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The map label for this gene is mreB

Identifier: 45657141

GI number: 45657141

Start: 1554326

End: 1555348

Strand: Direct

Name: mreB

Synonym: LIC11258

Alternate gene names: 45657141

Gene position: 1554326-1555348 (Clockwise)

Preceding gene: 45657136

Following gene: 45657142

Centisome position: 36.34

GC content: 43.79

Gene sequence:

>1023_bases
ATGATCTTTGATAATCTCTATGCCCTGTTTTCTAACGATATGGGAATCGATCTAGGAACGGCAAATACACTGGTGCATGT
TAAAGGACAAGGGATCGTTTTATCCGAACCCTCCGTTGTTGCGGTTCACGCTGCCACCGGTAAAGTCCTCGCTGTAGGGC
AGGAAGCAAAGCGGATGTTGGGACGTACTCCAGGAGAAATCGTCGCTATTCGTCCAATGAAAGACGGTGTGATTGCAGAT
TTTGAAACCGTCGAAAAAATGATTCGTTATTTTATCGCAAAGGTGCATAACCGAACTACATTCGTAAAACCTAGAATTGT
GATCGGAGTTCCGTCCGGAATTACAGAGGTAGAAAGACGTGCTGTTCGCGAGTCTGCAGAACAAGCAGGTGCGAGAGAAA
TTTTTTTGATCGAAGAAGCTCTTGCTGCTGCGATTGGTGCTAATATACCAATCAACGAACCTGCAGGAAATATGATCGTA
GACATAGGCGGTGGCACGACCGAAATCGCAGTCATTTCGTTAGGTGGAATGGTAATTGCGGAATCCATTCGAACTGGAGG
AGATGAGTTCGACGAAGCAATCATCAAATATCTCCGAAACCAATACAATTTAGTGGTAGGAGAAAGAACCGCAGAAGATA
TTAAACTCACCATAGGAAACGCATTTCCGGAAAAAAAAGCGGAAACGATGGAAGTTCGTGGGCGGGACGCAATTTCAGGA
CTTCCTAGAACTTTGGAACTGGAATCGAACGAAATTCGTAAAGCACTCAAAGAACCTACAGACGAAATTTTAGATGGAAT
CAAAAGGGTTTTAGAAAGAACACCTCCTGAGCTTGCATCGGATATAGTAGAAAGAGGAATTGTTCTAACCGGTGGCGGAT
GTCTCTTAAGAGGATTAGAAATGTATCTTTCTAAAGAAACTGGAGTTCCTGTCTTTCGTGCGGAAAATCCTCTTACCTGT
GTGGTACTCGGAACCGGAAAATATCTGGACGAGTTGAAGTATATCAAACCCGGTATACGTTAA

Upstream 100 bases:

>100_bases
GAAATTATTGAAACCTGTCCGACGAAGAAAATTCTGAAGAATTTTCAACTCTGAGCAGATAATAAAGACAAAAAACCTTC
GCGGTTGAAAGGTACCTGAA

Downstream 100 bases:

>100_bases
GAAATCGGTTGAAATTCGCTAACGTTTCGAACGACTTTTGTTCGGAACGGATTCGAGAGAAAAGGAAGAATCGATGTTAT
GGTTTCAACTCAGTCGAAGT

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: Protein mbl [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MIFDNLYALFSNDMGIDLGTANTLVHVKGQGIVLSEPSVVAVHAATGKVLAVGQEAKRMLGRTPGEIVAIRPMKDGVIAD
FETVEKMIRYFIAKVHNRTTFVKPRIVIGVPSGITEVERRAVRESAEQAGAREIFLIEEALAAAIGANIPINEPAGNMIV
DIGGGTTEIAVISLGGMVIAESIRTGGDEFDEAIIKYLRNQYNLVVGERTAEDIKLTIGNAFPEKKAETMEVRGRDAISG
LPRTLELESNEIRKALKEPTDEILDGIKRVLERTPPELASDIVERGIVLTGGGCLLRGLEMYLSKETGVPVFRAENPLTC
VVLGTGKYLDELKYIKPGIR

Sequences:

>Translated_340_residues
MIFDNLYALFSNDMGIDLGTANTLVHVKGQGIVLSEPSVVAVHAATGKVLAVGQEAKRMLGRTPGEIVAIRPMKDGVIAD
FETVEKMIRYFIAKVHNRTTFVKPRIVIGVPSGITEVERRAVRESAEQAGAREIFLIEEALAAAIGANIPINEPAGNMIV
DIGGGTTEIAVISLGGMVIAESIRTGGDEFDEAIIKYLRNQYNLVVGERTAEDIKLTIGNAFPEKKAETMEVRGRDAISG
LPRTLELESNEIRKALKEPTDEILDGIKRVLERTPPELASDIVERGIVLTGGGCLLRGLEMYLSKETGVPVFRAENPLTC
VVLGTGKYLDELKYIKPGIR
>Mature_340_residues
MIFDNLYALFSNDMGIDLGTANTLVHVKGQGIVLSEPSVVAVHAATGKVLAVGQEAKRMLGRTPGEIVAIRPMKDGVIAD
FETVEKMIRYFIAKVHNRTTFVKPRIVIGVPSGITEVERRAVRESAEQAGAREIFLIEEALAAAIGANIPINEPAGNMIV
DIGGGTTEIAVISLGGMVIAESIRTGGDEFDEAIIKYLRNQYNLVVGERTAEDIKLTIGNAFPEKKAETMEVRGRDAISG
LPRTLELESNEIRKALKEPTDEILDGIKRVLERTPPELASDIVERGIVLTGGGCLLRGLEMYLSKETGVPVFRAENPLTC
VVLGTGKYLDELKYIKPGIR

Specific function: Involved In Formation Of The Rod Shape Of The Cell. May Act As A Negative Regulator Of Ftsi. [C]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=335, Percent_Identity=58.5074626865672, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36836; Mature: 36836

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFDNLYALFSNDMGIDLGTANTLVHVKGQGIVLSEPSVVAVHAATGKVLAVGQEAKRML
CCCHHHHHHHCCCCCCEECCCCEEEEEECCEEEEECCCEEEEEECCCCEEEECHHHHHHH
GRTPGEIVAIRPMKDGVIADFETVEKMIRYFIAKVHNRTTFVKPRIVIGVPSGITEVERR
CCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHHHHHH
AVRESAEQAGAREIFLIEEALAAAIGANIPINEPAGNMIVDIGGGTTEIAVISLGGMVIA
HHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEEECCHHHH
ESIRTGGDEFDEAIIKYLRNQYNLVVGERTAEDIKLTIGNAFPEKKAETMEVRGRDAISG
HHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHCCCCHHHCC
LPRTLELESNEIRKALKEPTDEILDGIKRVLERTPPELASDIVERGIVLTGGGCLLRGLE
CCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHH
MYLSKETGVPVFRAENPLTCVVLGTGKYLDELKYIKPGIR
HHHHHCCCCCEEECCCCEEEEEEECCHHHHHHHHHCCCCC
>Mature Secondary Structure
MIFDNLYALFSNDMGIDLGTANTLVHVKGQGIVLSEPSVVAVHAATGKVLAVGQEAKRML
CCCHHHHHHHCCCCCCEECCCCEEEEEECCEEEEECCCEEEEEECCCCEEEECHHHHHHH
GRTPGEIVAIRPMKDGVIADFETVEKMIRYFIAKVHNRTTFVKPRIVIGVPSGITEVERR
CCCCCCEEEEEECCCCCEECHHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHHHHHH
AVRESAEQAGAREIFLIEEALAAAIGANIPINEPAGNMIVDIGGGTTEIAVISLGGMVIA
HHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCCCCCCCEEEECCCCCEEEEEEEECCHHHH
ESIRTGGDEFDEAIIKYLRNQYNLVVGERTAEDIKLTIGNAFPEKKAETMEVRGRDAISG
HHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCHHHHCCCCHHHCC
LPRTLELESNEIRKALKEPTDEILDGIKRVLERTPPELASDIVERGIVLTGGGCLLRGLE
CCCEEEECHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHHHHH
MYLSKETGVPVFRAENPLTCVVLGTGKYLDELKYIKPGIR
HHHHHCCCCCEEECCCCEEEEEEECCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1452027; 10217496 [H]