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The map label for this gene is yciR [C]

Identifier: 37680869

GI number: 37680869

Start: 2724134

End: 2726197

Strand: Direct

Name: yciR [C]

Synonym: VV2685

Alternate gene names: 37680869

Gene position: 2724134-2726197 (Clockwise)

Preceding gene: 37680859

Following gene: 37680874

Centisome position: 81.21

GC content: 45.49

Gene sequence:

>2064_bases
ATGCTTAGAAACAAAAAAGTGCATTCATTAGCTTTCAAGCAAGCCAGAACCGTTTTTCTGGTTTCCGTTGTATTGGGACT
GTGTTTCAGCTTGTACCACATTTTGGCTGATCTGCACCAAGAGCAACGCCGTATTGAAGAGCACTACCAGTTTAAGCTGC
TGCAAAACTATTCCAATGCCAGCCAAGCCGCATATCATCTGAATCATCTGCTCGCCGAGCAGGTTGCCTCGACCCTAATG
ATGGACAATGCCATCTACCGAGTAAAAATCGTCGACGATTTTGGAGACGTGCTGACCCAAAAGCACCGTGAAATTGACTC
TCAGAGCCTAACAACTCAGTTGTTGTCTAAAATACTGACCCCCGCTCAACCGTTTTACAAAACAGAACTTCACCAACCCA
ACGCCAATGCAATTGTTGGTGAATTGAGTTTCTCGGTTGATGGCTCTAGCATCGCCGATGCCTTTATTAAGAAATCGACT
CGAATTGTCTTGTTCGATCTGTTTCGCAATATATTACTCACCTCTATCTTGTTGTTTTTCTTTTACTTTAAGCTATCAAA
GCCCATTATCACGCTGATTAATTGGGTGAATTCGCTGCAAAATCGAAAAAATGCCTTGGAACTGCCTCCCGGTAACAACA
ATGATGAACTGGGTCGACTCGCGCTTTCATTTCACAATCTCTGGCAAGCGCGCGCGGCAGCAGAAAGTCAGCTCAACCAA
TTGGCTTACTTCGATACCCTAACAGGCTTAGCCAACCGCAGCTTGCTGCTAAAAAGCCTCAATGAAACCCTTAAAGAGTC
ACAAAGCGAGCAATACCCAGGAGTACTGTTTTATCTCGACCTCGACCGTTTCAAAACCATTAACGACTCCCTAGGGCATA
CTATTGGTGACAACTTAATGCGCACCATTGCGAAACGCCTAGAAGCATGGCTACAACCCGGAGAAATTGCCGCACGCATT
GGTGGGGATGAGTTCGCCATTTTGATCCCGAAACTCAATAAAGAAGATGCCGCCAACAAAGCGAAGCAGTTGCTCACCTT
GATCTCAAACCCTTATTCCATTGACGATCACCAGCTTTATTGCACGGTCAGTATTGGTATTTCCACGTTTGCCGACAAAG
GCATCTCGAGCATTGATGTGCTCCGTCAGGCCGATACGGCGCTCTATCGCGCCAAAGTCGCCGGACGCAATAAATACATG
TTTTATGAGCCAGAAATGCAGGCGCAAGTGGAGTCTTTTTTGGAGATAGAGAAAGGGCTGCATGAAGCACTGCACAAAGG
GCAACTTGAGCTTTACTACCAACCTCAGGTCAACGCGCAGCAACAAATTATCGGAGTGGAAGCCCTCATCCGTTGGAACC
ATCCAGAAAAAGGCGTGCTTCCTCCCGGAGTCTTTATGCCCATAGCAGAGGAAACTGGGCAAATTCTGCAAATTGGTGAT
TGGATTATTGAGCAAGCGTGTTTTCAATACGCTCAGTGGAAAAAAGAACAAGTTTTGCCAGAAACGTTCCATCGACTTGC
CATCAACATCAGCCCATTGCAGTTCTCTAAAAATGCCTTTGTCGAACACATCACTCATGCATTGAAACAAGCCAATATCA
CGGGTGAGCATATTGAATTGGAGATCACTGAGAGCTTGCTATTGGAAAACGTCGAAAGCGCGATCAATAAAATGGCAGAG
CTAAAAGAACTGGATCTCAAAATCTCGATCGATGACTTTGGCACCGGTTATTCCTCACTCCGCTATCTCAAACATCTAGC
GGTGGACGTACTGAAAATTGACCGCTCCTTTGTCACTCAGTTGCATCTTGATCAAAGCGACCAAGCCATTGTTTCAACGA
TCATTATGATTGCTGAGCGCTTAAGTTTAGAAGTCATTGCCGAAGGGGTAGAAACAGAAGAAGAGTTCAACACGCTGGTC
GAACTCGGTTGTGAGCAATTTCAGGGATATCTCTTTGGCAAACCACTCCCTGTGGAGATGATCACGCAGAAATTACGTGA
AAGCCGTCAGCACCAAGAGAGTCATTCAAGCAAAGTTAAAAGCAACCAAATAAGTAACTCATAA

Upstream 100 bases:

>100_bases
AACTTAGAGAAACAGCACTGATTCTTAATTTCAGGTTGAGAATTAACCAAACGGTAAATATCGTCTATAACTAAAAGAGT
AATTCACTGCGGTCATCAGT

Downstream 100 bases:

>100_bases
TGATCGCGTCTTCCTTCCCTGACTGAGTAGGATAGTAATTACGGCGACGATCCACTTCGTTAAAACCCATCTCTTGATAG
AGATGAATGGCGTTCACATT

Product: c-di-GMP phosphodiesterase A-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 687; Mature: 687

Protein sequence:

>687_residues
MLRNKKVHSLAFKQARTVFLVSVVLGLCFSLYHILADLHQEQRRIEEHYQFKLLQNYSNASQAAYHLNHLLAEQVASTLM
MDNAIYRVKIVDDFGDVLTQKHREIDSQSLTTQLLSKILTPAQPFYKTELHQPNANAIVGELSFSVDGSSIADAFIKKST
RIVLFDLFRNILLTSILLFFFYFKLSKPIITLINWVNSLQNRKNALELPPGNNNDELGRLALSFHNLWQARAAAESQLNQ
LAYFDTLTGLANRSLLLKSLNETLKESQSEQYPGVLFYLDLDRFKTINDSLGHTIGDNLMRTIAKRLEAWLQPGEIAARI
GGDEFAILIPKLNKEDAANKAKQLLTLISNPYSIDDHQLYCTVSIGISTFADKGISSIDVLRQADTALYRAKVAGRNKYM
FYEPEMQAQVESFLEIEKGLHEALHKGQLELYYQPQVNAQQQIIGVEALIRWNHPEKGVLPPGVFMPIAEETGQILQIGD
WIIEQACFQYAQWKKEQVLPETFHRLAINISPLQFSKNAFVEHITHALKQANITGEHIELEITESLLLENVESAINKMAE
LKELDLKISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVTQLHLDQSDQAIVSTIIMIAERLSLEVIAEGVETEEEFNTLV
ELGCEQFQGYLFGKPLPVEMITQKLRESRQHQESHSSKVKSNQISNS

Sequences:

>Translated_687_residues
MLRNKKVHSLAFKQARTVFLVSVVLGLCFSLYHILADLHQEQRRIEEHYQFKLLQNYSNASQAAYHLNHLLAEQVASTLM
MDNAIYRVKIVDDFGDVLTQKHREIDSQSLTTQLLSKILTPAQPFYKTELHQPNANAIVGELSFSVDGSSIADAFIKKST
RIVLFDLFRNILLTSILLFFFYFKLSKPIITLINWVNSLQNRKNALELPPGNNNDELGRLALSFHNLWQARAAAESQLNQ
LAYFDTLTGLANRSLLLKSLNETLKESQSEQYPGVLFYLDLDRFKTINDSLGHTIGDNLMRTIAKRLEAWLQPGEIAARI
GGDEFAILIPKLNKEDAANKAKQLLTLISNPYSIDDHQLYCTVSIGISTFADKGISSIDVLRQADTALYRAKVAGRNKYM
FYEPEMQAQVESFLEIEKGLHEALHKGQLELYYQPQVNAQQQIIGVEALIRWNHPEKGVLPPGVFMPIAEETGQILQIGD
WIIEQACFQYAQWKKEQVLPETFHRLAINISPLQFSKNAFVEHITHALKQANITGEHIELEITESLLLENVESAINKMAE
LKELDLKISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVTQLHLDQSDQAIVSTIIMIAERLSLEVIAEGVETEEEFNTLV
ELGCEQFQGYLFGKPLPVEMITQKLRESRQHQESHSSKVKSNQISNS
>Mature_687_residues
MLRNKKVHSLAFKQARTVFLVSVVLGLCFSLYHILADLHQEQRRIEEHYQFKLLQNYSNASQAAYHLNHLLAEQVASTLM
MDNAIYRVKIVDDFGDVLTQKHREIDSQSLTTQLLSKILTPAQPFYKTELHQPNANAIVGELSFSVDGSSIADAFIKKST
RIVLFDLFRNILLTSILLFFFYFKLSKPIITLINWVNSLQNRKNALELPPGNNNDELGRLALSFHNLWQARAAAESQLNQ
LAYFDTLTGLANRSLLLKSLNETLKESQSEQYPGVLFYLDLDRFKTINDSLGHTIGDNLMRTIAKRLEAWLQPGEIAARI
GGDEFAILIPKLNKEDAANKAKQLLTLISNPYSIDDHQLYCTVSIGISTFADKGISSIDVLRQADTALYRAKVAGRNKYM
FYEPEMQAQVESFLEIEKGLHEALHKGQLELYYQPQVNAQQQIIGVEALIRWNHPEKGVLPPGVFMPIAEETGQILQIGD
WIIEQACFQYAQWKKEQVLPETFHRLAINISPLQFSKNAFVEHITHALKQANITGEHIELEITESLLLENVESAINKMAE
LKELDLKISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVTQLHLDQSDQAIVSTIIMIAERLSLEVIAEGVETEEEFNTLV
ELGCEQFQGYLFGKPLPVEMITQKLRESRQHQESHSSKVKSNQISNS

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=35.6132075471698, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI87081921, Length=430, Percent_Identity=34.4186046511628, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI226510982, Length=531, Percent_Identity=27.4952919020716, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI87081980, Length=269, Percent_Identity=34.2007434944238, Blast_Score=155, Evalue=9e-39,
Organism=Escherichia coli, GI1790496, Length=258, Percent_Identity=34.1085271317829, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787055, Length=262, Percent_Identity=33.587786259542, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI87081845, Length=241, Percent_Identity=34.8547717842324, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=33.8645418326693, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788849, Length=434, Percent_Identity=27.1889400921659, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1786507, Length=236, Percent_Identity=32.6271186440678, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1788381, Length=452, Percent_Identity=25.4424778761062, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI87082096, Length=239, Percent_Identity=30.5439330543933, Blast_Score=117, Evalue=4e-27,
Organism=Escherichia coli, GI87081743, Length=253, Percent_Identity=32.4110671936759, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=34.7560975609756, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=30.9090909090909, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788956, Length=187, Percent_Identity=36.8983957219251, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1787802, Length=178, Percent_Identity=34.2696629213483, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1789650, Length=470, Percent_Identity=22.1276595744681, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87082007, Length=172, Percent_Identity=33.1395348837209, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI87081881, Length=172, Percent_Identity=34.8837209302326, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87081977, Length=169, Percent_Identity=33.1360946745562, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=27.4390243902439, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787410, Length=150, Percent_Identity=31.3333333333333, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788085, Length=182, Percent_Identity=31.8681318681319, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693134, Length=165, Percent_Identity=27.2727272727273, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 78027; Mature: 78027

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRNKKVHSLAFKQARTVFLVSVVLGLCFSLYHILADLHQEQRRIEEHYQFKLLQNYSNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SQAAYHLNHLLAEQVASTLMMDNAIYRVKIVDDFGDVLTQKHREIDSQSLTTQLLSKILT
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
PAQPFYKTELHQPNANAIVGELSFSVDGSSIADAFIKKSTRIVLFDLFRNILLTSILLFF
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FYFKLSKPIITLINWVNSLQNRKNALELPPGNNNDELGRLALSFHNLWQARAAAESQLNQ
HHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAYFDTLTGLANRSLLLKSLNETLKESQSEQYPGVLFYLDLDRFKTINDSLGHTIGDNLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHHHH
RTIAKRLEAWLQPGEIAARIGGDEFAILIPKLNKEDAANKAKQLLTLISNPYSIDDHQLY
HHHHHHHHHHCCCCHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
CTVSIGISTFADKGISSIDVLRQADTALYRAKVAGRNKYMFYEPEMQAQVESFLEIEKGL
EEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
HEALHKGQLELYYQPQVNAQQQIIGVEALIRWNHPEKGVLPPGVFMPIAEETGQILQIGD
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHCCCCHHHHHH
WIIEQACFQYAQWKKEQVLPETFHRLAINISPLQFSKNAFVEHITHALKQANITGEHIEL
HHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
EITESLLLENVESAINKMAELKELDLKISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVTQ
EEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHLDQSDQAIVSTIIMIAERLSLEVIAEGVETEEEFNTLVELGCEQFQGYLFGKPLPVEM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCEECCCCCCHHH
ITQKLRESRQHQESHSSKVKSNQISNS
HHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRNKKVHSLAFKQARTVFLVSVVLGLCFSLYHILADLHQEQRRIEEHYQFKLLQNYSNA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SQAAYHLNHLLAEQVASTLMMDNAIYRVKIVDDFGDVLTQKHREIDSQSLTTQLLSKILT
HHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
PAQPFYKTELHQPNANAIVGELSFSVDGSSIADAFIKKSTRIVLFDLFRNILLTSILLFF
CCCCHHHHHCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
FYFKLSKPIITLINWVNSLQNRKNALELPPGNNNDELGRLALSFHNLWQARAAAESQLNQ
HHHHHCCHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAYFDTLTGLANRSLLLKSLNETLKESQSEQYPGVLFYLDLDRFKTINDSLGHTIGDNLM
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHCHHHHHHHH
RTIAKRLEAWLQPGEIAARIGGDEFAILIPKLNKEDAANKAKQLLTLISNPYSIDDHQLY
HHHHHHHHHHCCCCHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
CTVSIGISTFADKGISSIDVLRQADTALYRAKVAGRNKYMFYEPEMQAQVESFLEIEKGL
EEEEECHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHH
HEALHKGQLELYYQPQVNAQQQIIGVEALIRWNHPEKGVLPPGVFMPIAEETGQILQIGD
HHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEECCHHCCCCHHHHHH
WIIEQACFQYAQWKKEQVLPETFHRLAINISPLQFSKNAFVEHITHALKQANITGEHIEL
HHHHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
EITESLLLENVESAINKMAELKELDLKISIDDFGTGYSSLRYLKHLAVDVLKIDRSFVTQ
EEHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LHLDQSDQAIVSTIIMIAERLSLEVIAEGVETEEEFNTLVELGCEQFQGYLFGKPLPVEM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHCCEECCCCCCHHH
ITQKLRESRQHQESHSSKVKSNQISNS
HHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]