Click here to switch to the map view.

The map label for this gene is manB [H]

Identifier: 45358935

GI number: 45358935

Start: 1353065

End: 1354378

Strand: Direct

Name: manB [H]

Synonym: MMP1372

Alternate gene names: 45358935

Gene position: 1353065-1354378 (Clockwise)

Preceding gene: 45358934

Following gene: 45358937

Centisome position: 81.45

GC content: 29.76

Gene sequence:

>1314_bases
TTGGTATTTAAGGCATACGACATCAGGGGAATTTATGAAAAAGATTTAGATGATAATTTTGCTTATTCTTTAGGAAAACT
CGTTGGAAAAAAATATGAAAGAATAATGGTTGGAAACGATATTCGAATCGGTTCCAAAAAACTCTTAAAACCATTTATTT
ACGGGATACTTGAAAATTCTAAAGTTTACTATGCTGGAGAAATCTCAACCCCGCTGATGTACTTTGGAACTCTTAAAAAA
TTCGATCTTGGAGTAATTTTAACTGCATCCCACAATCCAAAAGAATATACTGGATTTAAAATGTGCGACATTGATGCAAT
TCCACTCTCCCCAGTAGATGAAATAAAACCAGATTTTGAAATGTTTGAACTTTCAGAAGAACAAAAGGAAGAAATTGAAA
ATTTGGATTTAGAAAGATTAAATGTTGATATTTTAAGTGAATATTTGAATTTTTTTACCCAAAAACTTGAAAAAACGAAC
CGAAAAATTGCAGTAGACTTTGCAAACGGTGCAACTACTAATGCAGAAAAACAGGTTTTAAAAAAAGTTTTAGAAAATAA
AATATTTGTTAACGATTTTCCGGACGGAAATTTCCCTGCACACGAACCAGACACTCTTAAAAAAGAATGTTTAATCGACA
TTATAAATAGTGTAAAATCCAATTCCTGCGAATTTGGCCTTATTTTTGATGGAGATGGCGACAGAATTGGAATGGTTGAT
GAAAAGGGAGAAATTTTAGCAGGAGATATATTAACTGCGATAATTTCAAATGAAATTTTAAACGAAGTCAAAGGAAAAAT
TGTATACGATTTGAGATGCAGTAAAGTAGTTCCTGAAACAATTTCAAAAAATGGAGGAACTCCAGTAAAAACAAGAGTTG
GACACTACTTCATAAAAAAATTGATGCATGAAATAGATGCTGAATTTGCAGGGGAGTTTAGCAATCACTTCTACTTCAAA
TCAACAGGTTACTTTGAAAGCCCGTTATTAGCATTGAATTATATCCTAAAAGCAATTGAAAGAGAAGGAAAACCACTTTC
AGAAATTTCGAAAAATTACAAAAAATATTTTCACAGTGGTGAAATAAACTTTAAAGTAGCTGACCAAAAAAAATCAATTG
AATCTATTGAAAAAAAATATGAAAACATCTGTAAAATCGAAAAATTAGATGGAATTTCTCTTTATTGTAATGATTTTTGG
TTTAATGTTAGATCATCAAATACTGAACCACTTTTAAGGTTAAATTTAGAAGCAGAAGATGAAAAAACAATGAATGAGAA
ATTAACAGAAATAAAAGAGATAATTAATTCTTAA

Upstream 100 bases:

>100_bases
ATGGTATAATATTTTTTATTTTTTTGAAAAGTTATTTAATCCCAATTTACATAATATAACGCATAGATTTTTTTATTCGA
ACATTGAACGGTGGTTTAAG

Downstream 100 bases:

>100_bases
ATTTTAAATAACTTTGAAAATTCCAAAAATACTTTTTTTAAAAAATAAAAATTAGATTTAATTTAGGATATAACCTTGTC
AATCATGTCGAGTTCGAGTG

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MVFKAYDIRGIYEKDLDDNFAYSLGKLVGKKYERIMVGNDIRIGSKKLLKPFIYGILENSKVYYAGEISTPLMYFGTLKK
FDLGVILTASHNPKEYTGFKMCDIDAIPLSPVDEIKPDFEMFELSEEQKEEIENLDLERLNVDILSEYLNFFTQKLEKTN
RKIAVDFANGATTNAEKQVLKKVLENKIFVNDFPDGNFPAHEPDTLKKECLIDIINSVKSNSCEFGLIFDGDGDRIGMVD
EKGEILAGDILTAIISNEILNEVKGKIVYDLRCSKVVPETISKNGGTPVKTRVGHYFIKKLMHEIDAEFAGEFSNHFYFK
STGYFESPLLALNYILKAIEREGKPLSEISKNYKKYFHSGEINFKVADQKKSIESIEKKYENICKIEKLDGISLYCNDFW
FNVRSSNTEPLLRLNLEAEDEKTMNEKLTEIKEIINS

Sequences:

>Translated_437_residues
MVFKAYDIRGIYEKDLDDNFAYSLGKLVGKKYERIMVGNDIRIGSKKLLKPFIYGILENSKVYYAGEISTPLMYFGTLKK
FDLGVILTASHNPKEYTGFKMCDIDAIPLSPVDEIKPDFEMFELSEEQKEEIENLDLERLNVDILSEYLNFFTQKLEKTN
RKIAVDFANGATTNAEKQVLKKVLENKIFVNDFPDGNFPAHEPDTLKKECLIDIINSVKSNSCEFGLIFDGDGDRIGMVD
EKGEILAGDILTAIISNEILNEVKGKIVYDLRCSKVVPETISKNGGTPVKTRVGHYFIKKLMHEIDAEFAGEFSNHFYFK
STGYFESPLLALNYILKAIEREGKPLSEISKNYKKYFHSGEINFKVADQKKSIESIEKKYENICKIEKLDGISLYCNDFW
FNVRSSNTEPLLRLNLEAEDEKTMNEKLTEIKEIINS
>Mature_437_residues
MVFKAYDIRGIYEKDLDDNFAYSLGKLVGKKYERIMVGNDIRIGSKKLLKPFIYGILENSKVYYAGEISTPLMYFGTLKK
FDLGVILTASHNPKEYTGFKMCDIDAIPLSPVDEIKPDFEMFELSEEQKEEIENLDLERLNVDILSEYLNFFTQKLEKTN
RKIAVDFANGATTNAEKQVLKKVLENKIFVNDFPDGNFPAHEPDTLKKECLIDIINSVKSNSCEFGLIFDGDGDRIGMVD
EKGEILAGDILTAIISNEILNEVKGKIVYDLRCSKVVPETISKNGGTPVKTRVGHYFIKKLMHEIDAEFAGEFSNHFYFK
STGYFESPLLALNYILKAIEREGKPLSEISKNYKKYFHSGEINFKVADQKKSIESIEKKYENICKIEKLDGISLYCNDFW
FNVRSSNTEPLLRLNLEAEDEKTMNEKLTEIKEIINS

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=447, Percent_Identity=32.2147651006711, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1789566, Length=456, Percent_Identity=26.3157894736842, Blast_Score=108, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 49999; Mature: 49999

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFKAYDIRGIYEKDLDDNFAYSLGKLVGKKYERIMVGNDIRIGSKKLLKPFIYGILENS
CEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCC
KVYYAGEISTPLMYFGTLKKFDLGVILTASHNPKEYTGFKMCDIDAIPLSPVDEIKPDFE
EEEEECCCCCCHHHHHCHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHCCCCHH
MFELSEEQKEEIENLDLERLNVDILSEYLNFFTQKLEKTNRKIAVDFANGATTNAEKQVL
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
KKVLENKIFVNDFPDGNFPAHEPDTLKKECLIDIINSVKSNSCEFGLIFDGDGDRIGMVD
HHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEC
EKGEILAGDILTAIISNEILNEVKGKIVYDLRCSKVVPETISKNGGTPVKTRVGHYFIKK
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHH
LMHEIDAEFAGEFSNHFYFKSTGYFESPLLALNYILKAIEREGKPLSEISKNYKKYFHSG
HHHHHCHHHHCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
EINFKVADQKKSIESIEKKYENICKIEKLDGISLYCNDFWFNVRSSNTEPLLRLNLEAED
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCEEEEECCCCC
EKTMNEKLTEIKEIINS
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVFKAYDIRGIYEKDLDDNFAYSLGKLVGKKYERIMVGNDIRIGSKKLLKPFIYGILENS
CEEEEEECCCCHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHCCC
KVYYAGEISTPLMYFGTLKKFDLGVILTASHNPKEYTGFKMCDIDAIPLSPVDEIKPDFE
EEEEECCCCCCHHHHHCHHHCCCCEEEECCCCCCCCCCEEEEECCCCCCCCHHHCCCCHH
MFELSEEQKEEIENLDLERLNVDILSEYLNFFTQKLEKTNRKIAVDFANGATTNAEKQVL
HHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHH
KKVLENKIFVNDFPDGNFPAHEPDTLKKECLIDIINSVKSNSCEFGLIFDGDGDRIGMVD
HHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEC
EKGEILAGDILTAIISNEILNEVKGKIVYDLRCSKVVPETISKNGGTPVKTRVGHYFIKK
CCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHHH
LMHEIDAEFAGEFSNHFYFKSTGYFESPLLALNYILKAIEREGKPLSEISKNYKKYFHSG
HHHHHCHHHHCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
EINFKVADQKKSIESIEKKYENICKIEKLDGISLYCNDFWFNVRSSNTEPLLRLNLEAED
CEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECEEEEECCCCCCCEEEEECCCCC
EKTMNEKLTEIKEIINS
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]