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The map label for this gene is yciR [C]

Identifier: 37680874

GI number: 37680874

Start: 2728453

End: 2730492

Strand: Direct

Name: yciR [C]

Synonym: VV2690

Alternate gene names: 37680874

Gene position: 2728453-2730492 (Clockwise)

Preceding gene: 37680869

Following gene: 37680875

Centisome position: 81.34

GC content: 46.81

Gene sequence:

>2040_bases
ATGCCTTCCAAGCAAATGCACCATTGGTTTAATAAACTGACTTCTAATAGCCCTTTTTTCTTCGCTATTCTTGATAAGCA
ACATAACTATTGCTTGGTGAATGAACGTTATTGCGACGTTGCGGGGTTAGCTCAGGAAGAGCTAATAGGGATGAATGATG
CACAAATTTTAGGTGACAACTTTTACCAAAAGCTAAAGCCTTACTACGACCGAGCTCTGCTCGGTGAAAGTATTGAGGCC
GAAATCACCCTCGATGAAACCGATCTTGAAACCAGTTTGCATTTTAGTTTGTCCCCTGTGGAAGGTGGAGAACAGATTTC
TCACCTCCTTTTTCAAGCGATTGATACCTCTGAAAAACACATTCTCGTCAAATCCCTAGAAGAGTCAGAAACCAAGTTTT
CTCGTTTAACGCAACTACTGCCCGATGGTTTACTGCTGGTGGAAGAAGACACCATTCTCTCAGCAAACCCCGCTGCGGCT
AGGCTGCTTGGTTTCAATTCGCAGCATGACTTGCTTGGTGAAGAGCTCAGTCGATTATTTATGGATGAGAAGAGCAAGAT
GGTGTTTAGCCATAAACTCTGCTCACTGCTTTCCGAAAAAGCGTTTGTCTGTATGACCAGTGCACGTTGTGGCTTTGAGC
GCCGCGTTCAGTTGCATGCAGATTTCACCACCGTACTGGGCAACCAATCTCAAATCATCTTGATCCAAGACGCTGATGAA
ACGCCCAAACATCTTTCGGTGAAAAACAGCGATGATATTCATATCGATTCCCTGACGAAGCTCTACAACCGCTTCGGTTT
TACCAAACGTCTGGAGCAGTTGATTAAGAGCCAAACCCCCTTGTTGTTGTTTTATCTCGATATCGATAACTTCAAAAACA
TCAATGACTCACTAGGCCACCACATTGGTGACAAAGTGATTCTTGAAGTGGCAGCTCGTCTGAAACGACTGTTGCCACAA
CACTCGGTGATTGGTCATCTCGGGGGCGATGAGTTTGGCGTCATCTTGCCTGAGCCGGAAAACAACCGCATGGCCGAGTT
GCTCTCTGAGCGCATCATCTCCCTAATTAATCAGCCATTTGATTTACACCATTTCAGCAAGCGCCTTGCCTGTTCTATCG
GCAGTGTTCGTTATCCTGAAGATGGCCAAGATGCACGTGTGCTGCTGCAAAATGCCGATACCGCGATGTACGAAGCCAAA
GATCGCGGCCGTAACCGTCTCATTAAGTTTAATGACCAGATGAACAAAGAAGCGCGTATGCGCCTTTGGTTGGAGATCGA
ACTGCAAAAAGCGCTACAGCAAAATGGCCTTGAAGTGTGGTATCAGCCGAAAGTTAATGCGCGTGACTTCAGCATTAATG
GCGCCGAAGCATTAGTACGCTGGAAGCACCCTGTCGAAGGATACATTAGCCCTGCTGCGTTCATTCCTGTCGCTGAAAAA
GCAGGTCTGATTGAGCACTTAGGTCGTGTGGTCATGCGGGATGTATTCAACACGGTCAAACGCTGGAAACTCCAAGGAAT
TCTGCCTGGTCGCGTTGCGATTAACTTATCGCCAGAGCAATTTGGCAACCCTCAGTTGATCGACTTTATGGAAAAGCTCC
TGAGAACCACGGAGTTAGACCCTAACTGCATCACTTTCGAGCTGACTGAAAGTGCGGTAATGAGTGACAGTGACCACACT
ATTCAGATGCTCAACGCGATTAAGAAACTGGGCTTCTCACTCTCCATCGATGACTTTGGTACCGGTTATTCCTCACTGGC
GTATTTAGCCCGCTTCCCGATTGATGAACTGAAGATCGACCGCGCGTTTATCAATGACATTGACGTTTTACCGAAGCAGG
TCACGGTGATTGAAAACATCATTAATCTCGGCAAATCTCTCAATCTCACCGTGGTGGCCGAAGGGGTAGAAACTCATCAG
CAAGCGGCACTCCTGTCGAATTTGCGCTGTCACTCGATCCAGGGGTTCCATTTCCATCGCCCTCAGCCTAAACATGAGAT
AGAAGAACTGTTTGCACAAAATCGTCGCCATAAAAACTGA

Upstream 100 bases:

>100_bases
AGCCTTTAATAACGCTATTATCACAGTTATAGTGATTGCGTTTCAGCGATTTCATGACATGGACGATTAATTACGCTCTC
TGGAGACGGGTAGTACTTTG

Downstream 100 bases:

>100_bases
CCATCTCCCCTCTCCAAAAGAGGTAAATCTCAATTTATTGCGTCAAACCTAACTTACATCAATTCTGCTATTCATATTCC
TTCATAAAATGCCCACACCC

Product: c-di-GMP phosphodiesterase A-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 678

Protein sequence:

>679_residues
MPSKQMHHWFNKLTSNSPFFFAILDKQHNYCLVNERYCDVAGLAQEELIGMNDAQILGDNFYQKLKPYYDRALLGESIEA
EITLDETDLETSLHFSLSPVEGGEQISHLLFQAIDTSEKHILVKSLEESETKFSRLTQLLPDGLLLVEEDTILSANPAAA
RLLGFNSQHDLLGEELSRLFMDEKSKMVFSHKLCSLLSEKAFVCMTSARCGFERRVQLHADFTTVLGNQSQIILIQDADE
TPKHLSVKNSDDIHIDSLTKLYNRFGFTKRLEQLIKSQTPLLLFYLDIDNFKNINDSLGHHIGDKVILEVAARLKRLLPQ
HSVIGHLGGDEFGVILPEPENNRMAELLSERIISLINQPFDLHHFSKRLACSIGSVRYPEDGQDARVLLQNADTAMYEAK
DRGRNRLIKFNDQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFSINGAEALVRWKHPVEGYISPAAFIPVAEK
AGLIEHLGRVVMRDVFNTVKRWKLQGILPGRVAINLSPEQFGNPQLIDFMEKLLRTTELDPNCITFELTESAVMSDSDHT
IQMLNAIKKLGFSLSIDDFGTGYSSLAYLARFPIDELKIDRAFINDIDVLPKQVTVIENIINLGKSLNLTVVAEGVETHQ
QAALLSNLRCHSIQGFHFHRPQPKHEIEELFAQNRRHKN

Sequences:

>Translated_679_residues
MPSKQMHHWFNKLTSNSPFFFAILDKQHNYCLVNERYCDVAGLAQEELIGMNDAQILGDNFYQKLKPYYDRALLGESIEA
EITLDETDLETSLHFSLSPVEGGEQISHLLFQAIDTSEKHILVKSLEESETKFSRLTQLLPDGLLLVEEDTILSANPAAA
RLLGFNSQHDLLGEELSRLFMDEKSKMVFSHKLCSLLSEKAFVCMTSARCGFERRVQLHADFTTVLGNQSQIILIQDADE
TPKHLSVKNSDDIHIDSLTKLYNRFGFTKRLEQLIKSQTPLLLFYLDIDNFKNINDSLGHHIGDKVILEVAARLKRLLPQ
HSVIGHLGGDEFGVILPEPENNRMAELLSERIISLINQPFDLHHFSKRLACSIGSVRYPEDGQDARVLLQNADTAMYEAK
DRGRNRLIKFNDQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFSINGAEALVRWKHPVEGYISPAAFIPVAEK
AGLIEHLGRVVMRDVFNTVKRWKLQGILPGRVAINLSPEQFGNPQLIDFMEKLLRTTELDPNCITFELTESAVMSDSDHT
IQMLNAIKKLGFSLSIDDFGTGYSSLAYLARFPIDELKIDRAFINDIDVLPKQVTVIENIINLGKSLNLTVVAEGVETHQ
QAALLSNLRCHSIQGFHFHRPQPKHEIEELFAQNRRHKN
>Mature_678_residues
PSKQMHHWFNKLTSNSPFFFAILDKQHNYCLVNERYCDVAGLAQEELIGMNDAQILGDNFYQKLKPYYDRALLGESIEAE
ITLDETDLETSLHFSLSPVEGGEQISHLLFQAIDTSEKHILVKSLEESETKFSRLTQLLPDGLLLVEEDTILSANPAAAR
LLGFNSQHDLLGEELSRLFMDEKSKMVFSHKLCSLLSEKAFVCMTSARCGFERRVQLHADFTTVLGNQSQIILIQDADET
PKHLSVKNSDDIHIDSLTKLYNRFGFTKRLEQLIKSQTPLLLFYLDIDNFKNINDSLGHHIGDKVILEVAARLKRLLPQH
SVIGHLGGDEFGVILPEPENNRMAELLSERIISLINQPFDLHHFSKRLACSIGSVRYPEDGQDARVLLQNADTAMYEAKD
RGRNRLIKFNDQMNKEARMRLWLEIELQKALQQNGLEVWYQPKVNARDFSINGAEALVRWKHPVEGYISPAAFIPVAEKA
GLIEHLGRVVMRDVFNTVKRWKLQGILPGRVAINLSPEQFGNPQLIDFMEKLLRTTELDPNCITFELTESAVMSDSDHTI
QMLNAIKKLGFSLSIDDFGTGYSSLAYLARFPIDELKIDRAFINDIDVLPKQVTVIENIINLGKSLNLTVVAEGVETHQQ
AALLSNLRCHSIQGFHFHRPQPKHEIEELFAQNRRHKN

Specific function: Unknown

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=510, Percent_Identity=32.7450980392157, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI87081921, Length=415, Percent_Identity=32.0481927710843, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI226510982, Length=437, Percent_Identity=27.2311212814645, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI87081845, Length=241, Percent_Identity=35.6846473029046, Blast_Score=153, Evalue=4e-38,
Organism=Escherichia coli, GI1788502, Length=243, Percent_Identity=36.6255144032922, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=35.4430379746835, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI87081743, Length=240, Percent_Identity=34.1666666666667, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1787055, Length=315, Percent_Identity=28.2539682539683, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI87081980, Length=252, Percent_Identity=34.5238095238095, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1786507, Length=238, Percent_Identity=32.7731092436975, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI87082096, Length=417, Percent_Identity=24.220623501199, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788381, Length=195, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=31.3807531380753, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1787262, Length=160, Percent_Identity=33.125, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788956, Length=184, Percent_Identity=33.1521739130435, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787802, Length=157, Percent_Identity=35.031847133758, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=37.1069182389937, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=32.9268292682927, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI87081977, Length=152, Percent_Identity=36.8421052631579, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1787410, Length=152, Percent_Identity=30.9210526315789, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081881, Length=276, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788085, Length=158, Percent_Identity=28.4810126582279, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=31.7073170731707, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=32.3170731707317, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787056, Length=175, Percent_Identity=33.1428571428571, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081974, Length=101, Percent_Identity=37.6237623762376, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 77286; Mature: 77155

