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The map label for this gene is atoS [H]

Identifier: 45656697

GI number: 45656697

Start: 975553

End: 977691

Strand: Direct

Name: atoS [H]

Synonym: LIC10806

Alternate gene names: 45656697

Gene position: 975553-977691 (Clockwise)

Preceding gene: 45656696

Following gene: 45656700

Centisome position: 22.81

GC content: 39.13

Gene sequence:

>2139_bases
ATGACAAACGTAAAAAACCATTCAAGATTTTCCGCTTATTATTTGGGACAATGGATATTTGGAATTGGTACAATTTTAGT
GATTGTATCCTTTTTTGGTAATTATTATTACAAAGAAAAAAATATAGACAGGCTCATCGATAATATCCACTGGACTGTTT
CTTATCTTTGTGCGGCGGCTTTAGCCTGGCTGGGTTGTTTTTCGGTTGAGGCGGCCGGAATTTACCGTTTTCGGTTTTGG
TTTGCACTTGGTCTTACTGCAAACGCGCTTGGACAATTATCTTGGGCGATTCAAGTTTATTTTAATTATTACATGACCCC
AACCCCGAGCGATTTTCTTTTTCCGTGGGTCGCTCCTTGTTTTATCATAGGATACTCTATTATAGTTATTGAATGCGATC
GAAATAAAATCAGAGTGGCGGCATTAGACGCTCTTGGTCTTATTACAGCAGTTCTCACATTTTCACTCGCGTTGTATCTT
CCTCAAAGAGAAGGGGTTGGAATTGCGCAACTTCTTCCGTTGATCAATCATCCGGTTTCTTTTTTGACTGCTGCCGCTTT
GGGAATTTTACTGATTCCCGTTCTAAGATTGCAACCAAATAAGTCTTGGTTGTCGTTTATAGTTGGCATGGGAGGAAGTG
GTTTTTGTTGGTTGTTATGGAATGCGTTGTTTATCGTTGAAATTCCTCCCGACGGGACCGTTCTCAATGCTGGTTTTTCT
ATTTCAACTTTAATCTTGGGATATGGAGTTTGGACCTGGGAACCTAAATTGAATGATCATCCGATTTGGGGAAGAAGATT
TGAAGCGGCGCTTCGTCTATTACCATTATTTGAAGTGGTTGCGAGTTCGGTTACGATCGTATTAGCAGGAACTCTTAGCG
GTTTACCGGAAGGGGTTCGAATCGTTGCATGGACTGGAACTACGATTGTGGTTCTAATTGCGAGTGTGAGACAAACCTTA
CTCGTTAAGGAGATGACTGATGCGGAACAGGAAATCCGTTTAGTCAATGAAGGGCTCGAAGAGATAGTCGCTAAACGGAC
CGAAGAGCTTAGAACTGTAAATCAATATCTTATTTCTAAAAATGAACAAGTGATTAGAGCAATCGCAAACTTGAAAAACG
CACAGAAACAACTCGTTCGTTCTGAAAAGATGGCTGTGCTTGGACAATTGGTTGCGGGAATTGCACACGAACTAAATACT
CCGTTAGGCGCCATTGTTTCTTCTAATGAAGCCATTCAGTTGGTATTGTCCAACTCTTGGGAAGGTCTGCTTAGGAATTA
TTCTGATTTTACCGAAGATGAAAAAGTAATTTGGAAAAAACTTTTTTCAAAAGGAATTACTCTCAGAGAGTTTTACGATA
CGAGAGAAGAGAGAACTAAAAGAAAAAAAATAGCAATTTTGTTAAACGACTTCGGATTTTCCGAAGCGACTCGTCTTGCG
GATATTCTTACCGATCTGGGGATTCATCCAGATTATGTATTAGAAAATTTTAAATATTTAAGTCAAAAAGAAAGATTACT
TCTGATCGCGCAAAATGCTTTATCTCTTTCAGGTCTTGCCAGAGCGAGTTTTACAATTGAAAAAGCTGCTGAAAAAGCTT
CTTTAGTAATACAAGCCCTAAAGGAATATGCGTATAGAGATCGTAGTGAAACTGCTATGAGTCCTGTAGATGTACGAAAG
CAATTGGAAACCGTACTGACTCTTTATTATTCTAAATACAAAACTCAAGTAGAGATTGTTCGTGAAATGCCGGAAACTTC
CTACGTTCAGGGGAATGCGGAATCTCTTACACAAGTATGGACAAATCTGATCGGAAACGCTCTTTATTCGATGGGATATA
AAGGGAAAATTGAAATCTCTTGTAAAAGAGTTTCTACTACTTGGGAAGTAGCAATTAAGGATAGTGGGGCAGGAATCGAA
GAATCGATCAAAGATAGAATTTTCGAACCCTTTTTTACTACAAAACCTTCCGGTGCGGGAACGGGTTTAGGTTTGGACAT
CTGTAGAAGAATCATAGAAGATCATAATGGCAAAATCTATTTTGAAACTTCTAAAGAAGGAACTACATTTTTTGTGATCC
TCCCCGCCTCGGAACCGGTTTTGCAAAAACTCGAAACTCAAATCAGTAAAAATCAGTAA

