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The map label for this gene is flhB

Identifier: 45657253

GI number: 45657253

Start: 1690856

End: 1692805

Strand: Direct

Name: flhB

Synonym: LIC11375

Alternate gene names: 45657253

Gene position: 1690856-1692805 (Clockwise)

Preceding gene: 45657252

Following gene: 45657254

Centisome position: 39.53

GC content: 36.67

Gene sequence:

>1950_bases
GTGGCCGAAATGAAAAAGGCGATTTGGTCGAGAACAAAAAAACTGGTGGTTGTTTTCGTGCAAAATCCTAAAAGATTTTT
TATAAGAATTTTCTACAAGAACCTTTCTAGGGTTCCTTGGGTTTGTGAATCGGGTAAGGATTCTTTCGTAAAATCGGTGT
TAGACGTATTTTATCGTTTTATGCTTTTTGGGAAACGTTTCGGGAAGTTTATTTTTTGGAAACAGTACTATGATATAGTT
TCTGATTTTAGTAAAAAATGTGAGAGTTCCCACAATTTACACGAGATCAAAAATCTTATGGGAGTTCCCACAATTTACAC
GAGATCAAAAATCTTATGGGAGTTCCCACAATTTACACAAGATCGAAAATCTTGTAAGAGTTCCTACAATTTACAAAACG
TCGTAAAATCAGAGTCCAACAGTGATCACTTTTCTAATCGAAATACTGTTTCTTTACAAAACAGACAAGAAGGTCTTGTA
ATAAAAGATGTTGTACATCCTACATCTTTTATTTTCAGTTTCCTTCATCATTTTGATCGATGGGGACAGAAATCAACATC
TCATTCTCTATGGATGTTTCGAACAATTGAGAGATTTTTTTCTATTATAAAAAAACTTTTTTTTAAAAAAAAGTTTTCAA
AGTCTTTCATTGTCGGGATTTTTTTATTCTATAAAAAAATTGTCAAAAAATTTCTAGGTTATTCAGAACCAATTGATTCC
AAGTTAACAGAGTTTTTAAATTCTAATTTGTTTTGTTACTTTTTGCAATTTGGTTTTATAAACTTAACGATTGAGATCGT
TCGACGTATCTTTCGATTTAAAATTTTCCCACCTAATATATGTTTATCGACTGAAGCCGCCGATTTCAAAATAGATCTAC
AGTTATTTGCCGCCGAAGATGAGGGTAGAACAGAACCCGGATCGGAAAGAAGAAGAAGGGAAGAAAGAGAAAAAGGAAAC
GTTCCTAAGTCTCCTGAACTTCCAGCGGCGGTAGTGTTGCTTGCCGGAGTCATTTTAGTGTATCTCATGGGAGAATATTT
TTTCATGAGAACGTATTACATTTTACGCAAATACATTCACGGAGTAGGTCTTAGAACTGACATGAGTTCTGAGTCCGTGA
CCGAACTTTTAAAAAATGCTTCCACAGATTTATTTACTCTTCTTTGGCCTTTGCTCGGGATTACGTTAGTGGGTGCAATC
ATCGGAAATGTAGCACAGGTAGGTTTTATATTTACACCTCGTGCATTAAGTTTTAACTTTAGTAGAATTAGACCTAACTT
TAAGAAAGTGTTACCTACACGTCAGACACTTTTCAATTTGGGAAAGTCTCTTGCAAAAGTAGGATTAATCGCTTGGGTTT
CTTATATTATTATTAGTAAAGATTTTTTTCCGATTCTTCTTTCTGGGGAAATGGGACTAGAACAAGCGGTTGCGCTTGTG
ATGAACAGTTCCTTTAAGATATTTTTAATCGTTGGAATCATACTACTTGCGATCAGTATTGTAGACTATTTATATCAAAG
ATACGAATATGAAGAATCTTTAAAGATGACTCCTTCCGAAGCAAAAAGAGAGGCTAAGGAATCCGACGGGGACAGATCTC
TCCAAGCAAGGAGAAGACAACTCGCTCGGGATATGATGAATAAAAGGAAGATGTTAGCTAAGGTTCCAGAAGCGGACGTA
GTGATCACAAATCCTACCCATTTTGCGGTAGCCTTAGAATATAAACCTGGAATTCATAAGGCTCCGATTGTGATTGCAAA
AGGAGTGGACGATTTTGCTCTGCTGATCATTCGAATTGCAAGAGAAAACGGAGTGCCCACCGTGGAAGATCGTCTTCAAG
CAAGAGGGCTTTATGAGGAAGTGGAACTAGGCGCGGAAGTTCCTCAACAATTCTATCGCGCGATTGCAACCATTCTCTCT
CGTTTGGAATCCTTCCGGAGAGCCGTGTAA

Upstream 100 bases:

>100_bases
TTGGTCTGATCGTGATGATTTTTATCACTCCTTACCTGGTCTCTCAAATGGGAGCGGCTTTTGATTTATCCTTTGATAAG
GTAAATTTAATGTTACAAGA

Downstream 100 bases:

>100_bases
GAGGAAGTTATGGAAAAGAAATGGTGGAACCAGTCGGATGTAATTTTGGGAATTGGAGCGGTGGCGGTAGTGGCGATGCT
TGTCATTCCTCTTCCAGGAT

Product: flagellar biosynthesis protein FlhB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 649; Mature: 648

Protein sequence:

>649_residues
MAEMKKAIWSRTKKLVVVFVQNPKRFFIRIFYKNLSRVPWVCESGKDSFVKSVLDVFYRFMLFGKRFGKFIFWKQYYDIV
SDFSKKCESSHNLHEIKNLMGVPTIYTRSKILWEFPQFTQDRKSCKSSYNLQNVVKSESNSDHFSNRNTVSLQNRQEGLV
IKDVVHPTSFIFSFLHHFDRWGQKSTSHSLWMFRTIERFFSIIKKLFFKKKFSKSFIVGIFLFYKKIVKKFLGYSEPIDS
KLTEFLNSNLFCYFLQFGFINLTIEIVRRIFRFKIFPPNICLSTEAADFKIDLQLFAAEDEGRTEPGSERRRREEREKGN
VPKSPELPAAVVLLAGVILVYLMGEYFFMRTYYILRKYIHGVGLRTDMSSESVTELLKNASTDLFTLLWPLLGITLVGAI
IGNVAQVGFIFTPRALSFNFSRIRPNFKKVLPTRQTLFNLGKSLAKVGLIAWVSYIIISKDFFPILLSGEMGLEQAVALV
MNSSFKIFLIVGIILLAISIVDYLYQRYEYEESLKMTPSEAKREAKESDGDRSLQARRRQLARDMMNKRKMLAKVPEADV
VITNPTHFAVALEYKPGIHKAPIVIAKGVDDFALLIIRIARENGVPTVEDRLQARGLYEEVELGAEVPQQFYRAIATILS
RLESFRRAV

Sequences:

>Translated_649_residues
MAEMKKAIWSRTKKLVVVFVQNPKRFFIRIFYKNLSRVPWVCESGKDSFVKSVLDVFYRFMLFGKRFGKFIFWKQYYDIV
SDFSKKCESSHNLHEIKNLMGVPTIYTRSKILWEFPQFTQDRKSCKSSYNLQNVVKSESNSDHFSNRNTVSLQNRQEGLV
IKDVVHPTSFIFSFLHHFDRWGQKSTSHSLWMFRTIERFFSIIKKLFFKKKFSKSFIVGIFLFYKKIVKKFLGYSEPIDS
KLTEFLNSNLFCYFLQFGFINLTIEIVRRIFRFKIFPPNICLSTEAADFKIDLQLFAAEDEGRTEPGSERRRREEREKGN
VPKSPELPAAVVLLAGVILVYLMGEYFFMRTYYILRKYIHGVGLRTDMSSESVTELLKNASTDLFTLLWPLLGITLVGAI
IGNVAQVGFIFTPRALSFNFSRIRPNFKKVLPTRQTLFNLGKSLAKVGLIAWVSYIIISKDFFPILLSGEMGLEQAVALV
MNSSFKIFLIVGIILLAISIVDYLYQRYEYEESLKMTPSEAKREAKESDGDRSLQARRRQLARDMMNKRKMLAKVPEADV
VITNPTHFAVALEYKPGIHKAPIVIAKGVDDFALLIIRIARENGVPTVEDRLQARGLYEEVELGAEVPQQFYRAIATILS
RLESFRRAV
>Mature_648_residues
AEMKKAIWSRTKKLVVVFVQNPKRFFIRIFYKNLSRVPWVCESGKDSFVKSVLDVFYRFMLFGKRFGKFIFWKQYYDIVS
DFSKKCESSHNLHEIKNLMGVPTIYTRSKILWEFPQFTQDRKSCKSSYNLQNVVKSESNSDHFSNRNTVSLQNRQEGLVI
KDVVHPTSFIFSFLHHFDRWGQKSTSHSLWMFRTIERFFSIIKKLFFKKKFSKSFIVGIFLFYKKIVKKFLGYSEPIDSK
LTEFLNSNLFCYFLQFGFINLTIEIVRRIFRFKIFPPNICLSTEAADFKIDLQLFAAEDEGRTEPGSERRRREEREKGNV
PKSPELPAAVVLLAGVILVYLMGEYFFMRTYYILRKYIHGVGLRTDMSSESVTELLKNASTDLFTLLWPLLGITLVGAII
GNVAQVGFIFTPRALSFNFSRIRPNFKKVLPTRQTLFNLGKSLAKVGLIAWVSYIIISKDFFPILLSGEMGLEQAVALVM
NSSFKIFLIVGIILLAISIVDYLYQRYEYEESLKMTPSEAKREAKESDGDRSLQARRRQLARDMMNKRKMLAKVPEADVV
ITNPTHFAVALEYKPGIHKAPIVIAKGVDDFALLIIRIARENGVPTVEDRLQARGLYEEVELGAEVPQQFYRAIATILSR
LESFRRAV

