Click here to switch to the map view.

The map label for this gene is pepP [H]

Identifier: 46446221

GI number: 46446221

Start: 723285

End: 724478

Strand: Direct

Name: pepP [H]

Synonym: pc0587

Alternate gene names: 46446221

Gene position: 723285-724478 (Clockwise)

Preceding gene: 46446220

Following gene: 46446223

Centisome position: 29.96

GC content: 35.68

Gene sequence:

>1194_bases
ATGGAATTTGAAAAAAAATTAATTGAAGTTCAACAACAATTAAAAAAAGAAAAGATCAATGGTTGGCTGCTTTATGATTT
TAGGCATAGTAATTCTCTAGCTTATATTTTTTTAGAGATCCCTGCTTCAAAAATGCTTTCCAGGCGTTTTTTCTATTGGA
TTCCGAGCTCAGGAGAACCCATCAAAATCGTTCCTCAAATTGAATCCCATACTCTGGATCATTTACCGGGAATAAAATGG
ATTTACAAAAGTTGGCAGGAACTAGAAAGCCAGTTGTTTTCTCTGAAACTAGAAAATCATAAAGTTGCTATGGAATATTC
TCCTTTTAATGCTTTGCCTACTCTTTCGAAAGTGGATGCAGGCACAATAGATTTCATGCGAAAAAATGGAGTAGAAGTTG
TTAGTTCGGCAAATTTTATTCAACGTTATACCTGTGTTTGGAATCCTCAACAACTTCAAAGTCATTTAGAGGCAGCTGAA
ATATTGAGCTTAATTGTAGACCAAACTTGGAATTTTATTGAGAAAAAATTAATTACTAGCCAAGCCGTTGATGAATACCA
AGTTCAGCAATTTATGCTAAAACTTATGACCGAACACAATTGTGTGACAGCAGATCCTCCCACATGCGCTATCAATGCTA
ATTCTGCTGATCCCCACTACAGCCCTAAAAAAGGTCAGGCATTGTCTATTCGACCTGGAGACTTCATCTTATTAGATCTT
TGGTGCAAAAAAAATCAACCAAACTCTGTTTATGCAGATATTACAAGAGTTGGTGTGGCTGCAAAAAATGCACAAATAAA
ACAAAAACATATTTTTAATCTTGTAAAAGAAACTCGAGATCGAGCAACTCTTTTTATTAAAGAAAATTATGAAGCAGGCC
TTTCTATTCAGGGTTGGCAAGTTGATCAACTGTGTAGAGATGTGCTAAATGAAAAAGGGTATGGTGAATATTTTATTCAT
CGAACTGGGCACAATATCGGACAAGATGTTCATGGACCTGGAGCTAACTTAGACAATTTTGAAACTCGAGATTTTCGGCA
GCTAATCCCCGGAACTTGTTTCTCAATTGAACCTGGCATTTATCTTCCTCACGAGTTTGGCGTTCGTTTAGAATACGATG
TGTATCTCTCTTTTGAAAAGAAAATACAAATCACTGGCGGAATTCAAGAAGAATTAGTTTGCCTAAATTTATGA

Upstream 100 bases:

>100_bases
TTTTAGCTGAGCAGCAAGAGGTTTCACCCATGATATGGAACACTTTTCAGGAGTGGTTAAGGATTAATCAATTATTATAA
AATTGTTTGGTTGGAATTTT

Downstream 100 bases:

>100_bases
TAACAAAGAAGAGTCAAAGAATGAGTTATGAGTTATAGGAGTAAAAAATGAAAGTACCTCTTTTTTCATTTAAAATGAGT
CGATTAGCTTTAATTATATT

Product: hypothetical protein

Products: NA

Alternate protein names: X-Pro aminopeptidase; Aminoacylproline aminopeptidase; Aminopeptidase P; APP [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MEFEKKLIEVQQQLKKEKINGWLLYDFRHSNSLAYIFLEIPASKMLSRRFFYWIPSSGEPIKIVPQIESHTLDHLPGIKW
IYKSWQELESQLFSLKLENHKVAMEYSPFNALPTLSKVDAGTIDFMRKNGVEVVSSANFIQRYTCVWNPQQLQSHLEAAE
ILSLIVDQTWNFIEKKLITSQAVDEYQVQQFMLKLMTEHNCVTADPPTCAINANSADPHYSPKKGQALSIRPGDFILLDL
WCKKNQPNSVYADITRVGVAAKNAQIKQKHIFNLVKETRDRATLFIKENYEAGLSIQGWQVDQLCRDVLNEKGYGEYFIH
RTGHNIGQDVHGPGANLDNFETRDFRQLIPGTCFSIEPGIYLPHEFGVRLEYDVYLSFEKKIQITGGIQEELVCLNL