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKQMHHWFNKLTSNSPFFFAILDKQHNYCLVNERYCDVAGLAQEELIGMNDAQILGDN
CCCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCHHCCCHHHHCCCCCHHHHHHH
FYQKLKPYYDRALLGESIEAEITLDETDLETSLHFSLSPVEGGEQISHLLFQAIDTSEKH
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCE
ILVKSLEESETKFSRLTQLLPDGLLLVEEDTILSANPAAARLLGFNSQHDLLGEELSRLF
EHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHCCCCCHHHHHHHHHHHH
MDEKSKMVFSHKLCSLLSEKAFVCMTSARCGFERRVQLHADFTTVLGNQSQIILIQDADE
HCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHEEEEEECHHHHHCCCCEEEEEECCCC
TPKHLSVKNSDDIHIDSLTKLYNRFGFTKRLEQLIKSQTPLLLFYLDIDNFKNINDSLGH
CCCCEECCCCCCEEHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
HIGDKVILEVAARLKRLLPQHSVIGHLGGDEFGVILPEPENNRMAELLSERIISLINQPF
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DLHHFSKRLACSIGSVRYPEDGQDARVLLQNADTAMYEAKDRGRNRLIKFNDQMNKEARM
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCE
RLWLEIELQKALQQNGLEVWYQPKVNARDFSINGAEALVRWKHPVEGYISPAAFIPVAEK
EEEEEHHHHHHHHHCCCEEEECCCCCCCEECCCCHHHHEEECCCCCCCCCCHHCCCCHHH
AGLIEHLGRVVMRDVFNTVKRWKLQGILPGRVAINLSPEQFGNPQLIDFMEKLLRTTELD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHHHCCCC
PNCITFELTESAVMSDSDHTIQMLNAIKKLGFSLSIDDFGTGYSSLAYLARFPIDELKID
CCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHH
RAFINDIDVLPKQVTVIENIINLGKSLNLTVVAEGVETHQQAALLSNLRCHSIQGFHFHR
HHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC
PQPKHEIEELFAQNRRHKN
CCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PSKQMHHWFNKLTSNSPFFFAILDKQHNYCLVNERYCDVAGLAQEELIGMNDAQILGDN
CCHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCCHHCCCHHHHCCCCCHHHHHHH
FYQKLKPYYDRALLGESIEAEITLDETDLETSLHFSLSPVEGGEQISHLLFQAIDTSEKH
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCE
ILVKSLEESETKFSRLTQLLPDGLLLVEEDTILSANPAAARLLGFNSQHDLLGEELSRLF
EHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEECCCCHHHHHHCCCCCHHHHHHHHHHHH
MDEKSKMVFSHKLCSLLSEKAFVCMTSARCGFERRVQLHADFTTVLGNQSQIILIQDADE
HCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHEEEEEECHHHHHCCCCEEEEEECCCC
TPKHLSVKNSDDIHIDSLTKLYNRFGFTKRLEQLIKSQTPLLLFYLDIDNFKNINDSLGH
CCCCEECCCCCCEEHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHH
HIGDKVILEVAARLKRLLPQHSVIGHLGGDEFGVILPEPENNRMAELLSERIISLINQPF
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCC
DLHHFSKRLACSIGSVRYPEDGQDARVLLQNADTAMYEAKDRGRNRLIKFNDQMNKEARM
CHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEECCCCCCCCCE
RLWLEIELQKALQQNGLEVWYQPKVNARDFSINGAEALVRWKHPVEGYISPAAFIPVAEK
EEEEEHHHHHHHHHCCCEEEECCCCCCCEECCCCHHHHEEECCCCCCCCCCHHCCCCHHH
AGLIEHLGRVVMRDVFNTVKRWKLQGILPGRVAINLSPEQFGNPQLIDFMEKLLRTTELD
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECHHHCCCCHHHHHHHHHHHHCCCC
PNCITFELTESAVMSDSDHTIQMLNAIKKLGFSLSIDDFGTGYSSLAYLARFPIDELKID
CCEEEEEECCHHHCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHCCHHHHHHH
RAFINDIDVLPKQVTVIENIINLGKSLNLTVVAEGVETHQQAALLSNLRCHSIQGFHFHR
HHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCC
PQPKHEIEELFAQNRRHKN
CCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]