Upstream 100 bases:

>100_bases
TATTATATAAACTGTTTTTGTTTTGAGAATCTTTGAAGCTAGAAAAAGATCGACGAAATCGGCGCTTAACTCTTAAGCTG
TCGTCGTCCCTGGACAATCG

Downstream 100 bases:

>100_bases
ATTCTATTTTATTAATATAGATTGACCTTTCTTTTTGATTTCTTCTGCGTCTTTTTTATGATCTACTTTATTTGGTATAT
CTTTGCCCTTAATAAAGGCA

Product: histidine kinase sensor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MTNVKNHSRFSAYYLGQWIFGIGTILVIVSFFGNYYYKEKNIDRLIDNIHWTVSYLCAAALAWLGCFSVEAAGIYRFRFW
FALGLTANALGQLSWAIQVYFNYYMTPTPSDFLFPWVAPCFIIGYSIIVIECDRNKIRVAALDALGLITAVLTFSLALYL
PQREGVGIAQLLPLINHPVSFLTAAALGILLIPVLRLQPNKSWLSFIVGMGGSGFCWLLWNALFIVEIPPDGTVLNAGFS
ISTLILGYGVWTWEPKLNDHPIWGRRFEAALRLLPLFEVVASSVTIVLAGTLSGLPEGVRIVAWTGTTIVVLIASVRQTL
LVKEMTDAEQEIRLVNEGLEEIVAKRTEELRTVNQYLISKNEQVIRAIANLKNAQKQLVRSEKMAVLGQLVAGIAHELNT
PLGAIVSSNEAIQLVLSNSWEGLLRNYSDFTEDEKVIWKKLFSKGITLREFYDTREERTKRKKIAILLNDFGFSEATRLA
DILTDLGIHPDYVLENFKYLSQKERLLLIAQNALSLSGLARASFTIEKAAEKASLVIQALKEYAYRDRSETAMSPVDVRK
QLETVLTLYYSKYKTQVEIVREMPETSYVQGNAESLTQVWTNLIGNALYSMGYKGKIEISCKRVSTTWEVAIKDSGAGIE
ESIKDRIFEPFFTTKPSGAGTGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASEPVLQKLETQISKNQ

Sequences:

>Translated_712_residues
MTNVKNHSRFSAYYLGQWIFGIGTILVIVSFFGNYYYKEKNIDRLIDNIHWTVSYLCAAALAWLGCFSVEAAGIYRFRFW
FALGLTANALGQLSWAIQVYFNYYMTPTPSDFLFPWVAPCFIIGYSIIVIECDRNKIRVAALDALGLITAVLTFSLALYL
PQREGVGIAQLLPLINHPVSFLTAAALGILLIPVLRLQPNKSWLSFIVGMGGSGFCWLLWNALFIVEIPPDGTVLNAGFS
ISTLILGYGVWTWEPKLNDHPIWGRRFEAALRLLPLFEVVASSVTIVLAGTLSGLPEGVRIVAWTGTTIVVLIASVRQTL
LVKEMTDAEQEIRLVNEGLEEIVAKRTEELRTVNQYLISKNEQVIRAIANLKNAQKQLVRSEKMAVLGQLVAGIAHELNT
PLGAIVSSNEAIQLVLSNSWEGLLRNYSDFTEDEKVIWKKLFSKGITLREFYDTREERTKRKKIAILLNDFGFSEATRLA
DILTDLGIHPDYVLENFKYLSQKERLLLIAQNALSLSGLARASFTIEKAAEKASLVIQALKEYAYRDRSETAMSPVDVRK
QLETVLTLYYSKYKTQVEIVREMPETSYVQGNAESLTQVWTNLIGNALYSMGYKGKIEISCKRVSTTWEVAIKDSGAGIE
ESIKDRIFEPFFTTKPSGAGTGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASEPVLQKLETQISKNQ
>Mature_711_residues
TNVKNHSRFSAYYLGQWIFGIGTILVIVSFFGNYYYKEKNIDRLIDNIHWTVSYLCAAALAWLGCFSVEAAGIYRFRFWF
ALGLTANALGQLSWAIQVYFNYYMTPTPSDFLFPWVAPCFIIGYSIIVIECDRNKIRVAALDALGLITAVLTFSLALYLP
QREGVGIAQLLPLINHPVSFLTAAALGILLIPVLRLQPNKSWLSFIVGMGGSGFCWLLWNALFIVEIPPDGTVLNAGFSI
STLILGYGVWTWEPKLNDHPIWGRRFEAALRLLPLFEVVASSVTIVLAGTLSGLPEGVRIVAWTGTTIVVLIASVRQTLL
VKEMTDAEQEIRLVNEGLEEIVAKRTEELRTVNQYLISKNEQVIRAIANLKNAQKQLVRSEKMAVLGQLVAGIAHELNTP
LGAIVSSNEAIQLVLSNSWEGLLRNYSDFTEDEKVIWKKLFSKGITLREFYDTREERTKRKKIAILLNDFGFSEATRLAD
ILTDLGIHPDYVLENFKYLSQKERLLLIAQNALSLSGLARASFTIEKAAEKASLVIQALKEYAYRDRSETAMSPVDVRKQ
LETVLTLYYSKYKTQVEIVREMPETSYVQGNAESLTQVWTNLIGNALYSMGYKGKIEISCKRVSTTWEVAIKDSGAGIEE
SIKDRIFEPFFTTKPSGAGTGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASEPVLQKLETQISKNQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=171, Percent_Identity=33.9181286549708, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=114, Percent_Identity=37.719298245614, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=153, Percent_Identity=28.7581699346405, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1788393, Length=148, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79858; Mature: 79726

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVKNHSRFSAYYLGQWIFGIGTILVIVSFFGNYYYKEKNIDRLIDNIHWTVSYLCAAA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHH
LAWLGCFSVEAAGIYRFRFWFALGLTANALGQLSWAIQVYFNYYMTPTPSDFLFPWVAPC
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHH
FIIGYSIIVIECDRNKIRVAALDALGLITAVLTFSLALYLPQREGVGIAQLLPLINHPVS
HHHCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHH
FLTAAALGILLIPVLRLQPNKSWLSFIVGMGGSGFCWLLWNALFIVEIPPDGTVLNAGFS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHEECCEEEEEECCCCCEEECCCH
ISTLILGYGVWTWEPKLNDHPIWGRRFEAALRLLPLFEVVASSVTIVLAGTLSGLPEGVR
HHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCE
IVAWTGTTIVVLIASVRQTLLVKEMTDAEQEIRLVNEGLEEIVAKRTEELRTVNQYLISK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEQVIRAIANLKNAQKQLVRSEKMAVLGQLVAGIAHELNTPLGAIVSSNEAIQLVLSNSW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCH
EGLLRNYSDFTEDEKVIWKKLFSKGITLREFYDTREERTKRKKIAILLNDFGFSEATRLA
HHHHHCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHH
DILTDLGIHPDYVLENFKYLSQKERLLLIAQNALSLSGLARASFTIEKAAEKASLVIQAL
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEYAYRDRSETAMSPVDVRKQLETVLTLYYSKYKTQVEIVREMPETSYVQGNAESLTQVW
HHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TNLIGNALYSMGYKGKIEISCKRVSTTWEVAIKDSGAGIEESIKDRIFEPFFTTKPSGAG
HHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
TGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASEPVLQKLETQISKNQ
CCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNVKNHSRFSAYYLGQWIFGIGTILVIVSFFGNYYYKEKNIDRLIDNIHWTVSYLCAAA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHH
LAWLGCFSVEAAGIYRFRFWFALGLTANALGQLSWAIQVYFNYYMTPTPSDFLFPWVAPC
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHH
FIIGYSIIVIECDRNKIRVAALDALGLITAVLTFSLALYLPQREGVGIAQLLPLINHPVS
HHHCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHH
FLTAAALGILLIPVLRLQPNKSWLSFIVGMGGSGFCWLLWNALFIVEIPPDGTVLNAGFS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHEECCEEEEEECCCCCEEECCCH
ISTLILGYGVWTWEPKLNDHPIWGRRFEAALRLLPLFEVVASSVTIVLAGTLSGLPEGVR
HHHHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCE
IVAWTGTTIVVLIASVRQTLLVKEMTDAEQEIRLVNEGLEEIVAKRTEELRTVNQYLISK
EEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NEQVIRAIANLKNAQKQLVRSEKMAVLGQLVAGIAHELNTPLGAIVSSNEAIQLVLSNSW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCEEEEEECCCH
EGLLRNYSDFTEDEKVIWKKLFSKGITLREFYDTREERTKRKKIAILLNDFGFSEATRLA
HHHHHCHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHH
DILTDLGIHPDYVLENFKYLSQKERLLLIAQNALSLSGLARASFTIEKAAEKASLVIQAL
HHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
KEYAYRDRSETAMSPVDVRKQLETVLTLYYSKYKTQVEIVREMPETSYVQGNAESLTQVW
HHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TNLIGNALYSMGYKGKIEISCKRVSTTWEVAIKDSGAGIEESIKDRIFEPFFTTKPSGAG
HHHHHHHHHHCCCCCEEEEEEEEECCEEEEEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
TGLGLDICRRIIEDHNGKIYFETSKEGTTFFVILPASEPVLQKLETQISKNQ
CCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]