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The map label for this gene is rnhB

Identifier: 46446292

GI number: 46446292

Start: 803632

End: 804300

Strand: Direct

Name: rnhB

Synonym: pc0658

Alternate gene names: 46446292

Gene position: 803632-804300 (Clockwise)

Preceding gene: 46446291

Following gene: 46446293

Centisome position: 33.28

GC content: 40.21

Gene sequence:

>669_bases
ATGCCTGATTTAATTTCAACAGAAGAGTTAACTCGCTTAGAACACATGATTGTGTATGAAAAGCGAGCTTTTTCGCAAGG
GTATCAACTGATTGCAGGAATTGATGAAGCGGGAAGAGGGCCTTTAGCTGGTCCTGTCGTTGCCGCTGCTTGTATTCTCC
CTAAAGGGCTTCTGGTGCCTCAGATAAATGATAGTAAAAAATTATCTCCAAAGGTTAGAGAACGTCTATTTGAACGTTTA
ACAACCGATTCTGCAGTTCGATATGGAATAGGCATTATTGGTCAAGCGGAGATAGATCGAGTAAATATTTATCAAGCCAC
TATTCTAGCTATGTTAATGGCTATTCAACAGCTTCCTGTTACACCTGATTATGTATTAGTAGATGGAATGAATTTGCCCC
ATCCGGATTTACCCTGCCTCAAAATTATCAAAGGAGATCAACTCTCTCAATCGATTGCGGCTGCTTCAATCATTGCCAAA
GAAACCAGAGATCGATTGATGTGTCAATATCATCGAGAATGGCCTGGTTATGGATTTAACCAACATAAAGGATATGCCAC
TGAGCTTCATTTAGAAGCTTTATTTAAACAAGGCCCCTGCCCCATCCATCGTCGTTCCTTTGATCCCATTAAATCCATGC
TTGAAGTCGAAATAGCTGATGATTTTTAA

Upstream 100 bases:

>100_bases
CAAATATAATCAGAGAGTTGAATTTTGCTTTGGCAAAAGCATCTTTCTGATTTGAAAAAAAATAATTTATCAATTCACTG
CCTTTTACAATTGACTTCTT

Downstream 100 bases:

>100_bases
GTTGCTATTTTATAGCTCACATTCAGTCACTATTTTAAAAATTAATATGCAGAGAACGTTATTTTTTCTTGTTAATATTA
CATAACTATTTAGTATTCAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MPDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVPQINDSKKLSPKVRERLFERL
TTDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPVTPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAK
ETRDRLMCQYHREWPGYGFNQHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF

Sequences:

>Translated_222_residues
MPDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVPQINDSKKLSPKVRERLFERL
TTDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPVTPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAK
ETRDRLMCQYHREWPGYGFNQHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF
>Mature_221_residues
PDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVPQINDSKKLSPKVRERLFERLT
TDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPVTPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAKE
TRDRLMCQYHREWPGYGFNQHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=186, Percent_Identity=47.3118279569892, Blast_Score=163, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_PARUW (Q6MDG7)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007657.1
- ProteinModelPortal:   Q6MDG7
- SMR:   Q6MDG7
- STRING:   Q6MDG7
- GeneID:   2780479
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0658
- NMPDR:   fig|264201.1.peg.658
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q6MDG7
- ProtClustDB:   PRK00015
- BioCyc:   CPRO264201:PC0658-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 24810; Mature: 24679

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC
QINDSKKLSPKVRERLFERLTTDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPV
CCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAKETRDRLMCQYHREWPGYGFN
CCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PDLISTEELTRLEHMIVYEKRAFSQGYQLIAGIDEAGRGPLAGPVVAAACILPKGLLVP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHHHCCCCCCCC
QINDSKKLSPKVRERLFERLTTDSAVRYGIGIIGQAEIDRVNIYQATILAMLMAIQQLPV
CCCCCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TPDYVLVDGMNLPHPDLPCLKIIKGDQLSQSIAAASIIAKETRDRLMCQYHREWPGYGFN
CCCEEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
QHKGYATELHLEALFKQGPCPIHRRSFDPIKSMLEVEIADDF
CCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA