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The map label for this gene is ptsK

Identifier: 45657419

GI number: 45657419

Start: 1908675

End: 1909640

Strand: Direct

Name: ptsK

Synonym: LIC11546

Alternate gene names: 45657419

Gene position: 1908675-1909640 (Clockwise)

Preceding gene: 45657418

Following gene: 45657420

Centisome position: 44.62

GC content: 39.13

Gene sequence:

>966_bases
ATGTCTATGCCTGGTATTAACGTTTCTAATCTTCTCAATGAACATGAAGAGTTAGGCTTACGTTTACTTGCGGGTCAAAA
AGGTCTTACCAATCGGATCAATATGTCGGAGATAAATCGTCCCGGACTTTCTCTTACTGGATTTTACGAAAGTTTTGCAC
ACGACAGAATTCAGATTTTTGGTAAGGGAGAATGGGCTTACATTACTTCCAGGACTCCGGAGGATTTGGAAAAAATAGCC
GCGGAGTTTTTCGGATTTCATCTCAATTGTATCATATTCACTCATGGCAATATGCCCCCTCCTATTTTTATGGAGAATTG
TGAGAAGTTAGGAATACCGCTGATGATCTCGGAAGTTTCCACTCACAAATTTATCACTTTGATTTCCGGTATTTTAGATC
GAAGTCTTGCGCCAAGAACGATGAGACACGGAGTTTTGATAGAGGTTTTTGGGATTGGAATTCTACTTTCTGGAAAAAGT
GGAGTAGGTAAAAGTGAAACCGCTCTCGAGCTGATAGAAAGGGGGCATCGCCTTGTTGCAGATGATATGGTGGAAATCAG
AAGACTTTCCGAAAGTTATTTAATTGGAACTTGTTCTGATCTACTTAGGCATCATATGGAAATCAGAGGATTAGGAATTC
TGAATATTAAAGATATATTTGGAATTGGATCTGTAAGAGATCACAAACTCATCGAACTTATTATTCATTTGGAAGAATGG
ACAGAAGGTAAAGATTTTGATAGAACGGGGCTTGAAAATCCCACGGAAGAACTTTTAGGAGTTCAAATCCCATTGATTCG
AGTTCCGGTGAGACCCGGAAGAAATATTCCGATTATTGTGGAAACCGCAGCGATGAATCAACGTCTTCGTAAATTGGGCA
AAAACGCAGCGCAAGAATTCAATCAAAAGTTAAGTCAGTATTTACAGCAGGGTAAAGTTGAAAGAAATCCTACTCAAAAT
CAATGA

Upstream 100 bases:

>100_bases
GAAATTGCAAGAAGAACCGTCGCTAAATATAGAAAGATTTTGAAAATCCTACCATCCAGCCAGAGAAAAAAAGTCAAGTC
TTTGGAGTCTAGATAAGTCT

Downstream 100 bases:

>100_bases
AAATGGAACTGGAATGCACGCAAGACCCGCGTCTGTATTTGTGAATTGTGCATCTAAATTTCCCTGTGAAATTACTGTCG
TTAAAGACGACGTAGTAGTA

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSMPGINVSNLLNEHEELGLRLLAGQKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIFGKGEWAYITSRTPEDLEKIA
AEFFGFHLNCIIFTHGNMPPPIFMENCEKLGIPLMISEVSTHKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKS
GVGKSETALELIERGHRLVADDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIHLEEW
TEGKDFDRTGLENPTEELLGVQIPLIRVPVRPGRNIPIIVETAAMNQRLRKLGKNAAQEFNQKLSQYLQQGKVERNPTQN
Q

Sequences:

>Translated_321_residues
MSMPGINVSNLLNEHEELGLRLLAGQKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIFGKGEWAYITSRTPEDLEKIA
AEFFGFHLNCIIFTHGNMPPPIFMENCEKLGIPLMISEVSTHKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKS
GVGKSETALELIERGHRLVADDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIHLEEW
TEGKDFDRTGLENPTEELLGVQIPLIRVPVRPGRNIPIIVETAAMNQRLRKLGKNAAQEFNQKLSQYLQQGKVERNPTQN
Q
>Mature_320_residues
SMPGINVSNLLNEHEELGLRLLAGQKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIFGKGEWAYITSRTPEDLEKIAA
EFFGFHLNCIIFTHGNMPPPIFMENCEKLGIPLMISEVSTHKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKSG
VGKSETALELIERGHRLVADDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIHLEEWT
EGKDFDRTGLENPTEELLGVQIPLIRVPVRPGRNIPIIVETAAMNQRLRKLGKNAAQEFNQKLSQYLQQGKVERNPTQNQ

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HPRK_LEPIC (Q72S40)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001505.1
- ProteinModelPortal:   Q72S40
- SMR:   Q72S40
- GeneID:   2771977
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11546
- HOGENOM:   HBG566466
- OMA:   IHGVLVD
- ProtClustDB:   PRK05428
- BioCyc:   LINT267671:LIC_11546-MONOMER
- HAMAP:   MF_01249
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126
- TIGRFAMs:   TIGR00679

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N

EC number: NA

Molecular weight: Translated: 36120; Mature: 35988

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: ACT_SITE 143-143 ACT_SITE 164-164 ACT_SITE 182-182 ACT_SITE 248-248

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPGINVSNLLNEHEELGLRLLAGQKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIF
CCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHCCCCCCEEHHHHHHHCCCEEEEE
GKGEWAYITSRTPEDLEKIAAEFFGFHLNCIIFTHGNMPPPIFMENCEKLGIPLMISEVS
ECCCEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHH
THKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKSGVGKSETALELIERGHRLVA
HHHHHHHHHHHHHCCCCCHHHHCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHH
DDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIHLEEW
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHH
TEGKDFDRTGLENPTEELLGVQIPLIRVPVRPGRNIPIIVETAAMNQRLRKLGKNAAQEF
CCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
NQKLSQYLQQGKVERNPTQNQ
HHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SMPGINVSNLLNEHEELGLRLLAGQKGLTNRINMSEINRPGLSLTGFYESFAHDRIQIF
CCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCHHHCCCCCCEEHHHHHHHCCCEEEEE
GKGEWAYITSRTPEDLEKIAAEFFGFHLNCIIFTHGNMPPPIFMENCEKLGIPLMISEVS
ECCCEEEEECCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHCCCCEEEEHHH
THKFITLISGILDRSLAPRTMRHGVLIEVFGIGILLSGKSGVGKSETALELIERGHRLVA
HHHHHHHHHHHHHCCCCCHHHHCCEEEEEEEEEEEEECCCCCCCHHHHHHHHHCCCHHHH
DDMVEIRRLSESYLIGTCSDLLRHHMEIRGLGILNIKDIFGIGSVRDHKLIELIIHLEEW
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHCCEEEEHHHHHCCCCCCHHHHHHHHHHHHHH
TEGKDFDRTGLENPTEELLGVQIPLIRVPVRPGRNIPIIVETAAMNQRLRKLGKNAAQEF
CCCCCCCCCCCCCCHHHHHCCCCCEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHH
NQKLSQYLQQGKVERNPTQNQ
HHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA