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The map label for this gene is fadE

Identifier: 37680703

GI number: 37680703

Start: 2549078

End: 2551525

Strand: Direct

Name: fadE

Synonym: VV2519

Alternate gene names: 37680703

Gene position: 2549078-2551525 (Clockwise)

Preceding gene: 161486611

Following gene: 37680705

Centisome position: 75.99

GC content: 49.88

Gene sequence:

>2448_bases
ATGGACATCTTGCTCTCCCTACTCGCGATGACCTTGATATTGGGCGTGACGCTCTATCATCGAATGTCATTAGTCAAATC
CGTCACCTTGTTGACCGCCACGATGCTGCTGTTAACTTTCTCCGGTTACGTCGGCTCAATCGGCTGGCTAAGCTACTTCT
TAGCGCTGGCGGTATTCGCTATGCCCTCTGTACGCCAATCGCTCATCAGTGCAAAAGCGCTCGGCTTGTTTAAGCAAGTG
CTTCCAGCCATGTCTCAGACAGAAAAAGAAGCGTTGGATGCAGGTACCGTTTGGTGGGAAGCGGAGCTTTTCAAAGGCAA
GCCAGAATGGAAAAAGCTACACGCCATTCCAGCACCAAAACTCTCTGCTGAAGAGCAAGCCTTCCTCGATGGTCCGGTAA
ATGAAGTGTGTGCCATGGTAAGCGATTACCAAGTGACGCATGAACTGGCCGATCTGCCTCCTGAAGTTTGGCAGTATCTC
AAAGATCACAAATTCTTCGCCATGATCATTAAGAAGAAATACGGTGGCCTTGAGTTTTCTGCTTACGCGCAATCTTTGGT
ACTGCAAAAACTGACTGGTGTCTCTGGTGTTCTTTCTTCGACCGTTGGCGTACCAAACTCTTTGGGTCCTGGTGAGCTTT
TGCAACATTACGGTACAGAAGAGCAGAAAAATTACTATCTTCCTCGCCTTGCAGAAGGTAAAGAGATCCCCTGTTTTGCC
CTCACCAGCCCTGAAGCGGGTTCGGATGCGGGTTCTATTCCAGATGACGGTGTGGTCTGTAAAGGCGAATGGGAAGGCAA
AGAAGTCTTGGGCATGCGCCTAACATGGAACAAGCGCTACATTACCCTTGCCCCTGTAGCAACGGTTTTGGGCCTTGCTT
TCAAACTTCGCGATCCTGAAGGCTTACTCGGCGAGCAAGAAGATCTTGGTATTACTTGTGCGCTTATCCCAACAGACATT
AAAGGGGTTGAAATCGGCAACCGTCATTTCCCTCTCAATGTCCCCTTCCAGAATGGCCCAACGCGTGGCCAAGATATTTT
CGTTCCGATCGATTTCATTATCGGTGGCCAAAAAATGGCAGGCCAAGGCTGGCGCATGCTGGTTGAATGTCTCTCTGTTG
GTCGCGGTATTACCCTGCCTTCAAACTCAACCGGTGGTATCAAATCCGCTGCATTGGCAACCGGTGCTTACTCGCGCATT
CGTCGCCAGTTTAAACAGCCTATCGGCCATCTTGAAGGTGTAGAAGAAGCGTTGGCACGCTTAGGTGGTAACGCGTATGT
GATGGACGCAGCAAGCAATCTTACCGTTGCCGGTATCGATCTTGGTGAGAAACCATCGGTCATCTCCGCGATTGTGAAAT
ACCATTGTACTCACCGTGGCCAACGCAGCATCATCGATGCAATGGATATCGTTGGTGGTAAAGGCATTTGCCTTGGTCCC
TCCAACTTCCTTGCTCGTGGCTACCAAGGTTCACCCATCGCCGTCACGGTGGAAGGGGCAAACATCCTCACTCGTTCAAT
GATCATCTATGGTCAAGGCGCAATTCGTTGCCATCCCTATGTACTAAAAGAGATGGAAGCCGCCTACTCGGACAAATCTG
ATGCGGTAGAACAGTTCGATGCAGCCTTGGCTGGCCACGTCAGCTTTACCATGAGCAACCTTGTGCGCAGCATTTGGTTT
GGTTTGACCGATGGTTTTGGCTCGAACGCCCCAACGCACGACGCCACCAAACGTTACTACCAGAAGCTCAATCGCTATAG
CGCCAACATGGCATTATTGTCAGACATTTCAATGGCCGTGCTGGGTGGCTCATTGAAGCGTCGTGAGCGTCTATCAGCCC
GCTTAGGCGATATCCTCAGTCAGCTTTACTTGAGCTCAGCGACCTTAAAACGCTTTGAACAAGATGGCCGCCCTGTCGAA
GACCTGCCTTTGGTTCACTGGGGTTTGCAAGACAGCTTGAAGCAAACAGAAGTGGCCATTGATGAGTTTCTTGCCAACTT
CCCGAACCCCATCATTGGTAAAGCATTGCGCGTCTTGATCATGCCATTTGGCCGTGTGCGCAAAGCACCAAGCGACAAAA
TCGATAGTCAAGTTGCACGCATACTACAAACCCCAAGCGCGACACGTAGCCGCATTGGTCGCAATCAGTATTTGCAACCA
ACAGAGCACAACGCAGCAGGCAAGATTGAGCTAGCACTGTCTGTGATTTTGCAAGCAGAACCTGTGTTTGACAAAGTGTG
TAAAGCACAAGGTAAACGCCGCCCATTCTTACGTTTGGATGCCATTGCAGAAGAGGGGCTAGCACAAGGCATTATTTCTC
AAGATGAAGCCGATTTGCTTAAAGAAGCGGAGCAACATCGTTTGTACACCATCAATGTTGATGACTTTGAGCCAGAACAT
CTGGCGGCAAAAAAGTCTCATACCGATGTGATGGATAACGTTGCTTAG

Upstream 100 bases:

>100_bases
CATTTCTTTAATATTTTGATTACACTTAAATCAACTGGTTTGACCTCTTACCAAAACACAGACGTATAACACAACGAATT
GTCTGAAAAGGAACCTACAT

Downstream 100 bases:

>100_bases
TCACCACAAAAGTATCACAAGTACAACGGGAGCCGAGCTCCCGTTTTTTTATGTATAAAGACTCTCACCGCCTTTCAATA
AATCTTTTGTTCAGCGGCAA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 815

Protein sequence:

>815_residues
MDILLSLLAMTLILGVTLYHRMSLVKSVTLLTATMLLLTFSGYVGSIGWLSYFLALAVFAMPSVRQSLISAKALGLFKQV
LPAMSQTEKEALDAGTVWWEAELFKGKPEWKKLHAIPAPKLSAEEQAFLDGPVNEVCAMVSDYQVTHELADLPPEVWQYL
KDHKFFAMIIKKKYGGLEFSAYAQSLVLQKLTGVSGVLSSTVGVPNSLGPGELLQHYGTEEQKNYYLPRLAEGKEIPCFA
LTSPEAGSDAGSIPDDGVVCKGEWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPEGLLGEQEDLGITCALIPTDI
KGVEIGNRHFPLNVPFQNGPTRGQDIFVPIDFIIGGQKMAGQGWRMLVECLSVGRGITLPSNSTGGIKSAALATGAYSRI
RRQFKQPIGHLEGVEEALARLGGNAYVMDAASNLTVAGIDLGEKPSVISAIVKYHCTHRGQRSIIDAMDIVGGKGICLGP
SNFLARGYQGSPIAVTVEGANILTRSMIIYGQGAIRCHPYVLKEMEAAYSDKSDAVEQFDAALAGHVSFTMSNLVRSIWF
GLTDGFGSNAPTHDATKRYYQKLNRYSANMALLSDISMAVLGGSLKRRERLSARLGDILSQLYLSSATLKRFEQDGRPVE
DLPLVHWGLQDSLKQTEVAIDEFLANFPNPIIGKALRVLIMPFGRVRKAPSDKIDSQVARILQTPSATRSRIGRNQYLQP
TEHNAAGKIELALSVILQAEPVFDKVCKAQGKRRPFLRLDAIAEEGLAQGIISQDEADLLKEAEQHRLYTINVDDFEPEH
LAAKKSHTDVMDNVA

Sequences:

>Translated_815_residues
MDILLSLLAMTLILGVTLYHRMSLVKSVTLLTATMLLLTFSGYVGSIGWLSYFLALAVFAMPSVRQSLISAKALGLFKQV
LPAMSQTEKEALDAGTVWWEAELFKGKPEWKKLHAIPAPKLSAEEQAFLDGPVNEVCAMVSDYQVTHELADLPPEVWQYL
KDHKFFAMIIKKKYGGLEFSAYAQSLVLQKLTGVSGVLSSTVGVPNSLGPGELLQHYGTEEQKNYYLPRLAEGKEIPCFA
LTSPEAGSDAGSIPDDGVVCKGEWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPEGLLGEQEDLGITCALIPTDI
KGVEIGNRHFPLNVPFQNGPTRGQDIFVPIDFIIGGQKMAGQGWRMLVECLSVGRGITLPSNSTGGIKSAALATGAYSRI
RRQFKQPIGHLEGVEEALARLGGNAYVMDAASNLTVAGIDLGEKPSVISAIVKYHCTHRGQRSIIDAMDIVGGKGICLGP
SNFLARGYQGSPIAVTVEGANILTRSMIIYGQGAIRCHPYVLKEMEAAYSDKSDAVEQFDAALAGHVSFTMSNLVRSIWF
GLTDGFGSNAPTHDATKRYYQKLNRYSANMALLSDISMAVLGGSLKRRERLSARLGDILSQLYLSSATLKRFEQDGRPVE
DLPLVHWGLQDSLKQTEVAIDEFLANFPNPIIGKALRVLIMPFGRVRKAPSDKIDSQVARILQTPSATRSRIGRNQYLQP
TEHNAAGKIELALSVILQAEPVFDKVCKAQGKRRPFLRLDAIAEEGLAQGIISQDEADLLKEAEQHRLYTINVDDFEPEH
LAAKKSHTDVMDNVA
>Mature_815_residues
MDILLSLLAMTLILGVTLYHRMSLVKSVTLLTATMLLLTFSGYVGSIGWLSYFLALAVFAMPSVRQSLISAKALGLFKQV
LPAMSQTEKEALDAGTVWWEAELFKGKPEWKKLHAIPAPKLSAEEQAFLDGPVNEVCAMVSDYQVTHELADLPPEVWQYL
KDHKFFAMIIKKKYGGLEFSAYAQSLVLQKLTGVSGVLSSTVGVPNSLGPGELLQHYGTEEQKNYYLPRLAEGKEIPCFA
LTSPEAGSDAGSIPDDGVVCKGEWEGKEVLGMRLTWNKRYITLAPVATVLGLAFKLRDPEGLLGEQEDLGITCALIPTDI
KGVEIGNRHFPLNVPFQNGPTRGQDIFVPIDFIIGGQKMAGQGWRMLVECLSVGRGITLPSNSTGGIKSAALATGAYSRI
RRQFKQPIGHLEGVEEALARLGGNAYVMDAASNLTVAGIDLGEKPSVISAIVKYHCTHRGQRSIIDAMDIVGGKGICLGP
SNFLARGYQGSPIAVTVEGANILTRSMIIYGQGAIRCHPYVLKEMEAAYSDKSDAVEQFDAALAGHVSFTMSNLVRSIWF
GLTDGFGSNAPTHDATKRYYQKLNRYSANMALLSDISMAVLGGSLKRRERLSARLGDILSQLYLSSATLKRFEQDGRPVE
DLPLVHWGLQDSLKQTEVAIDEFLANFPNPIIGKALRVLIMPFGRVRKAPSDKIDSQVARILQTPSATRSRIGRNQYLQP
TEHNAAGKIELALSVILQAEPVFDKVCKAQGKRRPFLRLDAIAEEGLAQGIISQDEADLLKEAEQHRLYTINVDDFEPEH
LAAKKSHTDVMDNVA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=547, Percent_Identity=26.1425959780622, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI4557235, Length=439, Percent_Identity=25.0569476082005, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI76496475, Length=418, Percent_Identity=25.3588516746411, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI226958414, Length=268, Percent_Identity=25.7462686567164, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI226958412, Length=268, Percent_Identity=25.7462686567164, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI87081702, Length=808, Percent_Identity=68.3168316831683, Blast_Score=1150, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=357, Percent_Identity=24.0896358543417, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71985184, Length=413, Percent_Identity=23.4866828087167, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=323, Percent_Identity=23.2198142414861, Blast_Score=74, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=356, Percent_Identity=22.752808988764, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=238, Percent_Identity=27.3109243697479, Blast_Score=67, Evalue=4e-11,
Organism=Drosophila melanogaster, GI281363737, Length=375, Percent_Identity=26.9333333333333, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646207, Length=368, Percent_Identity=24.7282608695652, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355753, Length=349, Percent_Identity=22.3495702005731, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19920834, Length=193, Percent_Identity=29.5336787564767, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89016; Mature: 89016

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]