCRPENTYASLLKEYPDVMQNFGEEINFQIELNLKYAGYIDRQTSEVAKLAHVEKIQIPIG
FDFSTVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADISILMIALTRYQEPIEKERLTSDCSEA
>Mature_625_residues
MMLWKFPVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKGHIVREIDALGGEMGKVIDVT
GIQYRMLNATKGPAVWAPRAQADKLAYQSEMKHRMERVSNLDIKQGTIEDLLIENDHICGVITKEGISYDCQAIVLSSGT
FLRGLLHIGETNYSGGRAGDQPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGDPGVKFSYDNEGIPRLP
QVSCYITYTTEETKQIILSNIHRSPMYSGKIKGVGPRYCPSIEDKVVRFSDKERHQIFLEPEGLQTQEVYVNGVSSSLPF
DVQLAFIKSIPALRHAEIMRPAYAIEYDYVISGQIDFSLECKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVMGK
APLILKRSEAYIGVMIDDLVTKGLDEPYRMFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESE
RLAKTFKQVSNKGYTLTQLLCRPENTYASLLKEYPDVMQNFGEEINFQIELNLKYAGYIDRQTSEVAKLAHVEKIQIPIG
FDFSTVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADISILMIALTRYQEPIEKERLTSDCSEA

Specific function: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34

COG id: COG0445

COG function: function code D; NAD/FAD-utilizing enzyme apparently involved in cell division

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MnmG family

Homologues:

Organism=Homo sapiens, GI74024895, Length=625, Percent_Identity=42.4, Blast_Score=472, Evalue=1e-133,
Organism=Homo sapiens, GI19882217, Length=650, Percent_Identity=40.7692307692308, Blast_Score=458, Evalue=1e-129,
Organism=Homo sapiens, GI183227703, Length=665, Percent_Identity=39.8496240601504, Blast_Score=453, Evalue=1e-127,
Organism=Escherichia coli, GI2367273, Length=619, Percent_Identity=52.827140549273, Blast_Score=637, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17534255, Length=617, Percent_Identity=39.2220421393841, Blast_Score=429, Evalue=1e-120,
Organism=Saccharomyces cerevisiae, GI6321202, Length=620, Percent_Identity=43.0645161290323, Blast_Score=479, Evalue=1e-136,
Organism=Drosophila melanogaster, GI24658174, Length=619, Percent_Identity=42.3263327948304, Blast_Score=467, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MNMG_PARUW (Q6MA36)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008838.1
- ProteinModelPortal:   Q6MA36
- SMR:   Q6MA36
- STRING:   Q6MA36
- GeneID:   2780896
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1839
- NMPDR:   fig|264201.1.peg.1839
- eggNOG:   COG0445
- HOGENOM:   HBG284774
- OMA:   GIQFRVL
- PhylomeDB:   Q6MA36
- ProtClustDB:   PRK05192
- BioCyc:   CPRO264201:PC1839-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00129
- InterPro:   IPR004416
- InterPro:   IPR002218
- InterPro:   IPR020595
- TIGRFAMs:   TIGR00136

Pfam domain/function: PF01134 GIDA

EC number: NA

Molecular weight: Translated: 69588; Mature: 69588

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS01280 GIDA_1; PS01281 GIDA_2

Important sites: BINDING 128-128 BINDING 183-183 BINDING 372-372

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLWKFPVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKG
CCEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCCCCCCCCC
HIVREIDALGGEMGKVIDVTGIQYRMLNATKGPAVWAPRAQADKLAYQSEMKHRMERVSN
HHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHC
LDIKQGTIEDLLIENDHICGVITKEGISYDCQAIVLSSGTFLRGLLHIGETNYSGGRAGD
CCCCCCCHHHHEECCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCC
QPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGDPGVKFSYDNEGIPRLP
CCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCC
QVSCYITYTTEETKQIILSNIHRSPMYSGKIKGVGPRYCPSIEDKVVRFSDKERHQIFLE
CEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEC
PEGLQTQEVYVNGVSSSLPFDVQLAFIKSIPALRHAEIMRPAYAIEYDYVISGQIDFSLE
CCCCCCCEEEEECCCCCCCCEEEEHHHHCCCCHHHHHHHCCEEEEEEEEEEECEEEEEEE
CKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVMGKAPLILKRSEAYIGVMIDDLV
EEECCCEEEEEEECCCCCHHHHCCCCEEECCCHHHHHHCCCCEEEEECCCEEEEHHHHHH
TKGLDEPYRMFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESE
HHCCCHHHHHHHHHHHHEEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHH
RLAKTFKQVSNKGYTLTQLLCRPENTYASLLKEYPDVMQNFGEEINFQIELNLKYAGYID
HHHHHHHHHHCCCCEEEHEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCC
RQTSEVAKLAHVEKIQIPIGFDFSTVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADIS
CHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEECCCCCCHHH
ILMIALTRYQEPIEKERLTSDCSEA
HHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure
MMLWKFPVRYDVIVIGGGHAGCEAALASARMGLRTLLLTMNLDTIAKMSCNPAVGGIAKG
CCEEEECCEEEEEEEECCCCCHHHHHHHHHHHHHHHHEEECHHHHHHCCCCCCCCCCCCC
HIVREIDALGGEMGKVIDVTGIQYRMLNATKGPAVWAPRAQADKLAYQSEMKHRMERVSN
HHHHHHHHCCCCCCCEEEECCCEEEEEECCCCCCEECCCCHHHHHHHHHHHHHHHHHHHC
LDIKQGTIEDLLIENDHICGVITKEGISYDCQAIVLSSGTFLRGLLHIGETNYSGGRAGD
CCCCCCCHHHHEECCCCEEEEEECCCCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCC
QPSVGMSASLEKYGLKLGRLKTGTPPRINKRSIDFSCTEEQPGDPGVKFSYDNEGIPRLP
CCCCCCCCCHHHHCCEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCEEEECCCCCCCCC
QVSCYITYTTEETKQIILSNIHRSPMYSGKIKGVGPRYCPSIEDKVVRFSDKERHQIFLE
CEEEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHEECCCCCCCEEEEC
PEGLQTQEVYVNGVSSSLPFDVQLAFIKSIPALRHAEIMRPAYAIEYDYVISGQIDFSLE
CCCCCCCEEEEECCCCCCCCEEEEHHHHCCCCHHHHHHHCCEEEEEEEEEEECEEEEEEE
CKKIGGLFLAGQINGTSGYEEAAGQGLMAGINAANKVMGKAPLILKRSEAYIGVMIDDLV
EEECCCEEEEEEECCCCCHHHHCCCCEEECCCHHHHHHCCCCEEEEECCCEEEEHHHHHH
TKGLDEPYRMFTSRAEHRLLLRQDNADLRLRRYGYEVGLVDQTRYDRVKEKQRIMEEESE
HHCCCHHHHHHHHHHHHEEEEEECCCCEEEEEECCEEEECCCHHHHHHHHHHHHHHHHHH
RLAKTFKQVSNKGYTLTQLLCRPENTYASLLKEYPDVMQNFGEEINFQIELNLKYAGYID
HHHHHHHHHHCCCCEEEHEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCC
RQTSEVAKLAHVEKIQIPIGFDFSTVNGLRNEAKQKLNQIAPRHLGQALRISGVSPADIS
CHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEECCCCCCHHH
ILMIALTRYQEPIEKERLTSDCSEA
HHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA