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The map label for this gene is efp

Identifier: 46446403

GI number: 46446403

Start: 951347

End: 951901

Strand: Direct

Name: efp

Synonym: pc0769

Alternate gene names: 46446403

Gene position: 951347-951901 (Clockwise)

Preceding gene: 46446402

Following gene: 46446404

Centisome position: 39.4

GC content: 35.14

Gene sequence:

>555_bases
ATGGCGACAAGTAATCAATTGACTCCAGGAATGACACTTTCCATTAACAACAAACTTTATCGTGTTGAATCCAGCGTAAA
AGTAACAGTTCCTAAAGGGACTCCTTTTATTAAAGCTAAACTAAAAGATTTGAGCAATAATGAAATGGTTGAAAAAAGCT
TTAAGCTGAATCAACCGATTAAAGATGTGTCATTAATTGAACGTCGCTTAGAGTTCCTTTATCCTGAAGGAGATGAGTAT
CTTTTTTTGGATGTTGTTAATTTAGACCAGGTCCTCGTTCCAGCTGAAATCGTGAGTGGCAAAGTTAATTATCTCAAAGA
AGGGGTCGAAATTAAAGCTTTTTTTTATGGAGAAACAATCTTTGCTGTCGAGCTTCCGCAGTTTTTAGAATTAATGGTTG
CTAAAACGCATTCGGATGACGAAAATGATCTAGCTAATGGAGCAAAAATTGCCATTTTAGAAACAGGGGCAAAAATTGAA
GTTCCACCTTTTATTGAAACAGGAGATATTATCAAAGTTGACACTAAAACTGACGAATATATTCAACGTGTTTGA

Upstream 100 bases:

>100_bases
TTTAAATCTCCAAACTTTGCCGATGCAATAAAGCAAATGCGGCAGTCTGCCGAAGGTCATTAAAAAATTAATAAATTGTT
AACAGATAACTGTAGGAATT

Downstream 100 bases:

>100_bases
TATTTAAAAGTGAAAATTAAGGGAAGGATAATCAAGTGCTTATGATAAAGATAAACAGGATCCATTCATTGATTATCGAG
TTTATATTAAGTCTAAATGA

Product: elongation factor P

Products: NA

Alternate protein names: EF-P 1

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MATSNQLTPGMTLSINNKLYRVESSVKVTVPKGTPFIKAKLKDLSNNEMVEKSFKLNQPIKDVSLIERRLEFLYPEGDEY
LFLDVVNLDQVLVPAEIVSGKVNYLKEGVEIKAFFYGETIFAVELPQFLELMVAKTHSDDENDLANGAKIAILETGAKIE
VPPFIETGDIIKVDTKTDEYIQRV

Sequences:

>Translated_184_residues
MATSNQLTPGMTLSINNKLYRVESSVKVTVPKGTPFIKAKLKDLSNNEMVEKSFKLNQPIKDVSLIERRLEFLYPEGDEY
LFLDVVNLDQVLVPAEIVSGKVNYLKEGVEIKAFFYGETIFAVELPQFLELMVAKTHSDDENDLANGAKIAILETGAKIE
VPPFIETGDIIKVDTKTDEYIQRV
>Mature_183_residues
ATSNQLTPGMTLSINNKLYRVESSVKVTVPKGTPFIKAKLKDLSNNEMVEKSFKLNQPIKDVSLIERRLEFLYPEGDEYL
FLDVVNLDQVLVPAEIVSGKVNYLKEGVEIKAFFYGETIFAVELPQFLELMVAKTHSDDENDLANGAKIAILETGAKIEV
PPFIETGDIIKVDTKTDEYIQRV

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=187, Percent_Identity=31.5508021390374, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=25.3968253968254, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP1_PARUW (Q6MD56)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007768.1
- ProteinModelPortal:   Q6MD56
- SMR:   Q6MD56
- STRING:   Q6MD56
- GeneID:   2779455
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0769
- NMPDR:   fig|264201.1.peg.769
- eggNOG:   COG0231
- HOGENOM:   HBG303311
- OMA:   LELMVSK
- ProtClustDB:   PRK12426
- BioCyc:   CPRO264201:PC0769-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20672; Mature: 20541

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATSNQLTPGMTLSINNKLYRVESSVKVTVPKGTPFIKAKLKDLSNNEMVEKSFKLNQPI
CCCCCCCCCCEEEEECCEEEEEECCEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCCH
KDVSLIERRLEFLYPEGDEYLFLDVVNLDQVLVPAEIVSGKVNYLKEGVEIKAFFYGETI
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEECHHHHCCHHHHHHCCCEEEEEEECCEE
FAVELPQFLELMVAKTHSDDENDLANGAKIAILETGAKIEVPPFIETGDIIKVDTKTDEY
EEEECHHHHHHHHHHCCCCCCCHHCCCEEEEEEECCCEEECCCCCCCCCEEEEECCCHHH
IQRV
HHCC
>Mature Secondary Structure 
ATSNQLTPGMTLSINNKLYRVESSVKVTVPKGTPFIKAKLKDLSNNEMVEKSFKLNQPI
CCCCCCCCCEEEEECCEEEEEECCEEEEECCCCCEEEEEECCCCCCHHHHHHHCCCCCH
KDVSLIERRLEFLYPEGDEYLFLDVVNLDQVLVPAEIVSGKVNYLKEGVEIKAFFYGETI
HHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEECHHHHCCHHHHHHCCCEEEEEEECCEE
FAVELPQFLELMVAKTHSDDENDLANGAKIAILETGAKIEVPPFIETGDIIKVDTKTDEY
EEEECHHHHHHHHHHCCCCCCCHHCCCEEEEEEECCCEEECCCCCCCCCEEEEECCCHHH
IQRV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA