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The map label for this gene is rpe [H]

Identifier: 46446402

GI number: 46446402

Start: 950578

End: 951309

Strand: Direct

Name: rpe [H]

Synonym: pc0768

Alternate gene names: 46446402

Gene position: 950578-951309 (Clockwise)

Preceding gene: 46446400

Following gene: 46446403

Centisome position: 39.37

GC content: 38.66

Gene sequence:

>732_bases
ATGAAAAGAGAACCGCAAGCTGTTAAAATTGCTCCATCGATTTTAGCGGGAGATTTCGGGCATCTAGCAGATGAAGCTAA
AAAAGCTGAGCAAGCAGGAGCAGACTCACTGCACTTAGATATTATGGATGGACATTTCGTTCCGAATTTAACGATGGGTT
CTCAAGCAGTCTCTGCTATCAATCGAGCAACAAATTTGTTTTTAGATGTTCATTTAATGATTTATAACCCATTTGACTAC
ATTGAACGTTTTGTCCAAGCTGGAGCTGATAGTATTACTTTTCATATGGAAGCAACAGAAGATGTAGAAGAAACACTGGC
TTATATTCGAAAATGTAATATACGAGCAGGTTTGGCATTCAATCCAGAAACATCTGTTTCTATGATACCTAAATATTTAG
ATAAATGTGATATGATTCTCTTGATGACTGTCAATCCAGGTTTTGGAGGACAAAAATTTATCGAAAAAGTGCTAGACAAA
GTGCAATTTACAAGGGACTTGTGTAACCAGCTTAATATTCGAGCAGGGGGAGTGACCCTTAAAGATAATTCATCAACGGG
TCATCAACTTCCTCCTTTTGATATTCAAGTCGATGGAGGGATTACTCATTTGAATGTAAGACGTTGCGTAGAAGCGGGGG
CAAATGTTATTGTGGCAGGAACAAGCCTTTTTAAATCTCCAAACTTTGCCGATGCAATAAAGCAAATGCGGCAGTCTGCC
GAAGGTCATTAA

Upstream 100 bases:

>100_bases
ATTGATATTCAATGATATTACTGTATGATCTTGGTATCATCTTGACTTTTGATCATCGAACGGAGTATGAACTTAGGTAA
TTTTAAGAAATGGATAAAAT

Downstream 100 bases:

>100_bases
AAAATTAATAAATTGTTAACAGATAACTGTAGGAATTATGGCGACAAGTAATCAATTGACTCCAGGAATGACACTTTCCA
TTAACAACAAACTTTATCGT

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKREPQAVKIAPSILAGDFGHLADEAKKAEQAGADSLHLDIMDGHFVPNLTMGSQAVSAINRATNLFLDVHLMIYNPFDY
IERFVQAGADSITFHMEATEDVEETLAYIRKCNIRAGLAFNPETSVSMIPKYLDKCDMILLMTVNPGFGGQKFIEKVLDK
VQFTRDLCNQLNIRAGGVTLKDNSSTGHQLPPFDIQVDGGITHLNVRRCVEAGANVIVAGTSLFKSPNFADAIKQMRQSA
EGH

Sequences:

>Translated_243_residues
MKREPQAVKIAPSILAGDFGHLADEAKKAEQAGADSLHLDIMDGHFVPNLTMGSQAVSAINRATNLFLDVHLMIYNPFDY
IERFVQAGADSITFHMEATEDVEETLAYIRKCNIRAGLAFNPETSVSMIPKYLDKCDMILLMTVNPGFGGQKFIEKVLDK
VQFTRDLCNQLNIRAGGVTLKDNSSTGHQLPPFDIQVDGGITHLNVRRCVEAGANVIVAGTSLFKSPNFADAIKQMRQSA
EGH
>Mature_243_residues
MKREPQAVKIAPSILAGDFGHLADEAKKAEQAGADSLHLDIMDGHFVPNLTMGSQAVSAINRATNLFLDVHLMIYNPFDY
IERFVQAGADSITFHMEATEDVEETLAYIRKCNIRAGLAFNPETSVSMIPKYLDKCDMILLMTVNPGFGGQKFIEKVLDK
VQFTRDLCNQLNIRAGGVTLKDNSSTGHQLPPFDIQVDGGITHLNVRRCVEAGANVIVAGTSLFKSPNFADAIKQMRQSA
EGH

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=231, Percent_Identity=38.961038961039, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI219879828, Length=231, Percent_Identity=36.7965367965368, Blast_Score=163, Evalue=1e-40,
Organism=Homo sapiens, GI24307923, Length=186, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-25,
Organism=Escherichia coli, GI1789788, Length=233, Percent_Identity=41.6309012875536, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1790523, Length=216, Percent_Identity=35.1851851851852, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790754, Length=225, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=237, Percent_Identity=41.3502109704641, Blast_Score=179, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6322341, Length=242, Percent_Identity=40.0826446280992, Blast_Score=176, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24586301, Length=234, Percent_Identity=38.4615384615385, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 26637; Mature: 26637

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKREPQAVKIAPSILAGDFGHLADEAKKAEQAGADSLHLDIMDGHFVPNLTMGSQAVSAI
CCCCCCEEEECHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHH
NRATNLFLDVHLMIYNPFDYIERFVQAGADSITFHMEATEDVEETLAYIRKCNIRAGLAF
HHHHHHEEEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCEEE
NPETSVSMIPKYLDKCDMILLMTVNPGFGGQKFIEKVLDKVQFTRDLCNQLNIRAGGVTL
CCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEE
KDNSSTGHQLPPFDIQVDGGITHLNVRRCVEAGANVIVAGTSLFKSPNFADAIKQMRQSA
ECCCCCCCCCCCEEEEECCCEEEHHHHHHHHHCCCEEEECHHHHCCCCHHHHHHHHHHHC
EGH
CCC
>Mature Secondary Structure
MKREPQAVKIAPSILAGDFGHLADEAKKAEQAGADSLHLDIMDGHFVPNLTMGSQAVSAI
CCCCCCEEEECHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHH
NRATNLFLDVHLMIYNPFDYIERFVQAGADSITFHMEATEDVEETLAYIRKCNIRAGLAF
HHHHHHEEEEEEEEECCHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCEEE
NPETSVSMIPKYLDKCDMILLMTVNPGFGGQKFIEKVLDKVQFTRDLCNQLNIRAGGVTL
CCCCHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCEEE
KDNSSTGHQLPPFDIQVDGGITHLNVRRCVEAGANVIVAGTSLFKSPNFADAIKQMRQSA
ECCCCCCCCCCCEEEEECCCEEEHHHHHHHHHCCCEEEECHHHHCCCCHHHHHHHHHHHC
EGH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]