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The map label for this gene is aspC [H]

Identifier: 37680280

GI number: 37680280

Start: 2104056

End: 2105255

Strand: Direct

Name: aspC [H]

Synonym: VV2096

Alternate gene names: 37680280

Gene position: 2104056-2105255 (Clockwise)

Preceding gene: 37680279

Following gene: 37680282

Centisome position: 62.72

GC content: 49.5

Gene sequence:

>1200_bases
ATGAAGATTATGTTTGAAAAAGTAGTTGCCGCTCCCGCGGACCCGATTCTTGGCCTAACTGAAGAATTCAAAAAAGACCC
TCGCGCAGAGAAAATTAACCTTGGCGTGGGTATCTACAAAACAGAACAAGGTGAAACGCCTGTTCTTGCTACGGTAAAGA
AAGCGGAAGCAGCGCTTGTTGAAACCGAGAAAACCAAATCTTACCTAACCATCGAAGGAACAGCAGAATACGCATTAGCG
GTTCAAAAACTGCTGTTTGGTGCAGATGCTGAGCTAATCAATGCGCAACGTGCAAAAACAGCACAAGCACCTGGCGGTAC
TGGCGCACTGCGCGTTGCAGGCGAATTCATCAAACGCCAACTCGGCGATGTAAAAATCTGGATCAGCAACCCAACTTGGG
CTAACCACCATGGTGTGTTCCGCGCAGCAGGCCTAGAAACGGTTGAGTACGCTTACTACAACCCAGAAACCAAAGACAAA
GACTTTGCCGCTATGCTGGCCGACCTTGAAAAAGCGTCCGCTGGTGATGTGGTACTGCTGCACGGATGTTGCCATAACCC
AACAGGCATCGACCCAACAGCACAAGAGTGGGAAGCGCTTGCTAAACTGGTTGCCGACAAGGGCCTACTTCCACTATTTG
ACTTTGCCTACCAAGGTTTCGCGAAAGGTGTTGAAGAAGATGCGCAAGGCCTACGTACCTTCGCTAAATTCAACAAAGAG
ATCCTTGTAGCAAGTTCATTCTCGAAAAACTTTGGTCTGTACAACGAGCGTGTAGGCGCATTCACGTTAGTGGCTGAAAG
CCAAGAGATCGCTGAAACGGCATTCTCACAAGTGAAAGCGATCATTCGCTCTATCTACTCAAACCCACCAGCGCACGGCA
GTGCGGTAGTGACTCACATCCTTAACGATGCAGCGCTTCGTGCAGAGTGGGAAGCGGAAGTGGCAGAGATGCGCGATCGC
ATCCAAGAGATGCGCGAGCTTTTTGTGGCAACACTGAAAGAAGAAGGCGTAGCGGCTGACTTTAGCTTTATCGAGCGTCA
AAACGGCATGTTCTCTTTCTCTGGTTTGAACAAAGATCAAGTGGCTCGTCTAAAAGAAGAGTTTGCGATCTACATCGTGG
GTTCTGGTCGCATCAGCGTTGCGGGCATGACCAAATCCAACATGGGTCCGCTTTGTAAAGCCATCGCTGCGGTACTGTAA

Upstream 100 bases:

>100_bases
CGGTTAGGCTTAAATGCTGTTATGTGAATGCCTGATTATGTTTCATGGTCTCGCTGGGCCCTGAAACATAAACAGACCTA
CCCCCTTCGATTTAACATGG

Downstream 100 bases:

>100_bases
TTCGCAAGATGATGATAAAAAGGCCGTTCAAACGGCCTTTTTTGTTTGTGAACGCTTACGCTAATAGACCCACTTAAGGG
AGATGCCTGCTTCATTGATG

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKIMFEKVVAAPADPILGLTEEFKKDPRAEKINLGVGIYKTEQGETPVLATVKKAEAALVETEKTKSYLTIEGTAEYALA
VQKLLFGADAELINAQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHHGVFRAAGLETVEYAYYNPETKDK
DFAAMLADLEKASAGDVVLLHGCCHNPTGIDPTAQEWEALAKLVADKGLLPLFDFAYQGFAKGVEEDAQGLRTFAKFNKE
ILVASSFSKNFGLYNERVGAFTLVAESQEIAETAFSQVKAIIRSIYSNPPAHGSAVVTHILNDAALRAEWEAEVAEMRDR
IQEMRELFVATLKEEGVAADFSFIERQNGMFSFSGLNKDQVARLKEEFAIYIVGSGRISVAGMTKSNMGPLCKAIAAVL

Sequences:

>Translated_399_residues
MKIMFEKVVAAPADPILGLTEEFKKDPRAEKINLGVGIYKTEQGETPVLATVKKAEAALVETEKTKSYLTIEGTAEYALA
VQKLLFGADAELINAQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHHGVFRAAGLETVEYAYYNPETKDK
DFAAMLADLEKASAGDVVLLHGCCHNPTGIDPTAQEWEALAKLVADKGLLPLFDFAYQGFAKGVEEDAQGLRTFAKFNKE
ILVASSFSKNFGLYNERVGAFTLVAESQEIAETAFSQVKAIIRSIYSNPPAHGSAVVTHILNDAALRAEWEAEVAEMRDR
IQEMRELFVATLKEEGVAADFSFIERQNGMFSFSGLNKDQVARLKEEFAIYIVGSGRISVAGMTKSNMGPLCKAIAAVL
>Mature_399_residues
MKIMFEKVVAAPADPILGLTEEFKKDPRAEKINLGVGIYKTEQGETPVLATVKKAEAALVETEKTKSYLTIEGTAEYALA
VQKLLFGADAELINAQRAKTAQAPGGTGALRVAGEFIKRQLGDVKIWISNPTWANHHGVFRAAGLETVEYAYYNPETKDK
DFAAMLADLEKASAGDVVLLHGCCHNPTGIDPTAQEWEALAKLVADKGLLPLFDFAYQGFAKGVEEDAQGLRTFAKFNKE
ILVASSFSKNFGLYNERVGAFTLVAESQEIAETAFSQVKAIIRSIYSNPPAHGSAVVTHILNDAALRAEWEAEVAEMRDR
IQEMRELFVATLKEEGVAADFSFIERQNGMFSFSGLNKDQVARLKEEFAIYIVGSGRISVAGMTKSNMGPLCKAIAAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=43.4343434343434, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI4504067, Length=393, Percent_Identity=40.9669211195929, Blast_Score=303, Evalue=1e-82,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=27.154046997389, Blast_Score=154, Evalue=1e-37,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.6262626262626, Blast_Score=533, Evalue=1e-153,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=45.088161209068, Blast_Score=360, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI71981858, Length=395, Percent_Identity=44.8101265822785, Blast_Score=358, Evalue=3e-99,
Organism=Caenorhabditis elegans, GI25147133, Length=398, Percent_Identity=40.7035175879397, Blast_Score=321, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI17569539, Length=395, Percent_Identity=36.2025316455696, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17569537, Length=387, Percent_Identity=31.266149870801, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.2205323193916, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI25147136, Length=214, Percent_Identity=37.8504672897196, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323055, Length=405, Percent_Identity=36.7901234567901, Blast_Score=286, Evalue=5e-78,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=33.4883720930233, Blast_Score=247, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24580970, Length=396, Percent_Identity=41.4141414141414, Blast_Score=324, Evalue=6e-89,
Organism=Drosophila melanogaster, GI24580972, Length=396, Percent_Identity=41.4141414141414, Blast_Score=324, Evalue=8e-89,
Organism=Drosophila melanogaster, GI24654046, Length=399, Percent_Identity=41.8546365914787, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI19922362, Length=399, Percent_Identity=41.8546365914787, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI19920542, Length=390, Percent_Identity=41.5384615384615, Blast_Score=321, Evalue=6e-88,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43422; Mature: 43422

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIMFEKVVAAPADPILGLTEEFKKDPRAEKINLGVGIYKTEQGETPVLATVKKAEAALV
CCCHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEECEEEEECCCCCCCCEEHHHHHHHHHH
ETEKTKSYLTIEGTAEYALAVQKLLFGADAELINAQRAKTAQAPGGTGALRVAGEFIKRQ
HHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LGDVKIWISNPTWANHHGVFRAAGLETVEYAYYNPETKDKDFAAMLADLEKASAGDVVLL
HCCEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTAQEWEALAKLVADKGLLPLFDFAYQGFAKGVEEDAQGLRTFAKFNKE
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCE
ILVASSFSKNFGLYNERVGAFTLVAESQEIAETAFSQVKAIIRSIYSNPPAHGSAVVTHI
EEEEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LNDAALRAEWEAEVAEMRDRIQEMRELFVATLKEEGVAADFSFIERQNGMFSFSGLNKDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCHHH
VARLKEEFAIYIVGSGRISVAGMTKSNMGPLCKAIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC
>Mature Secondary Structure
MKIMFEKVVAAPADPILGLTEEFKKDPRAEKINLGVGIYKTEQGETPVLATVKKAEAALV
CCCHHHHHHCCCCCCCCCCHHHHCCCCCCCEEEECEEEEECCCCCCCCEEHHHHHHHHHH
ETEKTKSYLTIEGTAEYALAVQKLLFGADAELINAQRAKTAQAPGGTGALRVAGEFIKRQ
HHHCCCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
LGDVKIWISNPTWANHHGVFRAAGLETVEYAYYNPETKDKDFAAMLADLEKASAGDVVLL
HCCEEEEECCCCCCCCCCCEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTAQEWEALAKLVADKGLLPLFDFAYQGFAKGVEEDAQGLRTFAKFNKE
ECCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCE
ILVASSFSKNFGLYNERVGAFTLVAESQEIAETAFSQVKAIIRSIYSNPPAHGSAVVTHI
EEEEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LNDAALRAEWEAEVAEMRDRIQEMRELFVATLKEEGVAADFSFIERQNGMFSFSGLNKDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEECCCCHHH
VARLKEEFAIYIVGSGRISVAGMTKSNMGPLCKAIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]