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The map label for this gene is hlyB [H]

Identifier: 37680559

GI number: 37680559

Start: 2404646

End: 2406658

Strand: Direct

Name: hlyB [H]

Synonym: VV2375

Alternate gene names: 37680559

Gene position: 2404646-2406658 (Clockwise)

Preceding gene: 37680551

Following gene: 37680560

Centisome position: 71.68

GC content: 48.34

Gene sequence:

>2013_bases
ATGTGGGAGAGGGCTAAAAGTATGCAAGGCTCAGTCATTAAAAGGATGTATGCCGGCTTCGCGCTGATAATCGTCTTGTT
TGCCGTTACAGTCACCATTATGACCAATGGCATGAATCAAATTCATTCCAACTTCGAAACCGTTTCGAAAAATTCACTGC
CTTTGGTTTCGTTATCCAACCAAACCAGCGTTGAATTGTTATCTGCGGATAAATCTTTTAAAGATTTTCTCACCACGCAG
AACCAAGATCGCATGACGCAGATGCGCAGCGAATTTGGTAAATCGCAAACTGAGTTTAATCAAACGCTCAACGAACTCGA
AAACGCTAGCAAGGCCTACCCTGCACTCGCAGAGCCTTTAGCTCAACTCAGAGAAATTGAAAACAGCTACTTTGCGGAAG
CCAATGAAGCAATGAACAACTATGAAGCGATGTTTGCTGCACAAGCAGAAGTGCAAAAATCATCACGTCGCTTCCAAAAA
CTTCACACCGAACTGACGGTTGGTATGAAAGAGTACGTCGATGACCAATCCAGCATTTCTGTCAAAGTGATGGCAAAAAG
CTATTTCATTAAGTTGAAAGATGCTGAAGTGATCACCTCAGATGCACTGGCCAGCTCAGACCTTGAGTTTGTGAAAAAGG
CAGTGAACAAAAACAAGAAAGCGGTCACTCACCTTAATTACGCTTATCGTGGCCTCACGACCCAACTGCCATCACTGAAA
GATGTGTTCAATGCATCTGTCGAGCAGTTCACTCAGGACGTGGGCCAAAAAGGCGGGGTGTTGGATCAACACGCCAGCTA
CCTTGAAGCCAAAGCTGCTTTGTATGACAACATCGCCAACCTAGCGGTCAAAGTTGACTCTGCGATGCGATTGTTGGAAA
CCTTTACTACAACAGCAACCGACAACCTCAACACCTCTTTGGTTGAAGCAGGCGAAGTGTACGACCAAGGCTTGCTCAAA
GCGATTGTGATTGGCATTGCGGTGACCATTTTTGCCGCCGCTGTGGGCTATCACATTGCCCACAGCGTTCGTGAGCCGTT
AACACGTATTCTTTCCACTTTGGAAGGGCTTGCCAACGGTGATATGACGCAGCGTATCGAAATTCGTTACAACAACGAGT
TCAGTCGAGTGAGTGGCCACATCAATACACTGGCAGATAGCCTGCACGACATTTTGGTGAAACTGAATGATGCGGCGGAA
AATCTGACCGACACCGCAGCAAACAATGAACGCACCTCGAGCAACGCGCAAAACCAACTGAATGCACAACGCGAGCAAAC
CGCCAGCGTAGCCACTGCAATGACCGAAATGAGTCACTCCGTTCAAGAAGTGGCCCAGAGCGCGCAAGGTTCGTTGGAAA
TGGTGCAAAAAGTGGAATCGGCGTCTGAATCTGGCCGTACCATCATGAGTAGCAATATCTCCACCATCAATCAATTGGAA
ACTCGCCTAAACGAATCGGTCAGCGCGGTTTCTGAATTGCAACGCATGAGTGGTCAAATTGGCTCGATTCTCGATGTGAT
TCGCAACATTGCAGAGCAAACCAACCTTCTTGCCCTCAACGCGGCAATTGAAGCTGCGCGTGCGGGCGAGCAGGGCCGCG
GCTTTGCGGTGGTTGCAGACGAAGTTCGAGTACTCGCATCGAAGACCACCCAATCAACCACTGAAATTGAATCGATGATC
AGCAATCTGCAGTCCAGCTCGCAGTCGGCAAGTCATGTGATTCAAAGTTGCATGAGTGATATGGAGATGTCAGTTGAGCA
AGCCTCGAAAGCCAACGGGGCGATGGAAGAGATTCAGGCGTTGATCATCGAAATCAGCCAAATGAGTACGCACATTTCAC
AAGCGGCCGCAGAACAGAGCGAAACGTCAACCTCTATTGCACGTAGCTTGGAAGACATCAATAACATCGCAGACCGTAGT
TACCATGCGATGGCGGAAATCGCAGCCACCAGCGAGAGCCTCTCTAGCTTAGCGAGTCAACAGACTGAATTGGTGCATCG
CTTTAAGCTCTAA

