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The map label for this gene is menC [H]

Identifier: 46447297

GI number: 46447297

Start: 2000914

End: 2001852

Strand: Reverse

Name: menC [H]

Synonym: pc1663

Alternate gene names: 46447297

Gene position: 2001852-2000914 (Counterclockwise)

Preceding gene: 46447298

Following gene: 46447295

Centisome position: 82.91

GC content: 33.65

Gene sequence:

>939_bases
ATGAAATTCGAAAAATTTATTTGCAATCTTCGGCAATTTACACTCACTAATGGATTAAAAAGATCTATTGCGATTATTTC
TTTAGTTGATAAAAAAGGAAATATCTCAAAAGGAGAAGTCGCCCCATTACCCCCTTGGAGCAAAGAAACCTTAGAAGAGG
CTATTCGCCAAATTGATGCCAAAAAAAGCTTTATTTTAAATATAGATTGGACAATTGAAAATTATAGAGATGCATTAATG
CATCTTCATCTTTTTCCCTCGGTACAATTTGGAATAGAATCGGCTCTTCTATCCTTTTTAGATCCTTTAAAAACATATTC
TATACCAGTAAGCGCCTTATTGATGGGATCCAAAAAAGAAATTCTTGCTCAAGCAAAACTTCGCCTACAAGAAGGTTATC
AAATAGCTAAACTTAAAGTCAGCCAACTTTCGTTCTCCGATGCTGCAAAGCTTATTCACCAATTAAAAGATACTTTTCGT
TTAAGAATAGATGTTAATCGAGCCTGGAAAACGGAAGATTCTTTACAATTCTTTTCAGAATATTCTTTAGATAGTTTTGA
TTATGTTGAAGAGCCTTTTCAAAACCCTAAAGAATTATCTCTTTTTTCTCATCCCCTTGCTGTTGATGAGTCTTTTCCTT
CAAATTTTTCTCTTCAAGATTTAGAAACTTTATGCTCTCTTAAATCTCTTATTTATAAACCCACTCTACAAGGGGGAATG
ACAACTTGTTTGCCTGTATATAAATGGGCCAAACAACGCAATATTGAATTCGTTCTAAGTAGTAGTTTTGAAAGTGAATT
GGGACTCTCCCACCTCATTTCAATGGCTGCAAGATTAAAGCTGACTTCACCTATAGGAATTGGCACCTATCATTTTTTGC
CTCAAACGGAAGGTCCTTTTCTTATTTCAAATGGACAGGTTAACTTAAAAAATTTGTAA

Upstream 100 bases:

>100_bases
AAATTAAAAAAGAAAACATTGATAAATAGTTTCTTGCGTAATTATTCTATCTGCCTGTTAAAATTGGTTTTTAAAAAAAG
CTCGTGATGTAAAAGGTCTA

Downstream 100 bases:

>100_bases
CTAATCAGTAAGCTTTATTTGAAAAAAATAAAAGATAAACGCAATTTAAAATTTTTGTGGGTAAATTCTAGTCAAAAATT
TAAGTTGAATTATTTTTGAT

Product: putative o-succinylbenzoate synthase II, menC

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MKFEKFICNLRQFTLTNGLKRSIAIISLVDKKGNISKGEVAPLPPWSKETLEEAIRQIDAKKSFILNIDWTIENYRDALM
HLHLFPSVQFGIESALLSFLDPLKTYSIPVSALLMGSKKEILAQAKLRLQEGYQIAKLKVSQLSFSDAAKLIHQLKDTFR
LRIDVNRAWKTEDSLQFFSEYSLDSFDYVEEPFQNPKELSLFSHPLAVDESFPSNFSLQDLETLCSLKSLIYKPTLQGGM
TTCLPVYKWAKQRNIEFVLSSSFESELGLSHLISMAARLKLTSPIGIGTYHFLPQTEGPFLISNGQVNLKNL

Sequences:

>Translated_312_residues
MKFEKFICNLRQFTLTNGLKRSIAIISLVDKKGNISKGEVAPLPPWSKETLEEAIRQIDAKKSFILNIDWTIENYRDALM
HLHLFPSVQFGIESALLSFLDPLKTYSIPVSALLMGSKKEILAQAKLRLQEGYQIAKLKVSQLSFSDAAKLIHQLKDTFR
LRIDVNRAWKTEDSLQFFSEYSLDSFDYVEEPFQNPKELSLFSHPLAVDESFPSNFSLQDLETLCSLKSLIYKPTLQGGM
TTCLPVYKWAKQRNIEFVLSSSFESELGLSHLISMAARLKLTSPIGIGTYHFLPQTEGPFLISNGQVNLKNL
>Mature_312_residues
MKFEKFICNLRQFTLTNGLKRSIAIISLVDKKGNISKGEVAPLPPWSKETLEEAIRQIDAKKSFILNIDWTIENYRDALM
HLHLFPSVQFGIESALLSFLDPLKTYSIPVSALLMGSKKEILAQAKLRLQEGYQIAKLKVSQLSFSDAAKLIHQLKDTFR
LRIDVNRAWKTEDSLQFFSEYSLDSFDYVEEPFQNPKELSLFSHPLAVDESFPSNFSLQDLETLCSLKSLIYKPTLQGGM
TTCLPVYKWAKQRNIEFVLSSSFESELGLSHLISMAARLKLTSPIGIGTYHFLPQTEGPFLISNGQVNLKNL

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=265, Percent_Identity=27.1698113207547, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR001354
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 35417; Mature: 35417

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFEKFICNLRQFTLTNGLKRSIAIISLVDKKGNISKGEVAPLPPWSKETLEEAIRQIDA
CCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KKSFILNIDWTIENYRDALMHLHLFPSVQFGIESALLSFLDPLKTYSIPVSALLMGSKKE
CCEEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
ILAQAKLRLQEGYQIAKLKVSQLSFSDAAKLIHQLKDTFRLRIDVNRAWKTEDSLQFFSE
HHHHHHHHHHCCCEEEEEEHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHH
YSLDSFDYVEEPFQNPKELSLFSHPLAVDESFPSNFSLQDLETLCSLKSLIYKPTLQGGM
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TTCLPVYKWAKQRNIEFVLSSSFESELGLSHLISMAARLKLTSPIGIGTYHFLPQTEGPF
HHHHHHHHHHHHCCEEEEEECCCHHHCCHHHHHHHHHHHEECCCCCCCEEEECCCCCCCE
LISNGQVNLKNL
EEECCEEEECCC
>Mature Secondary Structure
MKFEKFICNLRQFTLTNGLKRSIAIISLVDKKGNISKGEVAPLPPWSKETLEEAIRQIDA
CCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCC
KKSFILNIDWTIENYRDALMHLHLFPSVQFGIESALLSFLDPLKTYSIPVSALLMGSKKE
CCEEEEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHH
ILAQAKLRLQEGYQIAKLKVSQLSFSDAAKLIHQLKDTFRLRIDVNRAWKTEDSLQFFSE
HHHHHHHHHHCCCEEEEEEHHHCCHHHHHHHHHHHHHHEEEEEEECCCCCCHHHHHHHHH
YSLDSFDYVEEPFQNPKELSLFSHPLAVDESFPSNFSLQDLETLCSLKSLIYKPTLQGGM
CCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TTCLPVYKWAKQRNIEFVLSSSFESELGLSHLISMAARLKLTSPIGIGTYHFLPQTEGPF
HHHHHHHHHHHHCCEEEEEECCCHHHCCHHHHHHHHHHHEECCCCCCCEEEECCCCCCCE
LISNGQVNLKNL
EEECCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]