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The map label for this gene is infC [H]

Identifier: 46446336

GI number: 46446336

Start: 855435

End: 855989

Strand: Direct

Name: infC [H]

Synonym: pc0702

Alternate gene names: 46446336

Gene position: 855435-855989 (Clockwise)

Preceding gene: 46446335

Following gene: 46446337

Centisome position: 35.43

GC content: 39.82

Gene sequence:

>555_bases
TTGAAAGTTAATAGAGAAATACGAGCTCCAAAAGTTCGAGTCATTGATCATTTAGGTGAACAAGTAGGGATTATTCCCTT
ATATGAAGCCTTGGCAATGGCCGAAGAACACGGATTAGACCTAGTTGAAATTGTTCCAGGGTCCAGCCCTCCCGTTTGTA
AAGTCATGAATTTTGGAAAATTCCGTTATGACCAAAGTAAACGAGAGAAGGAAAATAAAAAGGCTCAACATCAAATTAAG
GTAAAAGAAATTAAGCTTAAGCCAAATATTGATGTTCATGACCTTGAAACAAAAACAAGACATGCCCGAGACTTTTTAGC
AAGTGGTAACAAAGTTAAAGTCACTTGTACATTTCGTGGGCGAGAAATGATGCACCCAGAGATTGGAGAGAAAATCGTTC
GAGAGATGTGTCAGGAACTAGAAGATATTTCAACGCCTGAATCACCTGCGAAAATGATGGGACGCATGCTGCTTGTTGTT
TTAGCCCCTGGAGGAAAAAAGAAAAAAGAGGGAGTCAAATCAAGTGGTGGGACTGAAGAGTCTACTACCAACTAG

Upstream 100 bases:

>100_bases
GAATCAATTAGATTAGAGGAATTTTTAGAACAAATACGCCAAAAATGTGTTTGTCCAACAGTGTTGGATAATAACTATGA
AGAGGAGAGACTAGATTAGC

Downstream 100 bases:

>100_bases
ACGTAATAACTTCCTCACTGAAGAGATTTAACAATTTAGGAGAAAAGACAATGCCTAAAATGAAAACCCGCAAAGCCGTT
GCTTCTAAGTTTCGCGTGAC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKVNREIRAPKVRVIDHLGEQVGIIPLYEALAMAEEHGLDLVEIVPGSSPPVCKVMNFGKFRYDQSKREKENKKAQHQIK
VKEIKLKPNIDVHDLETKTRHARDFLASGNKVKVTCTFRGREMMHPEIGEKIVREMCQELEDISTPESPAKMMGRMLLVV
LAPGGKKKKEGVKSSGGTEESTTN

Sequences:

>Translated_184_residues
MKVNREIRAPKVRVIDHLGEQVGIIPLYEALAMAEEHGLDLVEIVPGSSPPVCKVMNFGKFRYDQSKREKENKKAQHQIK
VKEIKLKPNIDVHDLETKTRHARDFLASGNKVKVTCTFRGREMMHPEIGEKIVREMCQELEDISTPESPAKMMGRMLLVV
LAPGGKKKKEGVKSSGGTEESTTN
>Mature_184_residues
MKVNREIRAPKVRVIDHLGEQVGIIPLYEALAMAEEHGLDLVEIVPGSSPPVCKVMNFGKFRYDQSKREKENKKAQHQIK
VKEIKLKPNIDVHDLETKTRHARDFLASGNKVKVTCTFRGREMMHPEIGEKIVREMCQELEDISTPESPAKMMGRMLLVV
LAPGGKKKKEGVKSSGGTEESTTN

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=47.9041916167665, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20688; Mature: 20688

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVNREIRAPKVRVIDHLGEQVGIIPLYEALAMAEEHGLDLVEIVPGSSPPVCKVMNFGK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEHHHCCCC
FRYDQSKREKENKKAQHQIKVKEIKLKPNIDVHDLETKTRHARDFLASGNKVKVTCTFRG
CCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECC
REMMHPEIGEKIVREMCQELEDISTPESPAKMMGRMLLVVLAPGGKKKKEGVKSSGGTEE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCHHHCCCCCCCCCC
STTN
CCCC
>Mature Secondary Structure
MKVNREIRAPKVRVIDHLGEQVGIIPLYEALAMAEEHGLDLVEIVPGSSPPVCKVMNFGK
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEECCCCCCCEEHHHCCCC
FRYDQSKREKENKKAQHQIKVKEIKLKPNIDVHDLETKTRHARDFLASGNKVKVTCTFRG
CCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEEEEECC
REMMHPEIGEKIVREMCQELEDISTPESPAKMMGRMLLVVLAPGGKKKKEGVKSSGGTEE
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHEEEEECCCCCCHHHCCCCCCCCCC
STTN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]