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The map label for this gene is frr

Identifier: 45656744

GI number: 45656744

Start: 1028735

End: 1029289

Strand: Direct

Name: frr

Synonym: LIC10853

Alternate gene names: 45656744

Gene position: 1028735-1029289 (Clockwise)

Preceding gene: 45656743

Following gene: 45656745

Centisome position: 24.05

GC content: 40.9

Gene sequence:

>555_bases
ATGGCAAGTGATGCAATCATTTCTGGAATGAAAACTAAGATGGATAAAACCATCGATCTTGTAAAAAAGGATTTCGGAAC
CATTCGTACTGGACGCGCTAATCCCTCTCTTGTAGAAGATATTCGAGTGGATTATTACGGGAATCAAACTCCGATCAATC
AGCTTGGAAATATTTCCGTTCCGGAACCTAGAATGCTGGTCATTTCTCCTTATGATAAGGGAATTATGAAAGACATCGAA
AAGGCGATCCAAACTTCCGGTTTAGGTCTTCAACCTACCAATGACGGGGTAGTGATTCGAATCGTAATTCCGGAACTAAC
AGGGGAAAGGCGAAAGGAACTTGCAAAAGTTGTAAAGTCTAAATCCGAGGAAAAAAAGGTCGCCATCCGGAACATCCGTA
GAGACGCGATGGAAGATCTTAAAAAACATACCGAAGGGATGTCTCAAGACGAGATCAAATCGGTTCAAGATCAGATTCAA
AAAATCACAGATTCCTATATCGATAAAATTTCCGCTCTTACCGCAGAGAAGGAAAAGGAAATCACTACGATCTAA

Upstream 100 bases:

>100_bases
ATTATAGTGTTCGACATCTTCAAACGTGGAAATCTCAAAGACCTGGTTACCGGTAAAAACATCGGCACATTGATCTCTAA
TTCGGAGGACATTCAAATCG

Downstream 100 bases:

>100_bases
CGTGGGCTTGTTCGAGTCCAATCTCCCGAAACATATTGCCGTTATTATGGATGGTAACGGTCGTTGGGCAACATCCCGAG
GTAAATCCAGATCGGAAGGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISVPEPRMLVISPYDKGIMKDIE
KAIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKSKSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQ
KITDSYIDKISALTAEKEKEITTI

Sequences:

>Translated_184_residues
MASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISVPEPRMLVISPYDKGIMKDIE
KAIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKSKSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQ
KITDSYIDKISALTAEKEKEITTI
>Mature_183_residues
ASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISVPEPRMLVISPYDKGIMKDIEK
AIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKSKSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQK
ITDSYIDKISALTAEKEKEITTI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another [H]

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family [H]

Homologues:

Organism=Homo sapiens, GI20270317, Length=171, Percent_Identity=28.6549707602339, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI291042689, Length=132, Percent_Identity=31.0606060606061, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1786368, Length=171, Percent_Identity=43.859649122807, Blast_Score=148, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24661488, Length=177, Percent_Identity=28.8135593220339, Blast_Score=83, Evalue=1e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002661
- InterPro:   IPR015998 [H]

Pfam domain/function: PF01765 RRF [H]

EC number: NA

Molecular weight: Translated: 20601; Mature: 20470

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCC
PEPRMLVISPYDKGIMKDIEKAIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKS
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHC
KSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQKITDSYIDKISALTAEKEKE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITTI
CCCC
>Mature Secondary Structure 
ASDAIISGMKTKMDKTIDLVKKDFGTIRTGRANPSLVEDIRVDYYGNQTPINQLGNISV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHCCCCCC
PEPRMLVISPYDKGIMKDIEKAIQTSGLGLQPTNDGVVIRIVIPELTGERRKELAKVVKS
CCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHC
KSEEKKVAIRNIRRDAMEDLKKHTEGMSQDEIKSVQDQIQKITDSYIDKISALTAEKEKE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ITTI
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA