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The map label for this gene is hypB [H]

Identifier: 45359083

GI number: 45359083

Start: 1479677

End: 1480351

Strand: Direct

Name: hypB [H]

Synonym: MMP1520

Alternate gene names: 45359083

Gene position: 1479677-1480351 (Clockwise)

Preceding gene: 45359077

Following gene: 45359088

Centisome position: 89.08

GC content: 33.48

Gene sequence:

>675_bases
ATGCATTTTGTTGATGTTTTGAATATAGGAAAAGACATAATTAAAGCAAATAATAAGAACGCAGATAAAAACAGGAAAAT
ATTAGAAGATCACGGAATCGTGGCATTTGACTTTATGGGCGCAATTGGAAGCGGTAAAACTCTTTTAATTGAAAAATTAA
TCAATGAATTAAAAGACGAATACAAAATTGCGTGTATTGCCGGAGATGTTATTGCAAAATACGATGCTGGAAGAATGGAA
AAGCATGGTGTTAAAGTTATTCCATTAAATACGGGTAAAGAATGCCACCTCGATGCACACCAGATTGGACACTGTTTCCA
CGACTTAGACCTTGATAATTTGGACATTATTTTTATCGAAAACGTTGGAAACTTGATATGTCCAACAGATTTTGATTTAG
GAACGCACAAACGAACTGTTGTTGTGAGTGTCACCGAAGGAGACGACACCGTTGAAAAACACCCTGAAATCTTCAAAACA
GCTAATTTAACCATAATTAACAAAATAGATATTTCAGAAGCTGTTGGTGCTGATCCGCAAAAAATGTTAAATGATGCAAA
AAAAATTAATAAAGATATGGAAGTTCTTCTAACTGCCATAAAACATGACAACGGCGTTTCAGATGTTGTTAACTTCATTA
AAAAAACAATTGAAGAAGTAAAAGCCCAAAAATAA

Upstream 100 bases:

>100_bases
ATAACTGCTTAATCGTTTTTCAAATAATACATATTTTTATAAAATAAGATTTGAAATTAACTATACTTCTAACATATGGC
TAGTTTTAGGGTGATAATTC

Downstream 100 bases:

>100_bases
TTATATAAACATTGATTTTATTTTTTTTAAATTGCCATTACTTCGACAAATTTTGGATCTTTTGAAACTTTTTCATACCA
CATGCTAATTCCGATATAAA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MHFVDVLNIGKDIIKANNKNADKNRKILEDHGIVAFDFMGAIGSGKTLLIEKLINELKDEYKIACIAGDVIAKYDAGRME
KHGVKVIPLNTGKECHLDAHQIGHCFHDLDLDNLDIIFIENVGNLICPTDFDLGTHKRTVVVSVTEGDDTVEKHPEIFKT
ANLTIINKIDISEAVGADPQKMLNDAKKINKDMEVLLTAIKHDNGVSDVVNFIKKTIEEVKAQK

Sequences:

>Translated_224_residues
MHFVDVLNIGKDIIKANNKNADKNRKILEDHGIVAFDFMGAIGSGKTLLIEKLINELKDEYKIACIAGDVIAKYDAGRME
KHGVKVIPLNTGKECHLDAHQIGHCFHDLDLDNLDIIFIENVGNLICPTDFDLGTHKRTVVVSVTEGDDTVEKHPEIFKT
ANLTIINKIDISEAVGADPQKMLNDAKKINKDMEVLLTAIKHDNGVSDVVNFIKKTIEEVKAQK
>Mature_224_residues
MHFVDVLNIGKDIIKANNKNADKNRKILEDHGIVAFDFMGAIGSGKTLLIEKLINELKDEYKIACIAGDVIAKYDAGRME
KHGVKVIPLNTGKECHLDAHQIGHCFHDLDLDNLDIIFIENVGNLICPTDFDLGTHKRTVVVSVTEGDDTVEKHPEIFKT
ANLTIINKIDISEAVGADPQKMLNDAKKINKDMEVLLTAIKHDNGVSDVVNFIKKTIEEVKAQK

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=209, Percent_Identity=36.3636363636364, Blast_Score=151, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 24849; Mature: 24849

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFVDVLNIGKDIIKANNKNADKNRKILEDHGIVAFDFMGAIGSGKTLLIEKLINELKDE
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
YKIACIAGDVIAKYDAGRMEKHGVKVIPLNTGKECHLDAHQIGHCFHDLDLDNLDIIFIE
HEEEEEECCHHHHCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
NVGNLICPTDFDLGTHKRTVVVSVTEGDDTVEKHPEIFKTANLTIINKIDISEAVGADPQ
CCCCEECCCCCCCCCCCEEEEEEEECCCCHHHHCCHHHHHCCEEEEEEECCHHHHCCCHH
KMLNDAKKINKDMEVLLTAIKHDNGVSDVVNFIKKTIEEVKAQK
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHFVDVLNIGKDIIKANNKNADKNRKILEDHGIVAFDFMGAIGSGKTLLIEKLINELKDE
CCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHHHH
YKIACIAGDVIAKYDAGRMEKHGVKVIPLNTGKECHLDAHQIGHCFHDLDLDNLDIIFIE
HEEEEEECCHHHHCCCCCHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEE
NVGNLICPTDFDLGTHKRTVVVSVTEGDDTVEKHPEIFKTANLTIINKIDISEAVGADPQ
CCCCEECCCCCCCCCCCEEEEEEEECCCCHHHHCCHHHHHCCEEEEEEECCHHHHCCCHH
KMLNDAKKINKDMEVLLTAIKHDNGVSDVVNFIKKTIEEVKAQK
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]