| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
Click here to switch to the map view.
The map label for this gene is lepB
Identifier: 45656376
GI number: 45656376
Start: 552136
End: 552732
Strand: Reverse
Name: lepB
Synonym: LIC10478
Alternate gene names: 45656376
Gene position: 552732-552136 (Counterclockwise)
Preceding gene: 45656377
Following gene: 45656374
Centisome position: 12.92
GC content: 35.01
Gene sequence:
>597_bases TTGTCTTACGTTAATATGAAAAGTATCATAATGCAAAAAAGTACGAGAAAGTATCTACGCGTTATTCTACCCATATTTCT TTCTTTATTTACAATTCTTCTAATACGAATTTTTTTATTTCAAATCTACTTCATCTCAGGTTATTCTATGGCTCCTTCTT ACAAAGAAGGGGATTTAATCTTAGTTACCAAGTTTGGGTTTCCAACCCGTATCGGAAAGTGGGAAATATCTTTTGTTGAA AGTAAAGTGAATCGTTTCGACGTTCTCGTTTTGGATGGATTTGAAGAAGAACTAAGTCTAAAAAGAGTCGTCGGATTACC AGGTGATTATTTTCGTTTTGAAAACGATCGGATTCTAATCAACGATTCTCCTCTACAAGAAACATTTTTAAAACCTGGAT TTAAAACCATCGCACCTTCTCTTTCCATGATCCCTATGACTGCAGCTAAAGGAAATGTTCCAATCGGAGACACTGGTAGA ATTCCTCCGGGCTATTTTTTAATGTTAGGTGATAACCGTGAAAACTCTACAGATTCTAGGAATTACGGCTTGGTCCCATT CCAAAAATTACGAGGTAGAGTTTGGATTTTTTTATAA
Upstream 100 bases:
>100_bases ACTATAATTAAAAGTCCTAAAGTACATTTACGTTTCACGGAAATTCAATCCCGCTAAAAAACCTTTTTCGATTTGCCACG TTCAGGAAGATTTTTAAACA
Downstream 100 bases:
>100_bases ATCTCAGCCCGAATGATTATTTTTTTCAATATTAGAGTTGTTGAAAAATGAATCCTCCATCTTGTTTCAATTTCATGAAA TGGTCGATTAAAGCAGCTTT
Product: signal peptidase I
Products: NA
Alternate protein names: SPase I; Leader peptidase I [H]
Number of amino acids: Translated: 198; Mature: 197
Protein sequence:
>198_residues MSYVNMKSIIMQKSTRKYLRVILPIFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKFGFPTRIGKWEISFVE SKVNRFDVLVLDGFEEELSLKRVVGLPGDYFRFENDRILINDSPLQETFLKPGFKTIAPSLSMIPMTAAKGNVPIGDTGR IPPGYFLMLGDNRENSTDSRNYGLVPFQKLRGRVWIFL
Sequences:
>Translated_198_residues MSYVNMKSIIMQKSTRKYLRVILPIFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKFGFPTRIGKWEISFVE SKVNRFDVLVLDGFEEELSLKRVVGLPGDYFRFENDRILINDSPLQETFLKPGFKTIAPSLSMIPMTAAKGNVPIGDTGR IPPGYFLMLGDNRENSTDSRNYGLVPFQKLRGRVWIFL >Mature_197_residues SYVNMKSIIMQKSTRKYLRVILPIFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLILVTKFGFPTRIGKWEISFVES KVNRFDVLVLDGFEEELSLKRVVGLPGDYFRFENDRILINDSPLQETFLKPGFKTIAPSLSMIPMTAAKGNVPIGDTGRI PPGYFLMLGDNRENSTDSRNYGLVPFQKLRGRVWIFL
Specific function: Unknown
COG id: COG0681
COG function: function code U; Signal peptidase I
Gene ontology:
Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S26 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000223 - InterPro: IPR019758 - InterPro: IPR019757 - InterPro: IPR019756 - InterPro: IPR019759 - InterPro: IPR015927 - InterPro: IPR011056 [H]
Pfam domain/function: PF00717 Peptidase_S24 [H]
EC number: =3.4.21.89 [H]
Molecular weight: Translated: 22772; Mature: 22641
Theoretical pI: Translated: 10.10; Mature: 10.10
Prosite motif: PS00761 SPASE_I_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.5 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 3.0 %Met (Mature Protein) 3.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSYVNMKSIIMQKSTRKYLRVILPIFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLI CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE LVTKFGFPTRIGKWEISFVESKVNRFDVLVLDGFEEELSLKRVVGLPGDYFRFENDRILI EEEECCCCCCCCCEEEHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCHHEEEECCEEEE NDSPLQETFLKPGFKTIAPSLSMIPMTAAKGNVPIGDTGRIPPGYFLMLGDNRENSTDSR CCCCHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC NYGLVPFQKLRGRVWIFL CCCCCCHHHHCCEEEEEC >Mature Secondary Structure SYVNMKSIIMQKSTRKYLRVILPIFLSLFTILLIRIFLFQIYFISGYSMAPSYKEGDLI CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEE LVTKFGFPTRIGKWEISFVESKVNRFDVLVLDGFEEELSLKRVVGLPGDYFRFENDRILI EEEECCCCCCCCCEEEHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCHHEEEECCEEEE NDSPLQETFLKPGFKTIAPSLSMIPMTAAKGNVPIGDTGRIPPGYFLMLGDNRENSTDSR CCCCHHHHHHCCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC NYGLVPFQKLRGRVWIFL CCCCCCHHHHCCEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 8801417 [H]