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The map label for this gene is nqrF [H]

Identifier: 46447167

GI number: 46447167

Start: 1835745

End: 1837142

Strand: Reverse

Name: nqrF [H]

Synonym: pc1533

Alternate gene names: 46447167

Gene position: 1837142-1835745 (Counterclockwise)

Preceding gene: 46447177

Following gene: 46447165

Centisome position: 76.09

GC content: 35.05

Gene sequence:

>1398_bases
ATGATAAATTACTTTTTTTTTCTAGATACTGTTTTCGCTTTCCGATGTTTATTTCAGCTCACTATTCCCGAAAAAATATT
GCCGATTGTTGTTGCTGATTCTGGAGGATTTGATCCTGTTTTAAGTTTATATGCAATTGCTGCTTTTGTGTTGATAGGTG
TCGGTTTAACAGCTTTAATACTTTTTACAAAGGCCAAGTTTGTTAACTCTGAAACGTGTACAATTAAAATCAATCAAGAT
GATGCTTTAACTATTCATACTCCGGGAGGAGGAACGCTTCTTCATGCTTTGACCTCTCATGGTATTCCCATTCCTTGCCC
ATGTGGGGGAAAAGCAACTTGCAAACAGTGTCGAGTTCAAATCCTTGAAGGAGCTAGTGTTCCTTTACAAACTGATATGG
ATACATTTTCAAAAAAACAACTGAATGATGGTTGGCGCCTCTCCTGTCAATCCAAATTAAAAAGGGATTTACAAGTTCAA
GTTGATGAGCATGCCTTAGGAGTTAAAGAATGGGTAGCAACAGTTTTAAGTAATGATAATGTTGCTACTTTTATTAAAGA
GTTAATTGTTGAAATTCCCGAAGGAGAAGAAGTTCCTTATCAATCGGGAGGATATTTACAATTTCATGTTCCTTCTTTCA
AAACAAATACAGAAAATTGGAAAACAACGATGAACCCCAAATATTATGCCGATTGGGAAAAATTTGGCTTATTTGGTAAA
GAAATTGACTTTTCCCATTTACCTCAAAAACCCAATGAAGTCATAAGAGCTTACTCGATGGCGTCTTATCCTGCGGAGGG
ACGGAAGTTAATTTTTAATATTCGTATTGCAACACCACCTTTTGTAAATGGAAAAATGCAAAATGATGTTCCTTGGGGCA
TTTGTTCATCTTATGCGTTTGGTTTAAAACCTGGAGATAAAATTCGTTTGTCTGGTCCTTATGGAGAATCGTTCATGATT
CATGATGAGCGAGAATTGGTTTTCTTAATTGGAGGTGCTGGTTCTTCTTTTGGGAGAAGCCACATTCTTCATTTATTCAA
TACTGTAAAAACCTCAAGAAAACTAACCATGTGGTATGGAGCAAGATCTTTAAAAGAAAATATTTATCAAAATGAATATG
AAAAATTAGAAAAAGAGTATGCTAATTTTGCTTATCGATTAGTTTTATCAGAACCACTCCCAGAAGATTTAGAAAAAGGC
TGGCCAGCCAAGGATCCTATCAAAACAAACTTTCTTTTTAAAGCTTTTGAAGAAGGACAGCTTAAAAAGATGGATTATCC
AGAAGAATCTTTATTTTATGTTTGCGGCCCTCCAATGCACAATAAAAGTGTGCTTAAATTATTAGATGAGTATGGAGTTC
CGCGAGAAAATATTATTTTAGATGATTTTGGGAGTTGA

Upstream 100 bases:

>100_bases
TTTTTATTGCTGGGAAAATACTAGCAGATTATACCTTGTATAATATAATGACTGAGGGTAGAAATAAATCATTTAACATT
TTGTTGATCTGTAGGATTGC

Downstream 100 bases:

>100_bases
AACACTTATTAAGGCAACTTTAACTTTTTAGTCTAGGCTGCTTGGCGGACTTTCTGGAGTTTTCCGGATTGATCTGCAAG
GTATTTTCAGTTTTCCGCTT

Product: Na(+)-translocating NADH-quinone reductase subunit F

Products: NA

Alternate protein names: Na(+)-NQR subunit F; Na(+)-translocating NQR subunit F; NQR complex subunit F; NQR-1 subunit F [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MINYFFFLDTVFAFRCLFQLTIPEKILPIVVADSGGFDPVLSLYAIAAFVLIGVGLTALILFTKAKFVNSETCTIKINQD
DALTIHTPGGGTLLHALTSHGIPIPCPCGGKATCKQCRVQILEGASVPLQTDMDTFSKKQLNDGWRLSCQSKLKRDLQVQ
VDEHALGVKEWVATVLSNDNVATFIKELIVEIPEGEEVPYQSGGYLQFHVPSFKTNTENWKTTMNPKYYADWEKFGLFGK
EIDFSHLPQKPNEVIRAYSMASYPAEGRKLIFNIRIATPPFVNGKMQNDVPWGICSSYAFGLKPGDKIRLSGPYGESFMI
HDERELVFLIGGAGSSFGRSHILHLFNTVKTSRKLTMWYGARSLKENIYQNEYEKLEKEYANFAYRLVLSEPLPEDLEKG
WPAKDPIKTNFLFKAFEEGQLKKMDYPEESLFYVCGPPMHNKSVLKLLDEYGVPRENIILDDFGS

Sequences:

>Translated_465_residues
MINYFFFLDTVFAFRCLFQLTIPEKILPIVVADSGGFDPVLSLYAIAAFVLIGVGLTALILFTKAKFVNSETCTIKINQD
DALTIHTPGGGTLLHALTSHGIPIPCPCGGKATCKQCRVQILEGASVPLQTDMDTFSKKQLNDGWRLSCQSKLKRDLQVQ
VDEHALGVKEWVATVLSNDNVATFIKELIVEIPEGEEVPYQSGGYLQFHVPSFKTNTENWKTTMNPKYYADWEKFGLFGK
EIDFSHLPQKPNEVIRAYSMASYPAEGRKLIFNIRIATPPFVNGKMQNDVPWGICSSYAFGLKPGDKIRLSGPYGESFMI
HDERELVFLIGGAGSSFGRSHILHLFNTVKTSRKLTMWYGARSLKENIYQNEYEKLEKEYANFAYRLVLSEPLPEDLEKG
WPAKDPIKTNFLFKAFEEGQLKKMDYPEESLFYVCGPPMHNKSVLKLLDEYGVPRENIILDDFGS
>Mature_465_residues
MINYFFFLDTVFAFRCLFQLTIPEKILPIVVADSGGFDPVLSLYAIAAFVLIGVGLTALILFTKAKFVNSETCTIKINQD
DALTIHTPGGGTLLHALTSHGIPIPCPCGGKATCKQCRVQILEGASVPLQTDMDTFSKKQLNDGWRLSCQSKLKRDLQVQ
VDEHALGVKEWVATVLSNDNVATFIKELIVEIPEGEEVPYQSGGYLQFHVPSFKTNTENWKTTMNPKYYADWEKFGLFGK
EIDFSHLPQKPNEVIRAYSMASYPAEGRKLIFNIRIATPPFVNGKMQNDVPWGICSSYAFGLKPGDKIRLSGPYGESFMI
HDERELVFLIGGAGSSFGRSHILHLFNTVKTSRKLTMWYGARSLKENIYQNEYEKLEKEYANFAYRLVLSEPLPEDLEKG
WPAKDPIKTNFLFKAFEEGQLKKMDYPEESLFYVCGPPMHNKSVLKLLDEYGVPRENIILDDFGS

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by nqrF, which accepts electrons from NADH and reduces

COG id: COG2871

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF

Gene ontology:

Cell location: Cell inner membrane (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR010205
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 52427; Mature: 52427

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINYFFFLDTVFAFRCLFQLTIPEKILPIVVADSGGFDPVLSLYAIAAFVLIGVGLTALI
CCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFTKAKFVNSETCTIKINQDDALTIHTPGGGTLLHALTSHGIPIPCPCGGKATCKQCRVQ
HHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ILEGASVPLQTDMDTFSKKQLNDGWRLSCQSKLKRDLQVQVDEHALGVKEWVATVLSNDN
HHCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHCCCCCEEEEHHHHCCHHHHHHHHHCCCC
VATFIKELIVEIPEGEEVPYQSGGYLQFHVPSFKTNTENWKTTMNPKYYADWEKFGLFGK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCEEECHHHHCCCCC
EIDFSHLPQKPNEVIRAYSMASYPAEGRKLIFNIRIATPPFVNGKMQNDVPWGICSSYAF
CCCHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHCCCC
GLKPGDKIRLSGPYGESFMIHDERELVFLIGGAGSSFGRSHILHLFNTVKTSRKLTMWYG
CCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEC
ARSLKENIYQNEYEKLEKEYANFAYRLVLSEPLPEDLEKGWPAKDPIKTNFLFKAFEEGQ
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHCCCC
LKKMDYPEESLFYVCGPPMHNKSVLKLLDEYGVPRENIILDDFGS
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCC
>Mature Secondary Structure
MINYFFFLDTVFAFRCLFQLTIPEKILPIVVADSGGFDPVLSLYAIAAFVLIGVGLTALI
CCEEEHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
LFTKAKFVNSETCTIKINQDDALTIHTPGGGTLLHALTSHGIPIPCPCGGKATCKQCRVQ
HHHHHHHCCCCEEEEEECCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ILEGASVPLQTDMDTFSKKQLNDGWRLSCQSKLKRDLQVQVDEHALGVKEWVATVLSNDN
HHCCCCCCCCCCHHHHHHHHCCCCCEEEHHHHCCCCCEEEEHHHHCCHHHHHHHHHCCCC
VATFIKELIVEIPEGEEVPYQSGGYLQFHVPSFKTNTENWKTTMNPKYYADWEKFGLFGK
HHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEEECCCCEEECHHHHCCCCC
EIDFSHLPQKPNEVIRAYSMASYPAEGRKLIFNIRIATPPFVNGKMQNDVPWGICSSYAF
CCCHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCHHHHCCCC
GLKPGDKIRLSGPYGESFMIHDERELVFLIGGAGSSFGRSHILHLFNTVKTSRKLTMWYG
CCCCCCEEEEECCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEC
ARSLKENIYQNEYEKLEKEYANFAYRLVLSEPLPEDLEKGWPAKDPIKTNFLFKAFEEGQ
HHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHCCCCCCCCCCCCHHHHHHCCCC
LKKMDYPEESLFYVCGPPMHNKSVLKLLDEYGVPRENIILDDFGS
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12682364 [H]