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The map label for this gene is xerC

Identifier: 45657471

GI number: 45657471

Start: 1958542

End: 1959540

Strand: Direct

Name: xerC

Synonym: LIC11599

Alternate gene names: 45657471

Gene position: 1958542-1959540 (Clockwise)

Preceding gene: 45657470

Following gene: 45657472

Centisome position: 45.79

GC content: 34.13

Gene sequence:

>999_bases
TTGAATCATCAAGTTGTAAAGTGGTTCGGTTTTTTTGTAGAAATGATTTTATGGAGAATTTCATTGGGTGACTATCCTTT
CCAATTTCCAGAATTTTCTTCCGAATCTTTAAATGAAACGGCTAAGAAATTCATAAACTATTTAAAGATCGAAAAGAACT
ATTCACAAAACACAATCAACGCTTACAGTATTGATTTAAAATTTTTTTTCGAGTTTTGTGAAAAAGAACAACTAGATATT
TTTCAGATCGAACCAGTGGATATCCGATCTTACTTTGCGTATCTCGCAAAAAAACACGAGATAGATCGCAGGTCTCAAAG
TAGAAAGTTATCTTCTCTTAGAACCTTTTACAAGGTTCTTTTGAGAGAGGATCTAGTAAAATCCAATCCGGCTACTCAAC
TCAGTTTTCCTAAAGTTAGAAAAGAAGTTCCTAAAAATTTCAGGATAAACGAAACGGAAGAAATCCTGGAATTTGAGTCA
GAAAATGCTTCCGAAGTTTCGGAAATCAGAGATAGGGCGATGATCGAGGTTTTATATTCTTCCGGTCTTAGGGTATTTGA
ACTTGTAAATGCAAAACTAAATTCTCTTTCTAAGGACTTAACAGTTCTTAAAGTTCTTGGTAAAGGACGAAAGGAAAGAT
TTGTATATTTTGGTAAAGAGGCAGTAAGTTCGTTACAAAAATATTTGGAATATAGAAACGTTTCTTTTCCAGATGCAGAG
GAAATTTTTCTGAATCAAAGAGGAAAGAAACTGACGACTCGAGGGGTTCGATATATTTTGAATGAAAGAAGAAAAAAAAT
GGGTTGGGAAAAAACGATCACACCCCATAAATTTAGACATACTTTTGCGACCGATCTTTTAGACGCTGGAGCTGAAATTA
GAGCGGTACAAGAATTACTCGGACATTCTTCTCTTTCCACAACTCAAATTTATTTAAGTGTGAGTAAGGAAAAAATCAAA
GAGGTTTATAGAAAGGCCCATCCACATGCCAGAAAATAA

Upstream 100 bases:

>100_bases
ATAAAATGAATTTTTAATATAATGACCACAAAACGGCGATTTCATGCTGGAATTTGTTGTACGATCATTGTCTTAGGATT
TCTAAAAAATCTCTATTGTT

Downstream 100 bases:

>100_bases
AATTCGTTCTACAACCATTCTCTGTGTACGAAAAAACGGAAAAGTAGCCATCGGAGGTGACGGTCAGGTTTCTATGGGAA
ACACCGTTATGAAGAACACG

Product: putative integrase/recombinase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MNHQVVKWFGFFVEMILWRISLGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTINAYSIDLKFFFEFCEKEQLDI
FQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVLLREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFES
ENASEVSEIRDRAMIEVLYSSGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAE
EIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELLGHSSLSTTQIYLSVSKEKIK
EVYRKAHPHARK

Sequences:

>Translated_332_residues
MNHQVVKWFGFFVEMILWRISLGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTINAYSIDLKFFFEFCEKEQLDI
FQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVLLREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFES
ENASEVSEIRDRAMIEVLYSSGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAE
EIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELLGHSSLSTTQIYLSVSKEKIK
EVYRKAHPHARK
>Mature_332_residues
MNHQVVKWFGFFVEMILWRISLGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTINAYSIDLKFFFEFCEKEQLDI
FQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVLLREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFES
ENASEVSEIRDRAMIEVLYSSGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAE
EIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELLGHSSLSTTQIYLSVSKEKIK
EVYRKAHPHARK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=33.445945945946, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=35.9322033898305, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 39179; Mature: 39179

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHQVVKWFGFFVEMILWRISLGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTIN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
AYSIDLKFFFEFCEKEQLDIFQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVL
EEEHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFESENASEVSEIRDRAMIEVLYS
HHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECHHHHHHHHHHHHHCCCCCCCHH
EIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
GHSSLSTTQIYLSVSKEKIKEVYRKAHPHARK
CCCCCCCEEEEEEECHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNHQVVKWFGFFVEMILWRISLGDYPFQFPEFSSESLNETAKKFINYLKIEKNYSQNTIN
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
AYSIDLKFFFEFCEKEQLDIFQIEPVDIRSYFAYLAKKHEIDRRSQSRKLSSLRTFYKVL
EEEHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREDLVKSNPATQLSFPKVRKEVPKNFRINETEEILEFESENASEVSEIRDRAMIEVLYS
HHHHHHHCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SGLRVFELVNAKLNSLSKDLTVLKVLGKGRKERFVYFGKEAVSSLQKYLEYRNVSFPDAE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEECHHHHHHHHHHHHHCCCCCCCHH
EIFLNQRGKKLTTRGVRYILNERRKKMGWEKTITPHKFRHTFATDLLDAGAEIRAVQELL
HHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
GHSSLSTTQIYLSVSKEKIKEVYRKAHPHARK
CCCCCCCEEEEEEECHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA