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The map label for this gene is ntpI [H]

Identifier: 46447311

GI number: 46447311

Start: 2013253

End: 2015169

Strand: Reverse

Name: ntpI [H]

Synonym: pc1677

Alternate gene names: 46447311

Gene position: 2015169-2013253 (Counterclockwise)

Preceding gene: 46447312

Following gene: 46447310

Centisome position: 83.46

GC content: 33.91

Gene sequence:

>1917_bases
ATGCGTAAAGATGTTAAAAAATTCTTATTTCTTGGATTAGCAGATGAAAAAAAATCTTTTTTTCAACAAGCTCAAAAACT
TGGGTTTATTCACTTTATTGATCCTTGCCAAACTTCAAACCGTGATATACCTGAAGCTATAGAAAAATTGACTACTGCAA
TAAAAATTTTGCGTGGCTTACCTTTCGTTGAACAAGAGGAAAATTATCAACCCTTAAACTCAAACACGATAGTAGAAAAT
ATTCTTTCGCTATGTAAAAAAAGTGAGAAAAAACAAGAAGAAATCCGTGTATTAAGATTAGAAATGTCACGGATTGAAAT
TTTTGGGAATTTTTCTTTAGAAGATATTTATTTCATTGAAAATGCAGGTAAACGAAAAATTCAATTTTTTGTTGCACGCT
CTAGTGCGTTTAAAGAACAAGATCCGCCTGATGAGTTGATTTATATCTCTTCAAACCAAGGTTTGGATTATTACTTTGCT
ATTAACGAACAATCAGTTTCTTATGATAAACTCATTGAAATTAAGATCAATCGATCTTTGCAAAACTTAAATCAACAATT
AATTGAAGCAAATTCAGAAAGAAGACGAATTGATCATCAACTTAAAGAGTTAGCAAAATACAATGAATTTTTGCATCATG
CCCTAGTAAATAAACTCAATAGTCATCATCTTAATCACGCACAGACCTATGTTCAACAAACGATGGATGGTTTACTATTC
GCTGTTGAAGGATGGGTGCCGGCGAACAAAGTTGATCAAATAGAAAAAGTCACGAAAGCTTTAAATGTCTATATTGATGA
AGTGGCAATTGAAGCCTCAGATGTTATTCCTACTTATTTAGAAAATAGTGGTTTTAGTAGATTGGGAGAAGATTTAGTTA
ATATTTATGATACACCGTCATCTTCAGATCATGATCCTTCAAATTGGGTTCTTTGGTGTTTTACGCTCTTTTTTGCTTTT
ATTATCGGTGATGCCGGTTACGGATTTATTTATTTAGCTTTAGCACTTTTTCTTCGTTACAAATATCCTGATTTGAAAGG
TTTAAGTAAACGTTTACTGAATCTTTTTACTATTTTATGTGTAGGATGTATTGTGTGGGGGACTTTGATGACCTCGTTTT
TTGGGATGCAAATCGATATCAATAATCCCATACGTAAAATTTCTCTCGTACAATGGTTATCAAAGGAAAAAATTGCTTAT
CACATTGCTCATCAGGATAGTACTTACCAAAAATGGCTTCAAGCATATCCTACATTAGCAAATCATGCTGATGCTCATGA
GTTTGTTTCGTTTATTCCAGATTGGGAGCCAAGCAAAGGCCCAGTTATTTTAAGTATGATCAGTGATACAATTATGTTTG
AATTGGCTTTATTTATTGGTGTCGTTCATCTTTTGCTATCGTTGTTGCGCTATGGATTGCGCAACATTCCAAATTTAGGG
TGGGCCGCATTTCTGATTGGAGCTTACCTTTATTTCCCTTCTCACCTTCAAGCTCCAAGTTTTCTTAATTTTATTGGAAA
TGTGGATTTGAATGAAGGGGGAAAAATAGGTTTACAATTTATGATAGGGGGTATTGCTTTTGCATGGATAACCTCTATTT
GGAAAAATGGGTGGACGGGAATTTTTGAAATCACAGTTTTAATTCAAGTTTTTGCCGATGTCTTATCTTATTTACGTCTT
TATGCTTTGGCTCTGGCCGGAGCTGTTGTGGGCGCGACAGTCAATGAAATTGCCAGTGGATTACCCTTATTAGCTTCTTT
CTTTTTGGTTATGATTGCCCATTTTGTGAATTTGATTTTGGGAACAATGGGAGGAGTAATTCATGGATTGCGACTTAACT
TTTTAGAGTGGTATCACTACTCTTTTGAGGGGGGAGGAAAAAAATTTCAACCACTTAAATTATTAAAAATCGAGTAA

Upstream 100 bases:

>100_bases
CAGCAATTAGCTGCTGTTTCTCGAGCAAAAGTTGCTAAAACAAAAATTGAAGCGAATAAGAAAGCTTTTCTTTTGACTCT
TTCCAAAAAGGAGTTCAAAC

Downstream 100 bases:

>100_bases
ATCAATAGGAGTTTTCAATGGATATTAATATGGTTGGCCCTGCAATGGCACTAGGATTGAGTAGTATGGGATGCAGTATT
GGATGTTGGATTGCAGGGTC

Product: V-type ATP synthase subunit I

Products: ADP; phosphate; H+

Alternate protein names: V-ATPase subunit I [H]

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MRKDVKKFLFLGLADEKKSFFQQAQKLGFIHFIDPCQTSNRDIPEAIEKLTTAIKILRGLPFVEQEENYQPLNSNTIVEN
ILSLCKKSEKKQEEIRVLRLEMSRIEIFGNFSLEDIYFIENAGKRKIQFFVARSSAFKEQDPPDELIYISSNQGLDYYFA
INEQSVSYDKLIEIKINRSLQNLNQQLIEANSERRRIDHQLKELAKYNEFLHHALVNKLNSHHLNHAQTYVQQTMDGLLF
AVEGWVPANKVDQIEKVTKALNVYIDEVAIEASDVIPTYLENSGFSRLGEDLVNIYDTPSSSDHDPSNWVLWCFTLFFAF
IIGDAGYGFIYLALALFLRYKYPDLKGLSKRLLNLFTILCVGCIVWGTLMTSFFGMQIDINNPIRKISLVQWLSKEKIAY
HIAHQDSTYQKWLQAYPTLANHADAHEFVSFIPDWEPSKGPVILSMISDTIMFELALFIGVVHLLLSLLRYGLRNIPNLG
WAAFLIGAYLYFPSHLQAPSFLNFIGNVDLNEGGKIGLQFMIGGIAFAWITSIWKNGWTGIFEITVLIQVFADVLSYLRL
YALALAGAVVGATVNEIASGLPLLASFFLVMIAHFVNLILGTMGGVIHGLRLNFLEWYHYSFEGGGKKFQPLKLLKIE

Sequences:

>Translated_638_residues
MRKDVKKFLFLGLADEKKSFFQQAQKLGFIHFIDPCQTSNRDIPEAIEKLTTAIKILRGLPFVEQEENYQPLNSNTIVEN
ILSLCKKSEKKQEEIRVLRLEMSRIEIFGNFSLEDIYFIENAGKRKIQFFVARSSAFKEQDPPDELIYISSNQGLDYYFA
INEQSVSYDKLIEIKINRSLQNLNQQLIEANSERRRIDHQLKELAKYNEFLHHALVNKLNSHHLNHAQTYVQQTMDGLLF
AVEGWVPANKVDQIEKVTKALNVYIDEVAIEASDVIPTYLENSGFSRLGEDLVNIYDTPSSSDHDPSNWVLWCFTLFFAF
IIGDAGYGFIYLALALFLRYKYPDLKGLSKRLLNLFTILCVGCIVWGTLMTSFFGMQIDINNPIRKISLVQWLSKEKIAY
HIAHQDSTYQKWLQAYPTLANHADAHEFVSFIPDWEPSKGPVILSMISDTIMFELALFIGVVHLLLSLLRYGLRNIPNLG
WAAFLIGAYLYFPSHLQAPSFLNFIGNVDLNEGGKIGLQFMIGGIAFAWITSIWKNGWTGIFEITVLIQVFADVLSYLRL
YALALAGAVVGATVNEIASGLPLLASFFLVMIAHFVNLILGTMGGVIHGLRLNFLEWYHYSFEGGGKKFQPLKLLKIE
>Mature_638_residues
MRKDVKKFLFLGLADEKKSFFQQAQKLGFIHFIDPCQTSNRDIPEAIEKLTTAIKILRGLPFVEQEENYQPLNSNTIVEN
ILSLCKKSEKKQEEIRVLRLEMSRIEIFGNFSLEDIYFIENAGKRKIQFFVARSSAFKEQDPPDELIYISSNQGLDYYFA
INEQSVSYDKLIEIKINRSLQNLNQQLIEANSERRRIDHQLKELAKYNEFLHHALVNKLNSHHLNHAQTYVQQTMDGLLF
AVEGWVPANKVDQIEKVTKALNVYIDEVAIEASDVIPTYLENSGFSRLGEDLVNIYDTPSSSDHDPSNWVLWCFTLFFAF
IIGDAGYGFIYLALALFLRYKYPDLKGLSKRLLNLFTILCVGCIVWGTLMTSFFGMQIDINNPIRKISLVQWLSKEKIAY
HIAHQDSTYQKWLQAYPTLANHADAHEFVSFIPDWEPSKGPVILSMISDTIMFELALFIGVVHLLLSLLRYGLRNIPNLG
WAAFLIGAYLYFPSHLQAPSFLNFIGNVDLNEGGKIGLQFMIGGIAFAWITSIWKNGWTGIFEITVLIQVFADVLSYLRL
YALALAGAVVGATVNEIASGLPLLASFFLVMIAHFVNLILGTMGGVIHGLRLNFLEWYHYSFEGGGKKFQPLKLLKIE

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG1269

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit I

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the V-ATPase 116 kDa subunit family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002490 [H]

Pfam domain/function: PF01496 V_ATPase_I [H]

EC number: 3.6.3.14

Molecular weight: Translated: 72739; Mature: 72739

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKDVKKFLFLGLADEKKSFFQQAQKLGFIHFIDPCQTSNRDIPEAIEKLTTAIKILRGL
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PFVEQEENYQPLNSNTIVENILSLCKKSEKKQEEIRVLRLEMSRIEIFGNFSLEDIYFIE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEE
NAGKRKIQFFVARSSAFKEQDPPDELIYISSNQGLDYYFAINEQSVSYDKLIEIKINRSL
CCCCCEEEEEEEHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHEEEEEECHHH
QNLNQQLIEANSERRRIDHQLKELAKYNEFLHHALVNKLNSHHLNHAQTYVQQTMDGLLF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AVEGWVPANKVDQIEKVTKALNVYIDEVAIEASDVIPTYLENSGFSRLGEDLVNIYDTPS
HEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCC
SSDHDPSNWVLWCFTLFFAFIIGDAGYGFIYLALALFLRYKYPDLKGLSKRLLNLFTILC
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGCIVWGTLMTSFFGMQIDINNPIRKISLVQWLSKEKIAYHIAHQDSTYQKWLQAYPTLA
HHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCHH
NHADAHEFVSFIPDWEPSKGPVILSMISDTIMFELALFIGVVHLLLSLLRYGLRNIPNLG
CCCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WAAFLIGAYLYFPSHLQAPSFLNFIGNVDLNEGGKIGLQFMIGGIAFAWITSIWKNGWTG
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
IFEITVLIQVFADVLSYLRLYALALAGAVVGATVNEIASGLPLLASFFLVMIAHFVNLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GTMGGVIHGLRLNFLEWYHYSFEGGGKKFQPLKLLKIE
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECC
>Mature Secondary Structure
MRKDVKKFLFLGLADEKKSFFQQAQKLGFIHFIDPCQTSNRDIPEAIEKLTTAIKILRGL
CCHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCC
PFVEQEENYQPLNSNTIVENILSLCKKSEKKQEEIRVLRLEMSRIEIFGNFSLEDIYFIE
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEE
NAGKRKIQFFVARSSAFKEQDPPDELIYISSNQGLDYYFAINEQSVSYDKLIEIKINRSL
CCCCCEEEEEEEHHHHCCCCCCCCCEEEEECCCCCEEEEEECCCCCCHHHEEEEEECHHH
QNLNQQLIEANSERRRIDHQLKELAKYNEFLHHALVNKLNSHHLNHAQTYVQQTMDGLLF
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
AVEGWVPANKVDQIEKVTKALNVYIDEVAIEASDVIPTYLENSGFSRLGEDLVNIYDTPS
HEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHCCCC
SSDHDPSNWVLWCFTLFFAFIIGDAGYGFIYLALALFLRYKYPDLKGLSKRLLNLFTILC
CCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
VGCIVWGTLMTSFFGMQIDINNPIRKISLVQWLSKEKIAYHIAHQDSTYQKWLQAYPTLA
HHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHCCCHH
NHADAHEFVSFIPDWEPSKGPVILSMISDTIMFELALFIGVVHLLLSLLRYGLRNIPNLG
CCCCHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
WAAFLIGAYLYFPSHLQAPSFLNFIGNVDLNEGGKIGLQFMIGGIAFAWITSIWKNGWTG
HHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
IFEITVLIQVFADVLSYLRLYALALAGAVVGATVNEIASGLPLLASFFLVMIAHFVNLIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
GTMGGVIHGLRLNFLEWYHYSFEGGGKKFQPLKLLKIE
HHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]