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The map label for this gene is ackA

Identifier: 46446996

GI number: 46446996

Start: 1628686

End: 1629873

Strand: Reverse

Name: ackA

Synonym: pc1362

Alternate gene names: 46446996

Gene position: 1629873-1628686 (Counterclockwise)

Preceding gene: 46446998

Following gene: 46446991

Centisome position: 67.5

GC content: 35.77

Gene sequence:

>1188_bases
ATGCCGAAGGTACTGGTGATGAATGCAGGTTCAAGCTCGCATAAACTTTCGCTTTTTAGTGATAAAATTGAGAATGCCGG
ATCAGCTTTATGGAAAGCTCATATAGAATGGGGAAAAAAAAATCCTAGTTATACTTTGAAAAACGGAAGCCAAGAGTCCA
ATCCCATTTATTTGCAAACAACTTCAGTTAAACAAGGGATCCAAGAAGTGATAGAAAAGTTGTGGATAGGAGATTTTGCT
GTCATTAAAGAAGTGCATGAGATTGAATGGATTGGGCATCGCGTTGTTCATGGAGGTTCTTTATTCCATCAGCCTGTTTT
GATCAATGCATCGGTAAAAAAAGACATTAGCAATTTAAGTTCTTTAGCCCCTTTACATAATCCTATCAATTTAGAGGGGA
TTGAATTATTAGAAAAAATATTTCCCTCGATTCCTCATTTTGCCGTTTTTGATACTGCTTTTCACCGGACAATGCGTGAA
GAGATTAAAACCTATCCTATTCCTTATGAATGGAAGGAAAAGGGGATTGAACGTTATGGTTTTCATGGAATAAGTCATTC
TTACTGTGCAAAACAAATAAAAAAATGGATAAAGCCTCAAGAAACTCCTTTTAAGCTTATTAATTGTCATTTAGGAAATG
GAGCATCTCTTTGTGCGATACGAGATGGGTTCAGCATAGATACAACCATGGGATTTACTCCGATGGAAGGTTTGATGATG
GGGACTCGATCAGGTTCTATTGATCCCGGCATTTTGATTTACTGTTTGAGAAATAAAAATCTTTCCTTAGAAGAACTCGA
TCATCTTTTAAATTTTGAATCGGGATTAAAAGGAATTGGAGGAACTTCTGATATGAGAGAGATTCATGCTTTTAAAAATA
AGCAGTCACAGCTGGCTCTAGATATGTATATTTATCGTTTAAAAACTGGAATAGGAGCTATGACAGCTTCTCTTGGAGGA
ATTGATGCTTTGTGTTTTACAGGTGGAATTGGAGAAAATGATAGTTATCTTCGAAAAAAAACTTGTGAAGAATTAGCTTA
TCTTGGCATTCAACTGGATTTGCAAAAAAATCAAGGGGGGAATCAGGATAAAGAAATTAGTTTGCATGATTCACCTGTCA
AAGTTTTCGTCATTCATACACAAGAAGAATGGATGATTGCTAAATCTTGCTTAGAGTATTTGACTTGA

Upstream 100 bases:

>100_bases
GAATAGATGAAAAAAGAATGCCAAAACAGCCTCTTTACAAAAATAAATTTCCTGATAGCTTGAATTTAGAGTTTTATTTT
TTCCAAATTTAGGAGTCAGC

Downstream 100 bases:

>100_bases
GGTTAAAAATTCAGAAATTGAGCGTTGAATAAGTTCTCGATTCACCCTAGCAACATCTTGAAGAAATGTAAGACGATTGA
TTTGAAGAGAAATTTTTTGA

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MPKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQTTSVKQGIQEVIEKLWIGDFA
VIKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLSSLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMRE
EIKTYPIPYEWKEKGIERYGFHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMM
GTRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLALDMYIYRLKTGIGAMTASLGG
IDALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGGNQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT

Sequences:

>Translated_395_residues
MPKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQTTSVKQGIQEVIEKLWIGDFA
VIKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLSSLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMRE
EIKTYPIPYEWKEKGIERYGFHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMM
GTRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLALDMYIYRLKTGIGAMTASLGG
IDALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGGNQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT
>Mature_394_residues
PKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQTTSVKQGIQEVIEKLWIGDFAV
IKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLSSLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMREE
IKTYPIPYEWKEKGIERYGFHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMMG
TRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLALDMYIYRLKTGIGAMTASLGGI
DALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGGNQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=394, Percent_Identity=38.8324873096447, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1788633, Length=406, Percent_Identity=38.6699507389163, Blast_Score=241, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_PARUW (Q6MBG3)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008361.1
- HSSP:   P38502
- ProteinModelPortal:   Q6MBG3
- SMR:   Q6MBG3
- STRING:   Q6MBG3
- GeneID:   2781315
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1362
- NMPDR:   fig|264201.1.peg.1362
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   LVERISM
- PhylomeDB:   Q6MBG3
- BioCyc:   CPRO264201:PC1362-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 44254; Mature: 44122

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQT
CCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEE
TSVKQGIQEVIEKLWIGDFAVIKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCHHCCCEEEECHHHHHHHHHH
SLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMREEIKTYPIPYEWKEKGIERYG
HHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHC
FHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMM
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCEECCCCCCCCHHHHEE
GTRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLAL
ECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHH
DMYIYRLKTGIGAMTASLGGIDALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGG
HHHHHHHHHCHHHHHHHCCCCEEHEEECCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCC
NQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT
CCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PKVLVMNAGSSSHKLSLFSDKIENAGSALWKAHIEWGKKNPSYTLKNGSQESNPIYLQT
CCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCEEEEE
TSVKQGIQEVIEKLWIGDFAVIKEVHEIEWIGHRVVHGGSLFHQPVLINASVKKDISNLS
CHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHEEECCCHHCCCEEEECHHHHHHHHHH
SLAPLHNPINLEGIELLEKIFPSIPHFAVFDTAFHRTMREEIKTYPIPYEWKEKGIERYG
HHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCHHHHC
FHGISHSYCAKQIKKWIKPQETPFKLINCHLGNGASLCAIRDGFSIDTTMGFTPMEGLMM
CCCCCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEEECCCEECCCCCCCCHHHHEE
GTRSGSIDPGILIYCLRNKNLSLEELDHLLNFESGLKGIGGTSDMREIHAFKNKQSQLAL
ECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHH
DMYIYRLKTGIGAMTASLGGIDALCFTGGIGENDSYLRKKTCEELAYLGIQLDLQKNQGG
HHHHHHHHHCHHHHHHHCCCCEEHEEECCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCC
NQDKEISLHDSPVKVFVIHTQEEWMIAKSCLEYLT
CCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA