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The map label for this gene is 45656343

Identifier: 45656343

GI number: 45656343

Start: 506975

End: 508021

Strand: Reverse

Name: 45656343

Synonym: LIC10444

Alternate gene names: NA

Gene position: 508021-506975 (Counterclockwise)

Preceding gene: 45656344

Following gene: 45656342

Centisome position: 11.88

GC content: 39.26

Gene sequence:

>1047_bases
ATGCCCAAGGTTCAGAGAATTCTCATCGATGAAAGAGAGGTTCCGGCTGGTTTACGATCCTTAACTCGCATTCGATCTTT
TTCCGAAATTCGAAACGGAATTCTGAATACGATCCAAAGAACGAAAGAAATTTATCAAGACGCGAAAATTTTTTATGCTC
ACTCTAACTCAGCCTTTCAACAAGCCTTCTTAGAAAGAAATCCAAAACTTCTTCCTTACGATGAAAAAGACGTAGACTTG
ATATTATCTTCCGAGTCTTGTCTTCCTTGGAACTCAATCGATGGAATTGCAAAAAATATAGAAGTTGATCTAGAACTCAG
TAAAGACGTTCGAAAATGGATTCGAAAACTCAAAGTAAAATCGAATCATTTCCACGTAGTCGGAAAATCAAAACATTTGC
ATGTTCATCCGTCCGCAACCGTTTATCCAGGAGTTGTGTTCGATACAACGTCTGGACCGGTGATTGTTGACAAGGACGTA
AAAATCACTTCATTCTCGTTCATCGAAGGTCCGGTTTATATAGGACCAAATTCCCACATAGACAATGCAAGAATTACAGG
AGCCACAAGTATCGGAACAACTTGTAGAATCGGAGGAGAAGTCGGAACCTGTTTGATCGGAGATTTTACGAACAAACATC
ACGAAGGATTTTTAGGGCATTCCGTTTTAGGAAACTGGGTAAATATAGGAGCGCTTGCAACCACATCCGATTTAAAGAAC
AATTACGGTGTCGTAAAAATTAGAGAAGAACAAGACGAATGTATTACAGGTTCTATTAAGTTCGGTTCAGTCATCGGAGA
TTATTGTAAGATCGCAATCGGAGTAATGTTAAATACCGGAACCGTGATAGACTTTGGATCCAATGTAGTATCGTCCAGAA
TCGGAGGCTACATTTCACCTTTCACCTGGGCTGAATCAGGACAACCTTATATTCTCGATCTATTTTTAAGGGACGCACGT
AAGATCATGGCGAGAAGGAACCGAGAGTTAACGTTATCCGAAACTGAATTGATCCGTATATTATACGAATCTAAAGTAAA
AAAATAA

Upstream 100 bases:

>100_bases
TTCCTCTTCAATTACTCGCTTATTACTCAGCGATCGCTAGAGGTTGTCCTCCGGATCAACCTAGAAACCTTGCTAAGTCC
GTAACCGTAGAGTAACTACC

Downstream 100 bases:

>100_bases
AAATCCGGAGGGTTTTGTGGAAATCATAGAATCCAAAATACGTACGTCTTCATCAGAGTATAAAGAAAATTTCGAAGATC
TCAAACAAAAGGTGGAATCC

Product: glucose-1-phosphate thymidylyltransferase

Products: diphosphate; dTDPglucose

Alternate protein names: Nucleotidyl Transferase; Sugar Phosphate Nucleotydyl Transferase; Sugar Phospate Transferase; Transferase Hexapeptide Repeat Containing Protein; Nucleoside-Diphosphate-Sugar Pyrophosphorylase; UDP-N-Acetylglucosamine Diphosphorylase; Transferase Hexapeptide Repeat; Glucose-1-Phosphate Thymidylyltransferase-Like Protein; Sugar Nucleotidyltransferase; Sugar-1-Phosphate Guanyl Transferase; Hexapeptide Transferase Family Protein; Transferase LpxA Family; Bacterial Transferase Hexapeptide Repeat Protein; Hexapeptide Repeat-Containing Protein; Sugar-Phosphate Nucleotydyltransferase

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MPKVQRILIDEREVPAGLRSLTRIRSFSEIRNGILNTIQRTKEIYQDAKIFYAHSNSAFQQAFLERNPKLLPYDEKDVDL
ILSSESCLPWNSIDGIAKNIEVDLELSKDVRKWIRKLKVKSNHFHVVGKSKHLHVHPSATVYPGVVFDTTSGPVIVDKDV
KITSFSFIEGPVYIGPNSHIDNARITGATSIGTTCRIGGEVGTCLIGDFTNKHHEGFLGHSVLGNWVNIGALATTSDLKN
NYGVVKIREEQDECITGSIKFGSVIGDYCKIAIGVMLNTGTVIDFGSNVVSSRIGGYISPFTWAESGQPYILDLFLRDAR
KIMARRNRELTLSETELIRILYESKVKK

Sequences:

>Translated_348_residues
MPKVQRILIDEREVPAGLRSLTRIRSFSEIRNGILNTIQRTKEIYQDAKIFYAHSNSAFQQAFLERNPKLLPYDEKDVDL
ILSSESCLPWNSIDGIAKNIEVDLELSKDVRKWIRKLKVKSNHFHVVGKSKHLHVHPSATVYPGVVFDTTSGPVIVDKDV
KITSFSFIEGPVYIGPNSHIDNARITGATSIGTTCRIGGEVGTCLIGDFTNKHHEGFLGHSVLGNWVNIGALATTSDLKN
NYGVVKIREEQDECITGSIKFGSVIGDYCKIAIGVMLNTGTVIDFGSNVVSSRIGGYISPFTWAESGQPYILDLFLRDAR
KIMARRNRELTLSETELIRILYESKVKK
>Mature_347_residues
PKVQRILIDEREVPAGLRSLTRIRSFSEIRNGILNTIQRTKEIYQDAKIFYAHSNSAFQQAFLERNPKLLPYDEKDVDLI
LSSESCLPWNSIDGIAKNIEVDLELSKDVRKWIRKLKVKSNHFHVVGKSKHLHVHPSATVYPGVVFDTTSGPVIVDKDVK
ITSFSFIEGPVYIGPNSHIDNARITGATSIGTTCRIGGEVGTCLIGDFTNKHHEGFLGHSVLGNWVNIGALATTSDLKNN
YGVVKIREEQDECITGSIKFGSVIGDYCKIAIGVMLNTGTVIDFGSNVVSSRIGGYISPFTWAESGQPYILDLFLRDARK
IMARRNRELTLSETELIRILYESKVKK

Specific function: Unknown

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.7.24

Molecular weight: Translated: 38825; Mature: 38694

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKVQRILIDEREVPAGLRSLTRIRSFSEIRNGILNTIQRTKEIYQDAKIFYAHSNSAFQ
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHH
QAFLERNPKLLPYDEKDVDLILSSESCLPWNSIDGIAKNIEVDLELSKDVRKWIRKLKVK
HHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCEEEEEEECHHHHHHHHHHHCC
SNHFHVVGKSKHLHVHPSATVYPGVVFDTTSGPVIVDKDVKITSFSFIEGPVYIGPNSHI
CCEEEEEECCCEEEECCCCEECCCEEEECCCCCEEEECCCEEEEEEEECCCEEECCCCCC
DNARITGATSIGTTCRIGGEVGTCLIGDFTNKHHEGFLGHSVLGNWVNIGALATTSDLKN
CCCEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHCCCEECCEEEEHHHHCC
NYGVVKIREEQDECITGSIKFGSVIGDYCKIAIGVMLNTGTVIDFGSNVVSSRIGGYISP
CCCEEEEECCCCCEEECCEEHHHHHHHHHHHEEEEEEECCEEEECCCHHHHHHHCCCCCC
FTWAESGQPYILDLFLRDARKIMARRNRELTLSETELIRILYESKVKK
CEECCCCCCEEEHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PKVQRILIDEREVPAGLRSLTRIRSFSEIRNGILNTIQRTKEIYQDAKIFYAHSNSAFQ
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHH
QAFLERNPKLLPYDEKDVDLILSSESCLPWNSIDGIAKNIEVDLELSKDVRKWIRKLKVK
HHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHCEEEEEEECHHHHHHHHHHHCC
SNHFHVVGKSKHLHVHPSATVYPGVVFDTTSGPVIVDKDVKITSFSFIEGPVYIGPNSHI
CCEEEEEECCCEEEECCCCEECCCEEEECCCCCEEEECCCEEEEEEEECCCEEECCCCCC
DNARITGATSIGTTCRIGGEVGTCLIGDFTNKHHEGFLGHSVLGNWVNIGALATTSDLKN
CCCEEECCCCCCCEEEECCCCCEEEEECCCCCCCCCCCCHHHHCCCEECCEEEEHHHHCC
NYGVVKIREEQDECITGSIKFGSVIGDYCKIAIGVMLNTGTVIDFGSNVVSSRIGGYISP
CCCEEEEECCCCCEEECCEEHHHHHHHHHHHEEEEEEECCEEEECCCHHHHHHHCCCCCC
FTWAESGQPYILDLFLRDARKIMARRNRELTLSETELIRILYESKVKK
CEECCCCCCEEEHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTTP; alpha-D-glucose 1-phosphate

Specific reaction: dTTP + alpha-D-glucose 1-phosphate = diphosphate + dTDP-glucose

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA