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The map label for this gene is flhA

Identifier: 45657254

GI number: 45657254

Start: 1692815

End: 1694932

Strand: Direct

Name: flhA

Synonym: LIC11376

Alternate gene names: 45657254

Gene position: 1692815-1694932 (Clockwise)

Preceding gene: 45657253

Following gene: 45657255

Centisome position: 39.58

GC content: 40.6

Gene sequence:

>2118_bases
ATGGAAAAGAAATGGTGGAACCAGTCGGATGTAATTTTGGGAATTGGAGCGGTGGCGGTAGTGGCGATGCTTGTCATTCC
TCTTCCAGGATTTATATTAGATATTTTGATTATTGTCAGTTTGGCGATCGGACTTTTAGTTCTTTTGACTTCTCTTTCTG
TCAATGAACCTGCAGATTTTTCTATCTTTCCAAGTTTACTTTTGATTACTACCTTATATAGGCTTGCGTTGAACGTATCT
ACAACTAGACAGATACTTTCTAAAGGGCCCGCGATGAACAGTCACGTAATCGACGCTTTTGGATCGTTTATCATAGGAAG
CGAGTCTGGACTTTCCAAGTATGTGGTAGGTTTTATCATATTCATCATTTTGGTGCTCGTTCAGATTTTAGTGATTACTA
AAGGAGCGACTCGAATTTCGGAAGTTGCAGCTCGTTTTACTTTGGACGCCTTGCCTGGAAAACAAATGGCGATCGATATG
GAACTTTCTTCCGGAAATATCAACGAAGAAGAAGCTAAAAAAAGAAGAAAAAGAATCGAAGCCGAAGTAGATTTTTATGG
TTCTATGGATGGAGCGAGTAAGTTCGTACAAGGGGACGTTCGAGCCGGGCTGATTATCACCGCCATCAATCTGTTAGGTG
GAGTAATTATTGGATCTTCAATTCGGGGAGAATCTTTTACACAAGCCATCGAAACTTACGGGAAATTCACCATAGGAGAC
GGTCTCGTATCTCAGATTCCGGCACTTTTAACGACTGTAGCGACAGGTATCATCGTAACCCGCTCTGGGTCCGAGTCCGA
TTTGGCAACTCAGTTTAAAAGTCAACTATTTAGTAATTCAAAGGTTCTATATGTGGTTGCTGGAAGTTTAGGATTTGCTG
CATTTATTCCGGGGCTGCCATTTATTCCTTTGGTTCTGCTTTCTGCGGGAATTGCTTATTTAGGATATTCACTGGAACAA
ACTGTCAAAGAACAACTCGAGTCGATTGAGAAAAAAGAAAAAGAATCTGGCCAGGATCGTAAACCAAAAGATTTTTACGA
AGAACTGAGAACCGATCCGATTGAAATTGAAGTCGGTTATCATCTTATACCCTTAGTCGATGTTTCTCAAGGCGGGGCGC
TTTTAGATCAGATCAGTAATCTTAGAAAGAAGTTTGCGCAGGATAACGGCGTAGTGATTCCTCCCGTGAGAATATTAGAT
AATCTTGATTTAAATCCGGATACGTATTCGATTAAAATTAACGGAACCGAAGTAGGGGCTTCCACGGTAAAACCGGATAA
ATTGATGGCACTCAATACTAGTCCTGGAAGCGCGGAATCTATTGCCGGAGAGGATTTTTTAGAACCTTCTTTTGGCCAAA
GAGCAAAATGGATTTCTGCCGAAGACAAATCTGACGCGGAAGCAAAAGGTTATACAGTAGTAGATGCGTCCACGGTAGTA
GTGACACATTTGAAAGAACTTCTTGCGACGCACGCGTCCACTTTACTCGGAAGGGAAGAAGTCAAAAAACTTCTAGATCA
TTATAAAACAAGTTATCCGACTTTGATTGGAGAATTGGACGCGGATAAACCAGGTAACTTAGGAATCATTCAACAAGTAT
TACAAAATCTTTTAAGAGAAGGACTTGGCATTAGAAACTTGGTTCCAATTTTAGAATCGATTGCGAACAATTTGTCTAAA
TATCAAAATCCATATATACTCACAGAACTTGTACGTCAGTCCATTTCAAGAACCGTAGTTCGGGATTATCTATCCATGGA
TGGAAAGTTAAGGGTGATCACTCTCGAAAGTAGAATTTTGGATCGACTCAATAAATCCATTACTCAGGACAGAATCGAAA
ACAGAGACGTTCTGTCTCTTGCGCCAGATTTTTACAGAAGGTTGATTGATAGTGTGGCTGAACTTTATAGAAATTTTAGG
ACCGAAGGAAAGTTTCCTATTTTTGTAGTAAATCGAGAGGTACGTTTGCCTTTTTCGTATATGCTTGCAAAGGAATTTCC
TCCTCGCAATTTCGGAGTTCTTGCTTACGAGGAGATTCATTCTTCCGTAGATTCTGTAATTGAAGCTGAGCTCAAACTTC
CCCAGGCGCAGACTGCCGGAATTTCGGAAGAAACATGA

Upstream 100 bases:

>100_bases
AGTGGAACTAGGCGCGGAAGTTCCTCAACAATTCTATCGCGCGATTGCAACCATTCTCTCTCGTTTGGAATCCTTCCGGA
GAGCCGTGTAAGAGGAAGTT

Downstream 100 bases:

>100_bases
AATACTTAGAATATTCTAATTTTATAAAGTGGAATAATTAGAGGAGTTGAATATGGAGTTTGCTAAAATTCGGGGCAAAA
GTTATCAAGATTGTTTGATG

Product: flagellar biosynthesis transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 705; Mature: 705

Protein sequence:

>705_residues
MEKKWWNQSDVILGIGAVAVVAMLVIPLPGFILDILIIVSLAIGLLVLLTSLSVNEPADFSIFPSLLLITTLYRLALNVS
TTRQILSKGPAMNSHVIDAFGSFIIGSESGLSKYVVGFIIFIILVLVQILVITKGATRISEVAARFTLDALPGKQMAIDM
ELSSGNINEEEAKKRRKRIEAEVDFYGSMDGASKFVQGDVRAGLIITAINLLGGVIIGSSIRGESFTQAIETYGKFTIGD
GLVSQIPALLTTVATGIIVTRSGSESDLATQFKSQLFSNSKVLYVVAGSLGFAAFIPGLPFIPLVLLSAGIAYLGYSLEQ
TVKEQLESIEKKEKESGQDRKPKDFYEELRTDPIEIEVGYHLIPLVDVSQGGALLDQISNLRKKFAQDNGVVIPPVRILD
NLDLNPDTYSIKINGTEVGASTVKPDKLMALNTSPGSAESIAGEDFLEPSFGQRAKWISAEDKSDAEAKGYTVVDASTVV
VTHLKELLATHASTLLGREEVKKLLDHYKTSYPTLIGELDADKPGNLGIIQQVLQNLLREGLGIRNLVPILESIANNLSK
YQNPYILTELVRQSISRTVVRDYLSMDGKLRVITLESRILDRLNKSITQDRIENRDVLSLAPDFYRRLIDSVAELYRNFR
TEGKFPIFVVNREVRLPFSYMLAKEFPPRNFGVLAYEEIHSSVDSVIEAELKLPQAQTAGISEET

Sequences:

>Translated_705_residues
MEKKWWNQSDVILGIGAVAVVAMLVIPLPGFILDILIIVSLAIGLLVLLTSLSVNEPADFSIFPSLLLITTLYRLALNVS
TTRQILSKGPAMNSHVIDAFGSFIIGSESGLSKYVVGFIIFIILVLVQILVITKGATRISEVAARFTLDALPGKQMAIDM
ELSSGNINEEEAKKRRKRIEAEVDFYGSMDGASKFVQGDVRAGLIITAINLLGGVIIGSSIRGESFTQAIETYGKFTIGD
GLVSQIPALLTTVATGIIVTRSGSESDLATQFKSQLFSNSKVLYVVAGSLGFAAFIPGLPFIPLVLLSAGIAYLGYSLEQ
TVKEQLESIEKKEKESGQDRKPKDFYEELRTDPIEIEVGYHLIPLVDVSQGGALLDQISNLRKKFAQDNGVVIPPVRILD
NLDLNPDTYSIKINGTEVGASTVKPDKLMALNTSPGSAESIAGEDFLEPSFGQRAKWISAEDKSDAEAKGYTVVDASTVV
VTHLKELLATHASTLLGREEVKKLLDHYKTSYPTLIGELDADKPGNLGIIQQVLQNLLREGLGIRNLVPILESIANNLSK
YQNPYILTELVRQSISRTVVRDYLSMDGKLRVITLESRILDRLNKSITQDRIENRDVLSLAPDFYRRLIDSVAELYRNFR
TEGKFPIFVVNREVRLPFSYMLAKEFPPRNFGVLAYEEIHSSVDSVIEAELKLPQAQTAGISEET
>Mature_705_residues
MEKKWWNQSDVILGIGAVAVVAMLVIPLPGFILDILIIVSLAIGLLVLLTSLSVNEPADFSIFPSLLLITTLYRLALNVS
TTRQILSKGPAMNSHVIDAFGSFIIGSESGLSKYVVGFIIFIILVLVQILVITKGATRISEVAARFTLDALPGKQMAIDM
ELSSGNINEEEAKKRRKRIEAEVDFYGSMDGASKFVQGDVRAGLIITAINLLGGVIIGSSIRGESFTQAIETYGKFTIGD
GLVSQIPALLTTVATGIIVTRSGSESDLATQFKSQLFSNSKVLYVVAGSLGFAAFIPGLPFIPLVLLSAGIAYLGYSLEQ
TVKEQLESIEKKEKESGQDRKPKDFYEELRTDPIEIEVGYHLIPLVDVSQGGALLDQISNLRKKFAQDNGVVIPPVRILD
NLDLNPDTYSIKINGTEVGASTVKPDKLMALNTSPGSAESIAGEDFLEPSFGQRAKWISAEDKSDAEAKGYTVVDASTVV
VTHLKELLATHASTLLGREEVKKLLDHYKTSYPTLIGELDADKPGNLGIIQQVLQNLLREGLGIRNLVPILESIANNLSK
YQNPYILTELVRQSISRTVVRDYLSMDGKLRVITLESRILDRLNKSITQDRIENRDVLSLAPDFYRRLIDSVAELYRNFR
TEGKFPIFVVNREVRLPFSYMLAKEFPPRNFGVLAYEEIHSSVDSVIEAELKLPQAQTAGISEET

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=657, Percent_Identity=40.6392694063927, Blast_Score=458, Evalue=1e-130,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 77298; Mature: 77298

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKWWNQSDVILGIGAVAVVAMLVIPLPGFILDILIIVSLAIGLLVLLTSLSVNEPADF
CCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SIFPSLLLITTLYRLALNVSTTRQILSKGPAMNSHVIDAFGSFIIGSESGLSKYVVGFII
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHH
FIILVLVQILVITKGATRISEVAARFTLDALPGKQMAIDMELSSGNINEEEAKKRRKRIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCC
AEVDFYGSMDGASKFVQGDVRAGLIITAINLLGGVIIGSSIRGESFTQAIETYGKFTIGD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECC
GLVSQIPALLTTVATGIIVTRSGSESDLATQFKSQLFSNSKVLYVVAGSLGFAAFIPGLP
HHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCH
FIPLVLLSAGIAYLGYSLEQTVKEQLESIEKKEKESGQDRKPKDFYEELRTDPIEIEVGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECC
HLIPLVDVSQGGALLDQISNLRKKFAQDNGVVIPPVRILDNLDLNPDTYSIKINGTEVGA
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCEEEEEEECCCCCC
STVKPDKLMALNTSPGSAESIAGEDFLEPSFGQRAKWISAEDKSDAEAKGYTVVDASTVV
CCCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
VTHLKELLATHASTLLGREEVKKLLDHYKTSYPTLIGELDADKPGNLGIIQQVLQNLLRE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GLGIRNLVPILESIANNLSKYQNPYILTELVRQSISRTVVRDYLSMDGKLRVITLESRIL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
DRLNKSITQDRIENRDVLSLAPDFYRRLIDSVAELYRNFRTEGKFPIFVVNREVRLPFSY
HHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
MLAKEFPPRNFGVLAYEEIHSSVDSVIEAELKLPQAQTAGISEET
HHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MEKKWWNQSDVILGIGAVAVVAMLVIPLPGFILDILIIVSLAIGLLVLLTSLSVNEPADF
CCCCCCCCCCEEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SIFPSLLLITTLYRLALNVSTTRQILSKGPAMNSHVIDAFGSFIIGSESGLSKYVVGFII
HHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHH
FIILVLVQILVITKGATRISEVAARFTLDALPGKQMAIDMELSSGNINEEEAKKRRKRIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHCC
AEVDFYGSMDGASKFVQGDVRAGLIITAINLLGGVIIGSSIRGESFTQAIETYGKFTIGD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEECC
GLVSQIPALLTTVATGIIVTRSGSESDLATQFKSQLFSNSKVLYVVAGSLGFAAFIPGLP
HHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHCCCH
FIPLVLLSAGIAYLGYSLEQTVKEQLESIEKKEKESGQDRKPKDFYEELRTDPIEIEVGY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCEEEEECC
HLIPLVDVSQGGALLDQISNLRKKFAQDNGVVIPPVRILDNLDLNPDTYSIKINGTEVGA
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEECCHHHHCCCCCCCCEEEEEEECCCCCC
STVKPDKLMALNTSPGSAESIAGEDFLEPSFGQRAKWISAEDKSDAEAKGYTVVDASTVV
CCCCCCCEEEEECCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHH
VTHLKELLATHASTLLGREEVKKLLDHYKTSYPTLIGELDADKPGNLGIIQQVLQNLLRE
HHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GLGIRNLVPILESIANNLSKYQNPYILTELVRQSISRTVVRDYLSMDGKLRVITLESRIL
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHH
DRLNKSITQDRIENRDVLSLAPDFYRRLIDSVAELYRNFRTEGKFPIFVVNREVRLPFSY
HHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHH
MLAKEFPPRNFGVLAYEEIHSSVDSVIEAELKLPQAQTAGISEET
HHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]