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The map label for this gene is yggV [C]

Identifier: 45656447

GI number: 45656447

Start: 672486

End: 673079

Strand: Reverse

Name: yggV [C]

Synonym: LIC10549

Alternate gene names: 45656447

Gene position: 673079-672486 (Counterclockwise)

Preceding gene: 45656448

Following gene: 45656446

Centisome position: 15.74

GC content: 37.37

Gene sequence:

>594_bases
TTGAAGCGACAACTCGCTCTCGGCACAAACAACTTAAACAAAGTAAAAGAAGTAAGCTCCATTCTCATGGAGTTAGGAAT
TCAGATCCTTACGCCTAAGGATCTGAAAGTTTCTTTTAACCCTGAAGAAACAGGTTCTACATTTAAAGAAAACGCTCTCA
TCAAAGCGAAAGAATTGTTTTATTTAACTAAAATTCCTTCAATTGCGGATGACTCTGGAATTTGTGTTTCTGCTCTCAAA
GATGAACCTGGGGTTTATTCGGCTCGATTTGGAGGTCCGGAACTGAATGATGAAGGTAGAGCACTTCTTCTTTTAGAAAA
ACTGAAAGGGAATCAAAATCGCAAGGCCTATTATGCTTGTGCGATCGCTTATGTGGACGAATCTACTGAACAAAGTTTCG
AAGGTAGATGTGAAGGATTGATCTCAGAAGAATATGATAGAATTGGAATATATGGTTTTGGATACGATCCAATTTTCATT
TTCCCGCCGCTTCAAAAACCTTTTTCACAAATCCAAGAAGAAACAAAGAACTCAGTCTCTCATAGAAAAAAAGCCTTAGA
CGAGCTTTTGAAATTTCTTAAAACGAAACCATAA

Upstream 100 bases:

>100_bases
ATGAAGATCTGTTGCAACTTTTCGAAATCACGATGTTAGACAAGGTTTTTAAAATAGTTCCGAATATCGAAGATGCATTC
GATGAATTTAAACTAAACCC

Downstream 100 bases:

>100_bases
AAATCTATTTGAGTCCAAAACCTAAAAAGCTTAGGTATTCTTATAACGGCAAAAGGATATTTAAAAATGTCTTCGTTTAA
CCTATACTCGGACGCATAAA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELFYLTKIPSIADDSGICVSALK
DEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFI
FPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP

Sequences:

>Translated_197_residues
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELFYLTKIPSIADDSGICVSALK
DEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFI
FPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP
>Mature_197_residues
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELFYLTKIPSIADDSGICVSALK
DEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYACAIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFI
FPPLQKPFSQIQEETKNSVSHRKKALDELLKFLKTKP

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=38.5786802030457, Blast_Score=136, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17556833, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=29.7872340425532, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_LEPIC (Q72UV8)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_000533.1
- ProteinModelPortal:   Q72UV8
- SMR:   Q72UV8
- GeneID:   2772736
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC10549
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- ProtClustDB:   PRK00120
- BioCyc:   LINT267671:LIC_10549-MONOMER
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 22106; Mature: 22106

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELF
CCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHCCCEEHHHHE
YLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYAC
EECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEE
AIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFIFPPLQKPFSQIQEETKNSVS
EEEEECCCHHHHHHHHHHHCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
HRKKALDELLKFLKTKP
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRQLALGTNNLNKVKEVSSILMELGIQILTPKDLKVSFNPEETGSTFKENALIKAKELF
CCCEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCEEEECCCCCCCHHHHCCCEEHHHHE
YLTKIPSIADDSGICVSALKDEPGVYSARFGGPELNDEGRALLLLEKLKGNQNRKAYYAC
EECCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCCCEEEEE
AIAYVDESTEQSFEGRCEGLISEEYDRIGIYGFGYDPIFIFPPLQKPFSQIQEETKNSVS
EEEEECCCHHHHHHHHHHHCHHCCCCEEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHH
HRKKALDELLKFLKTKP
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA