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The map label for this gene is glmM [H]

Identifier: 45656345

GI number: 45656345

Start: 509862

End: 511244

Strand: Reverse

Name: glmM [H]

Synonym: LIC10446

Alternate gene names: 45656345

Gene position: 511244-509862 (Counterclockwise)

Preceding gene: 45656346

Following gene: 45656344

Centisome position: 11.95

GC content: 40.64

Gene sequence:

>1383_bases
ATGAATACAAAAATTCCCGTATTCAATCATCCGGATTTAATGGTCTCTGTTTCCGGAATCCGAGGAATCATTCCCACTGG
ACTTTCTCCCGAGGTAATCTTTAATTCACTACGCGCCTTCGGAACTTGGATCGAAGGTTCCAAAATCGTAATTGGCCGGG
ACTCTAGACCTTCCGGATCTTACCTCGAAAACATCGCTCTGGGTCTAATGCAAGCAATGGGAAAAGAAGTATTACAACTT
GGAATTGTTCCAACTCCCACAGTAAAAGCGGTGGTCAATCTATCTAAAGCGGGAGGTGGAATTATGATCAGCGCCTCTCA
CAATCCAATTATCTGGAATGCGTTTAAATTTATAGGACCAGGCGGTTTTTTTACAAATGCATCCGACCTAGAACAAATAC
TAGAAACGGTTCAAAATCAATCCTATAAACCAATACAATACAAACCTTCTTCTAAAATCGTTTTCGGAACAGAATGGTCC
GAAAAACACATCGAGTCAGTCCTCAAACGAGTCGACGTAAACTCAATTCGAAAGAAAAAATATAAGGTTCTTATAGACTC
AGTAAACGGAGCTGGAAGTTATTTAGTTCCTGAACTTCTGGAAAAACTAGGATGTAAACCAATTCTTTTACACTGCGTTC
CGGACGGAACCTTCCCCAGACCTCCAGAACCAACTCCGGAAGCACTCAAACAAACTTCTCGTAAAATGAAATCTTCAGGA
GCAGATATAGGATTTGCTCTGGACCCCGACGCAGATCGTCTCGTAGTTCTCACTCCTAAAAAAGGTGCAATCTCCGAAGA
ATATACTCTTCCACTGAGTTTTCTTTCTCTAACTTTGGAAAAAATTCCTAAAAAGGCAAACATAGTCGTAAATCTTTCTA
CAAGTTTTATCAACGAATTTGTAGCCAGACAAAACGGAGTTCCTGTATTTCGTTCTAAAGTAGGAGAAGCAAATGTAGTT
TCCGAAATGCTCCGCCAAAAATCGATTTTCGGAGGAGAAGGAAACGGTGGAGTCATCGACCCAACAATTGCATCCTTTGG
AAGAGATTCTCTTTCCGGAATTGCACATATCTTAAACGTTATGGCTGCGACCGGAAAAAAGATCGATTCTATCGTAGAAG
AACTTCCTGCAATTTATATGCAAAAAACGAGTTTTAAAATCGCAGGTAAAAATCTTCAAGACATCTATTCTAAATTCCGT
GGAGAATTTTCTACCTTCTCCGAAGAAACAATAGACGGACTTCGTTTAACTTCCGAAGATTCTTGGATTCATATTCGTCC
TTCTAATACAGAACCAATCATTCGAATTATAGGCGAAGCGAGGACTAAAAAAGACCTCAATTCTCTGCTGGACCGCGCAG
GAAGACTCATGGAGAATGCCTGA

Upstream 100 bases:

>100_bases
CGATTAGCTCAGCTGGTAGAGCGCCTGCCTTACAAGCAGGATGTCGGCAGTTCGATCCTGTCATCGCCCATAATCCTTTT
CCGGAGCAACTCAAACCTCT

Downstream 100 bases:

>100_bases
ATATGTGTGGAATCGTCGGTTATGCAGGTAAAAAAAACGCGGAATCGGTACTAGTCGTAGGATTAATCTGTCTCGAATAC
AGAGGTTATGATTCTGCAGG

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MNTKIPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNSLRAFGTWIEGSKIVIGRDSRPSGSYLENIALGLMQAMGKEVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPIIWNAFKFIGPGGFFTNASDLEQILETVQNQSYKPIQYKPSSKIVFGTEWS
EKHIESVLKRVDVNSIRKKKYKVLIDSVNGAGSYLVPELLEKLGCKPILLHCVPDGTFPRPPEPTPEALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLEKIPKKANIVVNLSTSFINEFVARQNGVPVFRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPTIASFGRDSLSGIAHILNVMAATGKKIDSIVEELPAIYMQKTSFKIAGKNLQDIYSKFR
GEFSTFSEETIDGLRLTSEDSWIHIRPSNTEPIIRIIGEARTKKDLNSLLDRAGRLMENA