Upstream 100 bases:

>100_bases
TTGCAGCCCTCGCCACAAAATGCTCATCTCAATCTCAATACAATGATGACAATTTTGTTAGTTTTTTGAGACGGGTTCCG
TTTCTTTTTTCTTTTGTTAC

Downstream 100 bases:

>100_bases
ATTTCAACAGAAATCCCCTCAAACGGGGGAAAGTCATCTGGTAAGGGCAACTTTTGACAAAGTTGCCCTTGTTTTTTATG
CGCTGTGTCTACATATGAAG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MWERAKSMQGSVIKRMYAGFALIIVLFAVTVTIMTNGMNQIHSNFETVSKNSLPLVSLSNQTSVELLSADKSFKDFLTTQ
NQDRMTQMRSEFGKSQTEFNQTLNELENASKAYPALAEPLAQLREIENSYFAEANEAMNNYEAMFAAQAEVQKSSRRFQK
LHTELTVGMKEYVDDQSSISVKVMAKSYFIKLKDAEVITSDALASSDLEFVKKAVNKNKKAVTHLNYAYRGLTTQLPSLK
DVFNASVEQFTQDVGQKGGVLDQHASYLEAKAALYDNIANLAVKVDSAMRLLETFTTTATDNLNTSLVEAGEVYDQGLLK
AIVIGIAVTIFAAAVGYHIAHSVREPLTRILSTLEGLANGDMTQRIEIRYNNEFSRVSGHINTLADSLHDILVKLNDAAE
NLTDTAANNERTSSNAQNQLNAQREQTASVATAMTEMSHSVQEVAQSAQGSLEMVQKVESASESGRTIMSSNISTINQLE
TRLNESVSAVSELQRMSGQIGSILDVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLASKTTQSTTEIESMI
SNLQSSSQSASHVIQSCMSDMEMSVEQASKANGAMEEIQALIIEISQMSTHISQAAAEQSETSTSIARSLEDINNIADRS
YHAMAEIAATSESLSSLASQQTELVHRFKL

Sequences:

>Translated_670_residues
MWERAKSMQGSVIKRMYAGFALIIVLFAVTVTIMTNGMNQIHSNFETVSKNSLPLVSLSNQTSVELLSADKSFKDFLTTQ
NQDRMTQMRSEFGKSQTEFNQTLNELENASKAYPALAEPLAQLREIENSYFAEANEAMNNYEAMFAAQAEVQKSSRRFQK
LHTELTVGMKEYVDDQSSISVKVMAKSYFIKLKDAEVITSDALASSDLEFVKKAVNKNKKAVTHLNYAYRGLTTQLPSLK
DVFNASVEQFTQDVGQKGGVLDQHASYLEAKAALYDNIANLAVKVDSAMRLLETFTTTATDNLNTSLVEAGEVYDQGLLK
AIVIGIAVTIFAAAVGYHIAHSVREPLTRILSTLEGLANGDMTQRIEIRYNNEFSRVSGHINTLADSLHDILVKLNDAAE
NLTDTAANNERTSSNAQNQLNAQREQTASVATAMTEMSHSVQEVAQSAQGSLEMVQKVESASESGRTIMSSNISTINQLE
TRLNESVSAVSELQRMSGQIGSILDVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLASKTTQSTTEIESMI
SNLQSSSQSASHVIQSCMSDMEMSVEQASKANGAMEEIQALIIEISQMSTHISQAAAEQSETSTSIARSLEDINNIADRS
YHAMAEIAATSESLSSLASQQTELVHRFKL
>Mature_670_residues
MWERAKSMQGSVIKRMYAGFALIIVLFAVTVTIMTNGMNQIHSNFETVSKNSLPLVSLSNQTSVELLSADKSFKDFLTTQ
NQDRMTQMRSEFGKSQTEFNQTLNELENASKAYPALAEPLAQLREIENSYFAEANEAMNNYEAMFAAQAEVQKSSRRFQK
LHTELTVGMKEYVDDQSSISVKVMAKSYFIKLKDAEVITSDALASSDLEFVKKAVNKNKKAVTHLNYAYRGLTTQLPSLK
DVFNASVEQFTQDVGQKGGVLDQHASYLEAKAALYDNIANLAVKVDSAMRLLETFTTTATDNLNTSLVEAGEVYDQGLLK
AIVIGIAVTIFAAAVGYHIAHSVREPLTRILSTLEGLANGDMTQRIEIRYNNEFSRVSGHINTLADSLHDILVKLNDAAE
NLTDTAANNERTSSNAQNQLNAQREQTASVATAMTEMSHSVQEVAQSAQGSLEMVQKVESASESGRTIMSSNISTINQLE
TRLNESVSAVSELQRMSGQIGSILDVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRVLASKTTQSTTEIESMI
SNLQSSSQSASHVIQSCMSDMEMSVEQASKANGAMEEIQALIIEISQMSTHISQAAAEQSETSTSIARSLEDINNIADRS
YHAMAEIAATSESLSSLASQQTELVHRFKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=30.1675977653631, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI2367378, Length=311, Percent_Identity=28.9389067524116, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1788195, Length=266, Percent_Identity=30.0751879699248, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788194, Length=350, Percent_Identity=26.5714285714286, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=271, Percent_Identity=30.9963099630996, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 73187; Mature: 73187

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWERAKSMQGSVIKRMYAGFALIIVLFAVTVTIMTNGMNQIHSNFETVSKNSLPLVSLSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECC
QTSVELLSADKSFKDFLTTQNQDRMTQMRSEFGKSQTEFNQTLNELENASKAYPALAEPL
CCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AQLREIENSYFAEANEAMNNYEAMFAAQAEVQKSSRRFQKLHTELTVGMKEYVDDQSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VKVMAKSYFIKLKDAEVITSDALASSDLEFVKKAVNKNKKAVTHLNYAYRGLTTQLPSLK
EEEEEHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
DVFNASVEQFTQDVGQKGGVLDQHASYLEAKAALYDNIANLAVKVDSAMRLLETFTTTAT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNLNTSLVEAGEVYDQGLLKAIVIGIAVTIFAAAVGYHIAHSVREPLTRILSTLEGLANG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMTQRIEIRYNNEFSRVSGHINTLADSLHDILVKLNDAAENLTDTAANNERTSSNAQNQL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
NAQREQTASVATAMTEMSHSVQEVAQSAQGSLEMVQKVESASESGRTIMSSNISTINQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEHHCCHHHHHHHH
TRLNESVSAVSELQRMSGQIGSILDVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHH
EVRVLASKTTQSTTEIESMISNLQSSSQSASHVIQSCMSDMEMSVEQASKANGAMEEIQA
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIIEISQMSTHISQAAAEQSETSTSIARSLEDINNIADRSYHAMAEIAATSESLSSLASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTELVHRFKL
HHHHHHHHCC
>Mature Secondary Structure
MWERAKSMQGSVIKRMYAGFALIIVLFAVTVTIMTNGMNQIHSNFETVSKNSLPLVSLSN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEECC
QTSVELLSADKSFKDFLTTQNQDRMTQMRSEFGKSQTEFNQTLNELENASKAYPALAEPL
CCCHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHH
AQLREIENSYFAEANEAMNNYEAMFAAQAEVQKSSRRFQKLHTELTVGMKEYVDDQSSIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
VKVMAKSYFIKLKDAEVITSDALASSDLEFVKKAVNKNKKAVTHLNYAYRGLTTQLPSLK
EEEEEHHHEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHH
DVFNASVEQFTQDVGQKGGVLDQHASYLEAKAALYDNIANLAVKVDSAMRLLETFTTTAT
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DNLNTSLVEAGEVYDQGLLKAIVIGIAVTIFAAAVGYHIAHSVREPLTRILSTLEGLANG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DMTQRIEIRYNNEFSRVSGHINTLADSLHDILVKLNDAAENLTDTAANNERTSSNAQNQL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
NAQREQTASVATAMTEMSHSVQEVAQSAQGSLEMVQKVESASESGRTIMSSNISTINQLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEHHCCHHHHHHHH
TRLNESVSAVSELQRMSGQIGSILDVIRNIAEQTNLLALNAAIEAARAGEQGRGFAVVAD
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCEEHHHHHHHHHHCCCCCCCEEEEHH
EVRVLASKTTQSTTEIESMISNLQSSSQSASHVIQSCMSDMEMSVEQASKANGAMEEIQA
HHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
LIIEISQMSTHISQAAAEQSETSTSIARSLEDINNIADRSYHAMAEIAATSESLSSLASQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTELVHRFKL
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]