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The map label for this gene is yfbQ [C]

Identifier: 45656922

GI number: 45656922

Start: 1277134

End: 1278438

Strand: Direct

Name: yfbQ [C]

Synonym: LIC11038

Alternate gene names: 45656922

Gene position: 1277134-1278438 (Clockwise)

Preceding gene: 45656921

Following gene: 45656923

Centisome position: 29.86

GC content: 40.84

Gene sequence:

>1305_bases
ATGAGAAGAAACATCGTTCACAGCGGAGCGGACGCCCTAATTTATGAAATCAGACAGATCGTAGCCGTCGCAAAAAAGTT
AGAGGCACTGGGACTTCAGATTACTTACGAAAACATAGGAGATCCTATCTTAAAAGGAGAATCGATTCCAGATTGGATGA
AAGAAATAGTTTCCAATTTGATCTTAAAAGATAAGTCCTGGGCTTATACGGCCACACAAGGATATGAACCAACTCGTAAG
TTCTTAGCAGAAAAAGTGAACGAAAGGGGAGGCGCTCAGATCTCAGCGGACGATCTTTTATTTTTTAACGGACTGGGAGA
CGCGGTCGCAAAAATTTTCGGTTTTATGAGAAGGGAAGCTAGAGTATTAGGACCAAGTCCAGCGTATTCTACGATTTCTT
CTGCGGAAGCGGCGCATAGCGGCTATGAACACCTAACGTATAACTTACTTCCGGAACACAATTGGATGCCGGATCTAGAA
GATATGGAAAACAAGGTGAAATACAATGATTCTATAGCTGGAATATTACTGATTAACCCAGATAATCCCACCGGTGCAGT
ATATGATAAAAACTTAATGAAGAAGATAGTGGCGATCTGCGAAAAATACGATCTGATGTTAATTTGCGACGAAACTTATG
CACACGTAAATTATTCCGATCACGGTCCGCTTCATCTTTCGGAAGTAATCGGGGATAAGGTTCCCGGAATGGCGCTTAGA
TCTATTTCTAAAGAATTTCCCTGGCCTGGAGGACGTTGTGGATGGTTGGAAATATTTAACAAAGAGAAAGATCCGGTTTT
TAGTCGTTACGTAAAATCGTTGTTAGACGCAAAGATGCTCGAAGTATGTTCTACTACTTTGCCACAGATGGCAATTCCGG
AAGTGTATTCTCATCCTGATTTTATTCCTCATCTAAAAAGAAGAAACGAAAAATTCAAAAAACGCGCACACGTAGCAACG
GAATATTTTGCAGAATTAAGAGGGGTTAAGGTAGTAGAACCAAAAGGGGCTTTTTATCTTACGGTCGCTTTTGACGACGA
CGTTTTAAATTCTTCCATGAAATTGGAAATTGAAAATAAAAAGGCGGACGAATTTATCCAACCTCTATTGGCTTCCGCGG
CAAACGACAGAAGGTTTGTATATTATTTGCTTGCGTCCACCGGTATTTGTGTGGTTCCTTTATCAGCGTTTTGTACTTTA
AAAGACGGATTTCGCGTAACGTTGTTAGAGGAAGACGAGGAAAAATTCAATTGGATTTACAAAACGCTTCGGGATAAGAT
TGGCGAGTATATCGCTTCCGCCTAA

Upstream 100 bases:

>100_bases
CTACGTATCTACCGGGAAAAATCGATGCAGGAACTTTCGATAAAGTTGATTCAGAAATAGAAATGGATAAGAATTTTTTA
GAGGAAAAAGAGAAAACCGG

Downstream 100 bases:

>100_bases
CGTATAATTGAAATCAAAATGGGGACTCGAATTTGAAAGAGCCGCTCAAGATCGGTCTAATGGATTCTGGAATGGGCGGT
TTGTCCGTCCTGAAAGAACT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MRRNIVHSGADALIYEIRQIVAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSNLILKDKSWAYTATQGYEPTRK
FLAEKVNERGGAQISADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVKYNDSIAGILLINPDNPTGAVYDKNLMKKIVAICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYVKSLLDAKMLEVCSTTLPQMAIPEVYSHPDFIPHLKRRNEKFKKRAHVAT
EYFAELRGVKVVEPKGAFYLTVAFDDDVLNSSMKLEIENKKADEFIQPLLASAANDRRFVYYLLASTGICVVPLSAFCTL
KDGFRVTLLEEDEEKFNWIYKTLRDKIGEYIASA

Sequences:

>Translated_434_residues
MRRNIVHSGADALIYEIRQIVAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSNLILKDKSWAYTATQGYEPTRK
FLAEKVNERGGAQISADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVKYNDSIAGILLINPDNPTGAVYDKNLMKKIVAICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYVKSLLDAKMLEVCSTTLPQMAIPEVYSHPDFIPHLKRRNEKFKKRAHVAT
EYFAELRGVKVVEPKGAFYLTVAFDDDVLNSSMKLEIENKKADEFIQPLLASAANDRRFVYYLLASTGICVVPLSAFCTL
KDGFRVTLLEEDEEKFNWIYKTLRDKIGEYIASA
>Mature_434_residues
MRRNIVHSGADALIYEIRQIVAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSNLILKDKSWAYTATQGYEPTRK
FLAEKVNERGGAQISADDLLFFNGLGDAVAKIFGFMRREARVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLE
DMENKVKYNDSIAGILLINPDNPTGAVYDKNLMKKIVAICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYVKSLLDAKMLEVCSTTLPQMAIPEVYSHPDFIPHLKRRNEKFKKRAHVAT
EYFAELRGVKVVEPKGAFYLTVAFDDDVLNSSMKLEIENKKADEFIQPLLASAANDRRFVYYLLASTGICVVPLSAFCTL
KDGFRVTLLEEDEEKFNWIYKTLRDKIGEYIASA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=370, Percent_Identity=25.4054054054054, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4885351, Length=367, Percent_Identity=23.9782016348774, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788627, Length=346, Percent_Identity=26.0115606936416, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71981209, Length=380, Percent_Identity=26.3157894736842, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=316, Percent_Identity=26.8987341772152, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71981215, Length=223, Percent_Identity=26.457399103139, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320317, Length=360, Percent_Identity=28.3333333333333, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323118, Length=359, Percent_Identity=28.4122562674095, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859735, Length=316, Percent_Identity=27.2151898734177, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI45551451, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641770, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641760, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641768, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641766, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24641764, Length=376, Percent_Identity=25, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 49069; Mature: 49069

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRNIVHSGADALIYEIRQIVAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSNL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
ILKDKSWAYTATQGYEPTRKFLAEKVNERGGAQISADDLLFFNGLGDAVAKIFGFMRREA
HCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHHHHHHHH
RVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLEDMENKVKYNDSIAGILLINP
HHCCCCCCHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHEECCCEEEEEEECC
DNPTGAVYDKNLMKKIVAICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEHHHHHCCCCCCHHHH
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYVKSLLDAKMLEVCSTTLPQMAIPEVYSHPD
HHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCCCC
FIPHLKRRNEKFKKRAHVATEYFAELRGVKVVEPKGAFYLTVAFDDDVLNSSMKLEIENK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECHHHHCCCEEEEECCC
KADEFIQPLLASAANDRRFVYYLLASTGICVVPLSAFCTLKDGFRVTLLEEDEEKFNWIY
CHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHEEECCCCEEEEECCCHHHHHHHH
KTLRDKIGEYIASA
HHHHHHHHHHHHCC
>Mature Secondary Structure
MRRNIVHSGADALIYEIRQIVAVAKKLEALGLQITYENIGDPILKGESIPDWMKEIVSNL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEHHHCCCCHHCCCCCHHHHHHHHHHH
ILKDKSWAYTATQGYEPTRKFLAEKVNERGGAQISADDLLFFNGLGDAVAKIFGFMRREA
HCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCEECCCCEEEECCHHHHHHHHHHHHHHHH
RVLGPSPAYSTISSAEAAHSGYEHLTYNLLPEHNWMPDLEDMENKVKYNDSIAGILLINP
HHCCCCCCHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHEECCCEEEEEEECC
DNPTGAVYDKNLMKKIVAICEKYDLMLICDETYAHVNYSDHGPLHLSEVIGDKVPGMALR
CCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCEEHHHHHCCCCCCHHHH
SISKEFPWPGGRCGWLEIFNKEKDPVFSRYVKSLLDAKMLEVCSTTLPQMAIPEVYSHPD
HHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHCCCC
FIPHLKRRNEKFKKRAHVATEYFAELRGVKVVEPKGAFYLTVAFDDDVLNSSMKLEIENK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECHHHHCCCEEEEECCC
KADEFIQPLLASAANDRRFVYYLLASTGICVVPLSAFCTLKDGFRVTLLEEDEEKFNWIY
CHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHEEECCCCEEEEECCCHHHHHHHH
KTLRDKIGEYIASA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]