Specific function: May be involved in the export of flagellum proteins [H]

COG id: COG1377

COG function: function code NU; Flagellar biosynthesis pathway, component FlhB

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III secretion exporter family [H]

Homologues:

Organism=Escherichia coli, GI1788188, Length=354, Percent_Identity=29.0960451977401, Blast_Score=129, Evalue=7e-31,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006136
- InterPro:   IPR006135 [H]

Pfam domain/function: PF01312 Bac_export_2 [H]

EC number: NA

Molecular weight: Translated: 75284; Mature: 75153

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEMKKAIWSRTKKLVVVFVQNPKRFFIRIFYKNLSRVPWVCESGKDSFVKSVLDVFYRF
CCHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
MLFGKRFGKFIFWKQYYDIVSDFSKKCESSHNLHEIKNLMGVPTIYTRSKILWEFPQFTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHH
DRKSCKSSYNLQNVVKSESNSDHFSNRNTVSLQNRQEGLVIKDVVHPTSFIFSFLHHFDR
HHHHHHHCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
WGQKSTSHSLWMFRTIERFFSIIKKLFFKKKFSKSFIVGIFLFYKKIVKKFLGYSEPIDS
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
KLTEFLNSNLFCYFLQFGFINLTIEIVRRIFRFKIFPPNICLSTEAADFKIDLQLFAAED
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCEEEEEEEEEECC
EGRTEPGSERRRREEREKGNVPKSPELPAAVVLLAGVILVYLMGEYFFMRTYYILRKYIH
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLRTDMSSESVTELLKNASTDLFTLLWPLLGITLVGAIIGNVAQVGFIFTPRALSFNF
HCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCH
SRIRPNFKKVLPTRQTLFNLGKSLAKVGLIAWVSYIIISKDFFPILLSGEMGLEQAVALV
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHH
MNSSFKIFLIVGIILLAISIVDYLYQRYEYEESLKMTPSEAKREAKESDGDRSLQARRRQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
LARDMMNKRKMLAKVPEADVVITNPTHFAVALEYKPGIHKAPIVIAKGVDDFALLIIRIA
HHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHH
RENGVPTVEDRLQARGLYEEVELGAEVPQQFYRAIATILSRLESFRRAV
HCCCCCCHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEMKKAIWSRTKKLVVVFVQNPKRFFIRIFYKNLSRVPWVCESGKDSFVKSVLDVFYRF
CHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
MLFGKRFGKFIFWKQYYDIVSDFSKKCESSHNLHEIKNLMGVPTIYTRSKILWEFPQFTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHCHHHHH
DRKSCKSSYNLQNVVKSESNSDHFSNRNTVSLQNRQEGLVIKDVVHPTSFIFSFLHHFDR
HHHHHHHCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
WGQKSTSHSLWMFRTIERFFSIIKKLFFKKKFSKSFIVGIFLFYKKIVKKFLGYSEPIDS
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
KLTEFLNSNLFCYFLQFGFINLTIEIVRRIFRFKIFPPNICLSTEAADFKIDLQLFAAED
HHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCCEEEEEEEEEECC
EGRTEPGSERRRREEREKGNVPKSPELPAAVVLLAGVILVYLMGEYFFMRTYYILRKYIH
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGLRTDMSSESVTELLKNASTDLFTLLWPLLGITLVGAIIGNVAQVGFIFTPRALSFNF
HCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHCCCH
SRIRPNFKKVLPTRQTLFNLGKSLAKVGLIAWVSYIIISKDFFPILLSGEMGLEQAVALV
HHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEECCCCCHHHHHHHH
MNSSFKIFLIVGIILLAISIVDYLYQRYEYEESLKMTPSEAKREAKESDGDRSLQARRRQ
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHH
LARDMMNKRKMLAKVPEADVVITNPTHFAVALEYKPGIHKAPIVIAKGVDDFALLIIRIA
HHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEEECCCCCCCCEEEECCCCHHHHHHHHHH
RENGVPTVEDRLQARGLYEEVELGAEVPQQFYRAIATILSRLESFRRAV
HCCCCCCHHHHHHHCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8299954; 9384377 [H]