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The map label for this gene is hslV

Identifier: 45657472

GI number: 45657472

Start: 1959527

End: 1960069

Strand: Direct

Name: hslV

Synonym: LIC11600

Alternate gene names: 45657472

Gene position: 1959527-1960069 (Clockwise)

Preceding gene: 45657471

Following gene: 45657473

Centisome position: 45.81

GC content: 40.7

Gene sequence:

>543_bases
ATGCCAGAAAATAAAATTCGTTCTACAACCATTCTCTGTGTACGAAAAAACGGAAAAGTAGCCATCGGAGGTGACGGTCA
GGTTTCTATGGGAAACACCGTTATGAAGAACACGGCTAAAAAAATTAGAAGACTTTATGACGGAAAAATTCTTTCCGGTT
TTGCCGGATCTGCTGCAGATGCATTTACACTTTTTGAACTTTTTGAAAAGAAGGTTCAAGAATTTGGAGGAAGTCTTTCT
AGAAGCGCTGTAGAACTTGCAAGAGAATGGAGAACGGATCGAATGCTTCGAAGACTAGAAGCGCTTCTCATCGTAGCCGA
TAAGGAAGAATCTTTTTTGATTTCTGGAACTGGAGATGTGATTTCTCCAGACGAAGGAGTGATCGCGATTGGTTCGGGTG
GAAATTACGCGTTAGCCGCTGCTCGTGCGCTTTACGATCATACCAATCTTTCTCCCAAAGAGATAGTAGAGTCTTCGATG
AAGATTGCGGCGGATATTTGTATTTATACAAACAATCATATAACCCTAGAAGAAATTCTTTAA

Upstream 100 bases:

>100_bases
GTACAAGAATTACTCGGACATTCTTCTCTTTCCACAACTCAAATTTATTTAAGTGTGAGTAAGGAAAAAATCAAAGAGGT
TTATAGAAAGGCCCATCCAC

Downstream 100 bases:

>100_bases
AATAAAAGTATGGCAAATCATCCAATAGACCAGGAACTTACATCACCGGCAGAAGAAGAGCTTACGCCTAGAGAAATCGT
AGCAAAATTAGACGAACATA

Product: ATP-dependent protease peptidase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MPENKIRSTTILCVRKNGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLS
RSAVELAREWRTDRMLRRLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGNYALAAARALYDHTNLSPKEIVESSM
KIAADICIYTNNHITLEEIL

Sequences:

>Translated_180_residues
MPENKIRSTTILCVRKNGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLS
RSAVELAREWRTDRMLRRLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGNYALAAARALYDHTNLSPKEIVESSM
KIAADICIYTNNHITLEEIL
>Mature_179_residues
PENKIRSTTILCVRKNGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAADAFTLFELFEKKVQEFGGSLSR
SAVELAREWRTDRMLRRLEALLIVADKEESFLISGTGDVISPDEGVIAIGSGGNYALAAARALYDHTNLSPKEIVESSMK
IAADICIYTNNHITLEEIL

Specific function: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery [H]

COG id: COG5405

COG function: function code O; ATP-dependent protease HslVU (ClpYQ), peptidase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family. HslV subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790367, Length=171, Percent_Identity=61.4035087719298, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022281
- InterPro:   IPR001353 [H]

Pfam domain/function: PF00227 Proteasome [H]

EC number: 3.4.25.-

Molecular weight: Translated: 19585; Mature: 19454

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPENKIRSTTILCVRKNGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAAD
CCCCCCCCEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEECCCCCHHH
AFTLFELFEKKVQEFGGSLSRSAVELAREWRTDRMLRRLEALLIVADKEESFLISGTGDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCC
ISPDEGVIAIGSGGNYALAAARALYDHTNLSPKEIVESSMKIAADICIYTNNHITLEEIL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCEEHHCCC
>Mature Secondary Structure 
PENKIRSTTILCVRKNGKVAIGGDGQVSMGNTVMKNTAKKIRRLYDGKILSGFAGSAAD
CCCCCCCEEEEEEECCCEEEECCCCCEECCHHHHHHHHHHHHHHHCCCEEECCCCCHHH
AFTLFELFEKKVQEFGGSLSRSAVELAREWRTDRMLRRLEALLIVADKEESFLISGTGDV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCC
ISPDEGVIAIGSGGNYALAAARALYDHTNLSPKEIVESSMKIAADICIYTNNHITLEEIL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEECCCEEHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA