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The map label for this gene is yogA [H]

Identifier: 45656846

GI number: 45656846

Start: 1154563

End: 1155576

Strand: Direct

Name: yogA [H]

Synonym: LIC10958

Alternate gene names: 45656846

Gene position: 1154563-1155576 (Clockwise)

Preceding gene: 45656845

Following gene: 45656848

Centisome position: 26.99

GC content: 38.86

Gene sequence:

>1014_bases
ATGAAAGTTTATGAAATTCAAAACCAATTTGGTCTGGAAAATTTAAAAATTTCAGAACGTCCAGATCCTGTTCCAGTACA
AGGAGAGGTACTCGTTCGTTTTAGGGCTGCTTCTTTAAATTATAGGGATTATCTAATGGCTATAGGTAGATACAATCCTA
AACAAAAATTACCTTTGATACCTCTTTCCGATGGAGCGGGTGAAGTGGTTCAAGTTGGTCCTGGAGTTACTCGTTGGAAG
ATAGGGGATAAAGTATGTGCGAACTTTGCTCAGACTTGGTTTGACGGCGCTCCGGAAAAAGATATGTTGAAAAATACTCT
AGGAGGTCCGTTAGACGGAACACTCTGTGAATATAGAATTTTTAGGGAAGAAGGTCTGGTTTTAATGCCTGAAAATCTTT
CTTTTGCAGAAGCTTCTACACTTCCTTGTGCCGCTCTGACGGCGTACACCGCGATTGTAACTCACGGAAACATACAACCG
GGAGCTACTGTAGTCGTTCAAGGAACTGGAGGTGTTTCTATATTCGCATTACAATTTGCTAAAATGATGGGATGTAGAGT
AATTGCTACTTCTTCAAGTGAGGAAAAATTAGCAAAGGTAAAAGAATTAGGAGCGGATGAAGTCATCAACTACAATGAAA
AAACAAATTGGGACAGAGAGGTTCGTAAAATAACGGAAATGAAAGGCGCCGATCTTGTCATCGAAGTCGGAGGTGCAGGT
ACTTTACAAAAATCGATTTCTAGTACTAAACCTTGGGGAACGATTGCACTGATTGGGGTTTTAGCCGGAGGAGAAAGTAA
CAACTTATCTTTATTTCCTATTTTGATGCAGGGGATTCGGATTCAGGGAATTATTGTAGGAAGTAAAAGAAACTTCGAGG
ATATGAATCTTGCAATCAATACAAACAAGATCAAACCCGTAGTGGATCAAGTTTATTCTTTTGAAGAAGTTCCTAAAGCT
TTTGAAAGCCTGAAAGCAGGAAAACATTTTGGAAAAATTTGTATCGAAATTTAA

Upstream 100 bases:

>100_bases
GTGAATTTCTTTTGAAGTTTTAAAATGGAATATAGATTATTCTTTCTACTTTTAAAATGGATAGAAAAAATAAGTCATTT
AACAAGGATAAAACGAATTT

Downstream 100 bases:

>100_bases
AATTTACTGAAAAGTTTTAGGACGAATTTTAAATTCTGGCATTTTATCAATCAGTAAGTGAGTTCTGCGTAATCTAATGC
GAAAGCGATTGATGCAGGGA

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKVYEIQNQFGLENLKISERPDPVPVQGEVLVRFRAASLNYRDYLMAIGRYNPKQKLPLIPLSDGAGEVVQVGPGVTRWK
IGDKVCANFAQTWFDGAPEKDMLKNTLGGPLDGTLCEYRIFREEGLVLMPENLSFAEASTLPCAALTAYTAIVTHGNIQP
GATVVVQGTGGVSIFALQFAKMMGCRVIATSSSEEKLAKVKELGADEVINYNEKTNWDREVRKITEMKGADLVIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNLAINTNKIKPVVDQVYSFEEVPKA
FESLKAGKHFGKICIEI

Sequences:

