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The map label for this gene is pta [H]

Identifier: 37680318

GI number: 37680318

Start: 2144915

End: 2147059

Strand: Direct

Name: pta [H]

Synonym: VV2134

Alternate gene names: 37680318

Gene position: 2144915-2147059 (Clockwise)

Preceding gene: 37680317

Following gene: 37680320

Centisome position: 63.94

GC content: 49.23

Gene sequence:

>2145_bases
ATGTCCCGTACTATTATGCTTATCCCTGCAAGTGCTGGTGTTGGTCTTACTAGCGTAAGCATGGGTGTTCTTCGCGCTAT
GGAGCGCAAAGGCGTTAAAGTTTCTTTCTACAAGCCTATCGCACAACCACGTAGCGGCGGTGATCTTCCTGATCTCACTA
CCACTATCGTTGGCGCAAACAGCGATATGAAGATTGGCGAACCCCTATTGATGTCTGTTGCTGAGAACCTAATCGGTAAC
GACAACATGGACGAACTGCTAGAAACGGTTGTAGAACGTTACAACCAAATTAATAAAGATGCAGACGTTACGCTAATCGA
AGGTCTTGTTCCTACTCGTAAGCACCCATTTGCTAACCAAGTGAACGCGGAAATCGCAGCAACACTTGGTGCTGAAATTG
TTCTTGTGGCGACCCCAGGCACTGACAACCCAGCACAGCTAAAAGAGCGTATCGAAGTGGCTTGTTCAAACTTCGGTGGC
ACGAAAAACAAAAACATCTCTGGTGTTATCATCAACAAGCTAAACGCGCCAGTTGATGAAGCAGGCCGTACGCGTCCTGA
TCTATCAGAGATCTTCGATGACGCAGACAGCGCGAAACAAAACCAGCTAGAAGTGATGCAAATCTTCAACTCTAGCCCAA
TTCGCGTTCTAGGTTGCGTGCCATGGAGCATCAACCTGATTGCAACTCGTGCAATCGATATGGCGAAGCACCTGAAAGCA
GAAGTGATCAACGAAGGCGACATCAACACTCGTCGTATTAAGAGCATCACCTTCTGTGCACGTTCTCTGCCACACATGAT
TGAGCACTTCAAACCAGGCTCACTGCTGGTGACTTCTGCTGACCGTCCAGACGTTATCGTTGCGGCTTCTCTAGCAGCAA
TGAACGGCGTGGAAATCGGTGCGGTACTTCTGACTGGCGGTTACGACATTCCTACAGAGATCGAAAACCTATGTAAGCCA
GCGTTTGAAAGTGGCCTTCCAATTTTCAAAGCACAAGGTAACACTTGGCAGACTTCGCTCAATCTACAGAGCTTCAGCCT
AGAAGTACCTGCAGACGATAAAGAGCGTATCGAGTTCATCAACGACCACGTTGCGGGTCACATCGATGGCAACTGGATTG
AGTCAATGACGGAAGGTACTGAGCGTTCTCGTCGCCTAAGTCCTCCAGCATTCCGTTACCAGTTGACTGAACTTGCTCGT
AAAGCGGGTAAACGCATCGTTCTTCCTGAAGGTGACGAACCACGTACTGTGAAAGCGGCAGCGATCTGTGCTGAACGCGG
TATCGCAGAATGTGTACTGCTAGGTAACCCTGAAGAGATCAAGCGCGTGGCAGCACAACAAGGTGTTGAACTGGGCGCTG
GCGTTAAGATCATCGATGCAGACGCGATTCGCGAAAACTACGTTGCTCGTCTTGTTGAACTACGTGGCTCGAAAGGCATG
ACTGAAGTTGTGGCTCGTGAGAAGCTGCAAGATTCTGTGTTCCTAGGCACTATGATGCTTGAGAACGATGAAGTTGACGG
TCTAGTATCTGGCGCGGTTCACACGACGGCAAACACCATCGTTCCTCCGTTCCAAATCATCAAGACAGCACCAAATGCGT
CTATCGTATCTTCTGTATTCTTCATGCTTCTGCCTGATCAAGTACTGGTTTACGGTGACTGTGCGATCAACCCAGATCCA
ACGGCAGAACAGCTTGCAGAAATCGCGATTCAATCTGCTGATTCTGCTGCAGCCTTTGGTATCGACCCACGCGTAGCAAT
GATCTCTTACTCTACTGGTGAATCTGGTAAGGGTGCAGACGTTGATAAAGTGCGTGAAGCGACCAAACTGGCTCAAGAGA
AACGTCCTGATCTGATCATCGACGGTCCTCTGCAGTACGACGCAGCGATCATGGAAAACGTGGCAGCGTCTAAAGCGCCT
AACTCTCCAGTAGCAGGTAAAGCGACTGTATTCGTATTCCCAGACCTCAACACGGGTAACACGACTTACAAAGCAGTACA
ACGTTCAGCAGACCTTGTTTCTATCGGTCCAATGCTGCAAGGTATGCGCAAGCCGGTAAACGACCTGTCTCGTGGCGCGC
TAGTCGACGATATCGTCTACACCATCGCTCTAACTGCAATCCAAGCGACTCAAGATCAGAAATAA

Upstream 100 bases:

>100_bases
TTTTTGATAAAGAATCTTGGGCTTCACTTCTATTGTTTGGTTCGCCAAACCATAAGCAGTAAAGCTTTAAATCCCCCAAT
AGTTAAAGGTACTTTCTCTG

Downstream 100 bases:

>100_bases
TCCACTGAATCTTTTGTCTCTTGTCAGCAAGACTGAGTAGCGATAGAACGAAAAAGGGGTTGGCACTATGCCAACCCCTT
TTGTTTTATGACTCATTCGG

Product: phosphate acetyltransferase

Products: NA

Alternate protein names: Phosphotransacetylase [H]

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MSRTIMLIPASAGVGLTSVSMGVLRAMERKGVKVSFYKPIAQPRSGGDLPDLTTTIVGANSDMKIGEPLLMSVAENLIGN
DNMDELLETVVERYNQINKDADVTLIEGLVPTRKHPFANQVNAEIAATLGAEIVLVATPGTDNPAQLKERIEVACSNFGG
TKNKNISGVIINKLNAPVDEAGRTRPDLSEIFDDADSAKQNQLEVMQIFNSSPIRVLGCVPWSINLIATRAIDMAKHLKA
EVINEGDINTRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAASLAAMNGVEIGAVLLTGGYDIPTEIENLCKP
AFESGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFINDHVAGHIDGNWIESMTEGTERSRRLSPPAFRYQLTELAR
KAGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIKRVAAQQGVELGAGVKIIDADAIRENYVARLVELRGSKGM
TEVVAREKLQDSVFLGTMMLENDEVDGLVSGAVHTTANTIVPPFQIIKTAPNASIVSSVFFMLLPDQVLVYGDCAINPDP
TAEQLAEIAIQSADSAAAFGIDPRVAMISYSTGESGKGADVDKVREATKLAQEKRPDLIIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQDQK

Sequences:

>Translated_714_residues
MSRTIMLIPASAGVGLTSVSMGVLRAMERKGVKVSFYKPIAQPRSGGDLPDLTTTIVGANSDMKIGEPLLMSVAENLIGN
DNMDELLETVVERYNQINKDADVTLIEGLVPTRKHPFANQVNAEIAATLGAEIVLVATPGTDNPAQLKERIEVACSNFGG
TKNKNISGVIINKLNAPVDEAGRTRPDLSEIFDDADSAKQNQLEVMQIFNSSPIRVLGCVPWSINLIATRAIDMAKHLKA
EVINEGDINTRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAASLAAMNGVEIGAVLLTGGYDIPTEIENLCKP
AFESGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFINDHVAGHIDGNWIESMTEGTERSRRLSPPAFRYQLTELAR
KAGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIKRVAAQQGVELGAGVKIIDADAIRENYVARLVELRGSKGM
TEVVAREKLQDSVFLGTMMLENDEVDGLVSGAVHTTANTIVPPFQIIKTAPNASIVSSVFFMLLPDQVLVYGDCAINPDP
TAEQLAEIAIQSADSAAAFGIDPRVAMISYSTGESGKGADVDKVREATKLAQEKRPDLIIDGPLQYDAAIMENVAASKAP
NSPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQDQK
>Mature_713_residues
SRTIMLIPASAGVGLTSVSMGVLRAMERKGVKVSFYKPIAQPRSGGDLPDLTTTIVGANSDMKIGEPLLMSVAENLIGND
NMDELLETVVERYNQINKDADVTLIEGLVPTRKHPFANQVNAEIAATLGAEIVLVATPGTDNPAQLKERIEVACSNFGGT
KNKNISGVIINKLNAPVDEAGRTRPDLSEIFDDADSAKQNQLEVMQIFNSSPIRVLGCVPWSINLIATRAIDMAKHLKAE
VINEGDINTRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAASLAAMNGVEIGAVLLTGGYDIPTEIENLCKPA
FESGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFINDHVAGHIDGNWIESMTEGTERSRRLSPPAFRYQLTELARK
AGKRIVLPEGDEPRTVKAAAICAERGIAECVLLGNPEEIKRVAAQQGVELGAGVKIIDADAIRENYVARLVELRGSKGMT
EVVAREKLQDSVFLGTMMLENDEVDGLVSGAVHTTANTIVPPFQIIKTAPNASIVSSVFFMLLPDQVLVYGDCAINPDPT
AEQLAEIAIQSADSAAAFGIDPRVAMISYSTGESGKGADVDKVREATKLAQEKRPDLIIDGPLQYDAAIMENVAASKAPN
SPVAGKATVFVFPDLNTGNTTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQDQK

Specific function: Conversion of acetate to acetyl-CoA; second step. [C]

COG id: COG0857

COG function: function code R; BioD-like N-terminal domain of phosphotransacetylase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788635, Length=714, Percent_Identity=74.7899159663866, Blast_Score=1112, Evalue=0.0,
Organism=Escherichia coli, GI1788800, Length=317, Percent_Identity=38.4858044164038, Blast_Score=215, Evalue=1e-56,
Organism=Escherichia coli, GI1788806, Length=347, Percent_Identity=30.5475504322767, Blast_Score=163, Evalue=3e-41,

Paralogues:

None

Copy number: 1420 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1250 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010766
- InterPro:   IPR016475
- InterPro:   IPR004614
- InterPro:   IPR002505 [H]

Pfam domain/function: PF07085 DRTGG; PF01515 PTA_PTB [H]

EC number: =2.3.1.8 [H]

Molecular weight: Translated: 76701; Mature: 76569

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRTIMLIPASAGVGLTSVSMGVLRAMERKGVKVSFYKPIAQPRSGGDLPDLTTTIVGAN
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEECC
SDMKIGEPLLMSVAENLIGNDNMDELLETVVERYNQINKDADVTLIEGLVPTRKHPFANQ
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHH
VNAEIAATLGAEIVLVATPGTDNPAQLKERIEVACSNFGGTKNKNISGVIINKLNAPVDE
CCHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AGRTRPDLSEIFDDADSAKQNQLEVMQIFNSSPIRVLGCVPWSINLIATRAIDMAKHLKA
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHHHH
EVINEGDINTRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAASLAAMNGVEIG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHHHCCCEEE
AVLLTGGYDIPTEIENLCKPAFESGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFI
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEEEEECCCCCHHHHHHH
NDHVAGHIDGNWIESMTEGTERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAA
HHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHH
AICAERGIAECVLLGNPEEIKRVAAQQGVELGAGVKIIDADAIRENYVARLVELRGSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCH
TEVVAREKLQDSVFLGTMMLENDEVDGLVSGAVHTTANTIVPPFQIIKTAPNASIVSSVF
HHHHHHHHHHHHHEEEEEEECCCCCCHHHHCCHHHCCCCCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIDPRVAMISYSTGESGKGAD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCCCCCC
VDKVREATKLAQEKRPDLIIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQDQK
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SRTIMLIPASAGVGLTSVSMGVLRAMERKGVKVSFYKPIAQPRSGGDLPDLTTTIVGAN
CCEEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCEEEEECC
SDMKIGEPLLMSVAENLIGNDNMDELLETVVERYNQINKDADVTLIEGLVPTRKHPFANQ
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHH
VNAEIAATLGAEIVLVATPGTDNPAQLKERIEVACSNFGGTKNKNISGVIINKLNAPVDE
CCHHHHEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHH
AGRTRPDLSEIFDDADSAKQNQLEVMQIFNSSPIRVLGCVPWSINLIATRAIDMAKHLKA
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEEECCCEEEEHHHHHHHHHHHHHH
EVINEGDINTRRIKSITFCARSLPHMIEHFKPGSLLVTSADRPDVIVAASLAAMNGVEIG
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHHHCCCEEE
AVLLTGGYDIPTEIENLCKPAFESGLPIFKAQGNTWQTSLNLQSFSLEVPADDKERIEFI
EEEEECCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEEEEEEEEEEEECCCCCHHHHHHH
NDHVAGHIDGNWIESMTEGTERSRRLSPPAFRYQLTELARKAGKRIVLPEGDEPRTVKAA
HHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHH
AICAERGIAECVLLGNPEEIKRVAAQQGVELGAGVKIIDADAIRENYVARLVELRGSKGM
HHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCH
TEVVAREKLQDSVFLGTMMLENDEVDGLVSGAVHTTANTIVPPFQIIKTAPNASIVSSVF
HHHHHHHHHHHHHEEEEEEECCCCCCHHHHCCHHHCCCCCCCCHHHHHCCCCHHHHHHHH
FMLLPDQVLVYGDCAINPDPTAEQLAEIAIQSADSAAAFGIDPRVAMISYSTGESGKGAD
HHHCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEECCCCCCEEEEEECCCCCCCCCC
VDKVREATKLAQEKRPDLIIDGPLQYDAAIMENVAASKAPNSPVAGKATVFVFPDLNTGN
HHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
TTYKAVQRSADLVSIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQATQDQK
HHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883769; 7918659; 9205837; 9278503; 2536666 [H]