Sequences:

>Translated_460_residues
MNTKIPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNSLRAFGTWIEGSKIVIGRDSRPSGSYLENIALGLMQAMGKEVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPIIWNAFKFIGPGGFFTNASDLEQILETVQNQSYKPIQYKPSSKIVFGTEWS
EKHIESVLKRVDVNSIRKKKYKVLIDSVNGAGSYLVPELLEKLGCKPILLHCVPDGTFPRPPEPTPEALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLEKIPKKANIVVNLSTSFINEFVARQNGVPVFRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPTIASFGRDSLSGIAHILNVMAATGKKIDSIVEELPAIYMQKTSFKIAGKNLQDIYSKFR
GEFSTFSEETIDGLRLTSEDSWIHIRPSNTEPIIRIIGEARTKKDLNSLLDRAGRLMENA
>Mature_460_residues
MNTKIPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNSLRAFGTWIEGSKIVIGRDSRPSGSYLENIALGLMQAMGKEVLQL
GIVPTPTVKAVVNLSKAGGGIMISASHNPIIWNAFKFIGPGGFFTNASDLEQILETVQNQSYKPIQYKPSSKIVFGTEWS
EKHIESVLKRVDVNSIRKKKYKVLIDSVNGAGSYLVPELLEKLGCKPILLHCVPDGTFPRPPEPTPEALKQTSRKMKSSG
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLEKIPKKANIVVNLSTSFINEFVARQNGVPVFRSKVGEANVV
SEMLRQKSIFGGEGNGGVIDPTIASFGRDSLSGIAHILNVMAATGKKIDSIVEELPAIYMQKTSFKIAGKNLQDIYSKFR
GEFSTFSEETIDGLRLTSEDSWIHIRPSNTEPIIRIIGEARTKKDLNSLLDRAGRLMENA

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=436, Percent_Identity=26.1467889908257, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789566, Length=453, Percent_Identity=25.8278145695364, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.10 [H]

Molecular weight: Translated: 50239; Mature: 50239

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKIPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNSLRAFGTWIEGSKIVIGRDSRPSGS
CCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCEECCCEEEEECCCCCCCH
YLENIALGLMQAMGKEVLQLGIVPTPTVKAVVNLSKAGGGIMISASHNPIIWNAFKFIGP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHCC
GGFFTNASDLEQILETVQNQSYKPIQYKPSSKIVFGTEWSEKHIESVLKRVDVNSIRKKK
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHH
YKVLIDSVNGAGSYLVPELLEKLGCKPILLHCVPDGTFPRPPEPTPEALKQTSRKMKSSG
HEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLEKIPKKANIVVNLSTSFINEF
CCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
VARQNGVPVFRSKVGEANVVSEMLRQKSIFGGEGNGGVIDPTIASFGRDSLSGIAHILNV
HHHCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHH
MAATGKKIDSIVEELPAIYMQKTSFKIAGKNLQDIYSKFRGEFSTFSEETIDGLRLTSED
HHHCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCC
SWIHIRPSNTEPIIRIIGEARTKKDLNSLLDRAGRLMENA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTKIPVFNHPDLMVSVSGIRGIIPTGLSPEVIFNSLRAFGTWIEGSKIVIGRDSRPSGS
CCCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCEECCCEEEEECCCCCCCH
YLENIALGLMQAMGKEVLQLGIVPTPTVKAVVNLSKAGGGIMISASHNPIIWNAFKFIGP
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEEEHHHHHCC
GGFFTNASDLEQILETVQNQSYKPIQYKPSSKIVFGTEWSEKHIESVLKRVDVNSIRKKK
CCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHH
YKVLIDSVNGAGSYLVPELLEKLGCKPILLHCVPDGTFPRPPEPTPEALKQTSRKMKSSG
HEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
ADIGFALDPDADRLVVLTPKKGAISEEYTLPLSFLSLTLEKIPKKANIVVNLSTSFINEF
CCEEEEECCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHH
VARQNGVPVFRSKVGEANVVSEMLRQKSIFGGEGNGGVIDPTIASFGRDSLSGIAHILNV
HHHCCCCCHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEECCHHHHCCCHHHHHHHHHHHH
MAATGKKIDSIVEELPAIYMQKTSFKIAGKNLQDIYSKFRGEFSTFSEETIDGLRLTSED
HHHCCHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHCCCHHHHHHHHHCCEEEECCC
SWIHIRPSNTEPIIRIIGEARTKKDLNSLLDRAGRLMENA
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]