>Translated_337_residues
MKVYEIQNQFGLENLKISERPDPVPVQGEVLVRFRAASLNYRDYLMAIGRYNPKQKLPLIPLSDGAGEVVQVGPGVTRWK
IGDKVCANFAQTWFDGAPEKDMLKNTLGGPLDGTLCEYRIFREEGLVLMPENLSFAEASTLPCAALTAYTAIVTHGNIQP
GATVVVQGTGGVSIFALQFAKMMGCRVIATSSSEEKLAKVKELGADEVINYNEKTNWDREVRKITEMKGADLVIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNLAINTNKIKPVVDQVYSFEEVPKA
FESLKAGKHFGKICIEI
>Mature_337_residues
MKVYEIQNQFGLENLKISERPDPVPVQGEVLVRFRAASLNYRDYLMAIGRYNPKQKLPLIPLSDGAGEVVQVGPGVTRWK
IGDKVCANFAQTWFDGAPEKDMLKNTLGGPLDGTLCEYRIFREEGLVLMPENLSFAEASTLPCAALTAYTAIVTHGNIQP
GATVVVQGTGGVSIFALQFAKMMGCRVIATSSSEEKLAKVKELGADEVINYNEKTNWDREVRKITEMKGADLVIEVGGAG
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNLAINTNKIKPVVDQVYSFEEVPKA
FESLKAGKHFGKICIEI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=28.2798833819242, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=28.2798833819242, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI18379349, Length=332, Percent_Identity=27.4096385542169, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI194239674, Length=325, Percent_Identity=26.7692307692308, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI13236495, Length=325, Percent_Identity=26.7692307692308, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI34577061, Length=362, Percent_Identity=27.6243093922652, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI4501933, Length=362, Percent_Identity=27.6243093922652, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI194239676, Length=325, Percent_Identity=26.4615384615385, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI71565152, Length=351, Percent_Identity=25.3561253561254, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI156627571, Length=345, Percent_Identity=26.3768115942029, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=26.6304347826087, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI41872631, Length=326, Percent_Identity=25.4601226993865, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI47519420, Length=348, Percent_Identity=26.4367816091954, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI28557745, Length=248, Percent_Identity=30.6451612903226, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI71565154, Length=349, Percent_Identity=26.9340974212034, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI156523966, Length=353, Percent_Identity=22.3796033994334, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI4501939, Length=353, Percent_Identity=22.3796033994334, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI71743840, Length=363, Percent_Identity=22.8650137741047, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI262073058, Length=363, Percent_Identity=22.8650137741047, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1788073, Length=328, Percent_Identity=25.609756097561, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082125, Length=350, Percent_Identity=25.7142857142857, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081918, Length=324, Percent_Identity=25.3086419753086, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790485, Length=333, Percent_Identity=25.2252252252252, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788075, Length=340, Percent_Identity=25.5882352941176, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789651, Length=263, Percent_Identity=28.1368821292776, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790045, Length=333, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71988145, Length=335, Percent_Identity=25.6716417910448, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562582, Length=324, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17562584, Length=333, Percent_Identity=25.8258258258258, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17507255, Length=324, Percent_Identity=25.6172839506173, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562876, Length=269, Percent_Identity=27.8810408921933, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17562878, Length=216, Percent_Identity=25, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=225, Percent_Identity=25.7777777777778, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319621, Length=343, Percent_Identity=26.530612244898, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323729, Length=339, Percent_Identity=24.4837758112094, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=335, Percent_Identity=25.6716417910448, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324486, Length=335, Percent_Identity=25.6716417910448, Blast_Score=94, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6319955, Length=294, Percent_Identity=26.8707482993197, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6323099, Length=340, Percent_Identity=26.4705882352941, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=294, Percent_Identity=26.8707482993197, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319520, Length=339, Percent_Identity=25.0737463126844, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=356, Percent_Identity=24.438202247191, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581339, Length=379, Percent_Identity=24.802110817942, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24581341, Length=379, Percent_Identity=24.802110817942, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24581345, Length=224, Percent_Identity=28.125, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19920632, Length=224, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221330659, Length=224, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 36757; Mature: 36757

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYEIQNQFGLENLKISERPDPVPVQGEVLVRFRAASLNYRDYLMAIGRYNPKQKLPLI
CEEEEECHHCCCCCCEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCEE
PLSDGAGEVVQVGPGVTRWKIGDKVCANFAQTWFDGAPEKDMLKNTLGGPLDGTLCEYRI
ECCCCCCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHEEE
FREEGLVLMPENLSFAEASTLPCAALTAYTAIVTHGNIQPGATVVVQGTGGVSIFALQFA
EECCCCEEECCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCEEEEECCCCEEHHHHHHH
KMMGCRVIATSSSEEKLAKVKELGADEVINYNEKTNWDREVRKITEMKGADLVIEVGGAG
HHHCCEEEEECCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNLAIN
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEHHHHHCCEEEEEEEEECCCCCCCEEEEEE
TNKIKPVVDQVYSFEEVPKAFESLKAGKHFGKICIEI
CCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure
MKVYEIQNQFGLENLKISERPDPVPVQGEVLVRFRAASLNYRDYLMAIGRYNPKQKLPLI
CEEEEECHHCCCCCCEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCCCCCCCEE
PLSDGAGEVVQVGPGVTRWKIGDKVCANFAQTWFDGAPEKDMLKNTLGGPLDGTLCEYRI
ECCCCCCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCHHHEEE
FREEGLVLMPENLSFAEASTLPCAALTAYTAIVTHGNIQPGATVVVQGTGGVSIFALQFA
EECCCCEEECCCCCCCCCCCCCHHHHHHHHHHEECCCCCCCCEEEEECCCCEEHHHHHHH
KMMGCRVIATSSSEEKLAKVKELGADEVINYNEKTNWDREVRKITEMKGADLVIEVGGAG
HHHCCEEEEECCCHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCC
TLQKSISSTKPWGTIALIGVLAGGESNNLSLFPILMQGIRIQGIIVGSKRNFEDMNLAIN
HHHHHHHCCCCCCCEEEEEEEECCCCCCEEEHHHHHCCEEEEEEEEECCCCCCCEEEEEE
TNKIKPVVDQVYSFEEVPKAFESLKAGKHFGKICIEI
CCCCCHHHHHHHCHHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]