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The map label for this gene is murI

Identifier: 45656923

GI number: 45656923

Start: 1278471

End: 1279241

Strand: Direct

Name: murI

Synonym: LIC11039

Alternate gene names: 45656923

Gene position: 1278471-1279241 (Clockwise)

Preceding gene: 45656922

Following gene: 45656924

Centisome position: 29.89

GC content: 37.22

Gene sequence:

>771_bases
TTGAAAGAGCCGCTCAAGATCGGTCTAATGGATTCTGGAATGGGCGGTTTGTCCGTCCTGAAAGAACTTTTAAAATACGA
TTCGGAATTAGAAATTGTATATTACGGAGATCTAAAGAACAGTCCTTACGGAGAAAAGGACGCCTCTGAAGTTTTAGAAC
TCGTCAGAAGCGTTTGTAATTTTTTACAAAAGGAAAACGTAAGTGCGATTTTGCTCGCTTGTAATACTGCAACTTCCGCA
GCCGCACAAACTCTTAGAAAGGAATTTTCGATTCCTATTTTTGGAATGGAACCTGCAATCAAACCTGCAATTTTACAAAA
CCCAGGAAAGAAGGTGGCACTACTTGCCACTCCGGTTACACAAAGAGAAGAAAAATTACAGAGGTTAAAATCCGAACTAA
AGGCGGAGGAGTTGGTGCTTTCTATTTCTTGTCCCGGCTTGGCTGGACTTGTGGATCAGGGGGATTTTGACAAAGCCGAA
AAATATCTCCGACCTATTTTAGCAAATCTGCAAGAGCAGGATGTGGAGAATTTAGTATTAGGTTGTACACATTATGTTTT
TCTAAAACAGATTATTCTAAAAAACTTTCCTAATGTAAAAATTTATGACGGAAATTCAGGGACTATCAAACATTTATTAA
ATTCTTTGCAAGTTCCAAGAGTTATTTTAAATGGAAGTCAAAACAATCGGTCTATCTATAAATTGATTTTGAATAGCGAG
AAAGAGTTTCATTTTAGGCTGGCTTCCAAGCTTTTATCTTTGAAAGAATAA

Upstream 100 bases:

>100_bases
AGGAAAAATTCAATTGGATTTACAAAACGCTTCGGGATAAGATTGGCGAGTATATCGCTTCCGCCTAACGTATAATTGAA
ATCAAAATGGGGACTCGAAT

Downstream 100 bases:

>100_bases
AGTTATTGAAAGTTCAGATTAACAAAACTATCGTTCCCATAAAATAGAAATAGACGTAGAATGAATTTTTCAAAACAATT
CTAATAAAAAAAATCGCTCT

Product: glutamate racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCNFLQKENVSAILLACNTATSA
AAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVTQREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAE
KYLRPILANLQEQDVENLVLGCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSE
KEFHFRLASKLLSLKE

Sequences:

>Translated_256_residues
MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCNFLQKENVSAILLACNTATSA
AAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVTQREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAE
KYLRPILANLQEQDVENLVLGCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSE
KEFHFRLASKLLSLKE
>Mature_256_residues
MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCNFLQKENVSAILLACNTATSA
AAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVTQREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAE
KYLRPILANLQEQDVENLVLGCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSE
KEFHFRLASKLLSLKE

Specific function: Provides the (R)-glutamate required for cell wall biosynthesis

COG id: COG0796

COG function: function code M; Glutamate racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate/glutamate racemases family

Homologues:

Organism=Escherichia coli, GI87082355, Length=191, Percent_Identity=32.9842931937173, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURI_LEPIC (Q72TI2)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_001009.1
- ProteinModelPortal:   Q72TI2
- SMR:   Q72TI2
- GeneID:   2769539
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC11039
- NMPDR:   fig|267671.1.peg.1009
- HOGENOM:   HBG645102
- OMA:   ARTNAMI
- ProtClustDB:   CLSK574702
- BioCyc:   LINT267671:LIC_11039-MONOMER
- HAMAP:   MF_00258
- InterPro:   IPR015942
- InterPro:   IPR001920
- InterPro:   IPR004391
- Gene3D:   G3DSA:3.40.50.1860
- TIGRFAMs:   TIGR00067

Pfam domain/function: PF01177 Asp_Glu_race; SSF53681 Asp/Glu_race

EC number: =5.1.1.3

Molecular weight: Translated: 28504; Mature: 28504

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS00923 ASP_GLU_RACEMASE_1; PS00924 ASP_GLU_RACEMASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCN
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
FLQKENVSAILLACNTATSAAAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVT
HHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCCCCEEEEEECCCH
QREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAEKYLRPILANLQEQDVENLVL
HHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSE
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCC
KEFHFRLASKLLSLKE
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEPLKIGLMDSGMGGLSVLKELLKYDSELEIVYYGDLKNSPYGEKDASEVLELVRSVCN
CCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
FLQKENVSAILLACNTATSAAAQTLRKEFSIPIFGMEPAIKPAILQNPGKKVALLATPVT
HHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCEECCCCCCCCHHHCCCCCEEEEEECCCH
QREEKLQRLKSELKAEELVLSISCPGLAGLVDQGDFDKAEKYLRPILANLQEQDVENLVL
HHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GCTHYVFLKQIILKNFPNVKIYDGNSGTIKHLLNSLQVPRVILNGSQNNRSIYKLILNSE
HHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHCCCCEEECCCCCCCHHHHHHHCCC
KEFHFRLASKLLSLKE
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA