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The map label for this gene is cyaB [H]

Identifier: 45656753

GI number: 45656753

Start: 1038201

End: 1040513

Strand: Direct

Name: cyaB [H]

Synonym: LIC10862

Alternate gene names: 45656753

Gene position: 1038201-1040513 (Clockwise)

Preceding gene: 45656751

Following gene: 45656754

Centisome position: 24.27

GC content: 38.82

Gene sequence:

>2313_bases
ATGAGCGAAAAAAAAATTAAAATCACTCCACTCCACATACTGTCATTGTTGTTGGGAATAACGGGGATTCTATTTATATC
ATTTACCGCATTTTTACCTAACTTTTCGCTCAACACCGAATTCTTGCTAGGTGGATTTACCCTCTTATTGATCAGTTCGT
ATCCAATTTATAAATTTTTAGAAGTAAATACATCGGATAAACAAAAGTCGGGCAGTATTTGGTTAGCCGTAGTAGTATCG
CTTGTGATGTTTTTTCTTTATCAAGTGTTTACGCCGCTTGCAGAATTGGAAGAATCTTCCGTGTCCTGGAGATTTACATT
GCTCAGAGCGGGGGTGAATAAGAGCGAAAAAGAATCCGAAGAAGGAACGATCGAATACACGCGATATAATCCTCCGCCAG
GAGCGAGACAGGACATACAAATAATAGGAATTACAACAACGTCCTTGGAGAAGTTACAAGGGAAATGGCCGTTACCTTGG
AAATATTATGCAAATATAATAGATATATTTAAGAATACATCTAACCAGTTGATGTTCGATATTTTTTTCGTAGATTATAA
GCCGGGGCAAACCGAGGAAATGGCGCAAGCCTTGGCAAAAAATCCACAGGTAATGTTCGATTATCCGATGGAAACGAGTT
TAGAATCCAAGAGTTCCATATTAAATTTAGAAAAACGGATTGAAATACTCAGAAAATTTAAACTGGAAAACGTAGAAGAT
CCTGGGGACGCAGGACGAACTTGGTTGAAATTCCCGCAACCACCGATCGAACCAGTGGCAGAAAAAGCTTCAGGATTAGG
ATTTGCGAATATTAAAAAAGATGAAAGTGGACTCAACCGAAGAATGCCGCTGGTTGCAAAGTTAATGAATGCAGGGCCGT
TAAGAGAAACGGAATATTATCCATCCATTGATTTGATCATCGCGTGTAATTATCTAGGAGTCGATGTAAAAAGAGATGTG
GAAGTGGTAATGGGAAAATATGTCAAAATCAAAAATATACCACAAAAAACACTGACTCATTTCGATCGAAAAACCTTGAA
GATGGAAACCAAGGATATTATGAATCGACCGAATGAAAAGAGGGAGGTAGTGATACCGATCGACGCAGACGGACAGATGC
AGATCAATTTTCCTGGAGGGCTCTATTCATTTAGAGCGCATGAGATATTTGAAGCGGCGACGGAATGGAATGAGGAAACG
GCATCTCAGTTTCAAAACACAATTTTTTTAGTGGCTATGTATTATGCGACTGGAGCGGGGGCAGCAAAAGATACACACTT
GTCACCATTTGGAGATATGTCTGGGATAGAACACCACGCCGCGGCGATCAATACCATACTCAATCAGGATTTTCTATTTG
AGTTACCGTTATGGGGAGAATTTTTAATCATAATCCTTGTAGGAATGTTGGCCGGGGTTGTACAACCTAGGCTAAAGACA
TGGTTAGCGTTTTTATTTTTCTTGGCGATTGCGTTTATATATTCGGTTGGAACATTGATTAATTTTTCCGAATTTAATTT
AGTGCATTTATATCCGACTGTGATATTAGAGCAGTTATTTATATTCATTGGTTTAATAGGATTTAGGATATTAACGGAAG
AAGAAAACGTAAAGTATATACGAAGTACATTTTCCAAGTTCGTATCCAAAGACGTAGTAGATGAATTACTGAAAAATCCG
GATAACTTGAATTTAGGAGGATCTAAACGAGACATCACCATATTCTTTTCTGATATACGAGGATTTACTACCATGTCGGA
AAAAATGGGGCCGGAAGAGTTGGTTCAATTTTTGAATCAATACTTATCCGAGATGACTGAGATTATTATTGAGTTTAAGG
GAACGATTGATAAATACATGGGTGATGCGATCATGGCATTCTGGGGAGCTCCAGTGCCGTTAGAAGATCACGCTTATTAT
GGATGTGCGGCTGGGTTGGCGCAGATGAGAAGGCTCGCGACATTAAAAGAAGAGTGGAAGAGTTTAGATCTTCCACAAAT
GGATATAGGAATCGGATTAAATTCAGGGCCTGCGGTAGTAGGAAATATGGGAAGTTCTCATAGAATGGATTATACATGTA
TGGGAGATACTATCAATCTTGGCTCCAGGCTAGAAGGAACCAATAAAGAATACGGAACTCATATAATCATCTCAGAATAC
ACCTATGAAAAGGTAAAGGACAGAGTTATCGCAAGAGAACTGGACTTGATTAAAGTGAAAGGAAAAACTCAACCCGTTCG
AATCTATGAGTTATTGGATTTAGTGAACGAAGAAGACCTAAAACTATTGAGAAAACCTTTGCAGGCGAACTGA

Upstream 100 bases:

>100_bases
AAACAAACAGAACGCGAACTGGAAGTCAGCAAAATCTGGAAAATATTGACGAAACACTGACAAATAGGATACTGATCTCC
GGTCCAGATAGGAGGAACGT

Downstream 100 bases:

>100_bases
GGGATGGAATAAAATTATATTAGAAAGTTTTCATGCAACAGGAACTAACTCTGCTCGATAGAATCAACTATCCAGCTGAA
CTAAGAAATATACCACTGGA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 2; Adenylyl cyclase 2; AC2 [H]

Number of amino acids: Translated: 770; Mature: 769

Protein sequence:

>770_residues
MSEKKIKITPLHILSLLLGITGILFISFTAFLPNFSLNTEFLLGGFTLLLISSYPIYKFLEVNTSDKQKSGSIWLAVVVS
LVMFFLYQVFTPLAELEESSVSWRFTLLRAGVNKSEKESEEGTIEYTRYNPPPGARQDIQIIGITTTSLEKLQGKWPLPW
KYYANIIDIFKNTSNQLMFDIFFVDYKPGQTEEMAQALAKNPQVMFDYPMETSLESKSSILNLEKRIEILRKFKLENVED
PGDAGRTWLKFPQPPIEPVAEKASGLGFANIKKDESGLNRRMPLVAKLMNAGPLRETEYYPSIDLIIACNYLGVDVKRDV
EVVMGKYVKIKNIPQKTLTHFDRKTLKMETKDIMNRPNEKREVVIPIDADGQMQINFPGGLYSFRAHEIFEAATEWNEET
ASQFQNTIFLVAMYYATGAGAAKDTHLSPFGDMSGIEHHAAAINTILNQDFLFELPLWGEFLIIILVGMLAGVVQPRLKT
WLAFLFFLAIAFIYSVGTLINFSEFNLVHLYPTVILEQLFIFIGLIGFRILTEEENVKYIRSTFSKFVSKDVVDELLKNP
DNLNLGGSKRDITIFFSDIRGFTTMSEKMGPEELVQFLNQYLSEMTEIIIEFKGTIDKYMGDAIMAFWGAPVPLEDHAYY
GCAAGLAQMRRLATLKEEWKSLDLPQMDIGIGLNSGPAVVGNMGSSHRMDYTCMGDTINLGSRLEGTNKEYGTHIIISEY
TYEKVKDRVIARELDLIKVKGKTQPVRIYELLDLVNEEDLKLLRKPLQAN

Sequences:

>Translated_770_residues
MSEKKIKITPLHILSLLLGITGILFISFTAFLPNFSLNTEFLLGGFTLLLISSYPIYKFLEVNTSDKQKSGSIWLAVVVS
LVMFFLYQVFTPLAELEESSVSWRFTLLRAGVNKSEKESEEGTIEYTRYNPPPGARQDIQIIGITTTSLEKLQGKWPLPW
KYYANIIDIFKNTSNQLMFDIFFVDYKPGQTEEMAQALAKNPQVMFDYPMETSLESKSSILNLEKRIEILRKFKLENVED
PGDAGRTWLKFPQPPIEPVAEKASGLGFANIKKDESGLNRRMPLVAKLMNAGPLRETEYYPSIDLIIACNYLGVDVKRDV
EVVMGKYVKIKNIPQKTLTHFDRKTLKMETKDIMNRPNEKREVVIPIDADGQMQINFPGGLYSFRAHEIFEAATEWNEET
ASQFQNTIFLVAMYYATGAGAAKDTHLSPFGDMSGIEHHAAAINTILNQDFLFELPLWGEFLIIILVGMLAGVVQPRLKT
WLAFLFFLAIAFIYSVGTLINFSEFNLVHLYPTVILEQLFIFIGLIGFRILTEEENVKYIRSTFSKFVSKDVVDELLKNP
DNLNLGGSKRDITIFFSDIRGFTTMSEKMGPEELVQFLNQYLSEMTEIIIEFKGTIDKYMGDAIMAFWGAPVPLEDHAYY
GCAAGLAQMRRLATLKEEWKSLDLPQMDIGIGLNSGPAVVGNMGSSHRMDYTCMGDTINLGSRLEGTNKEYGTHIIISEY
TYEKVKDRVIARELDLIKVKGKTQPVRIYELLDLVNEEDLKLLRKPLQAN
>Mature_769_residues
SEKKIKITPLHILSLLLGITGILFISFTAFLPNFSLNTEFLLGGFTLLLISSYPIYKFLEVNTSDKQKSGSIWLAVVVSL
VMFFLYQVFTPLAELEESSVSWRFTLLRAGVNKSEKESEEGTIEYTRYNPPPGARQDIQIIGITTTSLEKLQGKWPLPWK
YYANIIDIFKNTSNQLMFDIFFVDYKPGQTEEMAQALAKNPQVMFDYPMETSLESKSSILNLEKRIEILRKFKLENVEDP
GDAGRTWLKFPQPPIEPVAEKASGLGFANIKKDESGLNRRMPLVAKLMNAGPLRETEYYPSIDLIIACNYLGVDVKRDVE
VVMGKYVKIKNIPQKTLTHFDRKTLKMETKDIMNRPNEKREVVIPIDADGQMQINFPGGLYSFRAHEIFEAATEWNEETA
SQFQNTIFLVAMYYATGAGAAKDTHLSPFGDMSGIEHHAAAINTILNQDFLFELPLWGEFLIIILVGMLAGVVQPRLKTW
LAFLFFLAIAFIYSVGTLINFSEFNLVHLYPTVILEQLFIFIGLIGFRILTEEENVKYIRSTFSKFVSKDVVDELLKNPD
NLNLGGSKRDITIFFSDIRGFTTMSEKMGPEELVQFLNQYLSEMTEIIIEFKGTIDKYMGDAIMAFWGAPVPLEDHAYYG
CAAGLAQMRRLATLKEEWKSLDLPQMDIGIGLNSGPAVVGNMGSSHRMDYTCMGDTINLGSRLEGTNKEYGTHIIISEYT
YEKVKDRVIARELDLIKVKGKTQPVRIYELLDLVNEEDLKLLRKPLQAN

Specific function: Unknown

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI134152694, Length=158, Percent_Identity=35.4430379746835, Blast_Score=67, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17534665, Length=155, Percent_Identity=38.7096774193548, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212645647, Length=157, Percent_Identity=38.2165605095541, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71989822, Length=153, Percent_Identity=31.3725490196078, Blast_Score=73, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71989805, Length=153, Percent_Identity=31.3725490196078, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17534659, Length=176, Percent_Identity=31.25, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508769, Length=176, Percent_Identity=28.9772727272727, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161078020, Length=186, Percent_Identity=31.7204301075269, Blast_Score=80, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28574512, Length=194, Percent_Identity=31.9587628865979, Blast_Score=76, Evalue=8e-14,
Organism=Drosophila melanogaster, GI161076872, Length=194, Percent_Identity=31.9587628865979, Blast_Score=76, Evalue=9e-14,
Organism=Drosophila melanogaster, GI62484477, Length=221, Percent_Identity=29.8642533936652, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI62484298, Length=221, Percent_Identity=29.8642533936652, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116008008, Length=221, Percent_Identity=29.8642533936652, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281366459, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281366457, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281366455, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI56292422, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI56292424, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666940, Length=173, Percent_Identity=30.635838150289, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI221330470, Length=154, Percent_Identity=33.7662337662338, Blast_Score=69, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330468, Length=154, Percent_Identity=33.7662337662338, Blast_Score=68, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00072 Response_reg [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 87382; Mature: 87251

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKKIKITPLHILSLLLGITGILFISFTAFLPNFSLNTEFLLGGFTLLLISSYPIYKFL
CCCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
EVNTSDKQKSGSIWLAVVVSLVMFFLYQVFTPLAELEESSVSWRFTLLRAGVNKSEKESE
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCC
EGTIEYTRYNPPPGARQDIQIIGITTTSLEKLQGKWPLPWKYYANIIDIFKNTSNQLMFD
CCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
IFFVDYKPGQTEEMAQALAKNPQVMFDYPMETSLESKSSILNLEKRIEILRKFKLENVED
EEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDAGRTWLKFPQPPIEPVAEKASGLGFANIKKDESGLNRRMPLVAKLMNAGPLRETEYY
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
PSIDLIIACNYLGVDVKRDVEVVMGKYVKIKNIPQKTLTHFDRKTLKMETKDIMNRPNEK
CCEEEEEEECCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
REVVIPIDADGQMQINFPGGLYSFRAHEIFEAATEWNEETASQFQNTIFLVAMYYATGAG
CEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCCC
AAKDTHLSPFGDMSGIEHHAAAINTILNQDFLFELPLWGEFLIIILVGMLAGVVQPRLKT
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WLAFLFFLAIAFIYSVGTLINFSEFNLVHLYPTVILEQLFIFIGLIGFRILTEEENVKYI
HHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
RSTFSKFVSKDVVDELLKNPDNLNLGGSKRDITIFFSDIRGFTTMSEKMGPEELVQFLNQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHH
YLSEMTEIIIEFKGTIDKYMGDAIMAFWGAPVPLEDHAYYGCAAGLAQMRRLATLKEEWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLDLPQMDIGIGLNSGPAVVGNMGSSHRMDYTCMGDTINLGSRLEGTNKEYGTHIIISEY
HCCCCCEEECCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
TYEKVKDRVIARELDLIKVKGKTQPVRIYELLDLVNEEDLKLLRKPLQAN
HHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SEKKIKITPLHILSLLLGITGILFISFTAFLPNFSLNTEFLLGGFTLLLISSYPIYKFL
CCCCEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEE
EVNTSDKQKSGSIWLAVVVSLVMFFLYQVFTPLAELEESSVSWRFTLLRAGVNKSEKESE
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHCCCCCCCCCC
EGTIEYTRYNPPPGARQDIQIIGITTTSLEKLQGKWPLPWKYYANIIDIFKNTSNQLMFD
CCCEEEEEECCCCCCCCCEEEEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
IFFVDYKPGQTEEMAQALAKNPQVMFDYPMETSLESKSSILNLEKRIEILRKFKLENVED
EEEEECCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PGDAGRTWLKFPQPPIEPVAEKASGLGFANIKKDESGLNRRMPLVAKLMNAGPLRETEYY
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCC
PSIDLIIACNYLGVDVKRDVEVVMGKYVKIKNIPQKTLTHFDRKTLKMETKDIMNRPNEK
CCEEEEEEECCCCCCHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
REVVIPIDADGQMQINFPGGLYSFRAHEIFEAATEWNEETASQFQNTIFLVAMYYATGAG
CEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEEEHHCCCC
AAKDTHLSPFGDMSGIEHHAAAINTILNQDFLFELPLWGEFLIIILVGMLAGVVQPRLKT
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WLAFLFFLAIAFIYSVGTLINFSEFNLVHLYPTVILEQLFIFIGLIGFRILTEEENVKYI
HHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHHHHHHHHHHHHHEEECCCCCHHHH
RSTFSKFVSKDVVDELLKNPDNLNLGGSKRDITIFFSDIRGFTTMSEKMGPEELVQFLNQ
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCHHHHHHCCCHHHHHHHHHH
YLSEMTEIIIEFKGTIDKYMGDAIMAFWGAPVPLEDHAYYGCAAGLAQMRRLATLKEEWK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SLDLPQMDIGIGLNSGPAVVGNMGSSHRMDYTCMGDTINLGSRLEGTNKEYGTHIIISEY
HCCCCCEEECCCCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEECC
TYEKVKDRVIARELDLIKVKGKTQPVRIYELLDLVNEEDLKLLRKPLQAN
HHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]