Sequences:

>Translated_397_residues
MEFEKKLIEVQQQLKKEKINGWLLYDFRHSNSLAYIFLEIPASKMLSRRFFYWIPSSGEPIKIVPQIESHTLDHLPGIKW
IYKSWQELESQLFSLKLENHKVAMEYSPFNALPTLSKVDAGTIDFMRKNGVEVVSSANFIQRYTCVWNPQQLQSHLEAAE
ILSLIVDQTWNFIEKKLITSQAVDEYQVQQFMLKLMTEHNCVTADPPTCAINANSADPHYSPKKGQALSIRPGDFILLDL
WCKKNQPNSVYADITRVGVAAKNAQIKQKHIFNLVKETRDRATLFIKENYEAGLSIQGWQVDQLCRDVLNEKGYGEYFIH
RTGHNIGQDVHGPGANLDNFETRDFRQLIPGTCFSIEPGIYLPHEFGVRLEYDVYLSFEKKIQITGGIQEELVCLNL
>Mature_397_residues
MEFEKKLIEVQQQLKKEKINGWLLYDFRHSNSLAYIFLEIPASKMLSRRFFYWIPSSGEPIKIVPQIESHTLDHLPGIKW
IYKSWQELESQLFSLKLENHKVAMEYSPFNALPTLSKVDAGTIDFMRKNGVEVVSSANFIQRYTCVWNPQQLQSHLEAAE
ILSLIVDQTWNFIEKKLITSQAVDEYQVQQFMLKLMTEHNCVTADPPTCAINANSADPHYSPKKGQALSIRPGDFILLDL
WCKKNQPNSVYADITRVGVAAKNAQIKQKHIFNLVKETRDRATLFIKENYEAGLSIQGWQVDQLCRDVLNEKGYGEYFIH
RTGHNIGQDVHGPGANLDNFETRDFRQLIPGTCFSIEPGIYLPHEFGVRLEYDVYLSFEKKIQITGGIQEELVCLNL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=147, Percent_Identity=35.3741496598639, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.11.9 [H]

Molecular weight: Translated: 45735; Mature: 45735

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFEKKLIEVQQQLKKEKINGWLLYDFRHSNSLAYIFLEIPASKMLSRRFFYWIPSSGEP
CCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCHHHHHCCEEEEEECCCCCC
IKIVPQIESHTLDHLPGIKWIYKSWQELESQLFSLKLENHKVAMEYSPFNALPTLSKVDA
EEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCHHCCC
GTIDFMRKNGVEVVSSANFIQRYTCVWNPQQLQSHLEAAEILSLIVDQTWNFIEKKLITS
CHHHHHHCCCHHHHHCCHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVDEYQVQQFMLKLMTEHNCVTADPPTCAINANSADPHYSPKKGQALSIRPGDFILLDL
HHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEE
WCKKNQPNSVYADITRVGVAAKNAQIKQKHIFNLVKETRDRATLFIKENYEAGLSIQGWQ
EECCCCCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCC
VDQLCRDVLNEKGYGEYFIHRTGHNIGQDVHGPGANLDNFETRDFRQLIPGTCFSIEPGI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCE
YLPHEFGVRLEYDVYLSFEKKIQITGGIQEELVCLNL
ECCHHCCCEEEEEEEEEEEEEEEEECCCCCCEEEECC
>Mature Secondary Structure
MEFEKKLIEVQQQLKKEKINGWLLYDFRHSNSLAYIFLEIPASKMLSRRFFYWIPSSGEP
CCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEEEEEEECCHHHHHCCEEEEEECCCCCC
IKIVPQIESHTLDHLPGIKWIYKSWQELESQLFSLKLENHKVAMEYSPFNALPTLSKVDA
EEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCCCCCCCHHCCC
GTIDFMRKNGVEVVSSANFIQRYTCVWNPQQLQSHLEAAEILSLIVDQTWNFIEKKLITS
CHHHHHHCCCHHHHHCCHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QAVDEYQVQQFMLKLMTEHNCVTADPPTCAINANSADPHYSPKKGQALSIRPGDFILLDL
HHHHHHHHHHHHHHHHHCCCCEECCCCEEEEECCCCCCCCCCCCCCEEEECCCCEEEEEE
WCKKNQPNSVYADITRVGVAAKNAQIKQKHIFNLVKETRDRATLFIKENYEAGLSIQGWQ
EECCCCCCCHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCC
VDQLCRDVLNEKGYGEYFIHRTGHNIGQDVHGPGANLDNFETRDFRQLIPGTCFSIEPGI
HHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCCE
YLPHEFGVRLEYDVYLSFEKKIQITGGIQEELVCLNL
ECCHHCCCEEEEEEEEEEEEEEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8948633 [H]